Macrocycles

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Macrocycles In Drug Discovery

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Author : Jeremy I Levin
language : en
Publisher: Royal Society of Chemistry
Release Date : 2015

Macrocycles In Drug Discovery written by Jeremy I Levin and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015 with Medical categories.

This series provides a comprehensive resource for postgraduate students and for scientists in academia or industry wanting to learn topics outside their own areas of expertise.

Practical Medicinal Chemistry With Macrocycles

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Author : Eric Marsault
language : en
Publisher: John Wiley & Sons
Release Date : 2017-09-12

Practical Medicinal Chemistry With Macrocycles written by Eric Marsault and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-09-12 with Science categories.

Including case studies of macrocyclic marketed drugs and macrocycles in drug development, this book helps medicinal chemists deal with the synthetic and conceptual challenges of macrocycles in drug discovery efforts. Provides needed background to build a program in macrocycle drug discovery –design criteria, macrocycle profiles, applications, and limitations Features chapters contributed from leading international figures involved in macrocyclic drug discovery efforts Covers design criteria, typical profile of current macrocycles, applications, and limitations

Cation Binding By Macrocycles

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Author : Inoue
language : en
Publisher: Routledge
Release Date : 2018-10-03

Cation Binding By Macrocycles written by Inoue and has been published by Routledge this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-10-03 with Medical categories.

This reference details the theory and application of cation complexation, including the design and synthesis of various cyclic systems, these materials' use as transport systems, in complexation and selectivity studies by macrocyclic systems, and methodologies for understanding these phenomena. In a

N4 Macrocyclic Metal Complexes

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Author : J.H. Zagal
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-07-16

N4 Macrocyclic Metal Complexes written by J.H. Zagal and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-07-16 with Science categories.

In response to significant developments in sensor science and technology, this book offers insight into the various extended applications and developments of N4 macrocycle complexes in biomimetic electrocatalysis. Chapters are devoted to the chemistry, electronic and electrochemical properties of porphyrin- based polymetallated supramolecular redox catalysts and their applications in analytical and photoelectrochemical molecular devices; the use of porphyrins, phthalocyanines and related complexes as electrocatalysts for the detection of a wide variety of environmentally polluting and biologically relevant molecules; and the use of electropolymerized metalloporphyrin and metallophthalocyanine films as powerful materials for analytical tools, especially for sensing biologically relevant species.

Stereochemical And Stereophysical Behaviour Of Macrocycles

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Author : Bozzano G Luisa
language : en
Publisher: Elsevier
Release Date : 2012-12-02

Stereochemical And Stereophysical Behaviour Of Macrocycles written by Bozzano G Luisa and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Science categories.

Stereochemical and Stereophysical Behavior of Macrocycles deals with the stereochemical and stereophysical properties of macrocyclic ligands and their coordination compounds. More specifically, the stereochemistry of metallic macrocyclics is discussed, along with the relationship between the thermodynamics and stereochemistry of macrocyclics and cryptates. The stereochemical aspects of the macrocycles of second and third row transition elements are also examined. Comprised of three chapters, this volume begins with an introduction to the stereochemistry of metallic macrocyclics as well as their structure, together with the conformation of their chemical rings and the steric effects of their coordination geometry. The next chapter considers the relationship between the thermodynamics and stereochemistry of macrocyclics and cryptates, with particular reference to the macrocyclic and cryptate effect. Cation-ligand interactions and solvent effects upon complex formation are described, along with macrocyclic and macrobicyclic ligands having different donor atoms. The final chapter is devoted to the stereochemical aspects of the macrocycles of transition metal ions, with additional comments on the stereochemistry of copper and nickel in unusual oxidation states. This book will be of interest to inorganic chemists.

Macrocyclic Chemistry

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Author : K. Gloe
language : en
Publisher: Springer Science & Business Media
Release Date : 2005-12-05

Macrocyclic Chemistry written by K. Gloe and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-12-05 with Science categories.

Macrocyclic Chemistry: Current Trends and Future Perspectives illustrates essential concepts in this expanding research field covering both basic and applied studies. Written by well-known experts from around the world, the topics of the chapters range from new macrocyclic architectures with different functions and self-assembly processes through to the modeling and dynamics of such systems. The content also reflects on application possibilities in analytical chemistry, separation processes, material preparation and medicine. Thus this book serves as a creative source of research strategies and methodic tools. Providing an excellent overview of the field, this book will be a valuable resource for researchers in industry and academic institutions as well as for teachers of science and graduate students. This book is devoted to the long-standing tradition of the International Symposia on Macrocyclic Chemistry (ISMC) and published to coincide with the 30th meeting, Dresden, Germany.

Macrocyclic Magic The Enchanted Rings Of Analytical Chemistry

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Author : Pasquale De Marco
language : en
Publisher: Pasquale De Marco
Release Date : 2025-03-09

Macrocyclic Magic The Enchanted Rings Of Analytical Chemistry written by Pasquale De Marco and has been published by Pasquale De Marco this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-03-09 with Science categories.

