Methylotrophs
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Biology Of Methylotrophs
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Author : Israel A. Goldberg
language : en
Publisher: Elsevier
Release Date : 2013-10-22
Biology Of Methylotrophs written by Israel A. Goldberg and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-22 with Nature categories.
Biology of Methylotrophs introduces the reader to the study of methylotrophs - microorganisms that use reduced one-carbon compounds for growth. The book is divided into five parts. Part I covers the taxonomy, morphology, and ultrastructure of methylotrophic bacteria. Part II discusses the processes involved in their growth and metabolism. Part III talks about the possible applications of methylotrophs and their enzymes in industrial fields as well as chemistry. Part IV deals with the molecular genetics and the gene expression of methylotrophs, and Part V deals with their habitat and role in the environment. The text is recommended for microbiologists who would like to be acquainted with the subject or make further studies about methylotrophs.
The Biochemistry Of Methylotrophs
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Author : C. Anthony
language : en
Publisher:
Release Date : 1982
The Biochemistry Of Methylotrophs written by C. Anthony and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1982 with Science categories.
Methylotrophs Microbiology Biochemistry And Genetics
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Author : Hou
language : en
Publisher: CRC Press
Release Date : 2018-01-18
Methylotrophs Microbiology Biochemistry And Genetics written by Hou and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-01-18 with Science categories.
This book offers a comprehensive examination of the microbiology, biochemistry, genetics, and applied aspects of methylotrophsThis book is intended for reference purposes at the professional level and for students at the graduate level. It is hoped that it will provide researchers with not only basic science, but also applied aspects of methylotrophs.
Methylotrophs
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Author : Ching-Tsang Hou
language : en
Publisher: Springer
Release Date : 1984-07-19
Methylotrophs written by Ching-Tsang Hou and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 1984-07-19 with Science categories.
Methylotrophs And Methylotroph Communities
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Author : Ludmila Chistoserdova
language : en
Publisher: Caister Academic Press
Release Date : 2019-04-28
Methylotrophs And Methylotroph Communities written by Ludmila Chistoserdova and has been published by Caister Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-04-28 with Science categories.
The field of methylotrophy has experienced a remarkable rejuvenation in recent years and undergone a major transformation in terms of discovery of novel types of methylotrophs, novel modes of methylotrophy and novel metabolic pathways. New questions are being asked and novel approaches are being employed to improve the current understanding of methylotrophy as a metabolic phenomenon.This comprehensive volume is a compilation of articles, some written by established scientists, others by young and upcoming methylotrophy researchers. Under the expert guidance of the editor the authors present the current data and novel outlooks in this diverse area of research, encompassing fundamentals, such as biochemistry, physiology and systematics of methylotrophs, that underpin the field, as well as newly emerging areas, such as laboratory evolution of methylotrophs, enumeration in novel environments e.g. clouds, and experimenting with synthetic methylotrophs and methylotroph communities.The volume covers a huge diversity of topics providing a timely overview of the field. It will be essential reading for everybody working in the field of methylotrophy, from seasoned researchers to newcomers to the field.
Methylotrophs And Methylotroph Communities
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Author : Ludmila Chistoserdova
language : en
Publisher:
Release Date : 2019
Methylotrophs And Methylotroph Communities written by Ludmila Chistoserdova and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019 with Methylotrophic bacteria categories.
This comprehensive volume is a compilation of articles, some written by established scientists, others by young and upcoming methylotrophy researchers. Under the expert guidance of the editor the authors present the current data and novel outlooks in this diverse area of research, encompassing fundamentals, such as biochemistry, physiology and systematics of methylotrophs, that underpin the field, as well as newly emerging areas, such as laboratory evolution of methylotrophs, enumeration in novel environments e.g. clouds, and experimenting with synthetic methylotrophs and methylotroph communit.
Methylotrophy And Methanogenesis
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Author : P. Large
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Methylotrophy And Methanogenesis written by P. Large and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
This short book attempts to give a reader who has a basic biochemical and microbiological background (one to two years at University level) an idea of the ecological, biochemical, physiological and biotechnological importance of methane, methanol and related compounds in the microbial world. Because the book covers several different scientific disciplines, readers may encounter unfamiliar terminology. The glossary at the end of the book defines the more obscure of these. The book has been written during a period of heavy teaching commit ments, and despite the helpful comments of many colleagues, it is likely that errors have crept in. As I have no co-author whom I can blame, I must accept sole responsibility for these! I wish to thank the many friends, students and colleagues who have read all or part of the manuscript: Charlie Bamforth, Rick Gibson, Jeff Green, Theo Hansen, Wim Harder, Geoff Haywood and, above all, Hans van Dijken.
