Lymphocyte Activation And Immune Regulation Ix
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Lymphocyte Activation And Immune Regulation Ix
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Author : Sudhir Gupta
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Lymphocyte Activation And Immune Regulation Ix written by Sudhir Gupta and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
This volume is divided into three sections. Section I deals with factors that regulate the development and maturation of T cells and B cells and lymphocyte traffic. The significance of C-kit, Bcl-6, IL-7, and Vav in the development of T and B lymphocytes is discussed. A role of lymphotoxins and VAP-I in trafficking of leucocytes is reviewed. Finally, the trafficking and homing characteristics of T cell and B cell subsets, and the regulation of these processes during the immune response, is presented. Section II discusses various aspects of naive and memory T cell biology, including clonal expansion, reprogramming of genes including those encoding cytokines and cytotoxic granules, changes in the expression of cell surface proteins involved in cell-cell adhesion, homing of naive and memory T cells, the role of MHC and cytokines in the maintenance of naive and memory T cells, and the characterization and differentiation of virus-specific memory T cell heterogeneity in mice and humans. Novel methods of visualization of immune cells and immune systems are reviewed in Section III.
Mechanisms Of Lymphocyte Activation And Immune Regulation Ii
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Author : S. Gupta
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-06-29
Mechanisms Of Lymphocyte Activation And Immune Regulation Ii written by S. Gupta and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-29 with Medical categories.
The ac ti vati on of Iymphocytes by physiologie ligands has become a central area of study for immunologists. Furthermore, Iymphocytes offer many advantages for the study of general aspects of receptor-mediated cellular activation. For these reasons, research on the cellular and molecular aspects of the activation of Iymphocytes by antigens, antigen analogues, Iymphokines and other growth factors has expanded enormously in the last several years. Aseries of conferences, "The International Conferences on Lymphocyte Activation", has been initiated to meet the growing need for a forum for the discussion of the topics that are included within the area of Iymphocyte activation. This volume represents the proceedings of the Second International Conference on Lymphocyte Activation and Immune Regulation, held on February 18-20, 1988 at Newport Beach, California. The proceedings comprise four major sections. The first deals with the T cell receptors and T cell activation. It includes a model for the T cell receptor interaction with a complex of MHC plus antigen, structure of y c'i T cell receptor and their distinct isotypic forms, the role of zeta chain in the expression and structure of T cell receptors and its role in transmembrane signalling. The use of somatic cell mutants in the study of signal transduction function of the T cell antigen receptors and the early and late steps of signal transduction via a / ß T cell antigen receptors are discussed.
Mechanisms Of Lymphocyte Activation And Immune Regulation X
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Author :
language : en
Publisher:
Release Date : 2005
Mechanisms Of Lymphocyte Activation And Immune Regulation X written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with categories.
Mechanisms Of Lymphocyte Activation And Immune Regulation Iii
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Author : Sudhir Gupta
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Mechanisms Of Lymphocyte Activation And Immune Regulation Iii written by Sudhir Gupta and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Recent advances in the understanding of the major events that shape the immune recog nition system have been remarkable. The analysis of immunoglobulin (Ig) gene organization and Ig repertoire diversification in lower vertebrates has provided new insight into this process in mammals. Similarly, the understanding of the early development of lymphocytes and of the acquisition of immunological tolerance has been aided by elegant studies in quail/chicken chimeras, using the power of the distinctive markers of the constitutive cells of these birds. Great strides have been made in understanding the role played by major histocompatibility complex (MHC) molecules in antigen presentation and in repertoire selec tion within the thymus. The use of transgenic mice expressing specific T-cell receptor (TCR) genes has elucidated the process of both positive and negative selection. In parallel, there has been considerable progress in our understanding of tolerance, based in part on the use of markers for the V fJ genes of T-cell receptors and in part on the analysis of the behavior of long term T-cell lines. This has led to the realization that both clonal deletion and clonal anergy may play critical roles in the maintenance of unresponsiveness to self antigen. Molecular analysis of the requirements for expression of membrane immunoglobulin molecules has revealed the existence of a complex that appears to be of critical importance in mediating signalling through Ig receptors. In addition, major insights have been obtained into the regulation of expression of genes of immunologic interest.
Mechanisms Of Lymphocyte Activation And Immune Regulation
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language : en
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Mechanisms Of Lymphocyte Activation And Immune Regulation written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on with categories.
Lymphocyte Activation And Immune Regulation
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Author :
language : en
Publisher:
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Lymphocyte Activation And Immune Regulation written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on with categories.
Mechanisms Of Lymphocyte Activation And Immune Regulation X
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Author : Sudhir Gupta
language : en
Publisher: Springer
Release Date : 2010-12-01
Mechanisms Of Lymphocyte Activation And Immune Regulation X written by Sudhir Gupta and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-12-01 with Medical categories.
This volume is edited by Dr. Sudhir Gupta, internationally recognized expert in Immunology, Professor of Medicine, Pathology, Microbiology and Molecular Genetics. Topics include toll receptors, dendritic cells, NK cells, and complement receptors.
Mechanisms Of Lymphocyte Activation And Immune Regulation
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Author : Sudhir Gupta
language : en
Publisher: Springer
Release Date : 2012-12-27
Mechanisms Of Lymphocyte Activation And Immune Regulation written by Sudhir Gupta and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-27 with Science categories.
During the past 5 years rapid progress has been made in the understanding of biochemical pathways for signal transduction in lymphocyte activation. Gene cloning technology has been instrumental in defining and making available in pure form of a number of growth and differentiation factors, in the characterization of their receptors, and in the delineation of genes for the T cell receptor. This book is divided into 6 sections. Section 1 deals with the molecular structure of the T cell receptor. Section 2 discusses the role of the T cell receptor, membrane ion channels and biochemical pathways of signal transduction in T cell activation. The molecular structures and biological and immunological effects of interleukin 1, interleukin 2 and interleukin 3 are presented in Section 3. This section also details the structure of interleukin 2 receptor and its use as a target for therapy for certain leukemias. Section 4 includes the biochemical events which occur following the delivery of the signal for B cell activation, proliferation, and differentiation by antigen, growth/differentiation factors. The molecular structure of B cell stimulating factors is also discussed. The role of oncogene expression in cellular activation and differentiation is included in Section 5. The cellular and molecular basis of natural killing and the molecular basis of cyc1osporin A-mediated immunosuppression are discussed in detail in Section 6. We hope this book will serve as a reference work on basic mechanisms of lymphocyte activation, proliferation, and differentiation for immunologists and molecular biologists.
Mechanisms Of Lymphocyte Activation And Immune Regulation Iv
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Author : Sudhir Gupta
language : en
Publisher: Springer Science & Business Media
Release Date : 1992
Mechanisms Of Lymphocyte Activation And Immune Regulation Iv written by Sudhir Gupta and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992 with Medical categories.
In 23 papers from an international conference in Newport Beach, California, February 1992, immunologists and molecular biologists focus on the role interactions among the cells play in lymphocyte activation and immune regulation. The general topics are cell receptors and T-cell activation; T-cell de
Mechanisms Of Lymphocyte Activation And Immune Regulation Iv
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Author : Sudhir Gupta
language : en
Publisher:
Release Date : 1992
Mechanisms Of Lymphocyte Activation And Immune Regulation Iv written by Sudhir Gupta and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992 with Cellular signal transduction categories.