Micro And Nanotechnologies In Engineering Stem Cells And Tissues


Micro And Nanotechnologies In Engineering Stem Cells And Tissues
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Micro And Nanotechnologies In Engineering Stem Cells And Tissues


Micro And Nanotechnologies In Engineering Stem Cells And Tissues
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Author : Murugan Ramalingam
language : en
Publisher: John Wiley & Sons
Release Date : 2013-05-10

Micro And Nanotechnologies In Engineering Stem Cells And Tissues written by Murugan Ramalingam and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-05-10 with Science categories.


A cutting-edge look at the application of micro and nanotechnologies in regenerative medicine The area at the interface of micro/nanotechnology and stem cells/tissue engineering has seen an explosion of activity in recent years. This book provides a much-needed overview of these exciting developments, covering all aspects of micro and nanotechnologies, from the fundamental principles to the latest research to applications in regenerative medicine. Written and edited by the top researchers in the field, Micro and Nanotechnologies in Engineering Stem Cells and Tissues describes advances in material systems along with current techniques available for cell, tissue, and organ studies. Readers will gain tremendous insight into the state of the art of stem cells and tissue engineering, and learn how to use the technology in their own research or clinical trials. Coverage includes: Technologies for controlling or regulating stem cell and tissue growth Various engineering approaches for stem cell, vascular tissue, and bone regeneration The design and processing of biocompatible polymers and other biomaterials Characterization of the interactions between cells and biomaterials Unrivaled among books of this kind, Micro and Nanotechnologies in Engineering Stem Cells and Tissues is the ultimate forward-looking reference for researchers in numerous disciplines, from engineering and materials science to biomedicine, and for anyone wishing to understand the trends in this transformative field.



Tissue And Organ Regeneration


Tissue And Organ Regeneration
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Author : Lijie Grace Zhang
language : en
Publisher: CRC Press
Release Date : 2016-04-19

Tissue And Organ Regeneration written by Lijie Grace Zhang and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-04-19 with Medical categories.


Tissue engineering aims to develop biological substitutes that restore, maintain, or improve damaged tissue and organ functionality. To date, numerous stem cells and biomaterials have been explored for a variety of tissue and organ regeneration. The challenge for existing stem cell–based techniques is that current therapies lack controlled environments that are crucial for regulating stem cell engraftment and differentiation in vivo, because stem cells are rather sensitive to even minute changes in their environment. Micro- and nanotechnology hold great potential to fabricate biomimetic spatiotemporally controlled scaffolds as well as control stem cell behavior and fate by micro- and nanoscale cues. This book presents the latest micro- and nanotechnologies used to manipulate stem cell behaviors, which is a critical area for regenerative medicine. Moreover, it covers and details cutting-edge research in nano- and microfabrication techniques and biomaterials for the regeneration of various tissues and organs, such as bone, cartilage, craniofacial, osteochondral, muscle, bladder, cardiac, and vascular tissues.



Micro And Nanoengineering Of The Cell Surface


Micro And Nanoengineering Of The Cell Surface
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Author : Jeffrey M Karp
language : en
Publisher: William Andrew
Release Date : 2014-05-30

Micro And Nanoengineering Of The Cell Surface written by Jeffrey M Karp and has been published by William Andrew this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-05-30 with Science categories.


Micro- and Nanoengineering of the Cell Surface explores the direct engineering of cell surfaces, enabling materials scientists and chemists to manipulate or augment cell functions and phenotypes. The book is accessible for readers across industry, academia, and in clinical settings in multiple disciplines, including materials science, engineering, chemistry, biology, and medicine. Written by leaders in the field, it covers numerous cell surface engineering methods along with their current and potential applications in cell therapy, tissue engineering, biosensing, and diagnosis. The interface of chemistry, materials science, and biology presents many opportunities for developing innovative tools to diagnose and treat various diseases. However, cell surface engineering using chemistry and materials science approaches is a new and diverse field. This book provides a full coverage of the subject, introducing the fundamentals of cell membrane biology before exploring the key application areas. Demystifies the direct engineering of cell surfaces, enabling materials scientists and chemists to manipulate or augment cell functions and phenotypes Provides a toolkit of micro- and nanoengineering approaches to the manipulation of the cell surface Unlocks the potential of cell surface manipulation for a range of new applications in the fields of in vitro research, cell therapy, tissue engineering, biosensing, and diagnostics



Nanotechnology And Regenerative Medicine


Nanotechnology And Regenerative Medicine
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Author : Maria H. Santana
language : en
Publisher: Academic Press
Release Date : 2022-11-24

Nanotechnology And Regenerative Medicine written by Maria H. Santana and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-11-24 with Science categories.


