Mast Cells Mediators And Disease
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Mast Cells Mediators And Disease
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Author : Stephen T. Holgate
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Mast Cells Mediators And Disease written by Stephen T. Holgate and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
In 1879 Paul Ehrlich first described the mast cell as a tissue fixed cell contain ing many granules which, when stained with basic dyes, such as toluidine blue, changed the colour spectrum of the dye in a process called meta chromasia. Since this early description, pathologists, physicians and pharmacologists have been fascinated by this cell on account of its central involvement in human allergic diseases. Approximately four decades after Ehrlich's first description of the mast cell, Prausnitz and Kiistner reported their pioneer experiment, demonstrating that the immediate skin wheal response to allergen could be passively transferred with serum. They named the antigen-specific serum factor reagin. A further four and one half decades had to pass before the connection between the mast cell and reagin could be made with the identification of reagin as an immunoglobulin E by Johansson and Ishizaka and its unique property to bind with high affinity to specific receptors on mast cells and basophils. Meanwhile in the 1920s Coca published a series of papers in which he described the clinical features of acute allergic responses and first used the term atopy. This, together with the fundamental pharmacological studies of Sir Henry Dale in identifying histamine as one mediator of the acute ana phylactic reaction, provided the second approach which eventually linked the mast cell to allergic tissue reactions. Indeed, it was Best, working in Dale's group who first showed that histamine was a chemical stored in mast cells.
Mast Cells Mediators And Disease
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Author : Stephen T Holgate
language : en
Publisher:
Release Date : 1988-09-30
Mast Cells Mediators And Disease written by Stephen T Holgate and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1988-09-30 with categories.
Mast Cells
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Author : Guha Krishnaswamy
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-02-04
Mast Cells written by Guha Krishnaswamy and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-02-04 with Medical categories.
A cutting-edge collection of readily reproducible techniques for the isolation, culture, and study of activation and signaling in human mast cells. These methods take advantage of the latest advances in molecular biology, technology, and information science. They include methods for the identification of mast cells, the development of mast cells in vitro, the study of mast cell signaling and gene expression, and the measurement of mast cell expression of inflammatory mediators. Additional chapters cover methods for studying mast cell interactions with other cell types (endothelial cells, fibroblasts, and B cells), the roles of mast cells in host defense, and mast cell apoptosis.
Mast Cell Biology
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Author : Alasdair M. Gilfillan
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-06-28
Mast Cell Biology written by Alasdair M. Gilfillan and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-06-28 with Medical categories.
The editors of Mast Cell Biology, Drs. Gilfillan and Metcalfe, have enlisted an outstanding group of investigators to discuss the emerging concepts in mast cell biology with respect to development of these cells, their homeostasis, their activation, as well as their roles in maintaining health on the one hand and on the other, their participation in disease.
The Mast Cell Activation Syndrome Manual
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Author : June Corder
language : en
Publisher:
Release Date : 2021-08-10
The Mast Cell Activation Syndrome Manual written by June Corder and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-08-10 with categories.
Mast cells are allergy cells responsible for immediate allergic reactions. They cause allergic symptoms by releasing products called "mediators" stored inside them or made by them. In allergic reactions, this release occurs when the allergy antibody, which is present on the mast cell surfaces, binds to proteins that cause allergies, called allergens. This triggering is called activation, and the release of these mediators is called degranulation. Some of these mediators are stored in granules in the mast cells and are released quickly and others are made slowly only after the cell has been triggered. Mast cells can also be activated by other substances, such as medications, infections, insect or reptile venoms. These responses, while not desirable, are made by "normal" mast cells. They are called "secondary activation" because they are due to (secondary to) external stimuli. Sometimes mast cells become defective and release mediators because of abnormal internal signals. Certain mutations in mast cells can produce populations of identical mast cells - called clones - that overproduce and spontaneously release mediators. The spontaneous production of mediators in these clonal mast cell disorders is called "primary activation". These abnormal cells can grow uncontrollably and are unusually sensitive to activation in a condition called mastocytosis. This guide will show you the symptoms of MCAS as well as drugs to take, supplements, and natural treatment to end MCAS GET YOUR COPY TODAY BY SCROLLING UP AND CLICKING BUY NOW TO GET YOUR COPY TODAY
Mast Cells In Allergic Diseases
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Author : Hirohisa Saito
language : en
Publisher: Karger Medical and Scientific Publishers
Release Date : 2005-01-01
Mast Cells In Allergic Diseases written by Hirohisa Saito and has been published by Karger Medical and Scientific Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-01-01 with Medical categories.
