Network Pharmacology And Traditional Medicine
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Network Pharmacology And Traditional Medicine
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Author : Shao Li
language : en
Publisher: Frontiers Media SA
Release Date : 2020-10-08
Network Pharmacology And Traditional Medicine written by Shao Li and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-10-08 with Medical categories.
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Network Pharmacology And Traditional Medicine Setting The New Standards By Combining In Silico And Experimental Work
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Author : Shao Li
language : en
Publisher: Frontiers Media SA
Release Date : 2022-11-24
Network Pharmacology And Traditional Medicine Setting The New Standards By Combining In Silico And Experimental Work written by Shao Li and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-11-24 with Science categories.
Network Pharmacology
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Author : Shao Li
language : en
Publisher: Springer Nature
Release Date : 2021-09-29
Network Pharmacology written by Shao Li and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-09-29 with Medical categories.
This book introduces “network pharmacology” as an emerging frontier subject of systematic drug research in the era of artificial intelligence and big data. Network Pharmacology is an original subject of fusion system biology, bioinformatics, network science and other related disciplines. It emphasizes on starting from the overall perspective of the system level and biological networks, the analysis of the laws of molecular association between drugs and their treatment objects, reveals the systematic pharmacological mechanisms of drugs, and guides the research and development of new drugs and clinical diagnosis and treatment. After it was proposed, network pharmacology has been paid attention by researchers, and it has been rapidly developed and widely used. In order to systematically reveal the biological basis of diagnosis and treatment in traditional Chinese medicine and modern medicine, we proposed a new concept of "network target" for the first time, which has become the core theory of "network pharmacology". The core principle of a network target is to construct a biological network that can be used to decipher complex diseases. The network is then used as the therapeutic target, to which multicomponent remedies are applied. This book mainly includes four parts: 1) The concept and theory of network pharmacology; 2) Common analysis methods, databases and software in network pharmacological research; 3) Typical cases of traditional Chinese medicine modernization and modern drug research based on network pharmacology; 4) Network pharmacology practice process based on drugs and diseases.
Network Pharmacology And Traditional Chinese Medicine
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Author : Qihe Xu
language : en
Publisher:
Release Date : 2012
Network Pharmacology And Traditional Chinese Medicine written by Qihe Xu and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with Medicine categories.
Network Pharmacology and Traditional Chinese Medicine.
Chapter Network Pharmacology And Traditional Chinese Medicine
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Author : Qihe Xu
language : en
Publisher:
Release Date : 2012
Chapter Network Pharmacology And Traditional Chinese Medicine written by Qihe Xu and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with categories.
Integrative Pharmacology Based Research On Traditional Medicine Methodologies Medical And Pharmacological Applications
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Author : Hai Yu Xu
language : en
Publisher: Frontiers Media SA
Release Date : 2023-09-19
Integrative Pharmacology Based Research On Traditional Medicine Methodologies Medical And Pharmacological Applications written by Hai Yu Xu and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-09-19 with Science categories.
ntegrative Pharmacology can be used to determine the multi-pharmacological effects of traditional medicines such as traditional Chinese medicine (TCM), Kampo, Sa-sang, Ayurveda, etc.). Through qualitative and quantitative pharmacokinetic-pharmacodynamic (PK-PD) correlations among multi-constituents and multi-targets, integrating chemical profiling, ADME/PK processes, molecular network calculation and resulting experimental validation, the use of Integrative Pharmacology has become widespread. The data has provided a novel paradigm to evaluate the druggability of bioactive ingredients of herbs or formulae, to decipher the pharmacological mechanisms of drug action and to screen potentially new indications for approved drugs and previously unidentified adverse events. On this basis, Integrative Pharmacology may offer an effective way to test the potential scientific basis for traditional medicines and to assess what roles of traditional medicine can and cannot play in pharmaceuticals.
Systems Pharmacology And Traditional Chinese Medicine
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Author : Aiping Lu
language : en
Publisher: Frontiers Media SA
Release Date : 2021-06-23
Systems Pharmacology And Traditional Chinese Medicine written by Aiping Lu and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-06-23 with Science categories.
