Mechanisms Of Intracellular Trafficking And Processing Of Proproteins

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Mechanisms Of Intracellular Trafficking And Processing Of Proproteins

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Author : Y. Peng Loh
language : en
Publisher: CRC Press
Release Date : 1992-10-23

Mechanisms Of Intracellular Trafficking And Processing Of Proproteins written by Y. Peng Loh and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992-10-23 with Science categories.

Mechanisms of Intracellular Trafficking and Processing of ProProteins provides an in-depth discussion of the cellular organization and current views of the molecular mechanisms underlying the trafficking, sorting, and processing of various classes of proproteins. The book covers the mechanisms of pro-protein translocation across the rough endoplasmic reticulum (RER) membrane and subsequent transport to the Golgi apparatus, molecular sorting and retention signals involved in directing pro-proteins to various cellular compartments, and the specific enzymes mediating different posttranslational modification steps. It is the only book that covers the principles of intracellular trafficking and processing of proproteins using examples representative of different classes of proproteins in the cell. New classes of enzymes, especially proteases with unique specificities, are examined as well. Mechanisms of Intracellular Trafficking and Processing of ProProteins presents a wealth of information valuable to cell biologists, endocrinologists, neurobiologists, enzymologists, and biochemists. Students studying molecular endocrinology, neurobiology, and cell biology will also find the book to be a useful text.

Aspartic Proteinases

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Author : Kenji Takahashi
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Aspartic Proteinases written by Kenji Takahashi and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.

The 5th International Conference on Aspartic Proteinases was held on September 19 through 24, 1993, at Naito Museum of Pharmaceutical Science and Industry, Kawashima cho, Gifu Prefecture, Japan, about 15 miles northwest of Nagoya City. About 100 scientists attended the conference, including 52 from 14 countries outside Japan, and 32 papers were presented by invited speakers, and 58 papers as posters. The purpose of this conference was to present and discuss new information on the structure, function, and biology, and related topics, including biomedical implications, of aspartic proteinases, and this book is a collec tion of nearly all the papers presented at the meeting. Aspartic proteinases belong to one of the four major classes of proteinases, the others being serine, cysteine, and metalloproteinases, and are so called since they have two catalytic aspartic acid residues in common in their active sites. Most of them are optimally active at acidic pH, hence the long-used name "acid proteinases," which, indeed, was the major title of the first conference of this series. However, some of them are active at around neutral pH, indicating their physiological roles in a wider range of pH than hitherto considered.

Exploring Genetic Mechanisms

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Author : Maxine Singer
language : en
Publisher: University Science Books
Release Date : 1997-05-07

Exploring Genetic Mechanisms written by Maxine Singer and has been published by University Science Books this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997-05-07 with Medical categories.

An outstanding group of scientists have collaborated in the collection of case studies that comprise this major text-reference book. It examines in detail how genes operate in diverse living systems, including viruses, cells and more complex organisms; investigates how genotypes can be altered; and looks at the mapping and sequencing of human and other genomes. Students and professionals in biochemistry, molecular biology and genetics will enjoy this book.

Neurosecretion Secretory Mechanisms

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Author : José R. Lemos
language : en
Publisher: Springer Nature
Release Date : 2020-03-31

Neurosecretion Secretory Mechanisms written by José R. Lemos and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-03-31 with Medical categories.

How do electrical activity and calcium signals in neurons influence the secretion of peptide hormones? This volume presents the current state of knowledge regarding the electrical, calcium signaling and synaptic properties of neuroendocrine systems from both vertebrate and invertebrate systems. The contributions span in vivo and in vitro studies that address: state‐dependent plasticity, relevance of firing patterns, membrane properties, calcium flux (including dynamic imaging and homeostasis), and molecular mechanisms of exocytosis, including from non-neuronal secretory cells. The chapters focus not only on research results but also on how experiments are conducted using state-of-the-art techniques, and how the resulting data are interpreted. While there are many books on the secretory properties of neurons, this is the first to focus on the distinctive secretory properties of neuroendocrine neurons. Accordingly, it offers an important text for undergraduate and graduate neuroscience students, and will also appeal to established scientists and postdoctoral fellows. This is the eighth volume in the Masterclass in Neuroendocrinology series* - now a co-publication between Springer Nature and the INF (International Neuroendocrine Federation). *Volumes 1-7 published by Wiley

Aspartic Proteinases Physiology And Pathology

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Author : Martin Fusek
language : en
Publisher: CRC Press
Release Date : 2019-10-10

Aspartic Proteinases Physiology And Pathology written by Martin Fusek and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-10-10 with Medical categories.

