Myocardial Ischemia
DOWNLOAD
Download Myocardial Ischemia PDF/ePub or read online books in Mobi eBooks. Click Download or Read Online button to get Myocardial Ischemia book now. This website allows unlimited access to, at the time of writing, more than 1.5 million titles, including hundreds of thousands of titles in various foreign languages. If the content not found or just blank you must refresh this page
Myocardial Ischemia And Arrhythmia
DOWNLOAD
Author : M. Zehender
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Myocardial Ischemia And Arrhythmia written by M. Zehender and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
This volume presents, in synoptic form, the latest and most comprehensive experimental and multi-faceted clinical findings on the potential arrythmogenic implications of acute myocardial ischemia. Together with a critical discussion of the related diagnostic and therapeutic consequences and outcomes, it presents a solid basis for efforts to reduce the occurance of sudden cardiac death in patients with coronary heart disease.
Myocardial Ischemia Mechanisms Reperfusion Protection
DOWNLOAD
Author : Morris Karmazyn
language : en
Publisher: Birkhäuser
Release Date : 2013-03-12
Myocardial Ischemia Mechanisms Reperfusion Protection written by Morris Karmazyn and has been published by Birkhäuser this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-12 with Medical categories.
Myocardial ischemia and subsequent reperfusion of the ischemic myocardium represent complex phenomena encompassing numerous physiological processes. This book aims at enhancing our understanding of these processes and stresses recent important developments in this very active area of research. The concise, state-of-the-art reviews cover recent advances in many fields important to the area of myocardial ischemia and reperfusion including physiology, pathology, pharmacology, biochemistry and molecular biology with reference to clinical relevance and applicability of these findings. Major areas which are highlighted include vascular mechanisms resulting in myocardial ischemia, cellular events in the ischemic, postinfarcted and reperfused myocardium as well as new exciting developments in cardiac protection that involve both novel pharmacological approaches as well as endogenous cardioprotective mechanisms such as preconditioning. Aimed at both the basic and clinical cardiovascular investigator, the book comprehensively reviews the rapid progress made in recent years in understanding the etiology of myocardial ischemia and reperfusion. It will further serve as an authoritative reference for all those interested in learning about the important developments in the treatment of myocardial ischemic and reperfusion disorders.
Myocardial Ischemia
DOWNLOAD
Author : Dennis V. P. Cokkinos
language : en
Publisher: Springer Science & Business Media
Release Date : 2006-03-08
Myocardial Ischemia written by Dennis V. P. Cokkinos and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-03-08 with Medical categories.
Effective new treatments of heart disease are based on a refined understanding of cellular function and the heart's response to environmental stresses. Not surprisingly therefore, the field of experimental cardiology has experienced a phase of rapid expo nential growth during the last decade. The acquisition of new knowledge has been so fast that textbooks of cardiology or textbooks of cardiovascular physiology are often hard-pressed to keep up with the most important conceptual advances. Witness the explosive increase in knowledge about signaling pathways of cardiac growth, transcrip tional regulation of cardiac metabolism, hormonal signaling, and the complex responses of the heart to ischemia, reperfusion, or ischemic preconditioning. This book is meant to bridge the gap between original literature and textbook reviews. It brings together inves tigators of various backgrounds who share their expertise in the biology of myocardial ischemia. Each chapter is a self-contained mini-review, but it will soon become apparent to the reader that there is also a common thread: Molecular and cellular cardiology has never been more exciting than now, but ever more exciting times are yet to come. The Editors ACKNOWLEDGEMENTS - Publication of this book was generously supported by Sanofi-Aventis Hellas. - Eikon creative team provided the technical assistance in preparing the manuscripts. - We thank Dr. Bernard Swynghedauw for all his scientific support.
Pathophysiology And Rational Pharmacotherapy Of Myocardial Ischemia
DOWNLOAD
Author : G. Heusch
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-06-29
Pathophysiology And Rational Pharmacotherapy Of Myocardial Ischemia written by G. Heusch and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-29 with Medical categories.
