Nanopore Long Read Variant Calling
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Next Generation Sequencing Data Analysis
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Author : Xinkun Wang
language : en
Publisher: CRC Press
Release Date : 2023-07-06
Next Generation Sequencing Data Analysis written by Xinkun Wang and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-07-06 with Mathematics categories.
RNA-seq: both bulk and single-cell (separate chapters) Genotyping and variant discovery through whole genome/exome sequencing Clinical sequencing and detection of actionable variants De novo genome assembly ChIP-seq to map protein-DNA interactions Epigenomics through DNA methylation sequencing Metagenome sequencing for microbiome analysis
Advances In Molecular Pathology
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Author : Gregory J. Tsongalis
language : en
Publisher: Elsevier Health Sciences
Release Date : 2023-10-18
Advances In Molecular Pathology written by Gregory J. Tsongalis and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-10-18 with Medical categories.
Advances in Molecular Pathology reviews the year’s most important findings and updates within the field in order to provide molecular pathologists with the current clinical information they need to improve patient outcomes. A distinguished editorial board, led by Dr. Gregory Tsongalis, identifies key areas of major progress and controversy and invites preeminent specialists to contribute original articles devoted to these topics. These insightful overviews in molecular pathology inform and enhance clinical practice by bringing concepts to a clinical level and exploring their everyday impact on patient care. Provides in-depth, clinical reviews in molecular pathology, providing actionable insights for clinical practice. Presents the latest information in the field under the leadership of an experienced editorial team. Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews.
Advancements In Molecular Diagnosis And Treatment Of Melanoma
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Author : Giuseppe Palmieri
language : en
Publisher: Frontiers Media SA
Release Date : 2021-09-13
Advancements In Molecular Diagnosis And Treatment Of Melanoma written by Giuseppe Palmieri and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-09-13 with Medical categories.
Single Cell Transcriptomics
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Author : Raffaele A. Calogero
language : en
Publisher: Springer Nature
Release Date : 2022-12-10
Single Cell Transcriptomics written by Raffaele A. Calogero and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-12-10 with Science categories.
This volume provides up-to-date methods on single cell wet and bioinformatics protocols based on the researcher experiment requirements. Chapters detail basic analytical procedures, single-cell data QC, dimensionality reduction, clustering, cluster-specific features selection, RNA velocity, multi-modal data integration, and single cell RNA editing. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and comprehensive, Single Cell Transcriptomics: Methods and Protocols aims to be a valuable resource for all researchers interested in learning more about this important and developing field.
Nanopore Sequencing
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Author : Kazuharu Arakawa
language : en
Publisher: Springer Nature
Release Date : 2023-02-14
Nanopore Sequencing written by Kazuharu Arakawa and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-02-14 with Science categories.
This volume provides comprehensive dry and wet experiments, methods, and applications on nanopore sequencing. Chapters guide readers through bioinformatic procedures, genome sequencing, analysis of repetitive regions, structural variations, rapid and on-site microbial identification, epidemiology, and transcriptome analysis. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and methods, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and cutting-edge, Nanopore Sequencing: Methods and Protocols aims to be comprehensive guide for researchers.
Big Data Analysis And Artificial Intelligence For Medical Sciences
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Author : Paola Lecca
language : en
Publisher: John Wiley & Sons
Release Date : 2024-07-29
Big Data Analysis And Artificial Intelligence For Medical Sciences written by Paola Lecca and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-07-29 with Medical categories.