Published in 1995: Aspartic Proteinases: Physiology and Pathology focuses on the advantages and limitations of the use of proteinases and their inhibitors in human pathology. A virus-specific aspartic proteinase enzyme is required for the maturation of a virus. If the enzyme can be eliminated, so can the maturation of the virus. This book reviews the wealth of recently published information sparked by the renewed interest in these enzymes.

Textbook Of Energy Balance Neuropeptide Hormones And Neuroendocrine Function

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Author : Eduardo A. Nillni
language : en
Publisher: Springer
Release Date : 2018-07-20

Textbook Of Energy Balance Neuropeptide Hormones And Neuroendocrine Function written by Eduardo A. Nillni and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-07-20 with Medical categories.

This textbook presents for the first time a comprehensive body of the latest knowledge in the field of neuropeptides and their action on energy balance. It contains a detailed and comprehensive account of the specific hypothalamic peptides in regards to their roles in energy balance, food intake control and co-morbidities, to better understand the patho-physiology of obesity. The textbook includes an examination the history of the evolution of human society from a thin to the obese phenotype and, within that context, how modern society habits and industrial food production did not respect the evolutionary trait resulting in changes in the energy balance set point. It provides a novel conceptualization of the problem of obesity when considering the biochemistry of peptide hormones and entertaining novel ideas on multiple approaches to the problems of energy balance, as well as demonstrates and explains why alterations in pro-hormone processing are paramount to understand metabolic disease. This text is excellent material for teaching graduate and medical school courses, as well as a valuable resource for researchers in biochemistry, cell, and molecular biology, neuroscientists, physician endocrinologists, and nutritionists.

The Peptidergic Neuron

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Author : B. Krisch
language : en
Publisher: Birkhäuser
Release Date : 2012-12-06

The Peptidergic Neuron written by B. Krisch and has been published by Birkhäuser this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.

Neuropeptides rank among the phylogenetically oldest interneuronal signal substances. In the concept of neuro-secretion they were identified as neurohormones by which - via the blood - the brain regulates peripheral functions. It is now evident that the neuropeptides act as neurotransmitters/-modulators, as (neuro-)hormones, and paracrine or autocrine signal substances in diverse parts of the body. This book reviews, in several comprehensive articles written by distinguished specialists, the state of the art in the field of neuropeptides and peptidergic neurons. Special topics concern molecular aspects of processing, release and degradation of neuropeptides, receptors and signal transduction, comparative and behavioural aspects, and immunoregulatory effects of neuropeptides and their involvement on pathology of the central nervous system.

National Library Of Medicine Current Catalog

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Author : National Library of Medicine (U.S.)
language : en
Publisher:
Release Date : 1993

National Library Of Medicine Current Catalog written by National Library of Medicine (U.S.) and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993 with Medicine categories.

The Parathyroids

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Author : John P. Bilezikian
language : en
Publisher: Elsevier
Release Date : 2001-07-21

The Parathyroids written by John P. Bilezikian and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-07-21 with Medical categories.

Written by world experts, this books follows upon the monumental success of the first edition of The Parathyroids, which was universally acclaimed as the best text on the subject. An authoritative reference that spans the basic science of parathyroid hormone treatment to major clinical disorders in a superb, single compendium, The Parathyroids offers an objective and authoritative view on controversial clinical issues in this rapidly changing field. Every medical school library and virtually every major hospital library will need this book as a reference for students and clinicians. Key Features * Offers objective and authoritative reviews on controversial clinical issues * Written by world experts on parathyroid hormone and its disorders * Superb, state-of-the-art compendium in one convenient volume * Bridges basic science of parathyroid hormone to major clinical disorders * Practical information on clinical management of parathyroid hormone disorders

Abc Transporters Biochemical Cellular And Molecular Aspects

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Author : Suresh V. Ambudkar
language : en
Publisher: Gulf Professional Publishing
Release Date : 1998-07-31

Abc Transporters Biochemical Cellular And Molecular Aspects written by Suresh V. Ambudkar and has been published by Gulf Professional Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998-07-31 with Medical categories.

The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. More than 285 volumes have been published (all of them still in print) and much of the material is relevant even today-truly an essential publication for researchersin all fields of life sciences. Prokaryotic ABC Transporters Eukaryotic ABC Transporters Nonmammalian ABC Transport Systems Mammalian P-Glycoproteins Multidrug Resistance Associated Protein Cystic Fibrosis Transmembrane Conductance Regulator Sulfonylurea Receptor Intracellular ABC Transporters