Measuring Cell Mechanics
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Measuring Cell Mechanics
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Author : Margaret Gardel
language : en
Publisher: Biota Publishing
Release Date : 2015-09-01
Measuring Cell Mechanics written by Margaret Gardel and has been published by Biota Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-09-01 with Science categories.
Cells are inherently physical entities that both experience mechanical forces from their external environment and generate their own internal forces to drive cell motion. Our particular aim here is to present the reader with an introduction to the primary tools used to measure these mechanical interactions and the material properties of cells that result from them. These approaches can be applied to a diverse array of physiological processes and systems, providing important insight into the regulatory roles of mechanical interactions in cells. We cover techniques at both the molecular and cellular scales, including those that actively and passively probe the system. Along the way we cover the fundamental principles of each approach, while emphasizing the relevant length and timescales, along with the typical magnitudes of the measurements that can be made. Each section ends by highlighting uses of the various techniques in recent relevant publications, illustrating the exciting future of cell mechanics in quantitative cell biology research.
Cytoskeletal Mechanics
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Author : Mohammad R. K. Mofrad
language : en
Publisher: Cambridge University Press
Release Date : 2006-09-04
Cytoskeletal Mechanics written by Mohammad R. K. Mofrad and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-09-04 with Science categories.
This book presents a full spectrum of views on current approaches to modeling cell mechanics. The authors come from the biophysics, bioengineering and physical chemistry communities and each joins the discussion with a unique perspective on biological systems. Consequently, the approaches range from finite element methods commonly used in continuum mechanics to models of the cytoskeleton as a cross-linked polymer network to models of glassy materials and gels. Studies reflect both the static, instantaneous nature of the structure, as well as its dynamic nature due to polymerization and the full array of biological processes. While it is unlikely that a single unifying approach will evolve from this diversity, it is the hope that a better appreciation of the various perspectives will lead to a highly coordinated approach to exploring the essential problems and better discussions among investigators with differing views.
Introduction To Cell Mechanics And Mechanobiology
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Author : Christopher R. Jacobs
language : en
Publisher: Garland Science
Release Date : 2012-11-16
Introduction To Cell Mechanics And Mechanobiology written by Christopher R. Jacobs and has been published by Garland Science this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-11-16 with Medical categories.
Introduction to Cell Mechanics and Mechanobiology is designed for a one-semester course in the mechanics of the cell offered to advanced undergraduate and graduate students in biomedical engineering, bioengineering, and mechanical engineering. It teaches a quantitative understanding of the way cells detect, modify, and respond to the physical prope
Mechanics Of The Cell
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Author : David H. Boal
language : en
Publisher: Cambridge University Press
Release Date : 2012-01-19
Mechanics Of The Cell written by David H. Boal and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-01-19 with Science categories.
New edition exploring the mechanical features of biological cells for advanced undergraduate and graduate students in physics and biomedical engineering.
Cell Mechanics
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Author : Yu-Li Wang
language : en
Publisher: Academic Press
Release Date : 2007-07-05
Cell Mechanics written by Yu-Li Wang and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-07-05 with Science categories.
Cell mechanics is the field of study that looks at how cells detect, modify, and respond to the physical properties of the cell environment. Cells communicate with each other through chemical and physical signals which are involved in a range of process from embryogenesis and wound healing to pathological conditions such as cancerous invasion. Similar principles are also likely to be critical for success in regenerative medicine. Cell mechanics is thus central to understanding these principles. As cell mechanics draws from the fields of biology, chemistry, physics, engineering, and mathematics, this book aims not only to provide a collection of research methods, but also to develop a common language among scientists who share the interest in cell mechanics but enter the field with diverse backgrounds. To this end all of the contributing authors have sought to explain in plain language the nature of the biological problems, the rationale for the approaches, in addition to the methods themselves. In addition, to balance practical utility against conceptual advances, Cell Mechanics has intentionally included both chapters that provide detailed recipes and those that emphasize basic principles. Presents a distinctive emphasis on matrix mechanics and their interplay with cell functions Includes highly significant topics relevant to basic and translational research, as well as tissue engineering Emphasizes mechanical input and output of cells
Developing Force Measurement Techniques For Cell Mechanics And Adhesion
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Author : Tianrong Jin
language : en
Publisher:
Release Date : 2016
Developing Force Measurement Techniques For Cell Mechanics And Adhesion written by Tianrong Jin and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016 with Biomechanics categories.
Cytoskeletal Mechanics
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Author : Mohammad R. K. Mofrad
language : en
Publisher:
Release Date : 2006
Cytoskeletal Mechanics written by Mohammad R. K. Mofrad and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006 with Cytoskeleton categories.
This book presents views on approaches to modeling cell mechanics. The diversity of opinions stems from the different backgrounds of those who have contributed to the field. The authors come from the biophysics, bioengineering, and physical chemistry communities, and each joins the discussion with their unique perspective on biological systems.
Cytoskeletal Mechanics
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Author : Mohammad R. K. Mofrad
language : en
Publisher:
Release Date : 2005*
Cytoskeletal Mechanics written by Mohammad R. K. Mofrad and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005* with Cytoskeleton categories.
Cellular Mechanics And Biophysics
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Author : Claudia Tanja Mierke
language : en
Publisher: Springer Nature
Release Date : 2020-10-30
Cellular Mechanics And Biophysics written by Claudia Tanja Mierke and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-10-30 with Science categories.
This book focuses on the mechanical properties of cells, discussing the basic concepts and processes in the fields of immunology, biology, and biochemistry. It introduces and explains state-of-the-art biophysical methods and examines the role of mechanical properties in the cell/protein interaction with the connective tissue microenvironment. The book presents a unique perspective on cellular mechanics and biophysics by combining the mechanical, biological, physical, biochemical, medical, and immunological views, highlighting the importance of the mechanical properties of cells and biophysical measurement methods. The book guides readers through the complex and growing field of cellular mechanics and biophysics, connecting and discussing research findings from different fields such as biology, cell biology, immunology, physics, and medicine. Featuring suggestions for further reading throughout and addressing a wide selection of biophysical topics, this book is an indispensable guide for graduate and advanced undergraduate students in the fields of cellular mechanics and biophysics.
Mechanobiology
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Author : Ronen Zaidel-Bar
language : en
Publisher: Springer Nature
Release Date : 2023-01-01
Mechanobiology written by Ronen Zaidel-Bar and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-01-01 with Sports & Recreation categories.
This detailed book collects methodologies exploring mechanobiology, the involvement of mechanical forces in cell fate specification and in controlling single and collective cell behaviors such as directed migration, morphogenesis, wound healing, and the immune response. The volume features methods to quantify the mechanical properties of cells and adhesion proteins, to expose cells to external mechanical forces, to quantitatively characterize mechano-responses at various scales, to measure forces applied by cells on the extracellular matrix, as well as chapters on force measurement inside cells, probing cell signaling and gene expression in response to force, and biophysical modeling of cell shape and protein dynamics. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary material and reagents, step-by-step and readily reproducible protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Mechanobiology: Methods and Protocols aims to provide meaningful tools for cell and developmental biologists approaching the study of cell and tissue dynamics from a mechanobiological perspective, molecular biologists interested in the effects of force on proteins, as well as for cancer biologists and biophysicists.