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Mechanisms Of Drug Interactions


Mechanisms Of Drug Interactions
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Mechanisms Of Drug Interactions


Mechanisms Of Drug Interactions
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Author : Patrick F. D'Arcy
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Mechanisms Of Drug Interactions written by Patrick F. D'Arcy and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.


Over the years a number of excellent books have classified and detailed drug drug interactions into their respective categories, e.g. interactions at plasma protein binding sites; those altering intestinal absorption or bioavailability; those involving hepatic metabolising enzymes; those involving competition or antagonism for receptor sites, and drug interactions modifying excretory mechanisms. Such books have presented extensive tables of interactions and their management. Although of considerable value to clinicians, such publica tions have not, however, been so expressive about the individual mechanisms that underlie these interactions. It is within this sphere of "mechanisms" that this present volume specialises. It deals with mechanisms of in vitro and in vivo, drug-drug, drug food and drug-herbals interactions and those that cause drugs to interfere with diagnostic laboratory tests. We believe that an explanation of the mechanisms of such interactions will enable practitioners to understand more fully the nature of the interactions and thus enable them to manage better their clinical outcome. If mechanisms of interactions are better understood, then it may be pos sible for the researcher to develop meaningful animal/biochemical/tissue cul ture or physicochemical models to which new molecules could be exposed during their development stages. The present position, which largely relies on patients experiencing adverse interactions before they can be established or documented, can hardly be regarded as satisfactory. This present volume is classified into two major parts; firstly, pharmacoki netic drug interactions and, secondly, pharmacodynamic drug interactions.



Drug Interactions


Drug Interactions
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Author : Ivan H. Stockley
language : en
Publisher:
Release Date : 1996

Drug Interactions written by Ivan H. Stockley and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996 with Medical categories.


This is a source book of adverse drug reactions covering their clinical importance, mechanisms and management. This fourth edition has been revised from an extensive database. Major interaction mechanisms are followed by alphabetically-arranged material covering all the drug groups. As with prior editions, there is a series of monographs with a consistent plan devised to offer quick and easy reading. Both British and American drug names have been used throughout the book and bibliogrpahies are provided for those who wish to use the book as a reference source.



Handbook Of Drug Interaction And The Mechanism Of Interaction


Handbook Of Drug Interaction And The Mechanism Of Interaction
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Author : Qutaiba A. Ibrahim
language : en
Publisher: Xlibris Corporation
Release Date : 2011-09-28

Handbook Of Drug Interaction And The Mechanism Of Interaction written by Qutaiba A. Ibrahim and has been published by Xlibris Corporation this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-09-28 with Medical categories.


This Handbook is offered as a general summary of information for physicians, pharmacists, nurses and other health professionals. Inappropriate administration of interacting drugs to patients can result in severe injury or death.



Drug Interactions And Their Mechanisms


Drug Interactions And Their Mechanisms
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Author : Ivan H. Stockley
language : en
Publisher:
Release Date : 1973

Drug Interactions And Their Mechanisms written by Ivan H. Stockley and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1973 with categories.




Stockley S Drug Interactions


Stockley S Drug Interactions
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Author : Karen Baxter
language : en
Publisher:
Release Date : 2006

Stockley S Drug Interactions written by Karen Baxter and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006 with Arzneimittelwechselwirkung categories.


First published over twenty years ago, Stockley's Drug Interactions is still the most indispensable and authoritative international source of drug interaction information. Based upon the many thousands of published clinical papers and reports, it provides a series of detailed yet concise monographs designed for quick and easy reference. Each monograph contains a summary, clinical evidence for the interaction under discussion, its probable mechanism, clinical importance and management. Individual interactions are assembled alphabetically into chapters, grouped therapeutically, pharmacologically or individually. Both Recommended International Nonproprietary Names (rlNN) and US Adopted Names (USAN) are used throughout the book



Stockley S Drug Interactions


Stockley S Drug Interactions
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Author : Karen Baxter
language : en
Publisher:
Release Date : 2007-11

Stockley S Drug Interactions written by Karen Baxter and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-11 with Medical categories.


An international source of drug interaction information. Based upon the many thousands of published clinical papers and reports, it provides a series of monographs designed for easy reference. Each monograph contains a summary, clinical evidence for the interaction under discussion, its probable mechanism, clinical importance and management.



Mechanisms Of Drug Interactions


Mechanisms Of Drug Interactions
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Author : Margaret E. Dodson
language : en
Publisher:
Release Date : 1973*

Mechanisms Of Drug Interactions written by Margaret E. Dodson and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1973* with Drug interactions categories.




