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New Approaches To Stabilisation Of Vaccines Potency


New Approaches To Stabilisation Of Vaccines Potency
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New Approaches To Stabilisation Of Vaccines Potency


New Approaches To Stabilisation Of Vaccines Potency
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Author : Fred Brown
language : en
Publisher: S. Karger AG (Switzerland)
Release Date : 1996

New Approaches To Stabilisation Of Vaccines Potency written by Fred Brown and has been published by S. Karger AG (Switzerland) this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996 with Medical categories.


Immunization is one of the most important tools in public health and, according to the World Bank, the most cost-effective intervention in medicine. Vaccines have to be developed, field-tested, licensed, produced, quality controlled, regulated, purchased, transported, stored and delivered. Vaccine stability is a crucial factor to ensure that the vaccine delivered to the child is safe and effective. This book reports the proceedings of an international conference organized by the International Association of Biological Standardization and representatives of WHO's Global Programme for Vaccines and Immunization to discuss technical and regulatory aspects of vaccine stability and ways to improve collaboration. Topics under consideration include vaccine transport and storage; problems with maintaining the cold chain, especially in developing countries; reasons for instability of existing vaccines, and recent developments in the design of viral, bacterial and parasite vaccines. The factors affecting vaccine stability are evaluated, and a large number of new approaches for vaccine stabilisation are presented. Comprehensive and up-to-date, this publication will be appreciated by anyone concerned with the development, production and distribution of vaccines.



Practical Aspects Of Vaccine Development


Practical Aspects Of Vaccine Development
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Author : Parag Kolhe
language : en
Publisher: Elsevier
Release Date : 2021-09-08

Practical Aspects Of Vaccine Development written by Parag Kolhe and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-09-08 with Business & Economics categories.


Formulation, Development and Manufacturing of Vaccines: The Practical Aspects provides an industry perspective on vaccine product development and manufacture that covers their formulation development, manufacture and delivery/in-use considerations of vaccine production. With the increasing complexity of vaccine products in development, there is a need for a comprehensive review of the current state of the industry and its challenges. While formulation scientists working in biotherapeutic development may be familiar with proteins, vaccines present unique challenges, including the wide range of vaccine components that may comprise proteins, polysaccharides, protein-polysaccharide conjugates, adjuvants, etc. and the varying stability and behavior of solution- and suspension-based systems. This book is an essential resource for formulation scientists, researchers in vaccine development throughout medical and life sciences, and advanced students. Includes formulation considerations for various vaccine types, including proteins, polysaccharides, conjugates and live vaccines Considers process development for solution, suspension and lyophilized products Explores the future potential of vaccines, including multi-component vaccines and novel delivery mechanisms/devices



Immunopotentiators In Modern Vaccines


Immunopotentiators In Modern Vaccines
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Author : Virgil Schijns
language : en
Publisher: Elsevier
Release Date : 2005-12-19

Immunopotentiators In Modern Vaccines written by Virgil Schijns and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-12-19 with Medical categories.


Immunopotentiators in Modern Vaccines provides an in-depth insight and overview of a number of most promising immunopotentiators in modern vaccines. In contrast to existing books on the subject it provides recent data on the critical mechanisms governing the activity of vaccine adjuvants and delivery systems. Knowledge of immunological pathways and scenarios of the cells and molecules involved is described and depicted in comprehensive illustrations. Contributions from leading international authorities in the field Well-illustrated, informative figures present the interactions between immunopotentiators and the host immune system Each chapter lists advantages and potential hurdles for achieving a practical application for the specific immunopentiator



Enzyme Technology


Enzyme Technology
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Author : Ashok Pandey
language : en
Publisher: Springer Science & Business Media
Release Date : 2006-04-28

Enzyme Technology written by Ashok Pandey and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-04-28 with Medical categories.


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Synthetic Peptides As Antigens


Synthetic Peptides As Antigens
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Author : S. Muller
language : en
Publisher: Elsevier
Release Date : 1999-11-25

Synthetic Peptides As Antigens written by S. Muller and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999-11-25 with Medical categories.


This newest edition to the Laboratory Techniques Series gives current state of the art use of synthetic peptides in molecular biology and practical protocols on how to conjugate peptides, immunize animals with peptides and monitor immune responses to peptides in vitro. It gives background information on antigenic specificity, prediction of antigenic sites in proteins and applications of peptides in immunology and virology, as probes in diagnosis and as vaccines. The book also describes antigenicity of proteins and methods to localize antigenic sites as well as methods for predicting epitoxes, and gives detailed protocols for peptide-carrier conjugation, immunization with peptides, and peptide immunoassays. The volume also describes typical use of antipeptide antibodies in molecular and cellular biology as well as the use of peptides in the diagnosis of viral infections and autoimmune diseases, and the use of peptides as potential synthetic vaccines. An excellent edition to an excellent series, available in hardbound and paperback.