In this book, the editors have focused on the roles of mast cells in allergic diseases and discuss the future direction of discovering drugs. Another implication of this book is to understand mast cells at the system level. System biology is a research category to understand biology at the system level by examining the structure and dynamics of cellular and organismal functions, rather than the characteristics of isolated parts of a cell or organism.
Mast Cells And Basophils
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Author : Derek J. Chadwick
language : en
Publisher: John Wiley & Sons
Release Date : 2006-01-04
Mast Cells And Basophils written by Derek J. Chadwick and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-01-04 with Medical categories.
The book presents recent advances relating to the factors and mechanisms that regulate the growth, differentiation and function of mast cells and basophils; discussion of new technologies used to study these cells, and integration of the basic scientific findings in the context of therapeutic possibilities for the treatment of diseases such as allergic inflammation and autoimmune disease which are mediated, in part, by these granulocytes.
The Mast Cell In Health And Disease
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Author : Kaliner
language : en
Publisher: CRC Press
Release Date : 1992-10-29
The Mast Cell In Health And Disease written by Kaliner and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992-10-29 with Medical categories.
Offers coverage of practical and theoretical implications of current research into mast cell biology, emphasizing the role of the mast cell in human diseases. The text covers all aspects of the mast cell from growth and differentiation to its function in such conditions as asthma and skin disease.
Mast Cell Disorders An Issue Of Immunology And Allergy Clinics Of North America E Book
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Author : Cem Akin
language : en
Publisher: Elsevier Health Sciences
Release Date : 2023-09-30
Mast Cell Disorders An Issue Of Immunology And Allergy Clinics Of North America E Book written by Cem Akin and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-09-30 with Medical categories.
In this issue of Immunology & Allergy Clinics, guest editor Dr. Cem Akin brings his considerable expertise to the topic of Mast Cell Disorders. Top experts in the field provide readers with information on the identification, management, and treatment of mast cell disorders and mastocytosis. Contains 9 relevant, practice-oriented topics including drug and venom allergy in mastocytosis; quality of life in mastocytosis; effect of gender and special considerations for women in mastocytosis and anaphylaxis; management of mediator symptoms, allergy, and anaphylaxis in mastocytosis; and more. Provides in-depth clinical reviews on mast cell disorders, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.
Mastocytosis An Issue Of Immunology And Allergy Clinics Of North America E Book
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Author : Mariana Castells
language : en
Publisher: Elsevier Health Sciences
Release Date : 2018-07-20
Mastocytosis An Issue Of Immunology And Allergy Clinics Of North America E Book written by Mariana Castells and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-07-20 with Medical categories.
This issue of Immunology and Allergy Clinics, guest edited by Mariana C. Castells, MD, is devoted to Mastocytosis. Articles in this issue include: New Insight into Clonal Mast Cell Disorders Including Mastocytosis; Cutaneous Mastocytosis in Adults and Children: New Classification and Prognostic Factors; Hymenoptera Anaphylaxis as a Clonal Mast Cell Disorder; Non Clonal Mast Cell Activation Syndrome: A growing body of evidence; Familial Tryptasemia Syndromes: Genotyping and Symptoms; POTS and EDS: Entities Associated to Mast Cell Activation; KIT Mutations: New Insight and Diagnostic Value; Patients’ Perceptions in Mast Cell Activation Disorders; Mast Cell Mediators of Significance in Clinical Practice; Tyrosine Kinase Inhibition in Mast Cell Activation Disorders; Gastrointestinal Involvement in Mast Cell Activation Disorders; Bone Marrow Expression of Mast Cell Disorders; Genomics and Proteonomics in Clonal Mast Cell Disorders; and Pediatric Expression of Mast Cell Activation Disorders.
