Modeling Biology
DOWNLOAD
Download Modeling Biology PDF/ePub or read online books in Mobi eBooks. Click Download or Read Online button to get Modeling Biology book now. This website allows unlimited access to, at the time of writing, more than 1.5 million titles, including hundreds of thousands of titles in various foreign languages. If the content not found or just blank you must refresh this page
Modeling Biology
DOWNLOAD
Author : Manfred Dietrich Laubichler
language : en
Publisher: MIT Press
Release Date : 2007
Modeling Biology written by Manfred Dietrich Laubichler and has been published by MIT Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with Biology categories.
Experts examine new modeling strategies for the interpretation of biological data and their integration into the conceptual framework of theoretical biology, detailing approaches that focus on morphology, development, behavior, or evolution. Abstract and conceptual models have become an indispensable tool for analyzing the flood of highly detailed empirical data generated in recent years by advanced techniques in the biosciences. Scientists are developing new modeling strategies for analyzing data, integrating results into the conceptual framework of theoretical biology, and formulating new hypotheses. In Modeling Biology, leading scholars investigate new modeling strategies in the domains of morphology, development, behavior, and evolution. The emphasis on models in the biological sciences has been accompanied by a new focus on conceptual issues and a more complex understanding of epistemological concepts. Contributors to Modeling Biology discuss models and modeling strategies from the perspectives of philosophy, history, and applied mathematics. Individual chapters discuss specific approaches to modeling in such domains as biological form, development, and behavior. Finally, the book addresses the modeling of these properties in the context of evolution, with a particular emphasis on the emerging field of evolutionary developmental biology (or evo-devo). Contributors Giorgio A. Ascoli, Chandrajit Bajaj, James P. Collins, Luciano da Fontoura Costa, Kerstin Dautenhahn, Nigel R. Franks, Scott Gilbert, Marta Ibañes Miguez, Juan Carlos Izpisúa-Belmonte, Alexander S. Klyubin, Thomas J. Koehnle, Manfred D. Laubichler, Sabina Leonelli, James A. R. Marshall, George R. McGhee Jr., Gerd B. Müller, Chrystopher L. Nehaniv, Karl J. Niklas, Lars Olsson, Eirikur Palsson, Daniel Polani, Diego Rasskin Gutman, Hans-Jörg Rheinberger, Alexei V. Samsonovich, Jeffrey C. Schank, Harry B. M. Uylings, Jaap van Pelt, Iain Werry
Biological Modeling And Simulation
DOWNLOAD
Author : Russell Schwartz
language : en
Publisher: MIT Press
Release Date : 2008-07-25
Biological Modeling And Simulation written by Russell Schwartz and has been published by MIT Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-07-25 with Science categories.
A practice-oriented survey of techniques for computational modeling and simulation suitable for a broad range of biological problems. There are many excellent computational biology resources now available for learning about methods that have been developed to address specific biological systems, but comparatively little attention has been paid to training aspiring computational biologists to handle new and unanticipated problems. This text is intended to fill that gap by teaching students how to reason about developing formal mathematical models of biological systems that are amenable to computational analysis. It collects in one place a selection of broadly useful models, algorithms, and theoretical analysis tools normally found scattered among many other disciplines. It thereby gives the aspiring student a bag of tricks that will serve him or her well in modeling problems drawn from numerous subfields of biology. These techniques are taught from the perspective of what the practitioner needs to know to use them effectively, supplemented with references for further reading on more advanced use of each method covered. The text, which grew out of a class taught at Carnegie Mellon University, covers models for optimization, simulation and sampling, and parameter tuning. These topics provide a general framework for learning how to formulate mathematical models of biological systems, what techniques are available to work with these models, and how to fit the models to particular systems. Their application is illustrated by many examples drawn from a variety of biological disciplines and several extended case studies that show how the methods described have been applied to real problems in biology.
Modeling In Systems Biology
DOWNLOAD
Author : Ina Koch
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-10-21
Modeling In Systems Biology written by Ina Koch and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-10-21 with Computers categories.
