Modeling And Control In Biomedical Systems

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Modelling And Control In Biomedical Systems

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Author : Claudio Cobelli
language : en
Publisher: Pergamon
Release Date : 1989

Modelling And Control In Biomedical Systems written by Claudio Cobelli and has been published by Pergamon this book supported file pdf, txt, epub, kindle and other format this book has been release on 1989 with Medical categories.

Hardbound. This volume provides a complete and up-to-date review of the recent developments and trends relating to modelling and control in biomedical systems in research, diagnosis and therapy. Focus is placed on methodological issues relevant to modelling and control as well as to the various physiological systems of the organism visited from a control viewpoint. Contains 98 papers.

Signals And Systems In Biomedical Engineering

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Author : Suresh R. Devasahayam
language : en
Publisher: Springer Science & Business Media
Release Date : 2000

Signals And Systems In Biomedical Engineering written by Suresh R. Devasahayam and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000 with Mathematics categories.

CD-ROM includes programs for teaching signal processing in installable form.

Modeling And Simulation In Biomedical Engineering Applications In Cardiorespiratory Physiology

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Author : Willem L. van Meurs
language : en
Publisher: McGraw Hill Professional
Release Date : 2011-08-07

Modeling And Simulation In Biomedical Engineering Applications In Cardiorespiratory Physiology written by Willem L. van Meurs and has been published by McGraw Hill Professional this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-08-07 with Technology & Engineering categories.

THEORY AND PRACTICE OF MODELING AND SIMULATING HUMAN PHYSIOLOGY Written by a coinventor of the Human Patient Simulator (HPS) and past president of the Society in Europe for Simulation Applied to Medicine (SESAM), Modeling and Simulation in Biomedical Engineering: Applications in Cardiorespiratory Physiology is a compact and consistent introduction to this expanding field. The book divides the modeling and simulation process into five manageable steps--requirements, conceptual models, mathematical models, software implementation, and simulation results and validation. A framework and a basic set of deterministic, continuous-time models for the cardiorespiratory system are provided. This timely resource also addresses advanced topics, including sensitivity analysis and setting model requirements as part of an encompassing simulation and simulator design. Practical examples provide you with the skills to evaluate and adapt existing physiologic models or create new ones for specific applications. Coverage includes: Signals and systems Model requirements Conceptual models Mathematical models Software implementation Simulation results and model validation Cardiorespiratory system model Circulation Respiration Physiologic control Sensitivity analysis of a cardiovascular model Design of model-driven acute care training simulators “Uniquely qualified to author such a text, van Meurs is one of the original developers of CAE Healthcare’s Human Patient Simulator (HPS). ...His understanding of mathematics, human physiology, pharmacology, control systems, and systems engineering, combined with a conversational writing style, results in a readable text. ...The ample illustrations and tables also break up the text and make reading the book easier on the eyes. ...concise yet in conversational style, with real-life examples. This book is highly recommended for coursework in physiologic modeling and for all who are interested in simulator design and development. The book pulls all these topics together under one cover and is an important contribution to biomedical literature.” --IEEE Pulse, January 2014 “This book is written by a professional engineer who is unique in that he seems to have a natural understanding of 3 key areas as follows: the hardware involved with simulators, human physiology, and mathematical modeling. Willem van Meurs is one of the inventors of the model-driven human patient simulator (HPS), and so, he is very qualified to write this book. The book is written in a clear way, using the first person throughout, in a conversational manner, with a style that involves posing questions and answering them in subsequent text. ...The book starts with a very useful introduction and background chapter, setting out the scene for the rest of the book. ...I have used his book in enhancing my own talks and understanding human patient simulation and can strongly recommend it.” --Simulation in Healthcare December, 2012 Reviewed by Mark A. Tooley, Ph.D., Department of Medical Physics and Bioengineering, Royal United Hospital, Combe Park, Bath, UK.

Modelling Optimization And Control Of Biomedical Systems

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Author : Efstratios N. Pistikopoulos
language : en
Publisher: John Wiley & Sons
Release Date : 2018-01-09

Modelling Optimization And Control Of Biomedical Systems written by Efstratios N. Pistikopoulos and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-01-09 with Technology & Engineering categories.

