Microbicides For Prevention Of Hiv Infection
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Microbicides For Prevention Of Hiv Infection
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Author : Jeremy Nuttall
language : en
Publisher: Springer
Release Date : 2014-09-06
Microbicides For Prevention Of Hiv Infection written by Jeremy Nuttall and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-09-06 with Medical categories.
One of the most promising new approaches for the prevention of HIV transmission, particularly for developing countries, involves topical, self-administered products known as microbicides. The development of microbicides is a long and complicated process, and this volume provides an overview of all the critical areas, from the selection of appropriate candidate molecules and their formulation, preclinical and clinical testing for safety and efficacy, strategies for product registration and finally, issues associated with product launch, distribution and access. The book will prove valuable to both those working in the field and all others who are interested in learning more about this product class, which has the potential to significantly impact the future of this devastating epidemic.
Drug Delivery And Development Of Anti Hiv Microbicides
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Author : José das Neves
language : en
Publisher: CRC Press
Release Date : 2014-10-16
Drug Delivery And Development Of Anti Hiv Microbicides written by José das Neves and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-10-16 with Medical categories.
The worldwide impact of HIV/AIDS is well recognized. This book provides for the first time a thorough and critical overview of current aspects, recent developments, and trends in the formulation and drug delivery concerning anti-HIV microbicides by leading scientists in the field. Additionally, pertinent regulatory aspects and socioeconomical issues related to the subject are discussed. In the absence of a cure, prophylaxis represents a cornerstone in the battle against infection. One promising strategy comprises the use around the time of sexual intercourse of vaginal/rectal products containing antiviral compounds, termed microbicides. It is now recognized that specific development of drug dosage forms and/or drug delivery systems is an indispensable aspect for the success of microbicides. Different groups strived over the last decade to optimize the biophysical and technological performance of traditional dosage forms (gels, tablets, and suppositories) to fulfill the specificities of microbicides use, without neglecting users’ preferences and affordability issues. Moreover, new formulation approaches, such as vaginal rings and films, nanotechnology-based systems, stimuli-sensitive formulations, targeted drug delivery systems, among others have been proposed and are currently undergoing pre-clinical or even clinical testing.
The Development Of Microbicides
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Author : Christopher J. Elias
language : en
Publisher:
Release Date : 1993
The Development Of Microbicides written by Christopher J. Elias and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993 with AIDS vaccines categories.
Hiv Prevention
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Author : Kenneth H. Mayer
language : en
Publisher: Academic Press
Release Date : 2009-03-13
Hiv Prevention written by Kenneth H. Mayer and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-03-13 with Medical categories.
HIV/AIDS continues to be the pandemic of our times and there has not been a comprehensive medically based AIDS prevention book published in the last 5 years. It is estimated that 36 to 45 million people including 2-3 million children already are infected worldwide and an additional 4-7 million more are infected each year. There are about 6,000 new infections daily and about 12 million AIDS orphans. People receiving AIDS treatments feel well and have no detectable viral load, but still can infect others. And even when a vaccine is found, it will take many years before it can be administered across the developing world. Discusses all aspects of AIDS prevention, from epidemiology, molecular immunology and virology to the principles of broad-based public health prevention interventions Special focus on the array of interventions that have been proven effective through rigorous study Identifies new trends in HIV/AID epidemiology and their impact on creating and implementing prevention interventions Incorporates virology, biology, infectious diseases, vaccinology, microbicides and research methodologies into AIDS prevention
Microbicides For Hiv Prevention
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Author : Joint United Nations Programme on HIV/AIDS.
language : en
Publisher:
Release Date : 1998
Microbicides For Hiv Prevention written by Joint United Nations Programme on HIV/AIDS. and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998 with Anti-infective agents categories.
Bioethical Challenges In New Hiv Prevention Technologies
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Author : Calvin Gwandure
language : en
Publisher: Xlibris Corporation
Release Date : 2018-05-23
Bioethical Challenges In New Hiv Prevention Technologies written by Calvin Gwandure and has been published by Xlibris Corporation this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-05-23 with Education categories.