Developments In Biological Standardization


Developments In Biological Standardization
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Author :
language : en
Publisher:
Release Date : 1997

Developments In Biological Standardization written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997 with Biological products categories.




Engineering And Manufacturing For Biotechnology


Engineering And Manufacturing For Biotechnology
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Author : M. Hofman
language : en
Publisher: Springer Science & Business Media
Release Date : 2001-05-31

Engineering And Manufacturing For Biotechnology written by M. Hofman and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-05-31 with Medical categories.


Early integration is the key to success in industrial biotechnology. This is as true when a selected wild-type organism is put to work as when an organism is engineered for a purpose. The present volume Engineering and Manufacturing for Biotechnology took advantage of the 9th European Congress on Biotechnology (Brussels, Belgium, July 11-15, 1999): in the topics handled and in the expertise of the contributors, the engineering science symposia of this congress offered just what was needed to cover the important topic of integration of process engineering and biological research. The editors have solicited a number of outstanding contributions to illustrate the intimate interaction between productive organisms and the numerous processing steps running from the initial inoculation to the packaged product. Upstream processing of the feed streams, selection of medium components, product harvesting, downstream processing, and product conditioning are just a few major steps. Each step imposes a number of important choices. Every choice is to be balanced against time to market, profitability, safety, and ecology.



Vaccines For The 21st Century


Vaccines For The 21st Century
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Author : Institute of Medicine
language : en
Publisher: National Academies Press
Release Date : 2001-02-21

Vaccines For The 21st Century written by Institute of Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-02-21 with Medical categories.


Vaccines have made it possible to eradicate the scourge of smallpox, promise the same for polio, and have profoundly reduced the threat posed by other diseases such as whooping cough, measles, and meningitis. What is next? There are many pathogens, autoimmune diseases, and cancers that may be promising targets for vaccine research and development. This volume provides an analytic framework and quantitative model for evaluating disease conditions that can be applied by those setting priorities for vaccine development over the coming decades. The committee describes an approach for comparing potential new vaccines based on their impact on morbidity and mortality and on the costs of both health care and vaccine development. The book examines: Lessons to be learned from the polio experience. Scientific advances that set the stage for new vaccines. Factors that affect how vaccines are used in the population. Value judgments and ethical questions raised by comparison of health needs and benefits. The committee provides a way to compare different forms of illness and set vaccine priorities without assigning a monetary value to lives. Their recommendations will be important to anyone involved in science policy and public health planning: policymakers, regulators, health care providers, vaccine manufacturers, and researchers.



Excipient Development For Pharmaceutical Biotechnology And Drug Delivery Systems


Excipient Development For Pharmaceutical Biotechnology And Drug Delivery Systems
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Author : Ashok Katdare
language : en
Publisher: CRC Press
Release Date : 2006-07-28

Excipient Development For Pharmaceutical Biotechnology And Drug Delivery Systems written by Ashok Katdare and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-07-28 with Medical categories.


To facilitate the development of novel drug delivery systems and biotechnology-oriented drugs, the need for new, yet to be developed, and approved excipients continues to increase. Excipient Development for Pharmaceutical, Biotechnology, and Drug Delivery Systems serves as a comprehensive source to improve understanding of excipients and forge potential new avenues for regulatory approval. This book presents detailed, up-to-date information on various aspects of excipient development, testing, and technological considerations for their use. It addresses specific details such as historical perspective, preclinical testing, safety, and toxicology evaluation, as well as regulatory, quality, and utility aspects. The text also describes best practices for use of various functional excipients and extensive literature references for all topics.



Vaccines And Diagnostics For Transboundary Animal Diseases


Vaccines And Diagnostics For Transboundary Animal Diseases
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Author : J.A. Roth
language : en
Publisher: Karger Medical and Scientific Publishers
Release Date : 2013-04-18

Vaccines And Diagnostics For Transboundary Animal Diseases written by J.A. Roth and has been published by Karger Medical and Scientific Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-04-18 with Medical categories.


Transboundary animal diseases (TADs) are a major threat to livestock. They are highly contagious or transmissible, and they have the potential to cause high morbidity and mortality in both susceptible animal populations and humans. In addition, not only are TADs detrimental to national economies, they are also a serious threat to world food security. This volume presents the proceedings of an international workshop on Vaccines and Diagnostics for Transboundary Animal Diseases that was held in Ames (Iowa, USA) in 2012. Experts and scientists from academia, industry and government reviewed the current status of vaccines and diagnostics for high priority TADs, decision-making and regulatory processes for veterinary biologics, and the roles and responsibilities of government agencies. The discussions also addressed achievements and gaps in vaccine and diagnostics development for 11 important TADs as well as the translation of research findings into licensed novel vaccines and diagnostics for high-priority TADs.