Shows the newest developments in the field of multi-parametric model predictive control and optimization and their application for drug delivery systems This book is based on the Modelling, Control and Optimization of Biomedical Systems (MOBILE) project, which was created to derive intelligent computer model-based systems for optimization of biomedical drug delivery systems in the cases of diabetes, anaesthesia, and blood cancer. These systems can ensure reliable and fast calculation of the optimal drug dosage without the need for an online computer—while taking into account the specifics and constraints of the patient model, flexibility to adapt to changing patient characteristics and incorporation of the physician’s performance criteria, and maintaining the safety of the patients. Modelling Optimization and Control of Biomedical Systems covers: mathematical modelling of drug delivery systems; model analysis, parameter estimation, and approximation; optimization and control; sensitivity analysis & model reduction; multi-parametric programming and model predictive control; estimation techniques; physiologically-based patient model; control design for volatile anaesthesia; multiparametric model based approach to intravenous anaesthesia; hybrid model predictive control strategies; Type I Diabetes Mellitus; in vitro and in silico block of the integrated platform for the study of leukaemia; chemotherapy treatment as a process systems application; and more. Introduces readers to the Modelling, Control and Optimization of Biomedical Systems (MOBILE) project Presents in detail the theoretical background, computational tools, and methods that are used in all the different biomedical systems Teaches the theory for multi-parametric mixed-integer programming and explicit optimal control of volatile anaesthesia Provides an overview of the framework for modelling, optimization, and control of biomedical systems This book will appeal to students, researchers, and scientists working on the modelling, control, and optimization of biomedical systems and to those involved in cancer treatment, anaesthsia, and drug delivery systems.

Automatic Control Systems In Biomedical Engineering

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Author : J. Fernández de Cañete
language : en
Publisher: Springer
Release Date : 2018-03-12

Automatic Control Systems In Biomedical Engineering written by J. Fernández de Cañete and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-03-12 with Technology & Engineering categories.

This book presents the fundamental principles and challenges encountered in the control of biomedical systems, providing practical solutions and suggesting alternatives. The perspective of the text is based on the system behaviour in the time domain both linear and non-linear, continuous and discrete, helping the reader to be able to interpret the physical significance of mathematical results during control system analysis and design focusing on biomedical engineering applications. Interactive learning is promoted, endowing students with the ability to change parameters and conditions during the simulation and see the effects of these changes, by using interactive MATLAB and SIMULINK software tools, also presenting realistic problems in order to analyse, design and develop automatic control systems. The text is also complemented with MATLAB and SIMULINK exercise files solved to aid students to focus on the fundamental concepts treated throughout the book, following a new pedagogical approach distinct from the classical one whereby fundamental control concepts are introduced together with adequate software tools in order to gain insight on the biomedical engineering control problems. The book is suitable for second or third-year undergraduate students who will find the illustrative examples particularly useful to their studies of control system design and implementation. Lecturers in the control field will find the computer aided design approach as an alternative to teaching the fundamental concepts of feedback analogic and digital control.

Dynamic Modeling And Control Of Engineering Systems

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Author : Bohdan T. Kulakowski
language : en
Publisher: Cambridge University Press
Release Date : 2014-04-30

Dynamic Modeling And Control Of Engineering Systems written by Bohdan T. Kulakowski and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-04-30 with Technology & Engineering categories.

This textbook is ideal for an undergraduate course in Engineering System Dynamics and Controls. It is intended to provide the reader with a thorough understanding of the process of creating mathematical (and computer-based) models of physical systems. The material is restricted to lumped parameter models, which are those models in which time is the only independent variable. It assumes a basic knowledge of engineering mechanics and ordinary differential equations. The new edition has expanded topical coverage and many more new examples and exercises.

Modeling Biological Systems

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Author : James W. Haefner
language : en
Publisher: Springer Science & Business Media
Release Date : 2005-05-06

Modeling Biological Systems written by James W. Haefner and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-05-06 with Science categories.