Drug Interactions


Drug Interactions
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Author : Philip D. Hansten
language : en
Publisher:
Release Date : 1985

Drug Interactions written by Philip D. Hansten and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1985 with Medical categories.


Abstract: A reference text for clinicians, pharmacologists, and physicians provides summaries of the human in vivo interactions of drug with other medications. The text assumes a basic understanding of pharmacological and physiological principles, and delineates current knowledge on the mechanisms of drug-drug interaction, clinical significance, and precautions to be exercised during drug therapy. The drug-drug interactions are arranged by drug or drug class, but, when appropriate, interactions for a given drug may be given in several locations in the text. All of the drug-drug interaction covered have been assigned to 1 of 3 categories of clinical significance (viz., major, moderate, or minor) based on the severity of the potential interaction. The interactions are listed under 16 drug categories: antiarrhythmics, oral anticogulants, general anticoagulants, antidiabetics, antihypertensive, anti-infective, anti-neoplastic, digitalis drug, diuretics, monoamine oxidase inhibitors, tricylic antidepressants,and drug interactions with ethanol, hormones, phenothiazine, and salicylate. (wz).



Drug Interactions In Infectious Diseases Mechanisms And Models Of Drug Interactions


Drug Interactions In Infectious Diseases Mechanisms And Models Of Drug Interactions
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Author : Manjunath P. Pai
language : en
Publisher: Springer
Release Date : 2018-03-05

Drug Interactions In Infectious Diseases Mechanisms And Models Of Drug Interactions written by Manjunath P. Pai and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-03-05 with Medical categories.


The 4th edition of Drug Interactions in Infectious Diseases is being split into two separate volumes – “Mechanisms and Models of Drug Interactions” and “Antimicrobial Drug Interactions”. This volume, “Mechanisms and Models of Drug Interactions,” delivers a text that enhances clinical knowledge of the complex mechanisms, risks, and consequences of drug interactions associated with antimicrobials, infection, and inflammation. The book provides a comprehensive review of basic clinical pharmacology with a focus on metabolism and transporter-mediated drug interactions. The chapters address materials that cannot be retrieved easily in the medical literature, including materials focused on the complex interrelationship of acute infection, inflammation, and the risk of drug interactions in the Drug-Cytokine chapter. The Food-Drug and Herb-Drug interactions chapters remain definitive resources. A new chapter on in vitro modeling of drug interactions is included along with updates on design and data analysis of clinical drug interaction studies. Authoritative discussion of models for regulatory decision-making on drug-drug interactions provides the necessary framework to aid antimicrobial drug development. This concise review of the mechanisms and models of drug interactions provides important insights to health care practitioners as well as scientists in drug development.



Handbook Of Drug Nutrient Interactions


Handbook Of Drug Nutrient Interactions
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Author : Joseph I. Boullata
language : en
Publisher: Springer Science & Business Media
Release Date : 2004-04-17

Handbook Of Drug Nutrient Interactions written by Joseph I. Boullata and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-04-17 with Medical categories.


Although there is agreat deal ofliterature regarding drug-nutrientinteractions (DNis ), there are limited sources of up-to-date comprehensive information. The Handbook of Drug-Nutrient Interactions admirably fills this gap. The editors, Dr. Joseph 1. Boullata and Dr. Vincent T. Armenti, ha ve a wealth of experience in this therapeutic ar ea and ha ve assembled a fine cadre of chapter authors who have individually contributed their high level of expertise. As treatment for many diseases becomes increasingly complex with multiple drug therapies scheduled at varying times, the need to identify clinically significant DNis is an essential part of medication management. This is a shared responsibility between health care professionals to interpret available data and individualize an approach to therapy that is compatible with the patient' s disease state, life stage, and dietary intake. Awareness ofthe significance of drug-food interactions is generally lacking. Although many texts contain lengthy lists of possible interactions, few data are provided for the clinician to gain an understanding of the mechanism of action of the interaction and subsequently apply the information to a particular patient or group of patients. For example, in the management of patients with HN -AIDS who are taking complex prescribed drug regimens, herbal products, and nutritional supplements, many of which are affected by dietary intake, careful attention to D Nls is a critic al component of therapy. Clinicians need to take account of not only the well-documented interactions between drugs and nutrients, but also the less obvious effects on drug-nutrient disposition and metabolism.