Methane And Methanol Utilizers
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Author : J. Colin Murrell
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-06-29
Methane And Methanol Utilizers written by J. Colin Murrell and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-29 with Science categories.
Methane and its oxidation product, methanol, have occupied an important position in the chemical industry for many years: the former as a feedstock, the latter as a primary chemical from which many products are produced. More recently, the role played by methane as a potent "greenhouse" gas has aroused considerable attention from environmentalists and clima tologists alike. This role for C compounds has, of course, been quite 1 incidental to the myriad of microorganisms on this planet that have adapted their life-styles to take advantage of these readily available am bient sources. Methane, a renewable energy source that will always be with us, is actually a difficult molecule to activate; so any microorganism that can effect this may point the way to catalytic chemists looking for con trollable methane oxidation. Methanol, formed as a breakdown product of plant material, is also ubiquitous and has also encouraged the growth of prokaryotes and eukaryotes alike. In an attempt to give a balanced view of how microorganisms have been able to exploit these simple carbon sources, we have asked a number ofleading scientists (modesty forbids our own inclusion here) to contribute chapters on their specialist areas of the subject.
Methylotrophy And Biotechnology
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Author : Peter J. Large
language : en
Publisher: Longman Scientific and Technical
Release Date : 1988
Methylotrophy And Biotechnology written by Peter J. Large and has been published by Longman Scientific and Technical this book supported file pdf, txt, epub, kindle and other format this book has been release on 1988 with Medical categories.
Metabolic Flux Analysis And Metabolomics Of Methylotrophs
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Author : Yanfen Fu
language : en
Publisher:
Release Date : 2016
Metabolic Flux Analysis And Metabolomics Of Methylotrophs written by Yanfen Fu and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016 with Methylobacterium extorquens categories.
Methylotrophs are a group of microbes that use C1 compounds as the sole carbon and energy source, which are of interest to be used as platforms for bioconversion of C1 substrates to valuable chemicals and fuels. Methylobacterium extorquens AM1 is the best studied model organism for methylotrophs, and it uses the serine cycle for assimilation of C1 units. Methylomicrobium buryatense 5GB1 is a Type I methanotroph that uses the ribulose monophosphate (RuMP) pathway for assimilation, and it is also an industrially promising candidate for bio-conversion of methane into valuable chemicals. Metabolic flux analysis and metabolomics are two important approaches to investigate cell behavior at the level of metabolites and fluxes, which are integrative consequences of gene expression. These approaches will provide critical information for a rational strain design process in metabolic engineering iterations. In the first part of the thesis, the metabolic flux analysis approach was successfully applied to M. exorquens AM1 to investigate the metabolic network response to the trade-off between growth rate and biomass yield. Then the method was tailored to apply to M. buryatense 5GB1 for flux elucidation in core metabolism under methane growth to provide baseline information for better prediction of performance. At the end, the combined approaches were used to investigate the core metabolism of M. buryatense 5GB1 response to two substrates, methane and methanol. This work has resulted in major new insights into methylotrophic metabolism. For the serine cycle methylotroph, it was demonstrated that the C3/C4 interconversion reactions, previously thought to be side reactions of little relevance to core metabolism, are critical to the ultimate values of growth rate and yield. This new insight now provides targets for strain engineering towards either maximum growth rate, or maximum yield. For the RuMP cycle methanotroph, it was determined first, that contrary to decades of assumptions in the literature, the Type I methanotroph studied here operates a complete, oxidative TCA cycle. That finding changes the entire metabolic network balance, especially with regards to NADH generation, and this knowledge is essential for generating accurate predictive metabolic models. Second, it was determined that the partial serine cycle present in Type I methanotrophs does not play a significant role during growth on methane. However, it was discovered that it does play a role during growth on methanol. Growth on methanol was discovered to involve a substantially rearranged metabolic network compared to methane, in complete contrast to literature expectations. In this case, the TCA cycle is broken, NADH is generated mainly from formate oxidation, and flux shifts from the Embden-Meyer-Parnas pathway to the Entner-Douderoff pathway. In addition, substantial carbon is redirected to synthesis of glycogen and excretion of formate. We have concluded that both metabolic flux analysis and metabolomics are extremely valuable tools in understanding the metabolic network of methylotrophs, and their use has corrected metabolic misunderstanding that has been in the literature for decades. These methods must be tailored for the C1 assimilation system, and the results presented in this thesis demonstrate an approach for the two main types of methylotrophs. These new techniques are now ready to use for investigating other methylotrophs in the future, and to serve as important tools for future metabolic engineering of methylotrophs for biotechnology applications.
