Metabolic Conjugation And Metabolic Hydrolysis
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Metabolic Conjugation And Metabolic Hydrolysis
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Author : William H. Fishman
language : en
Publisher: Academic Press
Release Date : 2014-05-10
Metabolic Conjugation And Metabolic Hydrolysis written by William H. Fishman and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-05-10 with Science categories.
Metabolic Conjugation and Metabolic Hydrolysis, Volume I is a comprehensive account of the main conjugation mechanisms and hydrolytic reactions. Topics covered range from the metabolic conjugates of steroids and N-hydroxy compounds to the effects of conjugated steroids on enzymes. The glucuronic acid pathway is also discussed, along with sulfoconjugation and sulfohydrolysis. Comprised of eight chapters, this volume first looks at the history of conjugation mechanisms before proceeding to developments in metabolic conjugations. The isolation, recognition, enzymic formation and hydrolysis, and the possible significance of steroid N-acetylglucosaminides and glucosides are considered. The book also examines the mechanisms involved in the enzymic formation of N-hydroxy compounds; the pathways by which N-hydroxy compounds may be further metabolized in vivo; and the chemical properties of conjugates of N-hydroxy compounds, particularly as these properties are related to the generation of reactive cations or free radicals in vivo. The possible role of conjugates of N-hydroxy compounds in the mechanism of carcinogenesis by aromatic amines and their N-acyl derivatives is also analyzed. Finally, glycoprotein and mucopolysaccharide hydrolysis and the role of hydrolases in cellular death are described. This monograph will be a useful resource for biologists, biochemists, physiologists, and pharmacologists.
Metabolic Conjugation And Metabolic Hydrolysis
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Author : William H. Fishman
language : en
Publisher: Academic Press
Release Date : 2014-05-10
Metabolic Conjugation And Metabolic Hydrolysis written by William H. Fishman and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-05-10 with Science categories.
Metabolic Conjugation and Metabolic Hydrolysis, Volume III is a comprehensive account of the status of metabolic conjugation and metabolic hydrolysis. Topics covered range from the metabolism of steroid hormone conjugates and the genetic control of acid hydrolases to acetylation of drugs. Biochemical mechanisms in methyl group transfer are also discussed, along with the bilirubin conjugates of the human bile. Comprised of eight chapters, this volume first looks at the biosynthesis of animal glycoproteins before turning to an analysis of the metabolism of the conjugates of steroid hormones. The reader is then introduced to the genetic mechanisms that regulate acid hydrolases; control of metabolic hydrolysis in the lysosome-vacuolar apparatus; and the biochemical mechanisms underlying methyl group transfer. The final chapter is devoted to membrane phosphohydrolases, with emphasis on certain common features of membrane enzymes or of enzymes associated with membranes. Membrane transferases and hydrolases are also considered, including adenosine triphosphatase and adenyl cyclase. This book will be a useful resource for biologists, biochemists, physiologists, and pharmacologists.
Metabolic Conjugation And Metabolic Hydrolysis
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Author : William H. Fishman
language : en
Publisher:
Release Date : 1970
Metabolic Conjugation And Metabolic Hydrolysis written by William H. Fishman and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1970 with Biochemistry categories.
Metabolic Conjugation And Metabolic Hydrolysis
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Author : William H. Fishman
language : en
Publisher:
Release Date : 1970
Metabolic Conjugation And Metabolic Hydrolysis written by William H. Fishman and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1970 with Biochemistry categories.
Metabolic Conjugation and Metabolic Hydrolysis ...
Metabolic Conjugation And Metabolic Hydrolysis
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Author : Etienne-Emile Baulieu
language : en
Publisher:
Release Date : 1973
Metabolic Conjugation And Metabolic Hydrolysis written by Etienne-Emile Baulieu and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1973 with categories.
Metabolic Conjugation And Metabolic Hydrolysis V 1 2
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Author : W. H. Fishman
language : en
Publisher:
Release Date : 1970
Metabolic Conjugation And Metabolic Hydrolysis V 1 2 written by W. H. Fishman and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1970 with categories.
Metabolic Conjugation And Metobolic Hydrolysis
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Author : W.H. Fishman
language : en
Publisher:
Release Date : 1970
Metabolic Conjugation And Metobolic Hydrolysis written by W.H. Fishman and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1970 with categories.
Hydrolysis In Drug And Prodrug Metabolism
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Author : Bernard Testa
language : en
Publisher: John Wiley & Sons
Release Date : 2003-08
Hydrolysis In Drug And Prodrug Metabolism written by Bernard Testa and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-08 with Science categories.
Many drugs and other xenobiotics (e.g., preservatives, insecticides, and plastifiers) contain hydrolyzable moieties such as ester or amide groups. In biological media, such foreign compounds are, therefore, important substrates for hydrolytic reactions catalyzed by hydrolases or proceeding non-enzymatically. Despite their significance, until now, no book has been dedicated to hydrolysis and hydrolases in the metabolism of drugs and other xenobiotics. This work fills a gap in the literature and reviews metabolic reactions of hydrolysis and hydarion from the point of views of enzymes, substrates, and reactions.
Metabolism Of Xenobiotics Detoxification
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Author : U Satyanarayana
language : en
Publisher: Elsevier Health Sciences
Release Date : 2014-11-07
Metabolism Of Xenobiotics Detoxification written by U Satyanarayana and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-11-07 with Medical categories.
Metabolism of xenobiotics (detoxification) Metabolism of xenobiotics (detoxification)
Metabolic Conjugation And Metabolic Hydrolyses
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Author : William H. Fishman
language : en
Publisher:
Release Date : 1970
Metabolic Conjugation And Metabolic Hydrolyses written by William H. Fishman and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1970 with categories.