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New Paradigms Of Coronary Artery Disease


New Paradigms Of Coronary Artery Disease
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New Paradigms Of Coronary Artery Disease


New Paradigms Of Coronary Artery Disease
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Author : G. Heusch
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-04-17

New Paradigms Of Coronary Artery Disease written by G. Heusch and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-04-17 with Medical categories.


Detailed analyses of regional myocardial blood flow, function, metabolism and morphology in ischemic and reperfused myocardium have led to the identifi cation of important phenomena, i. e. , myocardial hibernation, myocardial stun ning and ischemic preconditioning. Both the hibernating and the stunned myocardium characterize viable though dysfunctional as distinguished from necrotic tissue. With the advent of reperfusion procedures, the distinction between reversibly injured, hypofunctional myocardium from irreversibly injured, hypofunctional myocardium is of utmost clinical importance. The pathophysiological distinction of hibernating and stunned myocardium is con troversial, but reperfusion is mandatory anyway. Ischemic preconditioning is the most powerful maneuver known so far to delay infarct development. Its clinical significance has been suggested from retrospective analyses of data from patients suffering a myocardial infarction as well as from controlled PTCA studies. Whether or not preconditioning can be achieved pharmacologically in the clinical setting remains to be established. The mechanisms and signal cascade underlying myocardial hibernation, myocardial stunning and ischemic preconditioning are not clear in detail. Over the last year, focussed issues on myocardial hibernation, myocardial stunning and ischemic preconditioning were published in Basic Research in Car diology; they have received great interest and a good response. Therefore, these focussed issues are now combined and published as a separate monograph. We express our gratitude once more to all our colleagues who contributed to this monograph, to Ms. Ibkendanz of Steinkopff, and to Ms. Philipp and Mr. Heinrichs from Bayer AG Germany, who supported this additional publication.



New Treatment Paradigms In Unstable Coronary Artery Disease


New Treatment Paradigms In Unstable Coronary Artery Disease
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Author : Pierre Théroux
language : en
Publisher: Science Press Incorporated
Release Date : 2001-01-01

New Treatment Paradigms In Unstable Coronary Artery Disease written by Pierre Théroux and has been published by Science Press Incorporated this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-01-01 with Coronary heart disease categories.




Preventive Cardiology


Preventive Cardiology
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Author : JoAnne Micale Foody
language : en
Publisher: Springer Science & Business Media
Release Date : 2000-11-10

Preventive Cardiology written by JoAnne Micale Foody and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-11-10 with Medical categories.


Leading clinicians and researchers concisely review the significant risk factors, including dyslipidemias, hypertension, diabetes, lack of exercise, obesity, tobacco, and homocysteine, and outline the best preventive strategies available. They also offer an overview of the new paradigms in coronary artery disease pathophysiology, including the nature of the unstable atherosclerotic plaque, new strategies for the modification of plaque constituents, the importance of the endothelium in the maintenance of cardiovascular health, and the emerging roles of oxidative stress, infection, and inflammation. Comprehensive and pathbreaking, Preventive Cardiology: Strategies for the Prevention and Treatment of Coronary Artery Disease provides physicians with the understanding and tools necessary to bring the practice of preventive cardiology to their patients.



Preventive Cardiology


Preventive Cardiology
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Author : Jo Anne Micale Foody
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-11-03

Preventive Cardiology written by Jo Anne Micale Foody and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-11-03 with Medical categories.


Preventive cardiology is a fast moving field that places emphasis on the prevention and treatment of coronary disease. Preventive Cardiology: Insights Into the Prevention and Treatment of Cardiovascular Disease, Second Edition is intended for clinical cardio- gists, internists, primary care providers, and allied health care professionals who wish to extend their knowledge and expertise in the rapidly expanding field of preventive car- ology. It is the mission of this book to provide clinicians with the understanding and tools necessary to implement prevention in their daily practices. Recent changes in the delivery of health care in the United States and abroad, in conjunction with new scientific evidence supporting the role of preventive strategies in the maintenance of cardiovascular health, have focused new attention and efforts on the field of cardiovascular disease prevention. The field of cardiology is thus making a gradual transition from the technology-driven, intervention-oriented perspective of the last several decades to a new, preventive, molecular-based perspective. As fresh evidence amasses that preventive measures produce a considerable decrease in the incidence of both primary and secondary cardiac events and mortality, there is growing, widespread acknowledgment that health care providers from all arenas must initiate preventive str- egies in the management and care of their patients.



Asymptomatic Atherosclerosis


Asymptomatic Atherosclerosis
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Author : Morteza Naghavi
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-07-01

Asymptomatic Atherosclerosis written by Morteza Naghavi and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-07-01 with Medical categories.


