New Drugs In C Ncer Chemotherapy
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New Drugs In Cancer Chemotherapy
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Author : S.K. Carter
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-09
New Drugs In Cancer Chemotherapy written by S.K. Carter and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-09 with Medical categories.
The Analog Potential in Cancer Chemotherapy in the United States and Japan S. K. Carter Northern California Cancer Program, 1801 Page Mill Road, Building B, Suite 200, USA - Palo Alto, CA 94304 The bilateral collaborative program in cancer research between Japan and the United States is one of the oldest programs of this type. It is sponsored in the United States by the National Cancer Institute [1], while in Japan the sponsoring organization is the Japan Society for the Promotion of Science. Annual symposia concerning treatment have been held and in recent years they have been published [2, 3]. Drug development in both Japan and the United States has evolved over the years to an increasing emphasis on second generation compounds. This has come about as a result of the initial successes of chemotherapy development. Many active structures have been uncovered and the armamentarium of the medical and pediatric oncologist has grown dramatically. The uncovering of an active structure provides an opportunity for analog synthesis and attempts at elucidating structure-activity relationships. It is hoped that the therapeutic index of active structures can be improved so as to achieve superior clinical results.
New Drugs Concepts And Results In Cancer Chemotherapy
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Author : Franco M. Muggia
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
New Drugs Concepts And Results In Cancer Chemotherapy written by Franco M. Muggia and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
New Drugs In C Ncer Chemotherapy
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Author : Stephen K Carter
language : en
Publisher:
Release Date : 1981
New Drugs In C Ncer Chemotherapy written by Stephen K Carter and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1981 with categories.
Cancer Drug Discovery
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Author : Kyu-Won Kim
language : en
Publisher: Springer
Release Date : 2016-11-14
Cancer Drug Discovery written by Kyu-Won Kim and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-11-14 with Medical categories.
The reader will discover a comprehensive and multifaceted overview of the history of the development of anticancer drugs deeply influenced by the cell concept of cancer and future directions for the development of new anticancer drugs. First, this book documents the scientific progress in biological science over the last 70 years and the influence this progress had in cancer research. Summaries and charts of important discoveries complete this overview. Furthermore, this book outlines the process of anticancer drug development with a focus on the characteristic drug groups of each era, related to advancements of chemistry and biological sciences. This book also provides brief mechanism of action of drugs, illustrated by comprehensive timelines and conceptual cartoons. This book finally sums up the limitations of the current anticancer drug development and seeks new directions for anticancer drug discovery, considering under the systemic view of cancer.
New Drugs Concepts And Results In Cancer Chemotherapy
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Author : Franco M Muggia
language : en
Publisher:
Release Date : 1991-10-31
New Drugs Concepts And Results In Cancer Chemotherapy written by Franco M Muggia and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1991-10-31 with categories.
The Cancer Chemotherapy Handbook
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Author : David S. Fischer
language : en
Publisher:
Release Date : 1997
The Cancer Chemotherapy Handbook written by David S. Fischer and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997 with Medical categories.
Concisely written, yet comprehensive in scope, this new edition is a practical guide to the medical care and chemotherapeutic treatment of cancer patients. It is formatted for easy access to the more than 85 specific drugs currently used in cancer treatment. 12 illus.
Natural Products And Cancer Drug Discovery
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Author : Frank E. Koehn
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-11-09
Natural Products And Cancer Drug Discovery written by Frank E. Koehn and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-11-09 with Medical categories.
This volume will cover the natural products as they relate to cancer chemotherapy. The topics will include history and current status , recent launches, new clinical candidates and approved drugs directly derived from natural products, current and future cancer target opportunities for natural products, leveraging natural products as tools for new target generation , new approaches to cancer drug discovery through natural products based lead generation, and enabling technologies which leverage the unique attributes of natural products.
