Interferon The Dawn Of Recombinant Protein Drugs
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Interferon The Dawn Of Recombinant Protein Drugs
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Author : J. Lindenmann
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-06-29
Interferon The Dawn Of Recombinant Protein Drugs written by J. Lindenmann and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-29 with Medical categories.
Forty years of Interferon I wish to dedicate this short introduction to the memory of Alick Isaacs (1921-1967), and to that of Sir Christopher Andrewes (1896-1988). Let us go back more than 40 years. In 1956 Isaacs was in charge of the Wodd Influenza Centre. Andrewes was head of the division of bac teriology and virology, and deputy director of the National Institute for Medical Research in London. When researchers are faced with a seemingly new phenomenon, ex planations are easy to come by. These explanations fall into two broad categories: the phenomenon in question is either due to something or to the lack of something. I apologize for the primitive way in which I ex press this, but I am going to give three examples, scattered over 100 years, of what I mean. First example: in 1880 the great French microbiologist Louis Pas teur was involved in work on chicken cholera. He was struck by the following observation: if a suitable chicken broth was inoculated with the bacterium, the organism grew profusely and the liquid became tur bid. If he now freed the fluid, by sedimentation or filtration, from the bulk of the organisms and re-inoculated it with the same bacterium, no growth occurred.
Interferon
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Author : Toine Pieters
language : en
Publisher: Routledge
Release Date : 2005
Interferon written by Toine Pieters and has been published by Routledge this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with Interferon categories.
This book charts the history and development of one of the most important medical substances of the twentieth century, Interferon, as a drug.
Interferon The 50th Anniversary
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Author : Paula M. Pitha
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-08-29
Interferon The 50th Anniversary written by Paula M. Pitha and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-08-29 with Medical categories.
A vital text for researchers and clinicians in the fields of virology and oncology alike, this book is a comprehensive guide to one of medicine’s most important tools that covers the most recent research. Important insights have been made in recent months that are challenging the accepted concept of the critical role of dsRNA in IFN induction. Recent work with genetically modified mice seems to confirm the original idea that interferon is the first cellular defense against viral infection.
A History Of Biochemistry
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Author : Marcel Florkin
language : en
Publisher: Gulf Professional Publishing
Release Date : 1972
A History Of Biochemistry written by Marcel Florkin and has been published by Gulf Professional Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 1972 with Biochemistry categories.
The Western Medical Tradition
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Author : W. F. Bynum
language : en
Publisher: Cambridge University Press
Release Date : 2006-03-20
The Western Medical Tradition written by W. F. Bynum and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-03-20 with History categories.
This book, first published in 2006, is an authoritative description of the important changes in Western medicine over the past two centuries.
The Role Of Natural Products In Drug Discovery
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Author : J. Mulzer
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-04-17
The Role Of Natural Products In Drug Discovery written by J. Mulzer and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-04-17 with Medical categories.
Natural Products have been important sources of useful drugs from prehistoric times to the present. This book gives an overview about this field and provides important recent contributions to the discovery of new drugs generated by research on natural products. Total synthesis of natural products with interesting biological activities is paving the way for the preparation of new and improved analogs. The methods of combinatorial chemistry permit the selection of the best drug from a large number of candidates. Beyond synthesis and evaluation of organic molecules a number of new bioorganic methods are coming to the fore and will be discucced in this isue of the ERnst schering Research Foundation workshop proceedings.
Appropriate Dose Selection How To Optimize Clinical Drug Development
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Author : J. Venitz
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-03-06
Appropriate Dose Selection How To Optimize Clinical Drug Development written by J. Venitz and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-03-06 with Medical categories.
Optimal dose individualization has become more important in improving clinical efficacy and safety. This is due in part to the variability in drug response. Therefore, the role of optimal dose finding in early clinical drug development so as to maximize successful clinical use is emphasized. This book reviews innovative methods, tools and examples of rational drug development strategies, particularly for novel oncological agents.
Small Molecule Protein Interactions
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Author : Herbert Waldmann
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-09
Small Molecule Protein Interactions written by Herbert Waldmann and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-09 with Medical categories.
Based on the international workshop on 'Small Molecule - Protein Interactions' held in Berlin, April 24-26, 2002, researchers from industry and academic laboratories describe novel and efficient ways selecting promising new drug targets and developing small molecule inhibitors against them. The structure of the book corresponds to the different aspects of the drug discovery process. All chapters are written by leading experts in the field, who present and discuss the most recent state-of-the-art tools and techniques for the development of novel drugs. The value of the book lies in surveying and summarizing the approaches taken by different companies and institutions giving the reader a balanced view on the use of the latest techniques on the one hand and experience-based assistance in selecting appropriate tools for their own work on the other hand.
The Promises And Challenges Of Regenerative Medicine
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Author : John Morser
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-01-19
The Promises And Challenges Of Regenerative Medicine written by John Morser and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-01-19 with Science categories.
Presents the advances in stem cell research. This book discusses the analysis and use of stem cells in basic biology, and their application in clinical practice.
New Mechanisms For Tissue Selective Estrogen Free Contraception
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Author : H.B. Croxatto
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-01-19
New Mechanisms For Tissue Selective Estrogen Free Contraception written by H.B. Croxatto and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-01-19 with Medical categories.
Combined oral contraceptives are the most convenient and accepted method of hormonal contraception. Nevertheless, the medical community and consumers constantly demand innovation, additional benefits during use and lower hormonal load despite the high safety profile of available products. At the Ernst Schering Research Foundation Workshop 52, new perspectives and mechanisms for tissue-selective, estrogen-free contraception were discussed. The aim of the workshop was to bring together experts in the field of molecular and pharmacodynamic action of progestins with clinicians and medical experts to discuss potential medical endpoints, physiological reactions and (bio)marker useful describing the tissue selectivity and the contraceptive action of new progestins in different target organs. A major factor for successful realization of these new concepts is a deeper understanding of local pharmacological responses to progestins in general and to new progestins in particular.