Despite recent advances in the diagnosis and treatment of symptomatic atherosclerosis, available traditional screening methods for early detection and treatment of asymptomatic coronary artery disease are grossly insufficient and fail to identify the majority of victims prior to the onset of a life-threatening event. In Asymptomatic Atherosclerosis: Pathophysiology, Detection and Treatment, Dr. Morteza Naghavi and leading authorities from the Society for Heart Attack Prevention and Eradication (SHAPE) present a new paradigm for the screening and primary prevention of asymptomatic atherosclerosis. The text focuses on accurate, yet underutilized, measures of subclinical atherosclerosis, notably coronary artery calcium scanning and carotid intima-media thickness measurement. The authors introduce a comprehensive approach to identifying the vulnerable patients (asymptomatic individuals at risk of a near future adverse event). Additional chapters discuss future directions towards containing the epidemic of atherosclerotic cardiovascular disease using innovative solutions such as preemptive interventional therapies (bioabsorbable stents) for stabilization of vulnerable atherosclerotic plaques, mass unconditional Polypill therapy for population-based risk reduction, and ultimately vaccination strategies to prevent the development of atherosclerosis. Up-to-date and authoritative, Asymptomatic Atherosclerosis: Pathophysiology, Detection, and Treatment is a must-have for any cardiologist or primary care physician who wishes to practice modern preventive cardiology and manage the increasing number of asymptomatic atherosclerotic patients. Outlines more accurate measures of risk (coronary artery calcium and carotid intima-media thickness) than traditional risk factors (total cholesterol, LDL cholesterol, HDL cholesterol) Presents new multipronged strategies to aid in the early detection and treatment of high risk asymptomatic patients



Angiogenic Gene Therapy


Angiogenic Gene Therapy
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Author : Victor J. Dzau
language : en
Publisher:
Release Date : 2003

Angiogenic Gene Therapy written by Victor J. Dzau and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003 with categories.




Coronary Artery Disease


Coronary Artery Disease
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Author : Gregory W. Barsness
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-12-07

Coronary Artery Disease written by Gregory W. Barsness and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-12-07 with Medical categories.


A book directed towards individuals with an interest in the clinical treatment of patients with unrevascularizable angina. It explores the treatment options in the setting of a sound scientific background and provides guidance and predictions for future directions in this rapidly developing field. It is the only textbook of its kind and fulfils an unmet need for practicing internal medicine, family practice and cardiovascular clinicians. It also provides a reliable reference for clinical and basic researchers interested in this topic.



Chronic Coronary Artery Disease A Companion To Braunwald S Heart Disease E Book


Chronic Coronary Artery Disease A Companion To Braunwald S Heart Disease E Book
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Author : James de Lemos
language : en
Publisher: Elsevier Health Sciences
Release Date : 2017-01-03

Chronic Coronary Artery Disease A Companion To Braunwald S Heart Disease E Book written by James de Lemos and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-01-03 with Medical categories.


Featuring expert guidance from Drs. James de Lemos and Torbjørn Omland, as well as other globally known leaders in cardiology, Chronic Coronary Artery Disease covers every aspect of managing and treating patients suffering from chronic coronary syndromes. This brand-new companion to Braunwald's Heart Disease was designed as a stand-alone reference for physicians treating patients who present with complex, unique challenges, offering the latest information on the use of imaging modalities in diagnosis and treatment, advances in interventional and surgical approaches to revascularization, new medications to improve symptoms and outcomes in chronic CAD, and much more. Covers every aspect of evaluation and treatment of patients who suffer from chronic coronary syndromes. Provides both evidenced based recommendations from the most recent guidelines from the major cardiology societies: AHA, ACC, and ESC, as well as practical management tips from leading experts with extensive clinical experience. Highlights new developments concerning epidemiology and prevention, pathophysiology, and clinical findings, as well as laboratory testing, invasive and non-invasive testing, risk stratification, clinical decision-making, and prognosis and management of chronic coronary syndromes. Features information on today's hot topics, including the use of novel imaging modalities in diagnosis and treatment and emerging therapies to improve outcomes in chronic CAD.



Physiological Assessment Of Coronary Stenoses And The Microcirculation


Physiological Assessment Of Coronary Stenoses And The Microcirculation
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Author : Javier Escaned
language : en
Publisher: Springer
Release Date : 2017-08-10

Physiological Assessment Of Coronary Stenoses And The Microcirculation written by Javier Escaned and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-08-10 with Medical categories.


​Since the introduction of coronary angiography, a key technique in understanding coronary artery disease, a number of paradigms regarding its study and interpretation have taken place. Following an emphasis on improved angiographic and subsequent intracoronary imaging techniques, functional assessment of coronary circulation has demonstrated to have major implications for diagnosis and treatment of coronary artery disease. Fractional flow reserve, a pressure derived index of stenosis severity, constitutes the best example of the current importance of physiological assessment in clinical practice. However, the acceptance of FFR by cardiologists contrasts with important voids in knowledge on the basic principles of coronary physiology and of other available techniques that, as an alternative to FFR, allow a more comprehensive assessment of coronary circulation. This is particularly noticeable in the assessment of microcirculation, an unavoidable compartment of coronary circulation that is frequently affected in acute coronary syndromes of in the presence of cardiovascular risk factors or non-coronary heart disease. A deeper understanding of the relationship between epicardial vessel and microcirculatory involvement has started with the advent of newer imaging techniques like invasive optical coherence tomography, and non-invasive CT and NMR techniques. This book aims to be an indispensable tool for clinicians and researches in the field of coronary artery disease. It provides a balanced, comprehensive review of anatomy, physiology and available techniques, discusses both the diagnosis of epicardial vessel and microcirculatory disease, the impact of different diseases at different levels of coronary circulation, and the best way to address a separate or combined assessment of different levels of coronary circulation. ​



Angiogenic Gene Therapy


Angiogenic Gene Therapy
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Author : S. Ylä-Herttuala
language : en
Publisher:
Release Date : 2004

Angiogenic Gene Therapy written by S. Ylä-Herttuala and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with categories.