The Search For New Anticancer Drugs
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Author : Michael Waring
language : en
Publisher: Springer Science & Business Media
Release Date : 1992-11-30
The Search For New Anticancer Drugs written by Michael Waring and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992-11-30 with Medical categories.
Most of the anti-cancer drugs in use today were discovered by happy accident rather than design, yet the rational design of better anti-cancer drugs remains a cherished goal, and one of the most important challenges facing medical science. This book represents a compilation of views and progress reports which illustrate the diversity of approaches to the problem. Recent research has confirmed the belief that critical genetic changes are at work in cancer cells. The genome, then (DNA in biochemical terms), surely represents a critical target for specific chemotherapy of cancer, and several chapters address the issue of attacking DNA, gene targetting, and the like. Others deal with principles of rational design, exploitation of novel modalities and targets, or the nuts and bolts of antitumour drug testing. While no attempt has been made to provide a comprehensive coverage of this wide-ranging and vitally important subject, the present volume in the series will provide much food for thought.
Principles Of Cancer Treatment And Anticancer Drug Development
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Author : Wolfgang Link
language : en
Publisher: Springer Nature
Release Date : 2019-09-10
Principles Of Cancer Treatment And Anticancer Drug Development written by Wolfgang Link and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-09-10 with Medical categories.
This book explains how current medicines against cancer work and how we find new ones. It provides an easy-to-understand overview of current options to treat patients with cancer, which includes Surgery, Radiation therapy, Chemotherapy, Targeted therapy and Immunotherapy. The efficiency of all these treatments is limited by the capacity of cancer cells to escape therapy. This book explains the mechanisms of anti-cancer drug resistance and strategies to overcome it. The discovery and development process of a new drug is detailed beginning with the identification and validation of a therapeutic target, the identification of an inhibitor of the target and its subsequent preclinical and clinical development until its approval by regulatory authorities. Particular emphasis has been given to specific aspects of the development process including lead generation and optimization, pharmacokinetics, ADME analysis, pharmacodynamics, toxicity and efficacy assessment, investigational new drug (IND) and new drug application (NDA) and the design of clinical trial and their phases. The book covers many aspects of modern personalized oncology and discusses economic aspects of our current system of developing new medicines and its impact on our societies and on future drug research. The author of this book, Dr. Link counts with more than 20 years of experience in biomedical research reflected in numerous publications, patents and key note and plenary presentations at international conferences. Interested readers, students and teachers should read this book as it provides a unique way to learn/teach about basic concepts in oncology and anti-cancer drug research.
Principles Of Cancer Treatment And Anticancer Drug Development
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Author : Wolfgang Alexander Link
language : en
Publisher:
Release Date : 2019
Principles Of Cancer Treatment And Anticancer Drug Development written by Wolfgang Alexander Link and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019 with Cancer categories.
This book explains how current medicines against cancer work and how we find new ones. It provides an easy-to-understand overview of current options to treat patients with cancer, which includes Surgery, Radiation therapy, Chemotherapy, Targeted therapy and Immunotherapy. The efficiency of all these treatments is limited by the capacity of cancer cells to escape therapy. This book explains the mechanisms of anti-cancer drug resistance and strategies to overcome it. The discovery and development process of a new drug is detailed beginning with the identification and validation of a therapeutic target, the identification of an inhibitor of the target and its subsequent preclinical and clinical development until its approval by regulatory authorities. Particular emphasis has been given to specific aspects of the development process including lead generation and optimization, pharmacokinetics, ADME analysis, pharmacodynamics, toxicity and efficacy assessment, investigational new drug (IND) and new drug application (NDA) and the design of clinical trial and their phases. The book covers many aspects of modern personalized oncology and discusses economic aspects of our current system of developing new medicines and its impact on our societies and on future drug research. The author of this book, Dr. Link counts with more than 20 years of experience in biomedical research reflected in numerous publications, patents and key note and plenary presentations at international conferences. Interested readers, students and teachers should read this book as it provides a unique way to learn/teach about basic concepts in oncology and anti-cancer drug research.