Molecular Glycobiology
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Molecular Glycobiology
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Author : Minoru Fukuda
language : en
Publisher:
Release Date : 1994
Molecular Glycobiology written by Minoru Fukuda and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994 with Science categories.
Cell-surface carbohydrates play critical roles in cell-cell interactions. This well-written book brings together leading researchers to detail major recent advances regarding our understanding of the molecular mechanisms underlying such processes. Emphasis is given to cell type, specific carbohydrate expression, and the carbohydrates and proteins involved in cell recognition. Topics include the molecular structure of animal lectins, carbohydrate recognition in cell-cell interaction, chemical synthesis of oligosaccharides, conformational studies on oligosaccharides, and cell-surface carbohydrates, among others. Also included is a full discussion of key experimental approaches such as chemical synthesis and the three-dimensional structural analysis of carbohydrates. Providing both an up-to-date description of the subject and a forecast of likely future developments, Molecular Glycobiology is a much-needed synopsis of an exciting and rapidly expanding field. It will be welcomed by students and researchers in molecular biology, biochemistry, cell biology, and glycobiology.
Functional And Molecular Glycobiology
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Author : Dr Susan Brooks
language : en
Publisher: Taylor & Francis
Release Date : 2023-06-14
Functional And Molecular Glycobiology written by Dr Susan Brooks and has been published by Taylor & Francis this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-06-14 with Science categories.
Functional and Molecular Glycobiology explains the chemistry of carbohydrates, and the biosynthesis and diversity of different types of glycans. It looks at the functional role of glycoconjugate compounds in normal cellular processes, in both disease and development. The book also describes how these compounds can be studied, analysed and manipulated for use in biotechnology. Functional and Molecular Glycobiology is a unique introduction to the field bridging the gap between introductory books and current research.
Functional And Molecular Glycobiology
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Author : Susan A. Brooks
language : en
Publisher: Garland Pub
Release Date : 2002
Functional And Molecular Glycobiology written by Susan A. Brooks and has been published by Garland Pub this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Science categories.
Functional and Molecular Glycobiology explains the chemistry of carbohydrates, and the biosynthesis and diversity of different types of glycans. It looks at the functional role of glycoconjugate compounds in normal cellular processes, in both disease and development. The book also describes how these compounds can be studied, analysed and manipulated for use in biotechnology. Functional and Molecular Glycobiology is a unique introduction to the field bridging the gap between introductory books and current research.
Structural Glycobiology
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Author : Elizabeth Yuriev
language : en
Publisher: CRC Press
Release Date : 2012-09-27
Structural Glycobiology written by Elizabeth Yuriev and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-09-27 with Medical categories.
Structural Glycobiology covers the experimental, theoretical, and alternative technologies used in the study of the structural basis for the diverse biological roles of carbohydrates. The book overviews the application of specialized technologies to the study of carbohydrates in biology, reviews relevant and current research in the field, and is illustrated throughout by specific examples of how research investigations have yielded key structural and associated biological data on carbohydrates and glycolipids. In particular, the book focuses on: X-ray crystallography and small-angle scattering, NMR, and cryo-electron microscopy techniques Theoretical (modeling-based) approaches, such as molecular mechanics, molecular dynamics, free energy calculations, and carbohydrate docking Alternative techniques for yielding structural information on carbohydrates from complex biological samples Carbohydrates in medicine, specifically in areas that have been directly impacted by our understanding of the structural role of carbohydrates in immune recognition: cancer, organ transplantation, and infection
Functional And Molecular Glycobiology
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Author : Susan A. Brooks
language : en
Publisher:
Release Date : 2021
Functional And Molecular Glycobiology written by Susan A. Brooks and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021 with SCIENCE categories.
Functional and Molecular Glycobiology explains the chemistry of carbohydrates, and the biosynthesis and diversity of different types of glycans. It looks at the functional role of glycoconjugate compounds in normal cellular processes, in both disease and development. The book also describes how these compounds can be studied, analysed and manipulated for use in biotechnology. Functional and Molecular Glycobiology is a unique introduction to the field bridging the gap between introductory books and current research.
Molecular And Cellular Glycobiology
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Author : Minoru Fukuda
language : en
Publisher: Oxford University Press on Demand
Release Date : 2000
Molecular And Cellular Glycobiology written by Minoru Fukuda and has been published by Oxford University Press on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000 with Science categories.
