Modeling And Simulation Theory And Practice
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Biopharmaceutics Modeling And Simulations
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Author : Kiyohiko Sugano
language : en
Publisher: John Wiley & Sons
Release Date : 2012-07-31
Biopharmaceutics Modeling And Simulations written by Kiyohiko Sugano and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-07-31 with Medical categories.
A comprehensive introduction to using modeling and simulation programs in drug discovery and development Biopharmaceutical modeling has become integral to the design and development of new drugs. Influencing key aspects of the development process, including drug substance design, formulation design, and toxicological exposure assessment, biopharmaceutical modeling is now seen as the linchpin to a drug's future success. And while there are a number of commercially available software programs for drug modeling, there has not been a single resource guiding pharmaceutical professionals to the actual tools and practices needed to design and test safe drugs. A guide to the basics of modeling and simulation programs, Biopharmaceutics Modeling and Simulations offers pharmaceutical scientists the keys to understanding how they work and are applied in creating drugs with desired medicinal properties. Beginning with a focus on the oral absorption of drugs, the book discusses: The central dogma of oral drug absorption (the interplay of dissolution, solubility, and permeability of a drug), which forms the basis of the biopharmaceutical classification system (BCS) The concept of drug concentration How to simulate key drug absorption processes The physiological and drug property data used for biopharmaceutical modeling Reliable practices for reporting results With over 200 figures and illustrations and a peerless examination of all the key aspects of drug research—including running and interpreting models, validation, and compound and formulation selection—this reference seamlessly brings together the proven practical approaches essential to developing the safe and effective medicines of tomorrow.
Simulation Modelling Practice And Theory
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Author : Evon M. O. Abu-Taieh
language : en
Publisher: Intechopen
Release Date : 2019
Simulation Modelling Practice And Theory written by Evon M. O. Abu-Taieh and has been published by Intechopen this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019 with Computers categories.
The influx of data in the world today needs analysis that no one method can handle. Some reports estimated the influx of data would reach 163 zitabytes by 2025, hence the need for simulation and modeling theory and practice. Simulation and modeling tools and techniques are most important in this day and age. While simulation carries the needed work, tools for visualizing the results help in the decision-making process. Simulation ranges from a simple queue to molecular dynamics, including seismic reliability analysis, structural integrity assessment, games, reliability engineering, and system safety. This book will introduce practitioners, researchers, and novice users to simulation and modeling, and to the world of imagination.
Process Modeling And Simulation For Chemical Engineers
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Author : Simant R. Upreti
language : en
Publisher: John Wiley & Sons
Release Date : 2017-04-05
Process Modeling And Simulation For Chemical Engineers written by Simant R. Upreti and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-04-05 with Technology & Engineering categories.
This book provides a rigorous treatment of the fundamental concepts and techniques involved in process modeling and simulation. The book allows the reader to: (i) Get a solid grasp of “under-the-hood” mathematical results (ii) Develop models of sophisticated processes (iii) Transform models to different geometries and domains as appropriate (iv) Utilize various model simplification techniques (v) Learn simple and effective computational methods for model simulation (vi) Intensify the effectiveness of their research Modeling and Simulation for Chemical Engineers: Theory and Practice begins with an introduction to the terminology of process modeling and simulation. Chapters 2 and 3 cover fundamental and constitutive relations, while Chapter 4 on model formulation builds on these relations. Chapters 5 and 6 introduce the advanced techniques of model transformation and simplification. Chapter 7 deals with model simulation, and the final chapter reviews important mathematical concepts. Presented in a methodical, systematic way, this book is suitable as a self-study guide or as a graduate reference, and includes examples, schematics and diagrams to enrich understanding. End of chapter problems with solutions and computer software available online at www.wiley.com/go/upreti/pms_for_chemical_engineers are designed to further stimulate readers to apply the newly learned concepts.
Discrete And Continuous Simulation
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Author : Susmita Bandyopadhyay
language : en
Publisher: CRC Press
Release Date : 2014-06-25
Discrete And Continuous Simulation written by Susmita Bandyopadhyay and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-06-25 with Mathematics categories.
When it comes to discovering glitches inherent in complex systems-be it a railway or banking, chemical production, medical, manufacturing, or inventory control system-developing a simulation of a system can identify problems with less time, effort, and disruption than it would take to employ the original. Advantageous to both academic and industria
Mosfet Models For Vlsi Circuit Simulation
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Author : Narain D. Arora
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Mosfet Models For Vlsi Circuit Simulation written by Narain D. Arora and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Computers categories.
