Investigating Chromosomes
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Investigating Chromosomes
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Author : A. F. Dyer
language : en
Publisher: Hodder Education
Release Date : 1979
Investigating Chromosomes written by A. F. Dyer and has been published by Hodder Education this book supported file pdf, txt, epub, kindle and other format this book has been release on 1979 with Chromosomes categories.
Investigating Chromosomes
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Author : Adrien F. Dyer
language : en
Publisher: Gower Publishing Company, Limited
Release Date : 1979
Investigating Chromosomes written by Adrien F. Dyer and has been published by Gower Publishing Company, Limited this book supported file pdf, txt, epub, kindle and other format this book has been release on 1979 with Chromosomes categories.
Chromosomes
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Author : Adrian T. Sumner
language : en
Publisher: John Wiley & Sons
Release Date : 2008-04-30
Chromosomes written by Adrian T. Sumner and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-04-30 with Science categories.
Integrating classical knowledge of chromosome organisation with recent molecular and functional findings, this book presents an up-to-date view of chromosome organisation and function for advanced undergraduate students studying genetics. The organisation and behaviour of chromosomes is central to genetics and the equal segregation of genes and chromosomes into daughter cells at cell division is vital. This text aims to provide a clear and straightforward explanation of these complex processes. Following a brief historical introduction, the text covers the topics of cell cycle dynamics and DNA replication; mitosis and meiosis; the organisation of DNA into chromatin; the arrangement of chromosomes in interphase; euchromatin and heterochromatin; nucleolus organisers; centromeres and telomeres; lampbrush and polytene chromosomes; chromosomes and evolution; chromosomes and disease, and artificial chromosomes. Topics are illustrated with examples from a wide variety of organisms, including fungi, plants, invertebrates and vertebrates. This book will be valuable resource for plant, animal and human geneticists and cell biologists. Originally a zoologist, Adrian Sumner has spent over 25 years studying human and other mammalian chromosomes with the Medical Research Council (UK). One of the pioneers of chromosome banding, he has used electron microscopy and immunofluorescence to study chromosome organisation and function, and latterly has studied factors involved in chromosome separation at mitosis. Adrian is an Associate Editor of the journal Chromosome Research, acts as a consultant biologist and is also Chair of the Committee of the International Chromosome Conferences. The most up-to-date overview of chromosomes in all their forms. Introduces cutting-edge topics such as artificial chromosomes and studies of telomere biology. Describes the methods used to study chromosomes. The perfect complement to Turner.
An Investigation Of Human Chromosomes Using Flourescent Microscopy
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Author : Sally Jean Cullen
language : en
Publisher:
Release Date : 1972
An Investigation Of Human Chromosomes Using Flourescent Microscopy written by Sally Jean Cullen and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1972 with Human chromosomes categories.
Chromosome Architecture
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Author : Mark C. Leake
language : en
Publisher: Springer Nature
Release Date : 2022-05-30
Chromosome Architecture written by Mark C. Leake and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-05-30 with Science categories.
This detailed new edition collects cutting-edge laboratory protocols, techniques, and applications in use by some of the leading international experts in the broad field of chromosome architecture. The book emphasizes the increasing physiological relevance of chromosome architecture investigation, manifest both through application of more complex bottom-up assays in vitro as well as through maintaining the native physiological context through the investigation of living, functional cells. In addition, the chapters reflect the dramatic improvement in the length scale of precision by utilizing single-molecule approaches, both for imaging the DNA content of chromosome and proteins that bind to DNA as well as using methods that can controllably manipulate single DNA molecules, and the use of advanced computational methods and mathematical analysis is also featured. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and up-to-date, Chromosome Architecture: Methods and Protocols, Second Edition is an ideal guide for researchers working in this dynamic area of study.
Prins And Pna Technologies In Chromosomal Investigations
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Author : Franck Pellestor
language : en
Publisher: Nova Publishers
Release Date : 2007
Prins And Pna Technologies In Chromosomal Investigations written by Franck Pellestor and has been published by Nova Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with Science categories.