Ischemie heart disease is still the most frequent cause of death in the western world. There have been significant achievements in diagnostic procedures as well as in the medical, invasive, and surgiealtreatment ofischemieheart disease inrecent years. A variety ofdrugs are availablefor the pharmacotherapyofischemieheart disease, par ticularly nitrates, ß-blockers, and calcium-antagonists which are used as mono therapy or in various combinations. However, the selection of patients for a certain treatment, as weIl as the optimization of an individual treatment are still largely empirical. On the other hand, the recent advances in experimental cardiology emphasize the extremely complex and dynamie scenario of ischemic heart disease, involving endothelial damage, coagulation processes, metabolie and morphologie derangements, coronary constrictor mechanisms, blood flow redistribution, arrhythmogenesis, contraetile dysfunction during ischemia and reperfusion, and finally lack or presence of pain perception. Therefore, it appears desirable to close the gap between experimental and clinical cardiology and, thus, to provide a pathophysiologieal basis for rational cliniealdecisions with respect to diagnostic and therapeutic procedures. The idea for this book arose during the preparation of a seminar series on experi mental cardiology, when I found it diffieultto collect the pertinentinformation from textbooks of cardiology, physiology, pathology, and pharmacology, as well as from numerous review and original artieies on specifictopies. I am now very grateful that expert cliniealand experimental colleagues from around the world have joined me in the effort to provide a comprehensive textbook on the pathophysiology of myocar dial ischemia and its rational pharmacotherapy.
Myocardial Ischemia And Preconditioning
DOWNLOAD
Author : Naranjan S. Dhalla
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Myocardial Ischemia And Preconditioning written by Naranjan S. Dhalla and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Current evidence suggests that the ischemic preconditioning response is a multi-factorial process consisting of an initial early trigger, an intermediate mediator, and an end effector. Each of these steps in is now its own intense area of investigation. The need to render the heart ischemic for a brief period to invoke the preconditioning response is currently the major factor limiting clinical application of this powerful cardioprotective strategy. Recent research efforts have utilized brief exposures to pharmacological agents, in lieu of a brief preconditioning ischemia, to trigger/mimic the ischemic preconditioning-induced response. The World Heart Congress held in Winnipeg in July 2001 provided a forum for the presentation of new insights into the basic mechanisms of ischemia and reperfusion injury, as well as novel strategies to protect the heart from cell death, ventricular arrhythmias, and contractile dysfunction. Many pioneers in the fields of ischemia-reperfusion injury and preconditioning-induced protection presented there and the chapters in this book represent selected papers from these symposia.
Myocardial Ischemia And Reperfusion
DOWNLOAD
Author : Michael V. Cohen
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Myocardial Ischemia And Reperfusion written by Michael V. Cohen and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
The articles collected in this volume largely arose from two related meetings held last spring. The first was held in Buenos Aires, Argentina on April 11-12, 1997 and was titled Nuevos Avances en el Fenómeno de Isquemia y Reperfusión (New Advances in the Phenomenon of Ischemia and Reperfusion). The second meeting took place in Stará Lesná located in the High Tatras Mountains of the Slovak Republic on June 27-30, 1997. Both meetings were sponsored by several organizations including the International Society and Federation of Cardiology, the International Society for Heart Research and The American Heart Association.
Silent Myocardial Ischemia
DOWNLOAD
Author : W. Rutishauser
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Silent Myocardial Ischemia written by W. Rutishauser and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
This book presents the papers given at the International Symposium on Silent Myocardial Ischemia held on 27 and 28 May 1983 in Geneva, Switzerland. The symposium was held under the auspices of the European Society of Car diology, and the scientific committee was recruited from members of the working groups on angina pectoris and coronary blood flow and on myocar dial function. The editors want to express many thanks to all those who contributed to the success of the symposium. W. Rutishauser H. Roskamm v List of Contributors R. Abbott Medical Center, School of Medicine, 720 Harrison Avenue, Boston, Massachusetts 02118, U.S.A.G.J. Anderson Heart Station, Likoff Cardiovascular Institute, Hahnemann University, School of Medicine, 230 N. Broad Street, Philadelphia, Pennsylvania 19102, U.S.A M.E. Bertrand Service de Cardiologie "B" et Hemodynamique, Hopital Cardiologique, 59037 Lille Cedex, France P. Betz Rehabilitationszentrum fur Herz- und Kreislaufkranke, Slidring 15, 7812 Bad Krozingen, FRG W. Bleifeld Abt. fur Kardiologie, II. Medizinische Klinik, Univ.-Krankenhaus Eppendorf, Martinistr. 52,2000 Hamburg 20, FRG D.A. Bragg-Remschel Texas Heart Institute, Texas Children's Hospital, P.O. Box 20269, Houston, Texas 77225, U.S.A.R.W Brower Thoraxcentrum/Cardiologie, Academisch Ziekenhuis, Dr. Molewaterplein 40,3015 GD Rotterdam, Netherlands E.J. Brown, Jr. Cardiology Division, Dept. of Medicine. Health Sciences Center, State University of New York, Stony Brook, New York 11794, U.S.A.