Metal Oxide Semiconductor (MOS) transistors are the basic building block ofMOS integrated circuits (I C). Very Large Scale Integrated (VLSI) circuits using MOS technology have emerged as the dominant technology in the semiconductor industry. Over the past decade, the complexity of MOS IC's has increased at an astonishing rate. This is realized mainly through the reduction of MOS transistor dimensions in addition to the improvements in processing. Today VLSI circuits with over 3 million transistors on a chip, with effective or electrical channel lengths of 0. 5 microns, are in volume production. Designing such complex chips is virtually impossible without simulation tools which help to predict circuit behavior before actual circuits are fabricated. However, the utility of simulators as a tool for the design and analysis of circuits depends on the adequacy of the device models used in the simulator. This problem is further aggravated by the technology trend towards smaller and smaller device dimensions which increases the complexity of the models. There is extensive literature available on modeling these short channel devices. However, there is a lot of confusion too. Often it is not clear what model to use and which model parameter values are important and how to determine them. After working over 15 years in the field of semiconductor device modeling, I have felt the need for a book which can fill the gap between the theory and the practice of MOS transistor modeling. This book is an attempt in that direction.
Building Software For Simulation
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Author : James J. Nutaro
language : en
Publisher: John Wiley & Sons
Release Date : 2011-03-23
Building Software For Simulation written by James J. Nutaro and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-03-23 with Computers categories.
Building Software for Simulation A unique guide to the design and implementation of simulation software This book offers a concise introduction to the art of building simulation software, collecting the most important concepts and algorithms in one place. Written for both individuals new to the field of modeling and simulation as well as experienced practitioners, this guide explains the design and implementation of simulation software used in the engineering of large systems while presenting the relevant mathematical elements, concept discussions, and code development. The book approaches the topic from the perspective of Zeigler’s theory of modeling and simulation, introducing the theory’s fundamental concepts and showing how to apply them to engineering problems. Readers will learn five necessary skills for building simulations of complicated systems: Working with fundamental abstractions for simulating dynamic systems Developing basic simulation algorithms for continuous and discrete event models Combining continuous and discrete event simulations into a coherent whole Applying strategies for testing a simulation Understanding the theoretical foundations of the modeling constructs and simulation algorithms The central chapters of the book introduce, explain, and demonstrate the elements of the theory that are most important for building simulation tools. They are bracketed by applications to robotics, control and communications, and electric power systems; these comprehensive examples clearly illustrate how the concepts and algorithms are put to use. Readers will explore the design of object-oriented simulation programs, simulation using multi-core processors, and the integration of simulators into larger software systems. The focus on software makes this book particularly useful for computer science and computer engineering courses in simulation that focus on building simulators. It is indispensable reading for undergraduate and graduate students studying modeling and simulation, as well as for practicing scientists and engineers involved in the development of simulation tools.
Principles Of Modeling And Simulation
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Author : John A. Sokolowski
language : en
Publisher: John Wiley & Sons
Release Date : 2011-09-20
Principles Of Modeling And Simulation written by John A. Sokolowski and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-09-20 with Mathematics categories.
Explores wide-ranging applications of modeling and simulation techniques that allow readers to conduct research and ask "What if?" Principles of Modeling and Simulation: A Multidisciplinary Approach is the first book to provide an introduction to modeling and simulation techniques across diverse areas of study. Numerous researchers from the fields of social science, engineering, computer science, and business have collaborated on this work to explore the multifaceted uses of computational modeling while illustrating their applications in common spreadsheets. The book is organized into three succinct parts: Principles of Modeling and Simulation provides a brief history of modeling and simulation, outlines its many functions, and explores the advantages and disadvantages of using models in problem solving. Two major reasons to employ modeling and simulation are illustrated through the study of a specific problem in conjunction with the use of related applications, thus gaining insight into complex concepts. Theoretical Underpinnings examines various modeling techniques and introduces readers to two significant simulation concepts: discrete event simulation and simulation of continuous systems. This section details the two primary methods in which humans interface with simulations, and it also distinguishes the meaning, importance, and significance of verification and validation. Practical Domains delves into specific topics related to transportation, business, medicine, social science, and enterprise decision support. The challenges of modeling and simulation are discussed, along with advanced applied principles of modeling and simulation such as representation techniques, integration into the application infrastructure, and emerging technologies. With its accessible style and wealth of real-world examples, Principles of Modeling and Simulation: A Multidisciplinary Approach is a valuable book for modeling and simulation courses at the upper-undergraduate and graduate levels. It is also an indispensable reference for researchers and practitioners working in statistics, mathematics, engineering, computer science, economics, and the social sciences who would like to further develop their understanding and knowledge of the field.
