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Membrane Protein Transport

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Membrane Transporters And Channels As Targets For Drugs

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Author : Graça Soveral
language : en
Publisher: Frontiers Media SA
Release Date : 2020-01-03

Membrane Transporters And Channels As Targets For Drugs written by Graça Soveral and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-01-03 with categories.

Transporters and channels are membrane proteins that mediate the traffic of metabolites, water and ions across biological membranes. Membrane transport proteins are crucial to maintain homeostasis and assure cell survival upon intracellular or environmental stress. A failure of any of these transport systems may have dramatic consequences for cell function. There is increasing evidence that membrane transport proteins play important functions in healthy conditions and that their absence or dysfunction may cause diseases. In recent years much attention has been paid to diseases resulting from defective transporters (“carrier diseases”) and ion channels (“channelopathies”). Very interestingly, altered expression of transporters has been described in several human pathologies. On this basis, many transport proteins are well acknowledged targets for drugs. Many others are involved in drug delivery and disposition and/or are considered potential targets. Others are off-targets for drugs and then, are responsible for side effects. Thus, membrane protein drug discovery is now an emerging field where the search for physiological mechanisms of regulation and for chemical compounds as modulators of transport activity, present new opportunities for drug development and for new therapies. This Research Topic addresses the latest research advances in membrane transport proteins, stimulating future research on these important protein families.

Membrane Protein Transport

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Author : S.S. Rothman
language : en
Publisher: Elsevier
Release Date : 1995-06-28

Membrane Protein Transport written by S.S. Rothman and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995-06-28 with Science categories.

This is the first volume in a series on membrane protein transfer. Membrane protein transport underlies the topological disposition of many proteins within cells and it is this disposition that allows for the co-ordination of the central cellular processes, such as metabolism.

Membrane Protein Transport

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Author : S.S. Rothman
language : en
Publisher: Elsevier Science
Release Date : 1995-11-03

Membrane Protein Transport written by S.S. Rothman and has been published by Elsevier Science this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995-11-03 with Science categories.

Molecular Biology Of The Cell

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Author : Bruce Alberts
language : en
Publisher:
Release Date : 2002

Molecular Biology Of The Cell written by Bruce Alberts and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Cytology categories.

Molecular Biology Of The Cell

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Author :
language : en
Publisher:
Release Date : 2002

Molecular Biology Of The Cell written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Cells categories.

Membrane Protein Transport

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Author :
language : en
Publisher:
Release Date : 1995

Membrane Protein Transport written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995 with Biological transport categories.

Molecular Biology Of The Cell

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Author :
language : en
Publisher:
Release Date : 2004

Molecular Biology Of The Cell written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with Cells categories.

Vectorial Transport Of Proteins Into And Across Membranes

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Author :
language : en
Publisher: Academic Press
Release Date : 1991-10-11

Vectorial Transport Of Proteins Into And Across Membranes written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1991-10-11 with Science categories.

This is the third volume in this series covering protein translocation within and between cells. Volumes 31 and 32, Vesicular Transport, Parts A and B, treated techniques for eukaryotic cells available as of 1989. Vectorial Transport of Proteins into and across Membranes, brings together new methods and new topics as of 1991. Highlights include use of anti-idiotype antibodies, gene fusions, transcription, crosslinking, pulse-labeling, and reconstitution. Describes contemporary approaches for studying protein transport, protein topology and organelle biogenesis Covers methods from pre-eminent laboratories including: In vitro and in vivo investigations; Biochemical and immunological techniques; Prokaryote, chloroplast, mitochondria, peroxisome, and rough endoplasmic reticulum membranes