"Cell niches are present in several human body tissues as a dynamic microenvironment essential to modulate stem cells’ behavior in health, under injury, and in regenerative processes. The interplay between stem cells and their niche is necessary for sustaining tissues. The extracellular matrix (ECM) is the crucial component of the stem cell. It defines the architectural space, physical binding to the cell membrane, and interactions with the neighborhood cells and supports physical stress. Domains with nano or micrometric sizes define the surface and topology of the ECM, mediating cell interactions and macrophage recruitment to injured sites. Over the last two decades, the integration of biomedicine with other engineering and biomaterial sciences promoted the development of nanotechnology and regenerative medicine toward mimicking the specialized stem cell niches to treat diseases with less invasive and efficient therapies. Innovative approaches in nanotechnology, such as targeting the immunological system, transporting drugs across blood–brain/BBB and blood–retinal barriers/BRB, directing active moiety to specific disease location/organs, encapsulation of multiple components, and promoting signalization and pathway-specific surfaces for cell interactions and growth, are indeed promising. On the other side, developments of biomaterial scaffolds to mimic the cell niches for interactions with stem cells in vitro or in vivo have tremendous potential. The three-dimensional printing technology offers a base for a wide array of applications, for example, developing tissue constructs, mimetic organs, organoids, and organ-on-a-chip, thus avoiding the differences between animal model species and humans. Aiming closer to the natural environments, fresh autologous products from the blood, such as platelet-rich plasma (PRP), contain platelets and leukocytes, providing growth factors, cytokines, and proteins for the resident stem cells in the stages of regeneration. PRP also provides pain relief, reducing disabilities in elderly or diseased people. This book brings thought-provoking multidisciplinary topics on the diverse aspects of basic and applied sciences. The prime focus of the compilation is to understand the challenges researchers encounter in combining nanotechnology and regenerative medicine, ultimately integrating both disciplines for the benefit of the patient and offering them a ray of hope to be cured. Presents multi-disciplined knowledge on bench-to-bedside application of nanotechnology in regenerative medicines Highlights the fundamentals, frontiers, limitations, and challenges faced by regenerative medicines Exhibits synergy of biotechnology, nanomedicine, biomedicine, chemical-material engineering, pharmaceutical technology, and applied medical sciences in success of regenerative medicines



Handbook Of Research On Nano Drug Delivery And Tissue Engineering


Handbook Of Research On Nano Drug Delivery And Tissue Engineering
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Author : Rajakumari Rajendran
language : en
Publisher: CRC Press
Release Date : 2022-03-10

Handbook Of Research On Nano Drug Delivery And Tissue Engineering written by Rajakumari Rajendran and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-03-10 with Science categories.


With contributions from leading researchers in the nanomedicine field from industry, academia, and government and private research institutions across the globe, the volume provides an up-to-date report on topical issues in nano-drug delivery and nanotechnological approaches to tissue engineering. The volume offers research on a variety of diverse nano-based drug delivery systems along with discussions of their efficacy, safety, toxicology, and applications for different purposes. Focusing on nanotechnology approaches to tissue engineering, this volume considers the use of hydrogel systems, nanoceria and micro- and nano-structured biomaterials for bone tissue engineering, mesenchymal stem cells, and more.



Micro And Nanoengineering Of The Cell Microenvironment


Micro And Nanoengineering Of The Cell Microenvironment
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Author : Ali Khademhosseini
language : en
Publisher: Artech House
Release Date : 2008

Micro And Nanoengineering Of The Cell Microenvironment written by Ali Khademhosseini and has been published by Artech House this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with Science categories.


Supported with 140 illustrations, the volume exhaustively covers the micro- and nano-system technologies involved in developing cell-based bioengineering applications. You get full details on efforts to engineer the soluble and insoluble cell microenvironments, including the latest advances in microfluidic devices, surface patterning, 3D scaffolds, and techniques for engineering cellular mechanical properties and topography.



Nanotechnology Applications For Tissue Engineering


Nanotechnology Applications For Tissue Engineering
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Author : Sabu Thomas
language : en
Publisher: William Andrew
Release Date : 2015-01-03

Nanotechnology Applications For Tissue Engineering written by Sabu Thomas and has been published by William Andrew this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-01-03 with Technology & Engineering categories.