The emerging, multi-disciplinary field of systems biology is devoted to the study of the relationships between various parts of a biological system, and computer modeling plays a vital role in the drive to understand the processes of life from an holistic viewpoint. Advancements in experimental technologies in biology and medicine have generated an enormous amount of biological data on the dependencies and interactions of many different molecular cell processes, fueling the development of numerous computational methods for exploring this data. The mathematical formalism of Petri net theory is able to encompass many of these techniques. This essential text/reference presents a comprehensive overview of cutting-edge research in applications of Petri nets in systems biology, with contributions from an international selection of experts. Those unfamiliar with the field are also provided with a general introduction to systems biology, the foundations of biochemistry, and the basics of Petri net theory. Further chapters address Petri net modeling techniques for building and analyzing biological models, as well as network prediction approaches, before reviewing the applications to networks of different biological classification. Topics and features: investigates the modular, qualitative modeling of regulatory networks using Petri nets, and examines an Hybrid Functional Petri net simulation case study; contains a glossary of the concepts and notation used in the book, in addition to exercises at the end of each chapter; covers the topological analysis of metabolic and regulatory networks, the analysis of models of signaling networks, and the prediction of network structure; provides a biological case study on the conversion of logical networks into Petri nets; discusses discrete modeling, stochastic modeling, fuzzy modeling, dynamic pathway modeling, genetic regulatory network modeling, and quantitative analysis techniques; includes a Foreword by Professor Jens Reich, Professor of Bioinformatics at Humboldt University and Max Delbrück Center for Molecular Medicine in Berlin. This unique guide to the modeling of biochemical systems using Petri net concepts will be of real utility to researchers and students of computational biology, systems biology, bioinformatics, computer science, and biochemistry.
A Primer In Mathematical Models In Biology
DOWNLOAD
Author : Lee A. Segel
language : en
Publisher: SIAM
Release Date : 2013-05-09
A Primer In Mathematical Models In Biology written by Lee A. Segel and has been published by SIAM this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-05-09 with Science categories.
A textbook on mathematical modelling techniques with powerful applications to biology, combining theoretical exposition with exercises and examples.
Biomathematics
DOWNLOAD
Author : J. C. Misra
language : en
Publisher: World Scientific
Release Date : 2006
Biomathematics written by J. C. Misra and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006 with Science categories.
This book on modelling and simulation in biomathematics will be invaluable to researchers who are interested in the emerging areas of the field. Graduate students in related areas as well as lecturers will also find it beneficial. Some of the chapters have been written by distinguished experts in the field. Sample Chapter(s). Chapter 1: Detecting Mosaic Structures in DNA Sequence Alignments (1,349 KB). Contents: Detecting Mosaic Structures in DNA Sequence Alignments (D Husmeier); Application of Statistical Methodology and Model Design to Socio-Behaviour of HIV Transmission (J Oluwoye); A Stochastic Model Incorporating HIV Treatments for a Heterosexual Population: Impact on Threshold Conditions (R J Gallop et al.); Modeling and Identification of the Dynamics of the MF-Influenced Free-Radical Transformations in Lipid-Modeling Substances and Lipids (J Bentsman et al.); Computer Simulation of Self-Reorganization in Biological Cells (D Greenspan); Modelling Biological Gel Contraction by Cells: Consequences of Cell Traction Forces Distribution and Initial Stress (S Ramtani); Peristaltic Transport of Physiological Fluids (J C Misra & S K Pandey); Mathematical Modelling of DNA Knots and Links (J C Misra & S Mukherjee); Using Monodomain Computer Models for the Simulation of Electric Fields During Excitation Spread in Cardiac Tissue (G Plank); Flow in Tubes with Complicated Geometries with Special Application to Blood Flow in Large Arteries (G Jayaraman); Mathematical Modeling in Reproductive Biomedicine (S Sharma & S K Guha); Image Theory and Applications in Bioelectromagnetics (P D Einziger et al.); Dynamics of Humanoid Robots: Geometrical and Topological Duality (V G Ivancevic); The Effects of Body Composition on Energy Expenditure and Weight Dynamics During Hypophagia: A Setpoint Analysis (F P Kozusko); Mathematical Models in Population Dynamics and Ecology (R Diluo); Modelling in Bone Biomechanics (J C Misra & S Samanta). Readership: Graduate students, academic and researchers in biomathematics, mathematical biology, mathematical modeling, biotechnology, biocomputing, biophysics, bioengineering and mechanics."
Systems Biology
DOWNLOAD
Author : Andreas Kremling
language : en
Publisher: CRC Press
Release Date : 2013-11-12
Systems Biology written by Andreas Kremling and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-12 with Mathematics categories.
Drawing on the latest research in the field, Systems Biology: Mathematical Modeling and Model Analysis presents many methods for modeling and analyzing biological systems, in particular cellular systems. It shows how to use predictive mathematical models to acquire and analyze knowledge about cellular systems. It also explores how the models are sy
Dynamic Systems Biology Modeling And Simulation
DOWNLOAD
Author : Joseph DiStefano III
language : en
Publisher: Academic Press
Release Date : 2015-01-10
Dynamic Systems Biology Modeling And Simulation written by Joseph DiStefano III and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-01-10 with Science categories.
