Interleukin 12
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Interleukin 12
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Author : Michael T. Lotze
language : en
Publisher:
Release Date : 1996
Interleukin 12 written by Michael T. Lotze and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996 with Medical categories.
This work focuses on the understanding of IL-12, including its production, receptor interactions, signal transduction, interactions with other cytokines, its use as a therapy for AIDS and cancer, and its role in promoting an effective cellular response to microbial pathogens.
Interleukin 12 Antitumor Activity And Immunotherapeutic Potential In Oncology
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Author : Witold Lasek
language : en
Publisher: Springer
Release Date : 2016-09-23
Interleukin 12 Antitumor Activity And Immunotherapeutic Potential In Oncology written by Witold Lasek and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-09-23 with Medical categories.
This book discusses the immunotherapeutic potential of Interleukin 12 in the context of clinical oncology, as well as antitumor effects confirmed in preclinical studies and clinical trials in cancer immunotherapy. Due to its ability to activate both innate (NK cells) and adaptive (cytotoxic T lymphocytes) immunities, Interleukin 12 (IL-12) has been regarded as a promising candidate for tumor immunotherapy. However, despite the encouraging results in animal models, only very modest antitumor effects have been confirmed in early clinical trials. Recently, several clinical studies have been initiated in which IL-12 was applied as an adjuvant in cancer vaccines, in gene therapy including locoregional injections of IL-12 plasmid, and in the form of tumor-targeting immunocytokines (IL-12 fused to monoclonal antibodies).
Interleukin Twelve
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Author : Luciano Adorini
language : en
Publisher: S Karger Ag
Release Date : 1997
Interleukin Twelve written by Luciano Adorini and has been published by S Karger Ag this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997 with Medical categories.
The contributions collected in this volume represent the most recent findings, reviewed by leading scientists in the field, on several different aspects of IL-12 biology. The opening chapter analyzes the molecular regulation of IL-12 production and its immunomodulatory activities. This is followed by three contributions describing the structure of the IL-12 receptor and its role in determining the early events in the differentiation of T cell subsets. The modulation of IL-12 activities by other cytokines such as TGF-Beta, IFN-Gamma and IL-4 is also addressed. IL-12 is a key cytokine that controls infectious diseases and its role in leishmania, candida, and protozoal infections is specifically examined. In addition, IL-12 provides a new tool to explore the regulatory role of the immune system in the control of tumor development and a potential new drug which is already being tested in clinical trials. Finally, the role of IL-12 in Th1-mediated autoimmune diseases and the potential for immunotherapy based on IL-12 targeting is discussed. Collectively, these contributions give a detailed account of the present knowledge on critical aspects of IL-12. The well-edited and stimulating material offered in this volume will be of interest to all immunologists, in particular to those interested in the different facets of the Th1/Th2 dichotomy.
The Roles Of Interleukin 12 As A Third Signal For Clonal Expansion And Cytolytic Function Of Na Ve Cd8 T Cells
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Author : Javier Valenzuela
language : en
Publisher:
Release Date : 2003
The Roles Of Interleukin 12 As A Third Signal For Clonal Expansion And Cytolytic Function Of Na Ve Cd8 T Cells written by Javier Valenzuela and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003 with Interleukin-12 categories.
Interleukin 12 And Interferon Alpha Beta Mediated Gene Regulation In Programming Cd8 T Cell Differentiation
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Author : Pujya Agarwal
language : en
Publisher:
Release Date : 2007
Interleukin 12 And Interferon Alpha Beta Mediated Gene Regulation In Programming Cd8 T Cell Differentiation written by Pujya Agarwal and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with Cell differentiation categories.
Role Of Interleukin 12 And Interleukin 18 In Murine Immune Cell Regulation
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Author : Habiba Chakir
language : en
Publisher:
Release Date : 2003
Role Of Interleukin 12 And Interleukin 18 In Murine Immune Cell Regulation written by Habiba Chakir and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003 with Interleukin-12 categories.
Molecular Principles Of Interleukin 12 Family Cytokine Biogenesis And Their Exceptions For Interleukin 35
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Author : Karen Hildenbrand
language : en
Publisher:
Release Date : 2022
Molecular Principles Of Interleukin 12 Family Cytokine Biogenesis And Their Exceptions For Interleukin 35 written by Karen Hildenbrand and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022 with categories.
Mechanisms Of Interleukin 12 Tumor Therapy
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Author : Christina M. Coughlin
language : en
Publisher:
Release Date : 1999
Mechanisms Of Interleukin 12 Tumor Therapy written by Christina M. Coughlin and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999 with categories.
The Role Of Interleukin 12 In The Pathogenesis Of Sendai Virus Induced Airway Disease
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Author : Amy Elizabeth Seymour Stone
language : en
Publisher:
Release Date : 2002
The Role Of Interleukin 12 In The Pathogenesis Of Sendai Virus Induced Airway Disease written by Amy Elizabeth Seymour Stone and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with categories.
The Role Of The Interleukin 12 Family In Atherosclerosis
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Author :
language : en
Publisher:
Release Date : 2014
The Role Of The Interleukin 12 Family In Atherosclerosis written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014 with categories.