Mr Dark Side N Mero Dos
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Translational Medicine
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Author : Joy A. Cavagnaro
language : en
Publisher: CRC Press
Release Date : 2021-11-26
Translational Medicine written by Joy A. Cavagnaro and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-26 with Medical categories.
Translational Medicine: Optimizing Preclinical Safety Evaluation of Biopharmaceuticals provides scientists responsible for the translation of novel biopharmaceuticals into clinical trials with a better understanding of how to navigate the obstacles that keep innovative medical research discoveries from becoming new therapies or even making it to clinical trials. The book includes sections on protein-based therapeutics, modified proteins, oligonucleotide-based therapies, monoclonal antibodies, antibody–drug conjugates, gene and cell-based therapies, gene-modified cell-based therapies, combination products, and therapeutic vaccines. Best practices are defined for efficient discovery research to facilitate a science-based, efficient, and predictive preclinical development program to ensure clinical efficacy and safety. Key Features: Defines best practices for leveraging of discovery research to facilitate a development program Includes general principles, animal models, biomarkers, preclinical toxicology testing paradigms, and practical applications Discusses rare diseases Discusses "What-Why-When-How" highlighting different considerations based upon product attributes. Includes special considerations for rare diseases About the Editors Joy A. Cavagnaro is an internationally recognized expert in preclinical development and regulatory strategy with an emphasis on genetic medicines.. Her 40-year career spans academia, government (FDA), and the CRO and biotech industries. She was awarded the 2019 Arnold J Lehman Award from the Society of Toxicology for introducing the concept of science-based, case-by-case approach to preclinical safety evaluation, which became the foundation of ICH S6. She currently serves on scientific advisory boards for advocacy groups and companies and consults and lectures in the area of preclinical development of novel therapies. Mary Ellen Cosenza is a regulatory toxicology consultant with over 30 years of senior leadership experience in the biopharmaceutical industry in the U.S., Europe, and emerging markets. She has held leadership position in both the American College of Toxicology (ACT) and the International Union of Toxicology (IUTOX) and is also an adjunct assistant professor at the University of Southern California where she teaches graduate-level courses in toxicology and regulation of biologics.
Gotta Get Theroux This
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Author : Louis Theroux
language : en
Publisher: Pan Macmillan
Release Date : 2019-09-19
Gotta Get Theroux This written by Louis Theroux and has been published by Pan Macmillan this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-09-19 with Biography & Autobiography categories.
From much-loved documentary maker Louis Theroux comes a funny, heartfelt and entertaining account of his life and weird times in TV. The Sunday Times Bestseller. 'Honest and soul-searching' - Sunday Express ______________ In 1994 fledgling journalist Louis Theroux was given a one-off gig on Michael Moore’s TV Nation, presenting a segment on apocalyptic religious sects. Gawky, socially awkward and totally unqualified, his first reaction to this exciting opportunity was panic. But he’d always been drawn to off-beat characters, so maybe his enthusiasm would carry the day. Or, you know, maybe it wouldn’t . . . In Gotta Get Theroux This, Louis takes the reader on a joyous journey from his anxiety-prone childhood to his unexpectedly successful career. Nervously accepting the BBC’s offer of his own series, he went on to create an award-winning documentary style that has seen him immersed in the weird worlds of paranoid US militias and secretive pro-wrestlers, get under the skin of celebrities like Max Clifford and Chris Eubank and tackle gang culture in San Quentin prison, all the time wondering whether the same qualities that make him good at documentaries might also make him bad at life. As Louis woos his beautiful wife Nancy and learns how to be a father, he also dares to take on the powerful Church of Scientology. Just as challenging is the revelation that one of his old subjects, Jimmy Savile, was a secret sexual predator, prompting him to question our understanding of how evil takes place. Filled with wry observation and self-deprecating humour, this is Louis at his most insightful and honest best. ______________ 'Funny, engaging' - Sunday Times 'Gripping' - Daily Mail 'Absorbing and surprisingly candid' - Telegraph Magazine
The Great Transformation
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Author : Karl Polanyi
language : en
Publisher: Penguin Classics
Release Date : 2024-06-20
The Great Transformation written by Karl Polanyi and has been published by Penguin Classics this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-06-20 with Business & Economics categories.
'One of the most powerful books in the social sciences ever written. ... A must-read' Thomas Piketty 'The twentieth century's most prophetic critic of capitalism' Prospect Karl Polanyi's landmark 1944 work is one of the earliest and most powerful critiques of unregulated markets. Tracing the history of capitalism from the great transformation of the industrial revolution onwards, he shows that there has been nothing 'natural' about the market state. Instead of reducing human relations and our environment to mere commodities, the economy must always be embedded in civil society. Describing the 'avalanche of social dislocation' of his time, Polanyi's hugely influential work is a passionate call to protect our common humanity. 'Polanyi's vision for an alternative economy re-embedded in politics and social relations offers a refreshing alternative' Guardian 'Polanyi exposes the myth of the free market' Joseph Stiglitz With a new introduction by Gareth Dale
Human Health And Performance Risks Of Space Exploration Missions
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Author : Jancy C. McPhee
language : en
Publisher: U. S. National Aeronautics & Space Administration
Release Date : 2009
Human Health And Performance Risks Of Space Exploration Missions written by Jancy C. McPhee and has been published by U. S. National Aeronautics & Space Administration this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009 with Biography & Autobiography categories.