Dynamic Systems Biology Modeling and Simuation consolidates and unifies classical and contemporary multiscale methodologies for mathematical modeling and computer simulation of dynamic biological systems – from molecular/cellular, organ-system, on up to population levels. The book pedagogy is developed as a well-annotated, systematic tutorial – with clearly spelled-out and unified nomenclature – derived from the author’s own modeling efforts, publications and teaching over half a century. Ambiguities in some concepts and tools are clarified and others are rendered more accessible and practical. The latter include novel qualitative theory and methodologies for recognizing dynamical signatures in data using structural (multicompartmental and network) models and graph theory; and analyzing structural and measurement (data) models for quantification feasibility. The level is basic-to-intermediate, with much emphasis on biomodeling from real biodata, for use in real applications. Introductory coverage of core mathematical concepts such as linear and nonlinear differential and difference equations, Laplace transforms, linear algebra, probability, statistics and stochastics topics; PLUS ....... The pertinent biology, biochemistry, biophysics or pharmacology for modeling are provided, to support understanding the amalgam of “math modeling” with life sciences. Strong emphasis on quantifying as well as building and analyzing biomodels: includes methodology and computational tools for parameter identifiability and sensitivity analysis; parameter estimation from real data; model distinguishability and simplification; and practical bioexperiment design and optimization. Companion website provides solutions and program code for examples and exercises using Matlab, Simulink, VisSim, SimBiology, SAAMII, AMIGO, Copasi and SBML-coded models. A full set of PowerPoint slides are available from the author for teaching from his textbook. He uses them to teach a 10 week quarter upper division course at UCLA, which meets twice a week, so there are 20 lectures. They can easily be augmented or stretched for a 15 week semester course. Importantly, the slides are editable, so they can be readily adapted to a lecturer’s personal style and course content needs. The lectures are based on excerpts from 12 of the first 13 chapters of DSBMS. They are designed to highlight the key course material, as a study guide and structure for students following the full text content. The complete PowerPoint slide package (~25 MB) can be obtained by instructors (or prospective instructors) by emailing the author directly, at: [email protected]
Mathematical Modeling In Systems Biology
DOWNLOAD
Author : Brian P. Ingalls
language : en
Publisher: MIT Press
Release Date : 2022-06-07
Mathematical Modeling In Systems Biology written by Brian P. Ingalls and has been published by MIT Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-06-07 with Science categories.
An introduction to the mathematical concepts and techniques needed for the construction and analysis of models in molecular systems biology. Systems techniques are integral to current research in molecular cell biology, and system-level investigations are often accompanied by mathematical models. These models serve as working hypotheses: they help us to understand and predict the behavior of complex systems. This book offers an introduction to mathematical concepts and techniques needed for the construction and interpretation of models in molecular systems biology. It is accessible to upper-level undergraduate or graduate students in life science or engineering who have some familiarity with calculus, and will be a useful reference for researchers at all levels. The first four chapters cover the basics of mathematical modeling in molecular systems biology. The last four chapters address specific biological domains, treating modeling of metabolic networks, of signal transduction pathways, of gene regulatory networks, and of electrophysiology and neuronal action potentials. Chapters 3–8 end with optional sections that address more specialized modeling topics. Exercises, solvable with pen-and-paper calculations, appear throughout the text to encourage interaction with the mathematical techniques. More involved end-of-chapter problem sets require computational software. Appendixes provide a review of basic concepts of molecular biology, additional mathematical background material, and tutorials for two computational software packages (XPPAUT and MATLAB) that can be used for model simulation and analysis.
Mathematical Models In Biology
DOWNLOAD
Author : Leah Edelstein-Keshet
language : en
Publisher: SIAM
Release Date : 1987-12-01
Mathematical Models In Biology written by Leah Edelstein-Keshet and has been published by SIAM this book supported file pdf, txt, epub, kindle and other format this book has been release on 1987-12-01 with Mathematics categories.
This book is an introduction for readers interested in biological applications of mathematics and modeling in biology, showing how relatively simple mathematics can be applied to a variety of models. Despite the great advances that have taken place, the simple lessons described in the text are still important and informative.
Mathematical Modeling Of Biological Systems
DOWNLOAD
Author : Harvey J. Gold
language : en
Publisher: John Wiley & Sons
Release Date : 1977
Mathematical Modeling Of Biological Systems written by Harvey J. Gold and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 1977 with Science categories.
The modeling process - an overview. Dimension and similarity. Probability models. Dynamic processes. Interacting dynamic processes. Feedback control and stability of biological systems. Curve fiting: estimating the parameters. Computing.