Big Data Analysis and Artificial Intelligence for Medical Sciences Overview of the current state of the art on the use of artificial intelligence in medicine and biology Big Data Analysis and Artificial Intelligence for Medical Sciences demonstrates the efforts made in the fields of Computational Biology and medical sciences to design and implement robust, accurate, and efficient computer algorithms for modeling the behavior of complex biological systems much faster than using traditional modeling approaches based solely on theory. With chapters written by international experts in the field of medical and biological research, Big Data Analysis and Artificial Intelligence for Medical Sciences includes information on: Studies conducted by the authors which are the result of years of interdisciplinary collaborations with clinicians, computer scientists, mathematicians, and engineers Differences between traditional computational approaches to data processing (those of mathematical biology) versus the experiment-data-theory-model-validation cycle Existing approaches to the use of big data in the healthcare industry, such as through IBM’s Watson Oncology, Microsoft’s Hanover, and Google’s DeepMind Difficulties in the field that have arisen as a result of technological changes, and potential future directions these changes may take A timely and up-to-date resource on the integration of artificial intelligence in medicine and biology, Big Data Analysis and Artificial Intelligence for Medical Sciences is of great benefit not only to professional scholars, but also MSc or PhD program students eager to explore advancement in the field.
Computational Methods For Precision Oncology
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Author : Alessandro Laganà
language : en
Publisher: Springer Nature
Release Date : 2022-03-01
Computational Methods For Precision Oncology written by Alessandro Laganà and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-03-01 with Medical categories.
Precision medicine holds great promise for the treatment of cancer and represents a unique opportunity for accelerated development and application of novel and repurposed therapeutic approaches. Current studies and clinical trials demonstrate the benefits of genomic profiling for patients whose cancer is driven by specific, targetable alterations. However, precision oncologists continue to be challenged by the widespread heterogeneity of cancer genomes and drug responses in designing personalized treatments. Chapters provide a comprehensive overview of the computational approaches, methods, and tools that enable precision oncology, as well as related biological concepts. Covered topics include genome sequencing, the architecture of a precision oncology workflow, and introduces cutting-edge research topics in the field of precision oncology. This book is intended for computational biologists, bioinformaticians, biostatisticians and computational pathologists working in precision oncology and related fields, including cancer genomics, systems biology, and immuno-oncology.
Embec Nbc 2017
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Author : Hannu Eskola
language : en
Publisher: Springer
Release Date : 2017-06-12
Embec Nbc 2017 written by Hannu Eskola and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-06-12 with Technology & Engineering categories.
This volume presents the proceedings of the joint conference of the European Medical and Biological Engineering Conference (EMBEC) and the Nordic-Baltic Conference on Biomedical Engineering and Medical Physics (NBC), held in Tampere, Finland, in June 2017. The proceedings present all traditional biomedical engineering areas, but also highlight new emerging fields, such as tissue engineering, bioinformatics, biosensing, neurotechnology, additive manufacturing technologies for medicine and biology, and bioimaging, to name a few. Moreover, it emphasizes the role of education, translational research, and commercialization.
Variant Calling
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Author : Charlotte Ng
language : en
Publisher: Springer Nature
Release Date : 2022-06-25
Variant Calling written by Charlotte Ng and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-06-25 with Science categories.
This volume provides practical guidance on a variety of techniques and steps to ensure successful variant calling. Chapters detail methods for variant calling from single-nucleotide variants to structural variants, variant calling in specialized data types such as RNA-seq and UMI-tagged sequencing, alignment-free genotyping and SNP calling, variant detection in single-cell DNA sequencing data, variant annotation, and preanalytical quality control to ensure successful variant calling. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists step-by-step protocol to execute the algorithms, describes the input and output data, and includes tips on troubleshooting and known pitfalls. Authoritative and cutting-edge, Variant Calling: Methods and Protocols aims to be a foundation for future studies and to be a source of inspiration for new investigations in the field.
Haplotyping
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Author : Brock A. Peters
language : en
Publisher: Springer Nature
Release Date : 2022-11-06
Haplotyping written by Brock A. Peters and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-11-06 with Science categories.
This book aims to be an introduction to haplotype information for both the wet and dry labs. Chapters detail co-barcoding and linked-reads based methods, third generation sequencing based methods, Hi-C based methods, single-cell and Strand-seq, and methods for using haplotype data once obtained. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Haplotyping: Methods and Protocols aims to provide compréhensive and accessible methods to undergraduate, graduate, and established scientists.