Neurotransmitters In The Human Brain
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Neurotransmitters In The Human Brain
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Author : David J. Tracey
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Neurotransmitters In The Human Brain written by David J. Tracey and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
The study of neurotransmitters in the human brain has expanded spectacularly in recent years with the application of techniques from immunology and molecular biology. These techniques are now being used successfully to help decipher the chemical architecture of the human nervous system. The results of these studies are of great importance for the understanding and treatment of neurological and psychiatric disorders such as Alzheimer's, Parkinson's and Huntington's diseases, as well as depression and schizophrenia. Professor Istvan Tork was a pioneer in the chemical anatomy of the brain and carried out important studies on the neuroanatomy and distribution of neuropeptides and monoarnines in the brain; some of his best known work dealt with the dual innervation of the cortex by neurons containing serotonin. Istvan Tork died on November 21, 1992, after a long struggle with a temporal lobe glioma, leaving a profound legacy of friendship and scholarly work 1. It was decided by the editors of this volume to commemorate his work and the mentors hip he gave to his many students by convening a symposium on neurotransmitters in the human brain. The symposium was held at the University of New South Wales on February 5, 1994, and was attended by over one hundred participants, including many of Professor Tork's colleagues and students. The papers from this symposium are presented in this volume to stand as a tribute to the breadth and quality of his work and to the energy and achievement of his students.
Neurotransmitters And The Human Brain
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Author : Floyd E. Bloom
language : en
Publisher:
Release Date : 1986
Neurotransmitters And The Human Brain written by Floyd E. Bloom and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1986 with categories.
Receptors In The Human Nervous System
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Author : F. A. O. Mendelsohn
language : en
Publisher: Academic Press
Release Date : 2013-10-22
Receptors In The Human Nervous System written by F. A. O. Mendelsohn and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-22 with Medical categories.
Receptors in the Human Nervous System is a synthesis of the results of receptor mapping by leaders in the field. In addition to a comprehensive discussion of the distribution and possible interactions of the receptors of different neuroactive substances, this book also contains an abundance of pictorial representations of receptor distributions. High-quality photographs of one receptor are often juxtaposed with photographs of the distribution of a different receptor or receptor subtype for the consideration of possible interactions between different systems. The book surveys the distribution of receptor subtypes for the classical monoamine transmitters (acetylcholine, adrenaline, noradrenaline and serotonin) as well as the distribution of receptors for the excitatory and inhibitory amino acids, (glutamate, GABA and benzodiazepines) as well as the opioid peptides, angiotensen and other neuropeptides. The distribution of multiple types of serotonin receptors is given in detail, and the codistribution of receptors in the cortex is discussed. The book is directed toward researchers in the field of chemical neuroanatomy, as well as pharmacologists, neurophysiologists, and neuroscientists.
Discovering The Brain
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Author : National Academy of Sciences
language : en
Publisher: National Academies Press
Release Date : 1992-01-01
Discovering The Brain written by National Academy of Sciences and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992-01-01 with Medical categories.
The brain ... There is no other part of the human anatomy that is so intriguing. How does it develop and function and why does it sometimes, tragically, degenerate? The answers are complex. In Discovering the Brain, science writer Sandra Ackerman cuts through the complexity to bring this vital topic to the public. The 1990s were declared the "Decade of the Brain" by former President Bush, and the neuroscience community responded with a host of new investigations and conferences. Discovering the Brain is based on the Institute of Medicine conference, Decade of the Brain: Frontiers in Neuroscience and Brain Research. Discovering the Brain is a "field guide" to the brainâ€"an easy-to-read discussion of the brain's physical structure and where functions such as language and music appreciation lie. Ackerman examines: How electrical and chemical signals are conveyed in the brain. The mechanisms by which we see, hear, think, and pay attentionâ€"and how a "gut feeling" actually originates in the brain. Learning and memory retention, including parallels to computer memory and what they might tell us about our own mental capacity. Development of the brain throughout the life span, with a look at the aging brain. Ackerman provides an enlightening chapter on the connection between the brain's physical condition and various mental disorders and notes what progress can realistically be made toward the prevention and treatment of stroke and other ailments. Finally, she explores the potential for major advances during the "Decade of the Brain," with a look at medical imaging techniquesâ€"what various technologies can and cannot tell usâ€"and how the public and private sectors can contribute to continued advances in neuroscience. This highly readable volume will provide the public and policymakersâ€"and many scientists as wellâ€"with a helpful guide to understanding the many discoveries that are sure to be announced throughout the "Decade of the Brain."
Neurotransmitter Transporters
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Author : Maarten E. A. Reith
language : en
Publisher: Springer Science & Business Media
Release Date : 1996-10-01
Neurotransmitter Transporters written by Maarten E. A. Reith and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996-10-01 with Medical categories.
A comprehensive survey of recent advances made in characterizing neurotransmitter transporters-including their imaging in the living brain-and in elucidating the processes underlying biological transport. The expert contributors present up-to-date findings on the molecular cloning of transporters and on neurotransmitter families both in plasma membranes and in storage vesicles. They also provide essential information on the structure-activity relationships for a multitude of recently synthesized dopamine uptake blockers, on transporter changes in the context of human drug abuse, and on the role of transporters in the action of uptake blockers in vivo. The book opens the new frontier of transporters research, authoritatively presenting new insights into their roles in such diseases as brain ischemia and ALS, and into their involvement as targets for antidepressants, antiepileptics, drugs of abuse, and neurotoxins.
Neurotransmitter And Peptide Localization In Human Brain
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Author : Victoria Chan-Palay
language : en
Publisher:
Release Date : 1990
Neurotransmitter And Peptide Localization In Human Brain written by Victoria Chan-Palay and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1990 with categories.
