Lideran A E Prop Sito
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Translational Medicine
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Author : Joy A. Cavagnaro
language : en
Publisher: CRC Press
Release Date : 2021-11-26
Translational Medicine written by Joy A. Cavagnaro and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-26 with Medical categories.
Translational Medicine: Optimizing Preclinical Safety Evaluation of Biopharmaceuticals provides scientists responsible for the translation of novel biopharmaceuticals into clinical trials with a better understanding of how to navigate the obstacles that keep innovative medical research discoveries from becoming new therapies or even making it to clinical trials. The book includes sections on protein-based therapeutics, modified proteins, oligonucleotide-based therapies, monoclonal antibodies, antibody–drug conjugates, gene and cell-based therapies, gene-modified cell-based therapies, combination products, and therapeutic vaccines. Best practices are defined for efficient discovery research to facilitate a science-based, efficient, and predictive preclinical development program to ensure clinical efficacy and safety. Key Features: Defines best practices for leveraging of discovery research to facilitate a development program Includes general principles, animal models, biomarkers, preclinical toxicology testing paradigms, and practical applications Discusses rare diseases Discusses "What-Why-When-How" highlighting different considerations based upon product attributes. Includes special considerations for rare diseases About the Editors Joy A. Cavagnaro is an internationally recognized expert in preclinical development and regulatory strategy with an emphasis on genetic medicines.. Her 40-year career spans academia, government (FDA), and the CRO and biotech industries. She was awarded the 2019 Arnold J Lehman Award from the Society of Toxicology for introducing the concept of science-based, case-by-case approach to preclinical safety evaluation, which became the foundation of ICH S6. She currently serves on scientific advisory boards for advocacy groups and companies and consults and lectures in the area of preclinical development of novel therapies. Mary Ellen Cosenza is a regulatory toxicology consultant with over 30 years of senior leadership experience in the biopharmaceutical industry in the U.S., Europe, and emerging markets. She has held leadership position in both the American College of Toxicology (ACT) and the International Union of Toxicology (IUTOX) and is also an adjunct assistant professor at the University of Southern California where she teaches graduate-level courses in toxicology and regulation of biologics.
Global Corruption Report Sport
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Author : Transparency International
language : en
Publisher: Routledge
Release Date : 2016-02-05
Global Corruption Report Sport written by Transparency International and has been published by Routledge this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-02-05 with Business & Economics categories.
Sport is a global phenomenon engaging billions of people and generating annual revenues of more than US$ 145 billion. Problems in the governance of sports organisations, fixing of matches and staging of major sporting events have spurred action on many fronts. Yet attempts to stop corruption in sport are still at an early stage. The Global Corruption Report (GCR) on sport is the most comprehensive analysis of sports corruption to date. It consists of more than 60 contributions from leading experts in the fields of corruption and sport, from sports organisations, governments, multilateral institutions, sponsors, athletes, supporters, academia and the wider anti-corruption movement. This GCR provides essential analysis for understanding the corruption risks in sport, focusing on sports governance, the business of sport, planning of major events, and match-fixing. It highlights the significant work that has already been done and presents new approaches to strengthening integrity in sport. In addition to measuring transparency and accountability, the GCR gives priority to participation, from sponsors to athletes to supporters an essential to restoring trust in sport.
The One And Only Sparkella
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Author : Channing Tatum
language : en
Publisher: Feiwel & Friends
Release Date : 2021-05-04
The One And Only Sparkella written by Channing Tatum and has been published by Feiwel & Friends this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-05-04 with Juvenile Fiction categories.
An Instant #1 New York Times Bestseller! A Publishers Weekly Bestseller! Leading actor, producer and director Channing Tatum's picture book debut, The One and Only Sparkella is a charming ode to self-esteem and the love between a father and daughter—illustrated by Kim Barnes. Ella is excited for her first day at a new school. Glimmering pencil case? Check! Shimmering backpack? Check! Glittery ribbons in her hair? Check! She can't wait to meet the other kids and share her sparkly personality. But her first day doesn't go quite as planned: Her new classmates don't like her disco-ball shoes, her PB&J-with-sprinkles sandwich, or her rainbow-y unicorn painting. Ella decides to try to be less sparkly at school the next day so the other kids won't make fun of her. But with a little help from her dad, she soon learns the importance of just being herself, no matter what other people say.
Radical Markets
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Author : Eric A. Posner
language : en
Publisher: Princeton University Press
Release Date : 2019-10-08
Radical Markets written by Eric A. Posner and has been published by Princeton University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-10-08 with Business & Economics categories.