Book & CD. Advances in molecular biotechnology have greatly improved the sensitivity and the efficiency of methods utilised for genetic investigations and diagnosis. In the domain of chromosome analysis, the introduction of molecular techniques has led to the development of a new approach, called Molecular Cytogenetics, which has surpassed previously available techniques to become a foremost biological method. The fluorescence in situ hybridisation (FISH) is quickly became the standard technique for in situ chromosomal investigations, as illustrated by its large variety of applications in research and diagnosis. However, during the last decade, alternative methods to FISH have been introduced and have shown to be valuable in detecting chromosomes and quantifying chromosomal abnormalities. These alternative procedures are the Primed IN Situ (PRINS) labelling and the Peptide Nucleic Acid (PNA) probes. The two procedures present several advantages for the in situ detection of nucleic acid sequences, such as the small size of PNA probes and PRINS primers, or the fast kinetics of PRINS and PNA labelling reactions, that make them very attractive for a number of cytogenetic purposes. This book provides a valuable introduction and overview of the principles and the applications of alternative approaches in the field of molecular cytogenetics.
Fertility And Chromosome Pairing
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Author : Christopher Bob Gillies
language : en
Publisher: CRC Press
Release Date : 2020-07-24
Fertility And Chromosome Pairing written by Christopher Bob Gillies and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-07-24 with Medical categories.
This book discusses the nature of meiotic chromosome pairing effects which may play a role in the determination of fertility. In particular, data and illustrations from the application of recently developed electron microscopic spreading techniques will allow researchers in related fields to come to grips with the recent advances in the cytogenetics of meiotic chromosome pairing behavior. Topics dealt with include meiotic and synaptonemal complex behavior in humans and mice with a variety of chromosomal and genetic abnormalities, sex chromosome pairing in mammals and birds, the significance for fertility or pairing in mammals and birds, the significance for fertility of XY pairing and crossing over, the effects of hybridity on pairing and fertility in plants, and the genetic control of synaptonemal complex formation and crossing over in polyploids. This is a timely reference book for graduate level medical and veterinary students, and scientists in the field of genetics and cell biology.
New Methods Of Investigating Chromosome Structure
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Author : Samarendra Basu
language : en
Publisher:
Release Date : 1982
New Methods Of Investigating Chromosome Structure written by Samarendra Basu and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1982 with categories.
Genetics
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Author : Thomas Robert Mertens
language : en
Publisher: MacMillan Publishing Company
Release Date : 1991
Genetics written by Thomas Robert Mertens and has been published by MacMillan Publishing Company this book supported file pdf, txt, epub, kindle and other format this book has been release on 1991 with Science categories.
THE definitive genetics lab manual for over 50 years, this user-friendly volume stresses classical genetics, but includes some of the recent advances related to molecular and human genetics as well. Drosophila and Maize Experiments in Genetics: Monohybrid Crosses; Dihybrid Crosses. Cell Reproduction: Mitosis. Meiosis in Animals: Oogenesis and Spermatogenesis. Meiosis in Angiosperms: Microsporogenesis and Megasporogenesis. Polytene Chromosomes from Drosophila Salivary Glands. Sex Chromosomes and Gene Transmission. The Sex Check: A Study of Sex Chromatin in Human Cells. Human Chromosomes. Linkage and Crossing Over. Genetics of Ascospore Color in Sordaria : An Investigation of Linkage and Crossing Over Using Tetrad Analysis. Open-Ended Experiments Using Drosophila : Locating a Mutant Gene in Its Chromosome. Isolation of DNA. Restriction Endonuclease Digestion and Gel Electrophoresis of DNA. Amplification of DNA Polymorphisms by Polymerase Chain Reaction (PCR) and DNA Fingerprinting. Transformation of Escherichia coli. Gene Action: Synthesis of ... b-Galactosidase in Escherichia coli. Chromatographic Characterization of Drosophila melanogaster Mutants. Bacterial Mutagenesis. Gene Recombination in Phage. Polygenic Inheritance: Fingerprint Ridge Count. Population Genetics: The Hardy-Weinberg Principle; The Effects of Selection and Genetic Drift. Applied Human Genetics.
Human Chromosome Atlas
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Author : Claudia Behrend
language : en
Publisher: Springer
Release Date : 2017-07-06
Human Chromosome Atlas written by Claudia Behrend and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-07-06 with Medical categories.
This atlas presents the results of cases of structural chromosome aberrations based on the currently available methods of analysis for different types of abnormality. It particularly focuses on which spectrum should be chosen when combining the different techniques to achieve the best method of diagnosis in individual cases, for example direct preparation of cells and mitoses, short or long-time cell culture, fluorescence in situ hybridization (FISH), analysis of interphases, microarray or DNA sequencing. Generally it has to be taken into account, that the development of new and improved investigation methods is forthcoming. Thus, by improvement of diagnostic possibilities new fields of investigation arise, and special groups of patients with cytogenetic analyses can be re-analysed under new research questions.