Ruth Gwandure earned her master of science degree in medicine (bioethics and law) from the University of the Witwatersrand, South Africa. Her research and consulting fields include bioethics, health law, environmental bioethics, research ethics, HIV and AIDS, ethics and law, clinical ethics, and HIV counselling and testing in schools. Calvin Gwandure has a PhD in psychology. He graduated from Nelson Mandela University, South Africa. His research and consulting fields include HIV and AIDS prevention, new HIV prevention technologies, HIV risk behavior, and group behavior. Clinical trials on HIV and AIDS prevention face challenges associated with infection of participants with HIV and sexually transmitted infections. Participants also experience adverse events associated with voluntary medical male circumcision and the use of microbicides and vaccines in clinical trials. The results obtained from clinical trials investigating the efficacy of microbicides and vaccines in preventing HIV infection are disappointing, but there is hope that one day a breakthrough could be made. Clinical trials on voluntary medical male circumcision and preexposure prophylaxis have shown positive results that warranted approval by the US Food and Drug Administration (FDA) and the World Health Organization (WHO). The major challenge experienced in new HIV prevention clinical trials that are underway and in approved interventions that are being scaled up apparently relates to HIV incidence that threatens the social value and scientific validity of the interventions. Paradoxically, the clinical trials and scale-up interventions have become the new sources of HIV infection although the hypothesized benefit to be realized in the end is conceptualized as outweighing the current risks involved.
No Time To Lose
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Author : Institute of Medicine
language : en
Publisher: National Academies Press
Release Date : 2001-03-02
No Time To Lose written by Institute of Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-03-02 with Medical categories.
The United States has spent two productive decades implementing a variety of prevention programs. While these efforts have slowed the rate of infection, challenges remain. The United States must refocus its efforts to contain the spread of HIV and AIDS in a way that would prevent as many new HIV infections as possible. No Time to Lose presents the Institute of Medicine's framework for a national prevention strategy.
Biomedical Advances In Hiv Prevention
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Author : Lisa A. Eaton
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-10-08
Biomedical Advances In Hiv Prevention written by Lisa A. Eaton and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-08 with Medical categories.
Biomedical Advances in HIV Prevention: Social and Behavioral Perspectives Lisa A. Eaton and Seth C. Kalichman, editors Three decades into the epidemic, a great deal is known about HIV and its transmission, more people are living with the disease, and the virus is no longer seen as a death sentence. But new people continue to be infected with HIV each year, making prevention strategies that are medically effective and behaviorally engaging as urgent a priority as ever. Biomedical Advances in HIV Prevention: Social and Behavioral Perspectives assembles the latest improvements, barriers to implementation, and possibilities for--and challenges to--future progress. Innovations such as pre-exposure prophylaxis (antiretroviral regimens for the high-risk uninfected) and treatment as prevention (early use of ART to reduce infectiousness of new patients) are examined, as are current findings on ongoing prevention and treatment concerns. Contributors illuminate the complex realities entailing adherence, pointing out technological, behavioral, and cultural roadblocks as well as opportunities to significantly reduce infection rates. Detailed up-to-the-minute coverage includes: Prevention services for persons living with HIV Adherence to HIV treatment as prevention and pre-exposure prophylaxis Advocating for rectal microbicides and safe lubricants Mental health and substance use in the scale-up of HIV prevention Risk compensation in response to HIV prevention Implementing biomedical HIV prevention advances: reports from South Africa, Uganda, Australia, Thailand, United States, Ecuador, and Peru Researchers, practitioners, and policy makers working in the fields of HIV/AIDS and public health will look toward Biomedical Advances in HIV Prevention: Social and Behavioral Perspectives as both a means for developing and assessing current programs and a blueprint for the next generation of prevention efforts.
Trends In Basic And Therapeutic Options In Hiv Infection
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Author : Bartholomew Ibeh
language : en
Publisher: BoD – Books on Demand
Release Date : 2015-09-02
Trends In Basic And Therapeutic Options In Hiv Infection written by Bartholomew Ibeh and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-09-02 with Medical categories.
The past decade has seen several changes in HIV prevention, transmission and therapeutic interventions to end the scourge. This book is a collection of expert assays on various aspects of HIV prevention, bioresource deployment, microbicides, host antiviral proteins, antiviral drug responses and novel treatment strategies for which there is evident need for scientific focus and review of the current trend. A visible objective of the book is to provide a wider readership of scientist, clinicians, social workers/HIV caregivers, immunologist, postgraduate students, trainers and vaccine developers an informative and multidisciplinary approach to HIV treatment and intervention strategy by presenting current trends in the development of therapeutic options and its attendant challenges. Practical and informative, the book provides state-of-the-art information on dynamics of HIV distribution, transmission, therapeutic measures and functional cure.
Microbicides 2000
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Author :
language : en
Publisher:
Release Date : 2001
Microbicides 2000 written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001 with AIDS (Disease) categories.