Newer Approaches To Heme Proteins
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Newer Approaches To Heme Proteins
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Author : Masao Kotani
language : en
Publisher:
Release Date : 1978
Newer Approaches To Heme Proteins written by Masao Kotani and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1978 with categories.
Newer Approaches To Heme Proteins
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Author :
language : en
Publisher:
Release Date : 1978
Newer Approaches To Heme Proteins written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1978 with Heme categories.
Advances In Biophysics
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Author :
language : en
Publisher:
Release Date : 1978
Advances In Biophysics written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1978 with categories.
The Smallest Biomolecules Diatomics And Their Interactions With Heme Proteins
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Author : Abhik Ghosh
language : en
Publisher: Elsevier
Release Date : 2011-10-13
The Smallest Biomolecules Diatomics And Their Interactions With Heme Proteins written by Abhik Ghosh and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-10-13 with Science categories.
This is not a book on NO biology, nor about hemoglobin, nor about heme-based sensors per se. Of course, it covers all these topics and more, but above all, it aims at providing a truly multidisciplinary perspective of heme-diatomic interactions. The overarching goal is to build bridges among disciplines, to bring about a meeting of minds. The contributors to this book hail from diverse university departments and disciplines – chemistry, biochemistry, molecular biology, microbiology, zoology, physics, medicine and surgery, bringing with them very different views of heme-diatomic interactions. The hope is that the juxtaposition of this diversity will lead to increased exchanges of ideas, approaches, and techniques across traditional disciplinary boundaries. The authors represent a veritable Who’s Who of heme protein research and include John Olson, Tom Spiro, Walter Zumft, F. Ann Walker, Teizo Kitagawa, W. Robert Scheidt, Pat Farmer, Marie-Alda Gilles-Gonzalez, and many other equally distinguished scientists. Extremely distinguished list of authors Multidisciplinary character – equally suitable for chemists and biochemists Covers the hottest topics in heme protein research: sensors, NO biology, new roles of hemoglobin, etc.
Newer Approaches To Heme Proteins
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Author : Masahiro Hatano
language : en
Publisher:
Release Date : 1978
Newer Approaches To Heme Proteins written by Masahiro Hatano and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1978 with Heme categories.
Heme And Hemoproteins
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Author : Francesco De Matteis
language : en
Publisher: Springer
Release Date : 1978
Heme And Hemoproteins written by Francesco De Matteis and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 1978 with Medical categories.
The study of the biological effects of foreign chemicals (whether therapeutic drugs or chemicals present at work or in the environment) interests the biologist from a number of different and complementary viewpoints. Apart from the more obvious pharmacological and toxicological interest, the experimentalist often uses foreign chemicals to produce in experimental animals disease states similar to naturally occurring diseases, so that their pathogenetic mechanisms and therapy can be studied under controlled conditions. In addition - as Claude Bernard pointed out over a century ago - foreign chemicals can be employed as instruments to analyze the most delicate vital processes; much can be learned about the physiological processes themselves by a careful study of the mechanisms by which these are altered by chemicals. The field of heme and hemoproteins offers an example of the interplay of these different approaches. Their metabolism can be altered by therapeutic drugs and other foreign chemicals and this results in a variety of biological responses that transcend the boundaries of pharmacology into the confines of clinical medi cine, genetics, toxicology, biochemistry and physiology. In this book a multidisciplinary approach to the study of heme metabolism is presented including the effect of chemicals on heme metabolism in patients, the results of experimental work in the whole animal, as well as in vitro studies.
Engineering Native And Artificial Heme C Containing Proteins For Biochemical Applications And Studies Of Protein Folding
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Author : Wesley B. Asher
language : en
Publisher:
Release Date : 2012
Engineering Native And Artificial Heme C Containing Proteins For Biochemical Applications And Studies Of Protein Folding written by Wesley B. Asher and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with categories.
"Heme c containing proteins are known for their intense colors and essential functions in nature. These proteins contain heme that is covalently bound to the protein. For part of the work in this thesis, we have developed fusion tags that contain heme c, known as heme-tags, that reversibly bind an L-histidine immobilized Sepharose (HIS) chromatography resin for affinity purification of recombinant proteins expressed in Escherichia coli. The heme-tag HIS purification method couples the ease of affinity purification with the convenience of visible detection for protein tracking. In addition, we show that the heme-tag can be used to quantify the protein. Heme is covalently bound to native heme c proteins by several dedicated biogenesis systems that exhibit a variable degree of diversity and substrate specificity. Heme-tagged proteins are produced using a biogenesis system native to E. coli with promiscuous substrate specificity. The biogenesis system that matures native mitochondrial cytochromes c (cyt c) that function in cellular respiration and apoptosis is referred to as cytochrome c heme lyase (CCHL). The substrate specificity of CCHL has been explored, but the details are unclear. In this thesis, we show that CCHL can mature the first 18 N-terminal residues of horse cyt c fused to a non-heme containing protein, which demonstrates that the C-terminal portion of cyt c is unimportant for substrate recognition. This work lends new insight into the substrate specificity of CCHL and provides a new approach for producing artificial heme c proteins that could find use in multiple applications. In addition to developing novel biochemical applications of the heme tag, we study the folding of the important model protein horse cyt c. Protein folding is considered one of the most confounding problems in science, and cyt c has long been a model protein to understand the general principles of folding. Herein, we show that the folding of cyt c is more complex than previously reported using single molecule fluorescence methods. We show evidence of multiple folding intermediates and pathways as the protein folds on its energy landscape"--Page v.
Hemeproteins Advances In Research And Application 2011 Edition
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Author :
language : en
Publisher: ScholarlyEditions
Release Date : 2012-01-09
Hemeproteins Advances In Research And Application 2011 Edition written by and has been published by ScholarlyEditions this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-01-09 with Medical categories.
Hemeproteins: Advances in Research and Application: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Hemeproteins. The editors have built Hemeproteins: Advances in Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Hemeproteins in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Hemeproteins: Advances in Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
New Approaches For Flavin Catalysis
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Author :
language : en
Publisher: Academic Press
Release Date : 2019-05-07
New Approaches For Flavin Catalysis written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-05-07 with Science categories.
New Approaches for Flavin Catalysis, Volume 620, a new volume in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Topics covered in this update include Anaerobiosis and Methods for Reduction, Reduction Potentials, Anaerobic Stopped-Flow, No Glove-Box, Anaerobic Stopped-Flow, in a Glove-Box, Chemical Quenching, Oxygen Reactions, Double-mixing Stopped-Flow, Kinetic Isotope Effects and Viscosity Effects, Heavy Enzymes Synthetic Flavins & Linear Free Energy Relationships, Vibrational Spectroscopy, Stark Spectroscopy, EPR and Related Methods, Molecular Dynamics, Phylogenetic Relationships/Superfamilies, O2 and Superoxide Analogs, and more. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Methods in Enzymology series Updated release includes the latest information on New Approaches for Flavin Catalysis
New Approaches To Highly Sterically Encumbered Porphyrins As Heme Active Sites
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Author : Chen-Yu Yeh
language : en
Publisher:
Release Date : 1999
New Approaches To Highly Sterically Encumbered Porphyrins As Heme Active Sites written by Chen-Yu Yeh and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999 with Binding sites (Biochemistry) categories.