Network Pharmacology
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Author : Hector Oat
language : en
Publisher:
Release Date : 2023
Network Pharmacology written by Hector Oat and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023 with Herbs categories.
Network Pharmacology (NP) is a research method that utilises artificial intelligence (AI) and computational models has in recent year been utilised as a tool for research in herbal medicine (HM). For years HM research methods have has faced many drawbacks on how to capture the complexity and synergy of the phytoconstituents in herbal medicine, herb-herb interactions and herb-drug interactions due to the limitations of the reductionist approach of the biomedical paradigm of research. NP offers an approach to research that can accommodate multiple herbal components and multiple targets whereby computational models elucidate potential interactions and areas for further research. Hence this paper poses the questions: “How and to what extent is Network Pharmacology a useful research method for Herbal Medicine research?” To answer this question a systemic review of literature of the methods was carried out. It was found that while NP is a fertile concept for the future of HM and traditional medicine systems research, there are limitations. As a budding new research method for HM, NP lacks standardization and databases used to train AI models are slow to update and can be open access enabling a high chance for misinformation to be created. A conclusion that NP is an approach that utilises various methods rather than a research method in itself is drawn, defining a call for mixed methods in HM research. To that extent, NP is a very important concept for the future of HM research.
Network Pharmacology Drug Discovery And Development
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Author : Brianna Willis
language : en
Publisher: American Medical Publishers
Release Date : 2023-09-26
Network Pharmacology Drug Discovery And Development written by Brianna Willis and has been published by American Medical Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-09-26 with Medical categories.
Network pharmacology reveals pharmacological mechanisms of drugs for outlining the development and discovery of drugs along with clinical treatment. It combines clinical, experimental and computational investigation, while creating favorable conditions for investigating the features of traditional medicine. The aim of network pharmacology is to reveal and reflect on the biological foundations of various complex diseases and effects of drugs by the application of network based understanding. It is useful in drug discovery and development, as it combines system biology and genomic technologies through computational biological tools. It is capable of elucidating complex relations amidst biological systems, diseases and drugs. It emphasizes on systems level modeling of mechanism of drugs, by integrating protein-protein interaction, drug-target interaction along with other type of interactome data. This book explores all the important aspects of network pharmacology in the present day scenario. It presents researches and studies performed by experts across the globe. As this field is emerging at a rapid pace, the contents of this book will help the readers to understand drug discovery and development within network pharmacology.
Traditional Chinese Medicine And Clinical Pharmacology
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Author : Anita Chen Marshall
language : en
Publisher:
Release Date : 2020
Traditional Chinese Medicine And Clinical Pharmacology written by Anita Chen Marshall and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020 with Acupuncture categories.
Traditional Chinese Medicine (TCM) represents thousands of years in treatment protocols for health, healing, and longevity and has evolved into a complex healthcare system. The following chapter is designed to give a basic concise overview of TCM principles and practices, in relation to clinical pharmacology, and focuses on mutually relevant areas of interest. Much as society learned to harness electrical currents to empower machinery, TCM theories of energetic patterns help to empower the functionality of the human body. The major theories include the vital life force, known as Qi, Yin and Yang, Five Elements, herbal medicine, multivariate diagnostics, syndrome differentiation, and acupuncture, among others. In TCM, there is a direct relationship to the energy of nature and the energetic patterns within the human body and the human consciousness. This comprehensive approach is gaining momentum in clinical and network pharmacology, as new technologies emerge regarding TCM collaborative compounds versus singular chemical constituents in treatment modalities. Of major importance to clinical pharmacology are recent TCM evidenced-based empirical studies, correlations, and interactions between herbs and pharmaceuticals, updated data on toxicity, adverse reactions, quality assurance, and herbal medicine standardization. Global concerns over antimicrobial resistance to drugs have put a spotlight on TCM herbal medicines as alternatives with greatly reduced resistance factors. From ancient archives to the Nobel Prize to a formal endorsement by the World Health Organization as a global healthcare system, TCM has widened the lens of modern science. It offers the wisdom and experience of millennia to inspire the think tank of today’s medicine and pharmacology and tomorrow’s generations of integrative healthcare advancements.