Discrete Event Modeling And Simulation
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Author : Gabriel A. Wainer
language : en
Publisher: CRC Press
Release Date : 2018-09-03
Discrete Event Modeling And Simulation written by Gabriel A. Wainer and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-09-03 with Technology & Engineering categories.
Collecting the work of the foremost scientists in the field, Discrete-Event Modeling and Simulation: Theory and Applications presents the state of the art in modeling discrete-event systems using the discrete-event system specification (DEVS) approach. It introduces the latest advances, recent extensions of formal techniques, and real-world examples of various applications. The book covers many topics that pertain to several layers of the modeling and simulation architecture. It discusses DEVS model development support and the interaction of DEVS with other methodologies. It describes different forms of simulation supported by DEVS, the use of real-time DEVS simulation, the relationship between DEVS and graph transformation, the influence of DEVS variants on simulation performance, and interoperability and composability with emphasis on DEVS standardization. The text also examines extensions to DEVS, new formalisms, and abstractions of DEVS models as well as the theory and analysis behind real-world system identification and control. To support the generation and search of optimal models of a system, a framework is developed based on the system entity structure and its transformation to DEVS simulation models. In addition, the book explores numerous interesting examples that illustrate the use of DEVS to build successful applications, including optical network-on-chip, construction/building design, process control, workflow systems, and environmental models. A one-stop resource on advances in DEVS theory, applications, and methodology, this volume offers a sampling of the best research in the area, a broad picture of the DEVS landscape, and trend-setting applications enabled by the DEVS approach. It provides the basis for future research discoveries and encourages the development of new applications.
Circuit Simulation With Spice Opus
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Author : Tadej Tuma
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-06-23
Circuit Simulation With Spice Opus written by Tadej Tuma and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-06-23 with Technology & Engineering categories.
This book is a unique combination of a basic guide to general analog circuit simulation and a SPICE OPUS software manual, which may be used as a textbook or self-study reference. The book is divided into three parts: mathematical theory of circuit analysis, a crash course on SPICE OPUS, and a complete SPICE OPUS reference guide. All simulations as well as the free simulator software may be directly downloaded from the SPICE OPUS homepage: www.spiceopus.si. Circuit Simulation with SPICE OPUS is intended for a wide audience of undergraduate and graduate students, researchers, and practitioners in electrical and systems engineering, circuit design, and simulation development.
Modeling And Simulation Fundamentals
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Author : John A. Sokolowski
language : en
Publisher: John Wiley & Sons
Release Date : 2010-07-13
Modeling And Simulation Fundamentals written by John A. Sokolowski and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-07-13 with Mathematics categories.
An insightful presentation of the key concepts, paradigms, and applications of modeling and simulation Modeling and simulation has become an integral part of research and development across many fields of study, having evolved from a tool to a discipline in less than two decades. Modeling and Simulation Fundamentals offers a comprehensive and authoritative treatment of the topic and includes definitions, paradigms, and applications to equip readers with the skills needed to work successfully as developers and users of modeling and simulation. Featuring contributions written by leading experts in the field, the book's fluid presentation builds from topic to topic and provides the foundation and theoretical underpinnings of modeling and simulation. First, an introduction to the topic is presented, including related terminology, examples of model development, and various domains of modeling and simulation. Subsequent chapters develop the necessary mathematical background needed to understand modeling and simulation topics, model types, and the importance of visualization. In addition, Monte Carlo simulation, continuous simulation, and discrete event simulation are thoroughly discussed, all of which are significant to a complete understanding of modeling and simulation. The book also features chapters that outline sophisticated methodologies, verification and validation, and the importance of interoperability. A related FTP site features color representations of the book's numerous figures. Modeling and Simulation Fundamentals encompasses a comprehensive study of the discipline and is an excellent book for modeling and simulation courses at the upper-undergraduate and graduate levels. It is also a valuable reference for researchers and practitioners in the fields of computational statistics, engineering, and computer science who use statistical modeling techniques.