Studies utilizing human brain tissue examined the colocalozation of neurotransmitters using immunocytochemical and in vitro hybridization techniques. Results have shown the coexistance of somatostatin and neuropeptide Y in the hippocampus, and galanin and acetylcholine in the human forebrain. Keywords: Biochemistry; Neurotransmitters. (KT).
The Role Of Protein And Amino Acids In Sustaining And Enhancing Performance
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Author : Institute of Medicine
language : en
Publisher: National Academies Press
Release Date : 1999-09-15
The Role Of Protein And Amino Acids In Sustaining And Enhancing Performance written by Institute of Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999-09-15 with Technology & Engineering categories.
It is a commonly held belief that athletes, particularly body builders, have greater requirements for dietary protein than sedentary individuals. However, the evidence in support of this contention is controversial. This book is the latest in a series of publications designed to inform both civilian and military scientists and personnel about issues related to nutrition and military service. Among the many other stressors they experience, soldiers face unique nutritional demands during combat. Of particular concern is the role that dietary protein might play in controlling muscle mass and strength, response to injury and infection, and cognitive performance. The first part of the book contains the committee's summary of the workshop, responses to the Army's questions, conclusions, and recommendations. The remainder of the book contains papers contributed by speakers at the workshop on such topics as, the effects of aging and hormones on regulation of muscle mass and function, alterations in protein metabolism due to the stress of injury or infection, the role of individual amino acids, the components of proteins, as neurotransmitters, hormones, and modulators of various physiological processes, and the efficacy and safety considerations associated with dietary supplements aimed at enhancing performance.
Histamine In The Brain
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Author : Jian-Sheng Lin
language : en
Publisher: Frontiers Media SA
Release Date : 2015-03-18
Histamine In The Brain written by Jian-Sheng Lin and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-03-18 with Brain categories.
Brain aminergic pathways are organized in parallel and interacting systems, which support a range of functions, from homoeostatic regulations to cognitive, and motivational processes. Despite overlapping functional influences, dopamine, serotonin, noradrenaline and histamine systems provide different contributions to these processes. The histaminergic system, long ignored as a major regulator of the sleep-wake cycle, has now been fully acknowledged also as a major coordinator of attention, learning and memory, decision making. Although histaminergic neurons project widely to the whole brain, they are functionally heterogeneous, a feature which may provide the substrate for differential regulation, in a region-specific manner, of other neurotransmitter systems. Neurochemical preclinical studies have clearly shown that histamine interacts and modulates the release of neurotransmitters that are recognized as major modulators of cognitive processing and motivated behaviours. As a consequence, the histamine system has been proposed as a therapeutic target to treat sleep-wake disorders and cognitive dysfunctions that accompany neurodegenerative and neuroinflammatory pathologies. Last decades have witnessed an unexpected explosion of interest in brain histamine system, as new receptors have been discovered and selective ligands synthesised. Nevertheless, the complete picture of the histamine systems fine-tuning and its orchestration with other pathways remains rather elusive. This Research Topic is intended to offer an inter-disciplinary forum that will improve our current understanding of the role of brain histamine and provide the fundamentals necessary to drive innovation in clinical practice and to improve the management and treatment of neurological disorders.
Sculptor And Destroyer
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Author : Mark Paul Mattson
language : en
Publisher:
Release Date : 2023
Sculptor And Destroyer written by Mark Paul Mattson and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023 with Glutamic acid categories.
The fascinating story of glutamate, the neurotransmitter that controls the structure and function of the brain in health and neurological disorders. Sculptor and Destroyer tells the story of a simple, little-known molecule that became a master architect and commander of the human brain: glutamate. Upward of 90 percent of the neurons in the human brain deploy glutamate as their neurotransmitter. Other neurotransmitters can only exert their effects on brain function by subtly modifying the ongoing activity of glutamatergic neurons, but during brain development glutamate controls the growth of dendrites and the formation of synapses. In this eye-opening book, Mark Mattson explains how the neurotransmitter glutamate controls the structure and function of neuronal networks in the brain, thereby mediating the brain's capabilities, including learning and memory, creativity, and imagination. Mattson also delves deeply into the dark side of glutamate, which he calls the “destroyer” side. He shows how relatively subtle aberrancies in the activity of neurons that deploy glutamate may result in behavioral disorders ranging from autism and schizophrenia to chronic anxiety and depression. More dramatically, he describes how glutamate can excite neurons to death, a process that occurs in epilepsy and stroke and, perhaps even more insidiously, in Alzheimer's disease, Parkinson's disease, ALS, and Huntington's disease. Sculptor and Destroyer concludes with a perspective on how knowledge of glutamate's roles in neuroplasticity might be applied to the optimization of brain health throughout our lives. Written in engaging, approachable prose, Sculptor and Destroyer will be of interest to anyone in the fields of neuroscience, neurology, psychiatry, and psychology, as well as to anyone with a curiosity about the human brain.
Sites Of Drug Action In The Human Brain
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Author : Anat Biegon
language : en
Publisher: CRC Press
Release Date : 2020-02-06
Sites Of Drug Action In The Human Brain written by Anat Biegon and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-02-06 with Medical categories.
Sites of Drug Action in the Human Brain uses the results of recent analyses of the regional brain distribution and binding pattern of drugs in the human brain. This new book specifically addresses drugs of abuse and treats the effects of various drugs on behavior and mood, as well as on metabolism and blood flow in the human brain. It also presents the methodological aspects of investigating the sites of drug action in the human brain. Because it focuses on the living human brain, this book differs from other books on the subject, which primarily use the results of postmortem studies. Sites of Drug Action in the Human Brain therefore provides valuable information on the clinical aspects of drug intoxification, addiction, and toxicity.