Molecular Biology Hematopoiesis And Treatment Of Leukemia And Cancer
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Molecular Biology Hematopoiesis And Treatment Of Leukemia And Cancer
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Author : Nader G. Abraham
language : en
Publisher: S Karger Ag
Release Date : 2001-01-01
Molecular Biology Hematopoiesis And Treatment Of Leukemia And Cancer written by Nader G. Abraham and has been published by S Karger Ag this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-01-01 with Medical categories.
Molecular Biology Of Hematopoiesis 5
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Author : Nader G. Abraham
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Molecular Biology Of Hematopoiesis 5 written by Nader G. Abraham and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
This volume of Molecular Biology of Hematopoiesis is dedicated to John W. Adam son, M. D. , Tadamitsu Kishimoto, M. D. , Robert C. Gallo, M. D. , Arthur W. Nienhuis, M. D. , and Franco Mandelli, M. D. , for their contributions in developing an overall view of the state-of-the-art knowledge in the field of hematopoiesis. Richard Champlin, among other renowned clinicians, presented updated information on stem cells and T-cell depletion for bone marrow transplant. A clinical update on thrombopoietin was presented by Pamela Hunt of Amgen and by Kenneth Kaushansky. Arthur Nienhuis' and Katherine Turner's contribu tions to our current knowledge and advances in the fields of growth factors and gene transfer were also recognized during the 9th Symposium on Molecular Biology of Hematopoiesis in Genoa. The chapters cover such diverse areas as preclinical and clinical updates on growth factors and positive and negative regulatory molecules. "Advances in Leukemia: Mechanism and Treatment by Interferon" was presented by Professor Sante Tura. Readers will find presentation of exciting advances that have occurred in the area of hematopoiesis. The elucidation of gene structures of key growth factor proteins such as IL-12 and IL-II will lead to new insights and new approaches in understanding the regulation of hematopoiesis, as well as application of new growth factors.
Proceedings Of The 13th Symposium On Molecular Biology Of Hematopoiesis And Treatment Of Leukemia And Cancer
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Author : Nader G Abraham
language : en
Publisher:
Release Date : 2001
Proceedings Of The 13th Symposium On Molecular Biology Of Hematopoiesis And Treatment Of Leukemia And Cancer written by Nader G Abraham and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001 with categories.
Molecular Biology Of Hematopoiesis And Treatment Of Leukemia And Cancer
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Author : N. G. Abraham
language : en
Publisher: S. Karger AG (Switzerland)
Release Date : 2000-01-01
Molecular Biology Of Hematopoiesis And Treatment Of Leukemia And Cancer written by N. G. Abraham and has been published by S. Karger AG (Switzerland) this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-01-01 with Medical categories.
Molecular Biology Of Hematopoiesis 6
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Author : Nader G. Abraham
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Molecular Biology Of Hematopoiesis 6 written by Nader G. Abraham and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
This volume of Molecular Biology of Hematopoiesis is dedicated to many inter national scientists and clinicians for their contribution to the field of Hematology/ Oncology presented at the 11th International Symposium on Molecular Biology of Hematopoiesis, which was held in Bormio, Italy, June 25-29, 1998. The continuous support of the Presidents of the meeting, Professor F. Takaku, President of Jichi University, and E. D. Thomas, Nobel Laureate, was greatly acknowledged, especially Professor Takaku, for his vision and support for development of gene therapy in Japan. New information on BMT for autoimmune disease and organ transplantation was presented at the symposium and is published in this volume. Several new findings on gene therapy/transfer into HSC were presented by E. F. Vanin and A. Nienhuis, K. Humphries, 1. A. Nolta, H. E. Heslop, and M. K. Brenner. Professors S. Asano and K. Tani presented new studies on gene transfer into primates. Among the highlights were the new papers on gene transfer presented by G. Wage maker, N. G. Abraham, and M. Onoderea from R. M. BJaese's group. The use of BMT for organ transplant and autoim mune disease was updated and a representative paper is presented in this volume.
13th Symposium On Molecular Biology Of Hematopoiesis And Treatment Of Leukemia And Cancer
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Author :
language : en
Publisher:
Release Date : 2000
13th Symposium On Molecular Biology Of Hematopoiesis And Treatment Of Leukemia And Cancer written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000 with categories.
Hematopoietic Growth Factors In Oncology
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Author : Gary Lyman
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-11-05
Hematopoietic Growth Factors In Oncology written by Gary Lyman and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-11-05 with Medical categories.