Embark on an enchanting journey into the realm of macrocyclic chemistry, where molecules with captivating crown-like structures unlock a world of analytical possibilities. "Macrocyclic Magic: The Enchanted Rings of Analytical Chemistry" unveils the secrets of these remarkable compounds, revealing their unique properties and diverse applications that span a multitude of fields. Within the pages of this book, you'll discover the enchanting world of macrocycles, unraveling their intricate mechanisms of action and exploring their remarkable ability to selectively bind and interact with specific analytes. Witness the power of macrocycles as they revolutionize analytical chemistry, enabling highly sensitive and selective sensing, detection, and separation techniques that push the boundaries of analytical science. Delve into the fascinating applications of macrocycles in environmental chemistry, where they emerge as guardians of our planet, offering eco-friendly solutions for the remediation of pollutants and contaminants. Discover how macrocycles can transform the pharmaceutical landscape, serving as the foundation for novel therapeutic agents with enhanced efficacy and reduced side effects, targeting specific biological molecules with precision. Beyond their analytical and environmental prowess, macrocycles have captivated the attention of researchers in materials science, catalysis, and energy storage. Their unique properties inspire the creation of advanced materials with tailored properties, efficient catalysts for diverse chemical reactions, and innovative energy storage systems that promise to shape a sustainable future. "Macrocyclic Magic: The Enchanted Rings of Analytical Chemistry" is an enthralling journey into the realm of these molecular marvels, where the boundaries of chemistry are constantly pushed and new discoveries await. This comprehensive guide is an indispensable resource for chemists, environmental scientists, materials scientists, and anyone seeking to unravel the mysteries of macrocyclic chemistry. If you like this book, write a review!

Aza Crown Macrocycles

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Author : Jerald S. Bradshaw
language : en
Publisher: John Wiley & Sons
Release Date : 2009-09-17

Aza Crown Macrocycles written by Jerald S. Bradshaw and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-09-17 with Science categories.

The Chemistry of Heterocyclic Compounds, since its inception, has been recognized as a cornerstone of heterocyclic chemistry. Each volume attempts to discuss all aspects – properties, synthesis, reactions, physiological and industrial significance – of a specific ring system. To keep the series up-to-date, supplementary volumes covering the recent literature on each individual ring system have been published. Many ring systems (such as pyridines and oxazoles) are treated in distinct books, each consisting of separate volumes or parts dealing with different individual topics. With all authors are recognized authorities, the Chemistry of Heterocyclic Chemistry is considered worldwide as the indispensable resource for organic, bioorganic, and medicinal chemists.

Coordination Chemistry Of Macrocyclic Compounds

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Author : Gordon Melson
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Coordination Chemistry Of Macrocyclic Compounds written by Gordon Melson and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.

Chemists have been aware of the existence of coordination compounds con taining organic macrocyclic ligands since the first part of this century ; however, only during the past few years have they expanded research into the chemistry of these compounds. The expansion was initiated in the early 1960s by the synthesis and characterization of compounds containing some new macrocyclic ligands. The synthesis of compounds which may serve as model systems for some natural products containing large rings as ligands provided the main goal for the early expansion of research effort; indeed, a recurrent theme behind much of the reported chemistry has been the analogy between synthetic macrocyclic compounds and many natural-product systems. More recently, the emphases of reported research have ranged over the whole spectrum of chemistry, and the number of publications that discuss macrocyclic chemistry has increased at a dramatic rate. The completed research has been reported in a variety of journals throughout the world but there has been no previous attempt to bring the major developments together under one cover. This book, therefore, attempts to satisfy the need for a single source in which there is both a collection and a correlation of information concerning the coordination chemistry of macrocyclic compounds. The chapters in this book discuss various aspects of macrocyclic chemistry, and while these chapters as a whole constitute an in-depth survey of the state-of the-art of the field, each chapter is written as a complete unit.

Macrocyclic Polyamines

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Author : Xiaoqi Yu
language : en
Publisher: John Wiley & Sons
Release Date : 2018-02-20

Macrocyclic Polyamines written by Xiaoqi Yu and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-02-20 with Science categories.

The first comprehensive book focusing on synthesis and applications of macrocyclic polyamines and their derivatives Macrocyclic polyamines are a class of widely used important compounds. This is the first book that systematically summarizes the synthesis and applications of macrocyclic polyamines and their analogues, including the properties and synthetic methods of macrocyclic polyamines, chemical nucleases based on macrocyclic polyamines, the derivatives of macrocyclic polyamines as nano-vector materials, macrocyclic polyamines derivatives for bio-imaging, chemical sensors based on macrocyclic polyamines, and other applications of macrocyclic polyamines. Macrocyclic Polyamines: Synthesis and Applications includes most of the studies involving macrocyclic polyamines and their derivatives, and may be used as a reference for the researchers in related fields. It offers in-depth coverage of cyclization modes; special procedures for tetraza macrocyclic compounds; diacids-diamines condensation; oxidative DNA cleaving by macrocyclic polyamines; lipids with cationic MPA headgroups; the derivatives of DOTA, DO3A, and PCTA; receptors for anions; sensors for bioactive molecules; macrocyclic polyamines for solvent extraction and membrane transport of amino acids and their derivatives, electrophoretic separation, and open-tubular CEC; and much more. ?The first book that systematically summarizes the chemistry of macrocyclic polyamines and their derivatives in terms of synthetic methods for their preparation, functionalization, and application in the main fields of chemical sensors, chemical nucleases, drug-delivery, bio-imaging and vector materials ?Provides a comprehensive reference for the researchers working on macrocyclic polyamines ?Offers train of thought in related research fields such as organic chemistry, coordination chemistry, analytical chemistry, supramolecular chemistry, biomaterials, etc. Macrocyclic Polyamines: Synthesis and Applications will not only provide a reference for the researchers working on macrocyclic polyamines, but also offer opportunities for researchers in related research fields to understand the benefits of these key compounds.