Lactobacillus Rhamnosus Lgg
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Lactobacillus Rhamnosus Lgg
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Author : Ulla Holmboe Gondolf
language : en
Publisher:
Release Date : 201?
Lactobacillus Rhamnosus Lgg written by Ulla Holmboe Gondolf and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 201? with categories.
The Science Behind Lactobacillus Rhamnosus Lgg
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Author :
language : en
Publisher:
Release Date :
The Science Behind Lactobacillus Rhamnosus Lgg written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on with categories.
A Promising Biopolymer Based Carrier For Optimal Delivery Of Probiotics Lactobacillus Rhamnosus Gg Lgg
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Author : Maryam Eshrati
language : en
Publisher:
Release Date : 2018
A Promising Biopolymer Based Carrier For Optimal Delivery Of Probiotics Lactobacillus Rhamnosus Gg Lgg written by Maryam Eshrati and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018 with categories.
A Study On The Role Of Probiotic Lactobacillus Rhamnosus Gg On Gastric Mucosal Damages In Rats
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Author : Kai-Yee Lam
language : en
Publisher:
Release Date : 2017-01-27
A Study On The Role Of Probiotic Lactobacillus Rhamnosus Gg On Gastric Mucosal Damages In Rats written by Kai-Yee Lam and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-01-27 with categories.
This dissertation, "A Study on the Role of Probiotic Lactobacillus Rhamnosus GG on Gastric Mucosal Damages in Rats" by Kai-yee, Lam, 林佳儀, was obtained from The University of Hong Kong (Pokfulam, Hong Kong) and is being sold pursuant to Creative Commons: Attribution 3.0 Hong Kong License. The content of this dissertation has not been altered in any way. We have altered the formatting in order to facilitate the ease of printing and reading of the dissertation. All rights not granted by the above license are retained by the author. Abstract: Abstract Abstract of the thesis entitled A study on the role of probiotic Lactobacillus rhamnosus GG on gastric mucosal damages in rats Submitted by Lam Kai-Yee For the degree of Master of Philosophy at the University of Hong Kong In August 2006 The gastrointestinal (GI) tract is colonized by a vast community of microorganisms and maintenance of the microbial balance is essential for gut health. For decades, probiotics have been shown to maintain the GI equilibrium of indigenous microflora. Although numerous studies have advocated their use for the prevention and treatment of various GI disorders, the role of probiotics in gastric mucosal damage has been comparatively neglected. The aim of this study is to investigate the beneficial effects of a probiotic strain Lactobacillus rhamnosus GG (LGG) on acetic acid-induced gastric ulcer and ethanol-induced gastric lesions and to elucidate the mechanisms involved. The study found that LGG significantly and dose-dependently reduced gastric ulcer area. The cell apoptosis to cell proliferation ratio was strongly decreased and accompanied by significant upregulation of ornithine decarboxylase (ODC) and B-cell lymphoma 2 (Bcl-2) protein expressions at the ulcer margin. Angiogenesis was also significantly stimulated together with the induction of vascular endothelial growth factor (VEGF) and cyclooxygenase-2 (COX-2) expression. Furthermore, LGG up-regulated the phosphorylation levels of epidermal growth factor receptor (EGFR) and the downstream extracelluar signal-regulated kinase 1/2 (Erk1/2) iwithout altering total EGFR and Erk1/2 expression. These findings suggest that LGG enhanced gastric ulcer healing via the attenuation of cell apoptosis to cell proliferation ratio and increase in angiogenesis. Regulators of these processes such as ODC, Bcl-2, VEGF, COX-2, EGFR and Erk1/2 are likely to be involved in the ulcer healing action of LGG. LGG pretreatment also significantly reduced ethanol-induced gastric lesions in a dose-dependent manner. This was accompanied by the increase of basal mucosal prostaglandin E (PGE ) level and endothelial nitric oxide synthase (eNOS) protein 2 2 expression. In addition, LGG attenuated the suppressive action of ethanol on mucus layer, mucin 6 (muc6) mRNA expression and transmucosal resistance, and reversed the stimulatory action of ethanol on cellular apoptosis in the gastric mucosa. It is suggested that the protective role of LGG on ethanol-induced gastric mucosal lesions is likely attributable to the upregulation of PGE and eNOS, which in turn, stimulates the mucus secretion to increase the transmucosal resistance and subsequently protects cells from apoptosis in the gastric mucosa. The study's findings indicate the capability of LGG to act as a therapeutic and prophylactic agent in treating and preventing gastric damage. ii DOI: 10.5353/th_b3734005 Subjects: Lactobacillus Gastrointestinal diseases - Animal models
Effect Of Lactobacillus Rhamnosus Gg Lgg And Bifidobacterium Animalis Subspecies Lactis Bb 12 On Health Related Quality Of Life In College Students With Upper Respiratory Infections
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Author : Tracey Jane Smith
language : en
Publisher:
Release Date : 2011
Effect Of Lactobacillus Rhamnosus Gg Lgg And Bifidobacterium Animalis Subspecies Lactis Bb 12 On Health Related Quality Of Life In College Students With Upper Respiratory Infections written by Tracey Jane Smith and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011 with categories.