Progress in the treatment of cancer over the past two decades has been rapid with many new and novel therapeutic modalities arriving at an unprecedented pace. Overall cancer mortality rates have actually begun to fall in parallel with progress in the diagnosis and treatment of malignant disease. Despite our advances in the understanding of the biology and molecular genetics of cancer, as well as the availability of an increasing array of effective therapies, cancer treatment today and for the foreseeable future will include the traditional modalities of surgery, radiation therapy and chemotherapy. Myelosuppressive agents with their potential hematopoietic toxicities remain the mainstay of systemic treatment for both metastatic and early stage cancer. The complications of cancer chemotherapy have serious impact on a patient’s well being and overall quality of life. Fortunately, advances in cancer treatment have been accompanied by equally impressive progress in the availability of a wide array of supportive care modalities which have greatly enhanced the ability of oncologists to minimize the impact of cancer and its treatment on patient quality of life as well improve delivery of potentially curative cancer treatment. Despite the increasing complexity of modern cancer treatment, it is the obligation of the oncologist as well as the entire cancer care team to be certain that cancer patients receive the optimal supportive care available for their disease and its treatment. Among the most serious and potentially life threatening toxicities of cancer treatment are the hematologic toxicities accompanying myelosuppression including anemia and associated asthenia and fatigue, neutropenia and fever associated with infection in the immunocompromised patient and thrombocytopenia and accompanying risk of bleeding. Special supportive care needs arise in the very elderly care patient that may tax the ability of even the most skilled clinician. Despite the considerable progress that has been made with more effective and safer treatment strategies, myelosuppressive chemotherapy will remain the mainstay of systemic treatment for cancer for the foreseeable future. While considerable progress has occurred, better methods and broader application of supportive care measures are needed to reduce the symptomatic effects of cancer and the associated toxicities associated with cancer treatment. No area of cancer supportive care better illustrates the progress that has resulted from advances in our understanding of cellular and molecular biology, genetic engineering and the development of more effective yet often more toxic cancer treatments than that of the hematopoietic growth factors. This volume will review and integrate the major advances in our understanding of the underlying molecular biology and pharmacology of these agents along with the results of well designed and executed randomized controlled trials of the erythroid stimulating agents, the myeloid growth factors and the new thrombopoietic agents each addressing a major threat associated with bone marrow suppression accompanying cancer treatment. The current clinical utilization of these agents is based on numerous randomized controlled trials and meta-analyses along with evidence-based clinical practice guidelines developed by professional societies guiding their appropriate and cost-effective use in clinical care.
Hematologic Cancers From Molecular Pathobiology To Targeted Therapeutics
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Author : Jianguo Tao
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-11-13
Hematologic Cancers From Molecular Pathobiology To Targeted Therapeutics written by Jianguo Tao and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-11-13 with Medical categories.
In the last decade, there has been a remarkable explosion of knowledge in hematologic cancer from basic molecular biology and pathology to clinical therapy. This has led to many new advance and insights in the understanding of pathobiology of malignant hematology. New knowledge of disease molecular pathology, cytogenetic, epigenetic and genomic alterations have provided new strategies to attack and eradicate tumor cells at molecular level and significantly impacted our current therapeutics for hematological malignancies. The recent and ongoing rapid expansion of knowledge in this area has become extensive, dynamic and diffuse over the literature and research publications. This has led to the need to capture and compile the new and current information about hematologic cancer with special emphasis on translation from molecular pathobiology to targeted therapeutics. In this book experts from around the world share their thoughts and knowledge about the pathobiology of hematologic cancer, as well as their view on current treatment approaches and future development in these malignant hematologic diseases. This book is well suited for hematology residents, fellows and hematology-oncology physicians, hematopathologist as well as basic research scientist in the area of hematologic malignancies.
Molecular Basis Of Hematopoiesis
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Author : Amittha Wickrema
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-12-26
Molecular Basis Of Hematopoiesis written by Amittha Wickrema and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-12-26 with Medical categories.
Although much is known with respect to blood cell formation and function, many new concepts in the areas of the regulation of hematopoietic stem cell commitment and the subsequent survival, proliferation, and differentiation of progenitors have been elucidated in the last five years. Our understanding of the microenvironment where stem cells reside and commit to distinct blood types (the niche) has grown significantly in recent years. Furthermore, blood cells have been used as the key model system to study microRNA function and the role of microRNAs in the transformation of normal cells into cancer cells. The current volume Molecular Basis of Hematopoiesis, edited by Amittha Wickrema & Barbara Kee, provides the most recent developments in the area in addition to a chapter on the utilization of basic science knowledge for the treatment of blood diseases. Each chapter in this book has been written and edited by faculty in major academic and research institutions around the world, who are pushing the frontiers of research in this important area.
Biology And Treatment Of Leukemia And Bone Marrow Neoplasms
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Author : Vinod Pullarkat
language : en
Publisher: Springer Nature
Release Date : 2021-10-09
Biology And Treatment Of Leukemia And Bone Marrow Neoplasms written by Vinod Pullarkat and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-10-09 with Medical categories.
This book provides a concise update on current understanding of the biology of acute and chronic leukemias and other bone marrow neoplasms, including myelodysplastic and myeloproliferative disorders, and explores new and emerging treatments. There is a particular focus on the molecular abnormalities that are drivers of leukemia and on their detection by modern molecular techniques. Knowledge of the ways in which genomic and metabolic abnormalities in the hematologic neoplasms affect prognosis and treatment decision making is reviewed. Detailed attention is devoted to targeted therapies, including novel drugs, and to potential targets for future drug development. In addition, readers find in-depth discussion of cellular and antibody-based immunotherapies as well as the role of hematopoietic stem cell transplantation in the treatment of leukemias and bone marrow malignancies. The book is of special interest for hematologists, oncologists, and cancer researchers; it is also of value for hematology trainees and medical students.