Mechanisms And Concepts In Toxicology
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Mechanisms And Concepts In Toxicology
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Author : W. Norman Aldridge
language : en
Publisher: CRC Press
Release Date : 1996-02-15
Mechanisms And Concepts In Toxicology written by W. Norman Aldridge and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996-02-15 with Medical categories.
Illustrating concepts and types of toxicity from a mechanistic point of view, this book focuses on research procedures in toxicology. The book uses examples of chemical intoxicants to illustrate mechanisms in each stage of toxicity.
Concepts In Toxicology
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Author : John H. Duffus
language : en
Publisher: Royal Society of Chemistry
Release Date : 2009
Concepts In Toxicology written by John H. Duffus and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009 with Medical categories.
This is a reference for those who need to understand the fundamental toxicological concepts that underlie both the scientific development of the subject and its practical applicaton in regulation and management of chemical safety.
Molecular And Biochemical Toxicology
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Author : Robert C. Smart
language : en
Publisher: John Wiley & Sons
Release Date : 2018-01-04
Molecular And Biochemical Toxicology written by Robert C. Smart and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-01-04 with Science categories.
Written as an advanced text for toxicology students, this book is much more than an introduction and provides in-depth information describing the underlying mechanisms through which toxicants produce their adverse responses. • Links traditional toxicology to modern molecular techniques, important for teaching to graduate courses and professional studies • Uses a didactic approach with basic biological or theoretical background for the methodology presented • Brings together and comprehensively covers a range of dynamic aspects in biochemical and molecular toxicology • Guides student and professional toxicologists in comprehending a broad range of issues, compiled and authored by a diverse group of experts • “A good introductory textbook covering the biochemical toxicology of organic substances and the relevant methodology in some detail.... It offers good value for money and can be recommended as a textbook for appropriate courses” – BTS Newsletter review of the 4th edition
Mechanistic Toxicology
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Author : Urs A. Boelsterli
language : en
Publisher: CRC Press
Release Date : 2007-03-23
Mechanistic Toxicology written by Urs A. Boelsterli and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-03-23 with Medical categories.
A thorough understanding of cellular and molecular mechanisms involved in the individual expression of toxic effects provides an important tool for assessment of human health risk. New aspects, major advances, and new areas in molecular and cellular biology and toxicology demand updated sources of information to elucidate the functional mechanics of human toxicology. Mechanistic Toxicology: The Molecular Basis of How Chemicals Disrupt Biological Targets, Second Edition retains the accessible format of the original to present the general principles that link xenobiotic-induced toxicity with the molecular pathways that underlie these toxic effects. Extensively illustrated, this book forms a conceptual bridge between multiple events at the molecular level and the determinants of toxicity at the physiological and cellular level. Specific examples of drugs, environmental pollutants, and other chemicals are carefully chosen to illustrate and highlight the fundamental mechanisms of toxicity at different toxicokinetic and toxicodynamic levels. The book includes references and review articles at the end of each chapter, as well as boxed text for relevant review information on biological, biochemical, molecular, and toxicological background. Linking molecular pathways to more general biomedical contexts, the author ensures that the reader is not lost in the details and instead receives a broad understanding of the processes underlying xenobiotic toxicity. New in the Second Edition Updated chapters Types of toxic responses Disruption of signal transduction by xenobiotics Disruption of mitochondrial function Novel mechanisms derived from systems toxicology
Toxicology And Risk Assessment
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Author : Helmut Greim
language : en
Publisher: John Wiley & Sons
Release Date : 2008-04-15
Toxicology And Risk Assessment written by Helmut Greim and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-04-15 with Science categories.
