Inhibitors In Patients With Haemophilia

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Inhibitors In Patients With Haemophilia

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Author : E. C. Rodriquez-Merchan
language : en
Publisher: John Wiley & Sons
Release Date : 2008-04-15

Inhibitors In Patients With Haemophilia written by E. C. Rodriquez-Merchan and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-04-15 with Medical categories.

Edited by an orthopaedic surgeon and a haematologist who are leading specialists in the treatment of haemophilia, Inhibitors in Patients with Haemophilia reviews the different haemostatic products and protocols for the control of bleeding and surgery in haemophilic patients with inhibitors. The book draws together in a single volume all of the clinical issues involved in the treatment of inhibitors from numerous specialists worldwide. It will be an invaluable resource for all those treating inhibitors in people with haemophilia.

Inhibitors To Coagulation Factors

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Author : Louis M. Aledort
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Inhibitors To Coagulation Factors written by Louis M. Aledort and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.

"For the blood is the life . . . . "(Deut. 12 :23) " . . . because the blood, in its value as life, makes atonement" (Lev. 17: 11) HemoPhilia is a rare disease, severe hemophilia rarer still, yet the written history of hemophilia extends back over a millennium and a half. In the ancient Middle East, blood and life were coupled. Blood was the primary substance necessary for life, given to God in sacrifice and forbidden as a food to mortals by Levitical law. Blood was essential for rites of purification and consecration. But the flow of blood during menstruation or parturition rendered a woman unclean. The circumcision of a male child required 33 days of "blood purification" by the mother. ' Circumcision, the visible reminder of the covenant of Abraham lijith Yahweh, was required of newborn Jewish males. It "connote(d) suitability for participation in what God is doing. "2 Hence, free and uncontrolled bleeding of the male child during circumcision, during the ratification of God's covenant, would be noted with awe and concern by those of the Jewish faith. It should not be surprising that the first genetic counseling offered to families with hemophilia is found in the Babylonian Talmud (compilation of Jewish law dated to about the third century AD) and concerns the necessity for circumcision in families with what we would now call hemophilia.

Textbook Of Hemophilia

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Author : Christine A. Lee
language : en
Publisher: John Wiley & Sons
Release Date : 2011-07-05

Textbook Of Hemophilia written by Christine A. Lee and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-07-05 with Medical categories.

The Textbook of Hemophilia has become a definitive resource for all those managing hemophilia patients. It covers all the common and rare bleeding disorders, both in terms of clinical management as well as the genetic, laboratory, financial and psychological aspects. This second edition covers all the latest developments in the field of hemophilia, with new chapters on: the genetic and molecular basis of inherited blood disorders how to manage adolescent and older patients emergency medicine and inherited blood disorders national hemophilia databases Drawing on the vast experience of the authors, the aim of this textbook remains the same - to improve the care of patients suffering from hemophilia. The book is full of detailed guidance and advice on everyday clinical questions making it invaluable to all trainee and practicing hematologists.

Insight In Risk Factors And Treatment Of Inhibitors In Nonsevere Hemophilia A

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Author : Alice Sophie Velzen
language : en
Publisher:
Release Date : 2016

Insight In Risk Factors And Treatment Of Inhibitors In Nonsevere Hemophilia A written by Alice Sophie Velzen and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016 with categories.

Hemophilia A is an inherited X-linked bleeding disorder that occurs in male offspring of carrier females. In these individuals a mutation in the F8 gene, located on the X-chromosome, causes a deficiency of the factor VIII protein, clotting factor VIII. The worldwide prevalence of hemophilia is 1 in 5000 live male births, with one-third of the patients affected by severe hemophilia A and two-thirds of the patients have nonsevere disease. In patients with hemophilia A there is an impaired hemostasis due to a reduction of their factor VIII plasma level. This is associated with clinical symptoms of spontaneous bleeds in joints and muscles. An extremely severe and challenging complication of treatment with factor VIII concentrates in hemophilia A patients is the development of anti-factor VIII antibodies that inhibit (neutralize) the factor VIII activity, also referred to as inhibitors. This complication occurs in 25-30% of the severe hemophilia patients. Inhibitors seem to occur less frequently in nonsevere hemophilia A patients, although studies on inhibitor incidence in this group of patients are scarce. When a nonsevere hemophilia A patient develops an inhibitor, the phenotype of the disease may change dramatically. Nonsevere haemophilia A patients would normally only experience incidental bleeding episodes, but after inhibitor development the bleeding phenotype may aggravate dramatically, especially if the inhibitor reduces the endogenous factor VIII plasma levels. This is associated with an increased morbidity and mortality. This thesis focuses on the risk factors and treatment of inhibitors in nonsevere hemophilia A.