Coaggregation Patterns And Surface Characteristics Of Lactobacillus Rhamnosus Gg Under Varying Nutrient Conditions
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Author : Roxanne Reinhardt
language : en
Publisher:
Release Date : 2019
Coaggregation Patterns And Surface Characteristics Of Lactobacillus Rhamnosus Gg Under Varying Nutrient Conditions written by Roxanne Reinhardt and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019 with Biofilms categories.
Lactobacillus rhamnosus GG (LGG) is one of the best studied probiotic organisms. The ability of probiotics to adhere to other microorganisms and the intestinal epithelium is thought to play a major role in their protective functions. Coaggregation is an important mechanism for biofilm formation by microorganisms. The goals of this study were to examine the ways in which nutrient variation affects intercellular interactions between LGG and other gut microbes and the hydrophobic character of LGG. We hypothesized that nutritional variation may affect the ability of LGG to coaggregate and form biofilms and thus affect its probiotic characteristics and ability to colonize the gastrointestinal tract. Lactobacil/us rhamnosus GG was cultured anaerobically in different formulations of tryptone, yeast extract, and glucose (TYG) medium in order to simulate a milk-based, plant-based, and meat-based diet. Since the gut is mainly colonized by microorganisms belonging to the Firmicutes and Bacteroidetes phyla, we tested the coaggregation ability between LGG and Bacteroides spp. and ParabacJeroides spp. Our results suggest that coaggregation varies by media type, with LGG cultured in BeYG [Beef extract (meat protein), yeast extract, and glucose] medium exhibiting the highest coaggregation scores. Hydrophobicity values of LGG cells cultured in varying nutrient conditions differed significantly by media type, and LGG cultured in BeYG exhibited the highest hydrophobicity scores. These results indicate that different nutrient conditions may enhance the ability of LGG to colonize the human gut microbiome and enhance its ability to act as a successful probiotic.
Lactobacillus Rhamnosus Gg And Its Lysate Protects Human Epidermal Keratinocytes From The Toxic Effect Of Specific Wound Pathogens
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Author : Muna Alhubail
language : en
Publisher:
Release Date : 2017
Lactobacillus Rhamnosus Gg And Its Lysate Protects Human Epidermal Keratinocytes From The Toxic Effect Of Specific Wound Pathogens written by Muna Alhubail and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017 with categories.
Lactobacillus rhamnosus GG and its lysate protects human epidermal keratinocytes from the toxic effect of specific wound pathogensMuna Alhubail1, Sheena Cruickshank1, Andrew McBain2, Catherine O'Neill11School of Biological Science, 2School of Health SciencesAbstractChronic wounds represent a huge challenge for health care providers. Infection of these wounds further complicates the situation and limits the effectiveness of available treatments necessitating the development of new treatments to eradicate infection and promote healing. The topical use of probiotics may offer new alternatives that are efficient and safe to use. L. rhamnosus GG (LGG) is one of the best studied probiotics. The aim of the study was to assess the effectiveness of both viable LGG and lysate in protecting human epidermal keratinocytes from the toxic effect of wound pathogens such as: Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli, Streptococcus pyogenes and Acinetobacter baumannii. Trypan blue exclusion assay was used to assess the viability of human epidermal keratinocyte after 24 h of incubation with each wound pathogen, and following co-incubation of wound pathogens with viable LGG or with different concentrations of LGG lysate. All the tested pathogens significantly reduced the percentage viability of keratinocytes. Both viable LGG and its lysate significantly increased the viability of keratinocytes when co-incubated with S. aureus and E. coli. However, neither viable LGG nor its lysate induced significant increase in keratinocyte viability when co-incubated with P. aeruginosa, S. pyogenes and A. baumannii. In conclusion, both viable LGG and its lysate may have utility in prevention of wound infection. However, such effects may be restricted to certain pathogens.