This new book, written by two outstanding scientists in the field, describes the basic principles of toxic mechanisms and organ toxicity, providing detailed information on specific mechanisms or chemicals for exemplification. The goal is to provide sufficient information that the reader becomes familiar with the basic concepts in toxicology to enable him or her to understand the basic principles in toxicology and to evaluate the risks at given exposures. With this basic understanding the reader also will be able to critically evaluate the available information on a chemical and to identify data gaps. In addition to the introductory chapters the book will offer the following systematic information, presented in six special sections: Principles in Toxicology Organ Toxicology Methods in Toxicology Risk Assessment Risk Management Toxicity of Chemicals Fulfilling a demand for such a book, this will be a welcomed introductory text for students and non-experts alike to focus on and understand the principles of hazard identification and risk assessment of toxicants. Relevant to all those studying toxicology, biochemistry, biology, medicine and chemistry, as well as toxicologists in hospitals, universities and in industry.
Toxicology
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Author : C. P. Stewart
language : en
Publisher: Elsevier
Release Date : 2013-10-22
Toxicology written by C. P. Stewart and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-22 with Medical categories.
Toxicology: Mechanisms and Analytical Methods, Volume II provides an account of the general methods of chemical analysis available to the toxicologist, discussion of the principles on which they are based, and a survey of the material to which they are applied. The volume supplements the methods presented in the first volume. It provides specific examples of general procedures; considers the important groups of poisons; arranges the order of extraction from biological material; and discusses the methods for identifying and determining the members of each poison group. The book will be invaluable to toxicologists, clinical chemists, and biochemists.
Molecular And Cellular Mechanisms Of Toxicity
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Author : Lewis L. Smith
language : en
Publisher: CRC Press
Release Date : 2019-06-04
Molecular And Cellular Mechanisms Of Toxicity written by Lewis L. Smith and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-06-04 with Medical categories.
First Published in 1995: Written by specialists in their fields, this book contains short reviews intended to highlight points of growing interest in mechanistic toxicology. The first section considers selected aspects of molecular mechanisms, including selectivity of toxic agents and repair processes in the nervous system, toxicity of oxygen, fibers and aflatoxins. The second section discusses the interactions of carcinogens with DNA, and other targets, and their relevance to both molecular dosimetry of exposure and development of cancer. The final part is concerned with cellular and genetic aspects and includes coverage of some of the most recent and rapidly developing problems in toxicology.
Mechanisms And Concepts In Toxicology
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Author : W. Norman Aldridge
language : en
Publisher: CRC Press
Release Date : 1996-02-15
Mechanisms And Concepts In Toxicology written by W. Norman Aldridge and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996-02-15 with Medical categories.
Illustrating concepts and types of toxicity from a mechanistic point of view, this book focuses on research procedures in toxicology. The book uses examples of chemical intoxicants to illustrate mechanisms in each stage of toxicity.
Biological Concepts And Techniques In Toxicology
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Author : Jim E. Riviere
language : en
Publisher: CRC Press
Release Date : 2006-03-06
Biological Concepts And Techniques In Toxicology written by Jim E. Riviere and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-03-06 with Medical categories.
Highlighting the latest advances in molecular biology, mathematical modeling, quantitative risk assessment, and biopharmaceutical development, this reference presents how current scientific applications and methods impact and revolutionize mainstream toxicological research. Presenting findings from disciplines that will impact the future of toxicol
An Introduction To Toxicology
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Author : Philip C. Burcham
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-19
An Introduction To Toxicology written by Philip C. Burcham and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-19 with Medical categories.
This book provides a readable introduction to modern toxicology with a particular focus on the mechanisms underlying the induction of toxicity by foreign substances. Since bioactivation is central to many toxic syndromes, special interest is devoted to chemicals that undergo conversion to toxic metabolites that induce toxic effects as diverse as cancer, birth defects and organ injury. The molecular consequences accompanying damage to cellular DNA and proteins is explored together with the relevance of toxicological paradigms to human diseases caused by alcohol and tobacco. The discipline of toxicology has developed rapidly since the thalidomide disaster in the 1960’s as scientists worldwide seek to understand the adverse health effects of human medicines, environmental pollutants, consumer chemicals and industrial reagents. An Introduction to Toxicology is intended to supplement the recommended reading list of undergraduate and graduate programs in toxicology and pharmacology as an enjoyable, accessible primer with illustrations that “unpack” the concepts being discussed in the text.