Individual Susceptibility To Genotoxic Agents In The Human Population

DOWNLOAD

Download Individual Susceptibility To Genotoxic Agents In The Human Population PDF/ePub or read online books in Mobi eBooks. Click Download or Read Online button to get Individual Susceptibility To Genotoxic Agents In The Human Population book now. This website allows unlimited access to, at the time of writing, more than 1.5 million titles, including hundreds of thousands of titles in various foreign languages. If the content not found or just blank you must refresh this page

Individual Susceptibility To Genotoxic Agents In The Human Population

DOWNLOAD
Author : Frederick J. De Serres
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Individual Susceptibility To Genotoxic Agents In The Human Population written by Frederick J. De Serres and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.

As a result of the industrial revolution, man's technological achievements have been truly great, increasing the quality of life to almost unimagined proportions; but all this progress has not been accomplished without equally un imagined health risks. Sufficiently diagnostic short-term assay procedures have been developed in recent years for us to determine that there are mutagenic agents among thou sands of chemicals to which the human population is exposed today. These chemicals were not significantly present prior to the indus trial revolution. As of today, there are no procedures available which have been adequately demonstrated to assess individual sus ceptibility to genotoxic exposures, and as a result we have had to rely on extrapolating toxicological data from animal model systems. The question is can we afford to allow such an increased environ mental selection pressure via mutagenic exposures to occur without expecting adverse long-term effects on our health. It is apparent from this line of reasoning that what is lacking and immediately needed are test procedures that can be applied to humans to assess genotoxic exposure as well as individual susceptibility to it. There have already been two conferences which have focused at tention on this research area. "Guidelines for studies of human populations exposed to mutagenic and reproductive hazards" (A. D. Bloom, ed., March of Dimes Birth Defects Foundation, White Plains, New York, 1981) and "Indicators of genotoxic exposure in humans" (Banbury Report 13, B. A. Bridges, B. E. Butterworth, and I. B.

Individual Susceptibility To Genotoxic Agents In The Human Population Volume 30

DOWNLOAD
Author : FJ de Serres (Ed)
language : en
Publisher:
Release Date : 1984

Individual Susceptibility To Genotoxic Agents In The Human Population Volume 30 written by FJ de Serres (Ed) and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1984 with categories.

Journal Of The National Cancer Institute

DOWNLOAD
Author :
language : en
Publisher:
Release Date : 1996

Journal Of The National Cancer Institute written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996 with Cancer categories.

Age And Susceptibility To Toxic Substances

DOWNLOAD
Author : Edward J. Calabrese
language : en
Publisher: Wiley-Interscience
Release Date : 1986-09-22

Age And Susceptibility To Toxic Substances written by Edward J. Calabrese and has been published by Wiley-Interscience this book supported file pdf, txt, epub, kindle and other format this book has been release on 1986-09-22 with Medical categories.

Investigates the relationship between age and environmentally induced diseases, which must be taken into consideration in establishing acceptable exposure standards for high-risk groups in society. Assesses the effect of age on gastrointestinal and dermal absorption of toxic substances and drugs, and age differences in plasma protein binding and xenobiotic metabolism. Contains several chapters on organ-specific toxicity differences according to age. Also discusses genotoxicity and environmentally induced cancer. A final chapter synthesizes the information and addresses the relevance of this knowledge to biological basis of safety considerations.

Nih Publication

DOWNLOAD
Author :
language : en
Publisher:
Release Date : 1983

Nih Publication written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1983 with categories.

Current Catalog

DOWNLOAD
Author : National Library of Medicine (U.S.)
language : en
Publisher:
Release Date :

Current Catalog written by National Library of Medicine (U.S.) and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on with Medicine categories.

First multi-year cumulation covers six years: 1965-70.

Ehp

DOWNLOAD
Author :
language : en
Publisher:
Release Date : 1993

Ehp written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993 with Environmental health categories.

National Institutes Of Health Annual Report Of International Activities

DOWNLOAD
Author : John E. Fogarty International Center for Advanced Study in the Health Sciences
language : en
Publisher:
Release Date : 1982

National Institutes Of Health Annual Report Of International Activities written by John E. Fogarty International Center for Advanced Study in the Health Sciences and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1982 with Medicine categories.

Re Evaluation Of The Pathology Findings Of Studies On Nitrite And Cancer

DOWNLOAD
Author : Universities Associated for Research and Education in Pathology
language : en
Publisher:
Release Date : 1980

Re Evaluation Of The Pathology Findings Of Studies On Nitrite And Cancer written by Universities Associated for Research and Education in Pathology and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1980 with Cancer categories.

Short Term Bioassays In The Analysis Of Complex Environmental Mixtures Iv

DOWNLOAD
Author : Michael Waters
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-11

Short Term Bioassays In The Analysis Of Complex Environmental Mixtures Iv written by Michael Waters and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-11 with Science categories.

With this proceedings of the fourth symposium on complex mixtures, we continue to revise and extend our knowledge of genetic methods for the evaluation of chemical mixtures in the environment. The early chapters of this volume are devoted to new bioassay techniques that are directly applicable to the monitoring of environments contaminated with genotoxic chemicals. Microbiological methods have been further refined to meet the special needs of atmospheric monitoring so that very small samples may now be efficiently tested. New in situ methods utilizing green plants actually avoid many of the usual difficulties of sample collection and preparation and offer special advantages in monitoring wastewater, sludges, and hazardous wastes. Insects also are being employed very effectively in the evaluation of gaseous air pollutants in controlled laboratory investigations. Increased emphasis has been placed on a comprehensive assessment of the potential of complex mixtures t9 cause various kinds of genetic damage. New assays for chromosome structural and numerical aberrations in mammalian cells in vitro have been developed and are being applied in laboratory studies. Efforts to link tests for gene mutation and cell transformation in vitro with assays for tumorigenesis in vivo are contributing to the validation of the short-term testing approach. Studies comparing in vitro and in vivo data on a coal conversion by-product, on polycyclic aromatic hydrocarbons, and on mineral fibers are reported in separate papers. Later chapters are devoted to investigations on the fractionation and biological evaluation of specific chemical components within complex mixtures.