Coaggregation Of Gut Bacteroides Parabacteroides With Probiotic Lactobacillus Rhamnosus Gg
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Author : Samuel Schotten
language : en
Publisher:
Release Date : 2016
Coaggregation Of Gut Bacteroides Parabacteroides With Probiotic Lactobacillus Rhamnosus Gg written by Samuel Schotten and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016 with Adhesion categories.
Coaggregation has been indicated as a key mechanism in the formation of biofilms. This research sought to characterize the interactions occurring between native gastrointestinal Bacteroides & Parabacteroides and the probiotic strain Lactobacillus rhamnosus GG (LGG) cultured in Todd Hewitt (TH), deMan, Rogosa, and Sharpe (MRS), and Brain Heart Infusion (BHI) using in vitro coaggregation assays. In the coaggregation survey of interactions, a trend of growth medium-dependent coaggregation variability was displayed with LGG grown in TH displaying the widest spectrum of coaggregation with Bacteroides/Parabacteroides strains and narrower spectrum from the other cultures of LGG. By protease inhibition, it was confirmed that the presence of novel adhesin(s) occurs on LGG, mediating coaggregation with moderate strength to a variety of Bacteroides & Parabacteroides strains abundant in the large intestine, including selective interactions with capsule-deficient mutants of B. thetaiotaomicron VPI-5482. In the case of LGG grown in MRS, bimodal adhesin interaction with involvement of Bacteroides/Parabacteroides partners was observed. These interactions were not reversed by the addition of a variety of simple sugars, providing no support for the presence of a lectin-like adhesion on LGG, and thus the affinity of the adhesin(s) involved remains to be characterized.
The Microbiota In Gastrointestinal Pathophysiology
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Author : Martin H. Floch
language : en
Publisher: Academic Press
Release Date : 2016-11-16
The Microbiota In Gastrointestinal Pathophysiology written by Martin H. Floch and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-11-16 with Science categories.
The Microbiota in Gastrointestinal Pathophysiology: Implications for Human Health, Prebiotics, Probiotics and Dysbiosis is a one-stop reference on the state-of-the-art research on gut microbial ecology in relation to human disease. This important resource starts with an overview of the normal microbiota of the gastrointestinal tract, including the esophagus, stomach, Ileum, and colon. The book then identifies what a healthy vs. unhealthy microbial community looks like, including methods of identification. Also included is insight into which features and contributions the microbiota make that are essential and useful to host physiology, as is information on how to promote appropriate mutualisms and prevent undesirable dysbioses. Through the power of synthesizing what is known by experienced researchers in the field, current gaps are closed, raising understanding of the role of the microbiome and allowing for further research. Explains how to modify the gut microbiota and how the current strategies used to do this produce their effects Explores the gut microbiota as a therapeutic target Provides the synthesis of existing data from both mainstream and non-mainstream sources through experienced researchers in the field Serves as a ‘one-stop’ shop for a topic that’s currently spread across a number of various journals
Application Of Disaccharides Pre Treatment In Improving Tolerances Of Lactobacillus Rhamnosus Strains To Environmental Stresses Or During Vacuum And Spray Drying Processes
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Author : Elizabeth Sunny-Roberts
language : en
Publisher: Cuvillier Verlag
Release Date : 2009-12-04
Application Of Disaccharides Pre Treatment In Improving Tolerances Of Lactobacillus Rhamnosus Strains To Environmental Stresses Or During Vacuum And Spray Drying Processes written by Elizabeth Sunny-Roberts and has been published by Cuvillier Verlag this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-12-04 with Science categories.