Molecular and Cellular Glycobiology covers the recent progress in understanding the biological roles of carbohydrates and includes basic knowledge of carbohydrates in mammals. Emphasis is on structure, biosynthesis and function of carbohydrates in development and disease. In particular,biological significance in immune cells, neural cells and cytoplasmic and nuclear proteins are thoroughly described. In addition, Molecular and Cellular Glycobiology updates the knowledge of diseases caused by anomalies of carbohydrate biosynthesis and the animal models used to investigate thephysiological roles of carbohydrates including carbohydrates attached to lipids. Various attempts to develop therapeutic agents based on carbohydrates are also described. Molecular and Cellular Glycobiology covers recent developments in a comprehensive yet focused manner and will be of interest toanyone with a basic knowledge of carbohydrates.
Essentials Of Glycobiology
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Author : Ajit Varki
language : en
Publisher: CSHL Press
Release Date : 1999
Essentials Of Glycobiology written by Ajit Varki and has been published by CSHL Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999 with Medical categories.
Sugar chains (glycans) are often attached to proteins and lipids and have multiple roles in the organization and function of all organisms. "Essentials of Glycobiology" describes their biogenesis and function and offers a useful gateway to the understanding of glycans.
Bioinformatics For Glycobiology And Glycomics
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Author : Claus-Wilhelm von der Lieth
language : en
Publisher: John Wiley & Sons
Release Date : 2009-10-01
Bioinformatics For Glycobiology And Glycomics written by Claus-Wilhelm von der Lieth and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-10-01 with Medical categories.
This book is the first to be dedicated to the bioinformatics of carbohydrates and glycoproteins. It provides an introduction to this emerging field of science both for the experimentalist working in glycobiology and glycomics, and also for the computer scientist looking for background information for the development of highly sophisticated algorithmic approaches. The book provides an overview of the state-of-the-art in the field, with reviews on databases, and the tools in use for analysis, interpretation, and prediction of the structures of complex carbohydrates, and demonstrates the value of bioinformatics for glycobiology. The availability of comprehensive databases and corresponding bioinformatics tools, to access and analyse the large amounts of experimental data relating to the structure of carbohydrates, will be a prerequisite for the success of the large-scale glycomics projects that aim to decipher new, so far unknown, biological functions of glycans. Efficient bioinformatics descriptions and tools can considerably enhance the efficiency of glycomics research, in terms of data quality, analysis and experimental costs. For a complete understanding of the molecular processes in which carbohydrates are involved, such as protein–carbohydrate interactions and the impact of glycosylation on protein function, knowledge of the 3D structure of the carbohydrate, the protein–carbohydrate complex, or the glycoprotein is often indispensable. This book provides a thorough introduction into methods used for conformational analysis of carbohydrates. Key features: Describes bioinformatic approaches to handle carbohydrate-active enzymes and glycosylation. Provides an overview on bioinformatics tools that facilitate analysis of carbohydrate structures. Gives introduction into molecular modelling of carbohydrate 3D structure and carbohydrates contained in the Protein Databank. Assumes only a basic knowledge of biology and bioinformatics.
Sialo Xenoantigenic Glycobiology
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Author : Kwon-Ho Song
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-11-02
Sialo Xenoantigenic Glycobiology written by Kwon-Ho Song and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-11-02 with Technology & Engineering categories.
Carbohydrate antigens on glycoconjugates of mammalian cells play crucial roles in various biological processes and are epitopes recognized by the immune system, as glycobiology has hugely been progressed during the past two decades. The book focuses on sialic acid–based xenoantigenes. In pig to human xenotransplantation, exposure of pig organs to human blood results in hyper acute rejection (HAR), caused by differences in carbohydrate epitopes between human and pig vascular endothelia. Although Gal-antigen as major antigen was eliminated, the remaining non-Gal antigens are considered to be xenoantigens. Sialosyl-Tn or Hanganutziu-Deicher (HD), are non-Gal antigens specific to natural antibodies in human. To overcome rejection responses such as HAR, studies of genes involved in carbohydrate antigens, causing xenoantigenicity, are necessary. Knowledge of pig glycosyltransferases are also useful to apply to xenoantigen masking or identification of the xenoantigenic sialylglycan(s). In the first chapter the screening for pig glycosyltransferase genes for xenoantigens is presented. In the chapter II to IV the cloning, characterization, and investigation of the regulatory mechanism of the pig CMAH gene in NeuGc biosynthesis is shown. Lastly, the effects of an alteration of pig glycosylation patterns on human serum-mediated cytotoxicity, caused by human sialyltransferases including hST6GalNAc IV is presented.
Introduction To Glycobiology
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Author : Maureen E. Taylor
language : en
Publisher: Oxford University Press, USA
Release Date : 2011-04-21
Introduction To Glycobiology written by Maureen E. Taylor and has been published by Oxford University Press, USA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-04-21 with Medical categories.
Introduction to Glycobiology reveals the true impact of the sugars on biological systems, explaining their function at the molecular, cellular, and organismal level and their clinical relevance.