Tissue engineering involves seeding of cells on bio-mimicked scaffolds providing adhesive surfaces. Researchers though face a range of problems in generating tissue which can be circumvented by employing nanotechnology. It provides substrates for cell adhesion and proliferation and agents for cell growth and can be used to create nanostructures and nanoparticles to aid the engineering of different types of tissue. Written by renowned scientists from academia and industry, this book covers the recent developments, trends and innovations in the application of nanotechnologies in tissue engineering and regenerative medicine. It provides information on methodologies for designing and using biomaterials to regenerate tissue, on novel nano-textured surface features of materials (nano-structured polymers and metals e.g.) as well as on theranostics, immunology and nano-toxicology aspects. In the book also explained are fabrication techniques for production of scaffolds to a series of tissue-specific applications of scaffolds in tissue engineering for specific biomaterials and several types of tissue (such as skin bone, cartilage, vascular, cardiac, bladder and brain tissue). Furthermore, developments in nano drug delivery, gene therapy and cancer nanotechonology are described. The book helps readers to gain a working knowledge about the nanotechnology aspects of tissue engineering and will be of great use to those involved in building specific tissue substitutes in reaching their objective in a more efficient way. It is aimed for R&D and academic scientists, lab engineers, lecturers and PhD students engaged in the fields of tissue engineering or more generally regenerative medicine, nanomedicine, medical devices, nanofabrication, biofabrication, nano- and biomaterials and biomedical engineering. Provides state-of-the-art knowledge on how nanotechnology can help tackling known problems in tissue engineering Covers materials design, fabrication techniques for tissue-specific applications as well as immunology and toxicology aspects Helps scientists and lab engineers building tissue substitutes in a more efficient way



Nanotechnology In Tissue Engineering And Regenerative Medicine


Nanotechnology In Tissue Engineering And Regenerative Medicine
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Author : Ketul Popat
language : en
Publisher: CRC Press
Release Date : 2010-11-22

Nanotechnology In Tissue Engineering And Regenerative Medicine written by Ketul Popat and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-11-22 with Mathematics categories.


Although nanotechnology applied to medicine has a potentially huge impact on drug delivery and tissue engineering, significant challenges need to be resolved before clinically viable nanomedicine or nanobiomedicine therapies will be available. Skillfully edited, with contributions from an expert panel of researchers, Nanotechnology in Tissue Engineering and Regenerative Medicine discusses the use of nanotechnology for medical applications with a focus on its use for drug delivery and tissue engineering. It sheds light on the challenges facing the field and examines cutting-edge research that may provide solutions. Topics covered include: Patterning of biomimetic substrates with AFM lithography, primarily focusing on DPN Nanotemplating polymer melts Nanotechnology-based approaches in the treatment of injuries to tendons and ligaments Progress in the use of electrospinning processing techniques for fabricating nanofiber scaffolds for neural applications Nanotopography techniques for tissue-engineered scaffolds and the effects of nanotopography on cells and tissues Vertically aligned TiO2 nanotube surface structuring for optimization of Ti implants utilizing nanotechnology Applications originating from the harmony of nanotechnology to biological systems, especially for the regeneration in the nervous system Current understanding of the mechanisms by which cells sense nano-scale structure at the molecular level and how this understanding can be useful in developing novel antifouling materials While there are books available on tissue engineering and nanotechnology and others about regenerative medicine, most do not comprehensively cover applications of nanotechnology to both these areas. Focusing chiefly on drug delivery, tissue engineering, and regenerative medicine, the book uses an application-based approach to relate laboratory-based research to the development of technologies that can be readily adaptable to an industrial environment.



Biomaterials And Nanotechnology For Tissue Engineering


Biomaterials And Nanotechnology For Tissue Engineering
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Author : Swaminathan Sethuraman
language : en
Publisher: CRC Press
Release Date : 2016-10-26

Biomaterials And Nanotechnology For Tissue Engineering written by Swaminathan Sethuraman and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-10-26 with Medical categories.


Nanotechnology and high-end characterization techniques have highlighted the importance of the material choice for the success of tissue engineering. A paradigm shift has been seen from conventional passive materials as scaffolds to smart multi-functional materials that can mimic the complex intracellular milieu more effectively. This book presents a detailed overview of the rationale involved in the choice of materials for regeneration of different tissues and the future directions in this fascinating area of materials science with specific chapters on regulatory challenges & ethics; tissue engineered medical products.



Microscale Technologies For Cell Engineering


Microscale Technologies For Cell Engineering
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Author : Ankur Singh
language : en
Publisher: Springer
Release Date : 2015-08-19

Microscale Technologies For Cell Engineering written by Ankur Singh and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-08-19 with Technology & Engineering categories.


This book offers readers cutting-edge research at the interface of polymer science and engineering, biomedical engineering, materials science, and biology. State-of-the-art developments in microscale technologies for cell engineering applications are covered, including technologies relevant to both pluripotent and adult stem cells, the immune system, and somatic cells of the animal and human origin. This book bridges the gap in the understanding of engineering biology at multiple length scale, including microenvironmental control, bioprocessing, and tissue engineering in the areas of cardiac, cartilage, skeletal, and vascular tissues, among others. This book also discusses unique, emerging areas of micropatterning and three-dimensional printing models of cellular engineering, and contributes to the better understanding of the role of biophysical factors in determining the cell fate. Microscale Technologies for Cell Engineering is valuable for bioengineers, biomaterial scientists, tissue engineers, clinicians, immunoengineers, immunologists and stem cell biologists, as it offers a review of the current cutting-edge cell engineering research at multiple length scale and will be valuable in developing new strategies for efficient scale-up and clinical translation.