Coronary Circulation And Myocardial Ischemia
DOWNLOAD
Author : Michael R. Pinsky
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Coronary Circulation And Myocardial Ischemia written by Michael R. Pinsky and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
The coronary circulation is central to sustaining myocardial viability. Unlike the cir culations of most other organs, if the coronary circulation becomes insufficient to sustain myocardial contractile function, overall quality of life rapidly declines and life can abruptly end. In partnership with the cerebral circulation, the coronary circula tion plays a central role in sustaining life. However, unlike the cerebral circulation, whose function is self-sufficient to define life, the coronary circulation determines global blood flow and thus the initial state for the remainder of the body. This unique condition, together with the reality that coronary artery disease primarily affects peo ple in their productive years of life, has allowed physicians and scientists who study the heart to enjoy a privileged position in the field of medical research and clinical practice. Thus, it comes as little surprise that many new and exciting research developments involving the coronary circulation have recently come to the forefront of medical thinking. This reality, coupled with the large number of clinical trials of agents specif ically designed to sustain or improve coronary flow in many disease states, makes the timing of this monograph relevant. The book features papers presented at a recent international symposium, the fourth in a series of meetings on Applied Physiology of the Peripheral Circulation. The papers selected by the editors review the most impor tant advances in the fields of cardiology and the coronary circulation.
Myocardial Ischemia And Lipid Metabolism
DOWNLOAD
Author : R. Ferrari
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Myocardial Ischemia And Lipid Metabolism written by R. Ferrari and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Over the past years, the thrust of research in cardiology has been toward an understanding of the engineering of the heart as a pump that transports blood to the various organs of the body. More recently, the fields of biochemistry and biophysics have come to influence heart research. The modern cardiologist can no longer pretend to understand, for example, what is happening to the patient with myocardial infarction or ischemia without understanding the principles of molecular biology. The structure and function of the heart are therefore central themes of cardiological research and practice, which incorporate knowledge and discoveries from diverse disciplines. The importance of lipid metabolism in the myocardium has become clearly understood. In the well-oxygenated heart, fatty acids are the preferred substrates. The fact that the heart derives most of its energy from the oxidation of lipids, which represent the larg est energy store of the body, is logical for an organ that must work throughout our lifetime. There are, however, several lines of evidence that during ischemia, lipids may. be harmful to the heart. High levels of free fatty acids in the serum have been suggested to play a role in causing life-threatening arryhthmias and damage in the ischemic heart. The molecular basis for these effects remains poorly understood, and several possible mechanisms for these harm ful effects have been suggested.
Cardiac Ischemia From Injury To Protection
DOWNLOAD
Author : Bohuslav Ost'ádal
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-09
Cardiac Ischemia From Injury To Protection written by Bohuslav Ost'ádal and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-09 with Medical categories.
Cardiac Ischemia: From Injury to Protection has been divided into six parts. The first part describes the differences between hypoxia and ischemia, animal models, the effects of ischemia on myocardial function and metabolism, and the electrophysiological consequences of ischemia. The second part deals with the mechanisms of cardiomyocyte death in ischemia, structural aspects of irreversible ischemic injury, necrosis and apoptosis of cardiac cells, the role of calcium, and the concept of calcium antagonism. The third chapter is a brief description of reperfusion injury, its clinical relevance, and possible prevention. The fourth part summarizes changes in myocardial vasculature during ischemia and reperfusion. The fifth part is the survey of two main possibilities for increasing cardiac resistance to ischemia and hypoxia, i.e. long-lasting adaptation to chronic hypoxia and short-lasting preconditioning. The last part of the book deals with comparative and ontogenetic aspects of cardiac sensitivity to oxygen deprivation; this chapter also summarizes the ontogenetic differences and limitations in endogenous and exogenous protection of the ischemic/hypoxic heart.