Current And Future Issues In Hemophilia Care

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Author : Emérito Carlos Rodríguez-Merchán
language : en
Publisher: John Wiley & Sons
Release Date : 2011-04-27

Current And Future Issues In Hemophilia Care written by Emérito Carlos Rodríguez-Merchán and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-04-27 with Medical categories.

As haemophilia is a life-long condition, continuing supervision by a group of medical personnel is required. In many countries this is provided by comprehensive care haemophilia centres where staff of all specialities concerned with treatment- haematologists, paediatricians, nurses, physiotherapists, orthopaedic surgeons - have specialized knowledge. This new book is a definitive resource on the current aspects and issues around haemophilia. Complications of haemophilia care are well covered in chapters on inhibitors, and musculoskeletal problems, as are all the latest developments in the field of haemophilia.

Comorbidities And Inhibitors In Adult Patients With Haemophilia

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Author : Erik Berntorp
language : en
Publisher:
Release Date : 2015

Comorbidities And Inhibitors In Adult Patients With Haemophilia written by Erik Berntorp and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015 with categories.

Haemophilia

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Author :
language : en
Publisher:
Release Date : 2001

Haemophilia written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001 with categories.

Textbook Of Hemophilia

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Author : Christine A. Lee
language : en
Publisher: John Wiley & Sons
Release Date : 2008-04-15

Textbook Of Hemophilia written by Christine A. Lee and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-04-15 with Medical categories.

The only up-to-date definitive reference source onhemophilia This book is an invaluable resource that provides an overview ofall aspects of the care of patients with haemophilia. Covering how to assess both bleeding children and adults,Haemophilia A and B, molecular basis of the disease, the role offactors in coagulation, epidemiology, pharmacokinetics, andtreatment of inhibitors. There will also be a section onmusculoskeletal aspects of haemophilia as well as newerdevelopments such as gene therapy and rare bleedingdisorders. Textbook of Hemophilia is ideal for: Trainees and residents in hematology Hematologists in practice Specialists working in thrombosis and hemostasis as well astransfusion medicine Why Buy This Book? The only up-to-date definitive reference source onhemophilia Essential for all those managing hemophilia patients Detailed guidance on assessment, diagnosis, management andtreatment Advice for everyday clinical questions Edited by three of the world’s leading experts onhemophilia

Hemophilia

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Author : Angelika Batorova
language : en
Publisher: BoD – Books on Demand
Release Date : 2012-03-30

Hemophilia written by Angelika Batorova and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-03-30 with Medical categories.

This book demonstrates the great efforts aimed at further improving the care of the hemophilia, which may bring further improvement in the quality of life of hemophilia persons and their families.

Orthopedic Surgery In Patients With Hemophilia

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Author : Horacio A. Caviglia
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-10-17

Orthopedic Surgery In Patients With Hemophilia written by Horacio A. Caviglia and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-10-17 with Medical categories.

Edited by two leading orthopedic surgeons who are specialists in the treatment of hemophilia, Orthopedic Surgery in Patients with Hemophilia shows all the surgical techniques needed for surgical treatment of musculoskeletal complications of hemophilia. A practical guide, designed for use on the ward or in the office, this book draws on the experience of numerous specialists worldwide, from developed and developing countries. As well as orthopedic surgery, it also covers research, hematology, and rehabilitation. Although of primary interest to the orthopedic surgeon, rheumatologist, and physiotherapist, this book will also be relevant to the hematologist responsible for the care of the hemophiliac patient.