Revolutionary ideas on how to use markets to achieve fairness and prosperity for all Many blame today's economic inequality, stagnation, and political instability on the free market. The solution is to rein in the market, right? Radical Markets turns this thinking on its head. With a new foreword by Ethereum creator Vitalik Buterin and virtual reality pioneer Jaron Lanier as well as a new afterword by Eric Posner and Glen Weyl, this provocative book reveals bold new ways to organize markets for the good of everyone. It shows how the emancipatory force of genuinely open, free, and competitive markets can reawaken the dormant nineteenth-century spirit of liberal reform and lead to greater equality, prosperity, and cooperation. Only by radically expanding the scope of markets can we reduce inequality, restore robust economic growth, and resolve political conflicts. But to do that, we must replace our most sacred institutions with truly free and open competition—Radical Markets shows how.
The Orange Juice Business
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Author : Marcos Fava Neves
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-04-07
The Orange Juice Business written by Marcos Fava Neves and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-04-07 with Science categories.
The orange juice chain is unique, probably a sui generis commodity. Although several countries produce oranges and juices, two regions in the world are the responsible for around 80% of the production. These are the states of Sao Paulo in Brazil and Florida in the USA. Although the emerging countries are growing in production, the juice consumer is also concentrated in the USA and Europe where more than 90% of consumption takes place. The characteristics of this chain are so unique, that it makes a nice laboratory for academics and business people to exercise strategies, since risk is spread. Orange is a very sensitive plant, and fluctuations in production are notorious. The logistics of this chain are fascinating. The product travels great distances to reach the consumer in a generally safe and efficient way. The industry assets such as vessels and tanks are specific. By reading this book, business people, academics and chain practitioners have an opportunity to understand this chain. and can analyse all of its numbers and economics and exercise strategy building. This is needed since the orange juice market is a stable market in the world, growing only 1% per year, and the production costs of this chain are rising fast, due to structural changes faced by world food and agribusiness companies i.e. labour costs, energy costs, land costs, environmental costs and others. The book will be of interest to all those concerned with agri food chains.
The Situational Leader
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Author : Paul Hersey
language : en
Publisher:
Release Date : 1997
The Situational Leader written by Paul Hersey and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997 with Executive ability categories.
For organizations to achieve excellence in today's world, the commitment to develop people is becoming increasingly important. It is the effective utilization of the human resources that is the cornerstone to high performing organizations. This book presents a practical framework to developing people and increasing productivity.
Marketing Destinations And Venues For Conferences Conventions And Business Events
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Author : Rob Davidson
language : en
Publisher: Routledge
Release Date : 2012-05-31
Marketing Destinations And Venues For Conferences Conventions And Business Events written by Rob Davidson and has been published by Routledge this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-05-31 with Business & Economics categories.
Marketing Destinations and Venues for Conferences, Conventions and Business Events covers key areas in marketing and promotion, such as: * Trends and issues in destination and venue marketing * Strategic marketing planning, ROI and strategy evaluation * Destination and venue selling strategies * Future challenges, opportunities and supply-side developments
Transformational And Charismatic Leadership
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Author : Bruce J. Avolio
language : en
Publisher: Emerald Group Publishing
Release Date : 2013-06-25
Transformational And Charismatic Leadership written by Bruce J. Avolio and has been published by Emerald Group Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-25 with Business & Economics categories.
This is the 10th anniversary edition, we seek to update the theoretical and empirical work and professional practice issues associated with transformational and charismatic leadership that have transpired over the past decade.
Smes In An Era Of Globalization
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Author : Ilan Bijaoui
language : en
Publisher: Springer
Release Date : 2016-11-24
Smes In An Era Of Globalization written by Ilan Bijaoui and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-11-24 with Business & Economics categories.
This book identifies the driving forces behind globalization and proposes innovative ways for small and medium-enterprises (SMEs) to confront them. More than ever, sustainable competitive advantage requires SMEs to continually adapt their strategy and confront new and current competition in the international market. SMEs working with multinational companies could also benefit from winning strategies based on a sensible analysis of rational and irrational phenomena at the micro- and macro-economic levels. This book uses different models developed and established through international business experiences to determine the relevant strategy in the global market. It illustrates each model through real, successful case studies of globalization of factor, efficiency, and innovation-driven SMEs. It will benefit scholars of entrepreneurship, international business, regional development as well as managers, governmental institutions, and regional development, and consultants to SMEs.
The Sales Development Playbook
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Author : Trish Bertuzzi
language : en
Publisher:
Release Date : 2016
The Sales Development Playbook written by Trish Bertuzzi and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016 with Sales management categories.
A book to help companies find customers and create repeatable sales by developing effective inside sales organizations and development strategies.