Encyclopedia Of Infectious Diseases
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Author : Michel Tibayrenc
language : en
Publisher: John Wiley & Sons
Release Date : 2007-07-31
Encyclopedia Of Infectious Diseases written by Michel Tibayrenc and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-07-31 with Science categories.
Discover how the application of novel multidisciplinary, integrative approaches and technologies are dramatically changing our understanding of the pathogenesis of infectious diseases and their treatments. Each article presents the state of the science, with a strong emphasis on new and emerging medical applications. The Encyclopedia of Infectious Diseases is organized into five parts. The first part examines current threats such as AIDS, malaria, SARS, and influenza. The second part addresses the evolution of pathogens and the relationship between human genetic diversity and the spread of infectious diseases. The next two parts highlight the most promising uses of molecular identification, vector control, satellite detection, surveillance, modeling, and high-throughput technologies. The final part explores specialized topics of current concern, including bioterrorism, world market and infectious diseases, and antibiotics for public health. Each article is written by one or more leading experts in the field of infectious diseases. These experts place all the latest findings from various disciplines in context, helping readers understand what is currently known, what the next generation of breakthroughs is likely to be, and where more research is needed. Several features facilitate research and deepen readers' understanding of infectious diseases: Illustrations help readers understand the pathogenesis and diagnosis of infectious diseases Lists of Web resources serve as a gateway to important research centers, government agencies, and other sources of information from around the world Information boxes highlight basic principles and specialized terminology International contributions offer perspectives on how infectious diseases are viewed by different cultures A special chapter discusses the representation of infectious diseases in art With its multidisciplinary approach, this encyclopedia helps point researchers in new promising directions and helps health professionals better understand the nature and treatment of infectious diseases.
Paramount S International News
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Author :
language : en
Publisher:
Release Date : 1943
Paramount S International News written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1943 with House organs categories.
Living Fossils
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Author : N. Eldredge
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Living Fossils written by N. Eldredge and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
The case history approach has an impressive record of success in a variety of disciplines. Collections of case histories, casebooks, are now widely used in all sorts of specialties other than in their familiar appli cation to law and medicine. The case method had its formal beginning at Harvard in 1871 when Christopher Lagdell developed it as a means of teaching. It was so successful in teaching law that it was soon adopted in medical education, and the collection of cases provided the raw material for research on various diseases. Subsequently, the case history approach spread to such varied fields as business, psychology, management, and economics, and there are over 100 books in print that use this approach. The idea for a series of Casehooks in Earth Science grew from my experience in organizing and editing a collection of examples of one variety of sedimentary deposits. The prqject began as an effort to bring some order to a large number of descriptions of these deposits that were so varied in presentation and terminology that even specialists found them difficult to compare and analyze. Thus, from the beginning, it was evident that something more than a simple collection of papers was needed. Accordingly, the nearly fifty contributors worked together with George de Vries Klein and me to establish a standard format for presenting the case histories.
The Hero With A Thousand Faces
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Author : Joseph Campbell
language : en
Publisher: HarperCollins UK
Release Date : 1988
The Hero With A Thousand Faces written by Joseph Campbell and has been published by HarperCollins UK this book supported file pdf, txt, epub, kindle and other format this book has been release on 1988 with Folklore categories.
A study of heroism in the myths of the world - an exploration of all the elements common to the great stories that have helped people make sense of their lives from the earliest times. It takes in Greek Apollo, Maori and Jewish rites, the Buddha, Wotan, and the bothers Grimm's Frog-King.
Severe Community Acquired Pneumonia
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Author : Jordi Rello
language : en
Publisher: Springer Science & Business Media
Release Date : 2001-06-30
Severe Community Acquired Pneumonia written by Jordi Rello and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-06-30 with Medical categories.
Severe Community Acquired Pneumonia is a book in which chapters are authored and the same topics discussed by North American and European experts. This approach provides a unique opportunity to view the different perspectives and points of view on this subject. Severe CAP is a common clinical problem encountered in the ICU setting. This book reviews topics concerning the pathogenesis, diagnosis and management of SCAP. The discussions on the role of alcohol in severe CAP and adjunctive therapies are important topics that further our understanding of this severe respiratory infection.
A New Dictionary Of The Portuguese And English Languages
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Author : D. José De Lacerda
language : en
Publisher: BoD – Books on Demand
Release Date : 2023-02-22
A New Dictionary Of The Portuguese And English Languages written by D. José De Lacerda and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-02-22 with Fiction categories.
Reprint of the original, first published in 1871. The publishing house Anatiposi publishes historical books as reprints. Due to their age, these books may have missing pages or inferior quality. Our aim is to preserve these books and make them available to the public so that they do not get lost.