I Principles 1 1 Models of Systems 3 1. 1 Systems. Models. and Modeling . . . . . . . . . . . . . . . . . . . . 3 1. 2 Uses of Scientific Models . . . . . . . . . . . . . . . . . . . . . . . . 4 1. 3 Example: Island Biogeography . . . . . . . . . . . . . . . . . . . . . 6 1. 4 Classifications of Models . . . . . . . . . . . . . . . . . . . . . . . . 10 1. 5 Constraints on Model Structure . . . . . . . . . . . . . . . . . . . . . 12 1. 6 Some Terminology . . . . . . . . . . . . . . . . . . . . . . . . . . . 12 1. 7 Misuses of Models: The Dark Side . . . . . . . . . . . . . . . . . . . 13 1. 8 Exercises . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 15 2 The Modeling Process 17 2. 1 Models Are Problems . . . . . . . . . . . . . . . . . . . . . . . . . . 17 2. 2 Two Alternative Approaches . . . . . . . . . . . . . . . . . . . . . . 18 2. 3 An Example: Population Doubling Time . . . . . . . . . . . . . . . . 24 2. 4 Model Objectives . . . . . . . . . . . . . . . . . . . . . . . . . . . . 28 2. 5 Exercises . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 30 3 Qualitative Model Formulation 32 3. 1 How to Eat an Elephant . . . . . . . . . . . . . . . . . . . . . . . . . 32 3. 2 Forrester Diagrams . . . . . . . . . . . . . . . . . . . . . . . . . . . 33 3. 3 Examples . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 36 3. 4 Errors in Forrester Diagrams . . . . . . . . . . . . . . . . . . . . . . 44 3. 5 Advantages and Disadvantages of Forrester Diagrams . . . . . . . . . 44 3. 6 Principles of Qualitative Formulation . . . . . . . . . . . . . . . . . . 45 3. 7 Model Simplification . . . . . . . . . . . . . . . . . . . . . . . . . . 47 3. 8 Other Modeling Problems . . . . . . . . . . . . . . . . . . . . . . . . 49 viii Contents . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3. 9 Exercises 53 4 Quantitative Model Formulation: I 4. 1 From Qualitative to Quantitative . . . . . . . . . . . . . . . . . Finite Difference Equations and Differential Equations 4. 2 . . . . . . . . . . . . . . . . 4. 3 Biological Feedback in Quantitative Models . . . . . . . . . . . . . . . . . . . . . . . . . . 4. 4 Example Model . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4. 5 Exercises 5 Quantitative Model Formulation: I1 81 . . . . . . . . . . . . . . . . . . . . . . . . . . . 5. 1 Physical Processes 81 . . . . . . . . . . . . . . . 5. 2 Using the Toolbox of Biological Processes 89 . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5. 3 Useful Functions 96 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5. 4 Examples 102 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5. 5 Exercises 104 6 Numerical Techniques 107 . . . . . . . . . . . . . . . . . . . . . . . 6. 1 Mistakes Computers Make 107 . . . . . . . . . . . . . . . . . . . . . . . . . . 6. 2 Numerical Integration 110 . . . . . . . . . . . . . . . . 6. 3 Numerical Instability and Stiff Equations 115 . . . . . . . . . . . . . .

Nonlinear Dynamic Modeling Of Physiological Systems

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Author : Professor Vasilis Z. Marmarelis
language : en
Publisher: John Wiley & Sons
Release Date : 2004-09-03

Nonlinear Dynamic Modeling Of Physiological Systems written by Professor Vasilis Z. Marmarelis and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-09-03 with Medical categories.

The study of nonlinearities in physiology has been hindered by the lack of effective ways to obtain nonlinear dynamic models from stimulus-response data in a practical context. A considerable body of knowledge has accumulated over the last thirty years in this area of research. This book summarizes that progress, and details the most recent methodologies that offer practical solutions to this daunting problem. Implementation and application are discussed, and examples are provided using both synthetic and actual experimental data. This essential study of nonlinearities in physiology apprises researchers and students of the latest findings and techniques in the field.

Computational And Mathematical Models In Biology

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Author : Carla M.A. Pinto
language : en
Publisher: Springer Nature
Release Date : 2023-12-08

Computational And Mathematical Models In Biology written by Carla M.A. Pinto and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-12-08 with Mathematics categories.

This book provides the most valuable and updated research on computational and mathematical models in biological systems from influential researchers around the world and contributes to the development of future research guidelines in this topic. Topics include (but are not limited to): modeling infectious and dynamic diseases; regulation of cell function; biological pattern formation; biological networks; tumor growth and angiogenesis; complex biological systems; Monte Carlo methods; Control theory, optimization and their applications

Xiii Mediterranean Conference On Medical And Biological Engineering And Computing 2013

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Author : Laura M. Roa Romero
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-10-01

Xiii Mediterranean Conference On Medical And Biological Engineering And Computing 2013 written by Laura M. Roa Romero and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-01 with Technology & Engineering categories.

The general theme of MEDICON 2013 is "Research and Development of Technology for Sustainable Healthcare". This decade is being characterized by the appearance and use of emergent technologies under development. This situation has produced a tremendous impact on Medicine and Biology from which it is expected an unparalleled evolution in these disciplines towards novel concept and practices. The consequence will be a significant improvement in health care and well-fare, i.e. the shift from a reactive medicine to a preventive medicine. This shift implies that the citizen will play an important role in the healthcare delivery process, what requires a comprehensive and personalized assistance. In this context, society will meet emerging media, incorporated to all objects, capable of providing a seamless, adaptive, anticipatory, unobtrusive and pervasive assistance. The challenge will be to remove current barriers related to the lack of knowledge required to produce new opportunities for all the society, while new paradigms are created for this inclusive society to be socially and economically sustainable, and respectful with the environment. In this way, these proceedings focus on the convergence of biomedical engineering topics ranging from formalized theory through experimental science and technological development to practical clinical applications.