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Nimodipine


Nimodipine
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Nimodipine


Nimodipine
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Author : Alexander Scriabine
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Nimodipine written by Alexander Scriabine and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.


Proceedings of the Second International Symposium on Nimodipine, Miami Beach, Florida, USA, April 25-28, 1990



Nimodipine


Nimodipine
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Author : E. Betz
language : en
Publisher: F. K. Schattauer
Release Date : 1985-01-01

Nimodipine written by E. Betz and has been published by F. K. Schattauer this book supported file pdf, txt, epub, kindle and other format this book has been release on 1985-01-01 with Calcium categories.




Cardiopulmonary Effects Of Nimodipine After Subarachnoid Hemorrhage In Monkeys


Cardiopulmonary Effects Of Nimodipine After Subarachnoid Hemorrhage In Monkeys
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Author : Susan L. Norris
language : en
Publisher:
Release Date : 1984

Cardiopulmonary Effects Of Nimodipine After Subarachnoid Hemorrhage In Monkeys written by Susan L. Norris and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1984 with Cardiopulmonary system categories.


The objectives of this study were to examine the cardiopulmonary effects of subarachnoid hemorrhage, and of nimodipine used in a model of chronic cerebral vasospasm. In the first study 29 cynomolgus monkeys had a subarachnoid clot placed via a craniectomy. Five monkeys died in the first 24 hours after clot placement. Twenty-four monkeys survived and were started on the nimodipine trial. The survivors were divided into four equal groups in a double-blind fashion, and six animals were each given nimodipine 3 mg/kg po q8h, 6 mg/kg po q8h, and 12 mg/kg po q8h. The fourth group of monkeys received a placebo, polyethylene glycol 400 0.33 ml/kg q8h. Twenty-three animals completed the 1-week course of nimodipine, with one animal dying of septicemia. Four sets of cardiopulmonary indices were measured under general anesthesia: baseline (Stage I), pre- and post-clot placement (Stage II), and after receiving nimodipine for 7 days (Stage III). The acute cardiopulmonary effects of nimodipine were examined under general anesthesia. Oral nimodipine was given in doses of 20 mg/kg to two monkeys, 30 mg/kg to a third monkey, and 10 mg/kg to two cats. Intravenous nimodipine was administered in sequential doses of 0.012 mg/kg, 0.105 mg/kg, and 0.458 mg/kg to a monkey, and 0.010 mg/kg, 0.103 mg/kg and 0.517 mg/kg to a cat. Using an in vitro model of thermodilution cardiac output, volumetrically measured flows were compared to flows recorded by the Edwards' Cardiac Output Computer. Eighteen flows between 130 and 1035 ml/min were examined. Stage III indices were compared to Stage I for each treatment group. All groups had a fall in heart rate. Mean arterial pressure fell in the 12 mg/kg group (p



Nimodipine The Ultimate Step By Step Guide


Nimodipine The Ultimate Step By Step Guide
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Author : G. J. Blokdijk
language : en
Publisher: Createspace Independent Publishing Platform
Release Date : 2018-01-25

Nimodipine The Ultimate Step By Step Guide written by G. J. Blokdijk and has been published by Createspace Independent Publishing Platform this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-01-25 with categories.


What should I do if my symptoms are not relieved while taking Nimodipine medication? How long does the prescription drug Nimodipine stay in your system? How should this Nimodipine medication be stored? Who should NOT take Nimodipine medication? Will Medicare be enough to cover the cost of my medical care, especially Nimodipine prescription drugs? Always talk to your doctor about Nimodipine, your condition and your treatment. But what exactly to ask your doctor to make sure you are both covering everything you need to know about Nimodipine? 'Nimodipine; The Ultimate Step-By-Step Guide' presents readers with a whole new set of 686 pivotal questions to discuss your situation with your healthcare provider, consider your options, and help you make decisions that are right for you. 'Nimodipine; The Ultimate Step-By-Step Guide' poses questions that Nimodipine medication users didn't even know they needed to ask. With lots of room to note down your doctor's answers and an extensive index, this book is a must-have for anyone who has, or is about to have, Nimodipine prescription medication, and indispensable for healthcare providers who want to make sure they are able to answer every question.



Intrathecal Nimodipine Therapy In A Primate Model Of Chronic Cerebral Vasospasm


Intrathecal Nimodipine Therapy In A Primate Model Of Chronic Cerebral Vasospasm
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Author : Paul Jeffrey Lewis
language : en
Publisher:
Release Date : 1987

Intrathecal Nimodipine Therapy In A Primate Model Of Chronic Cerebral Vasospasm written by Paul Jeffrey Lewis and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1987 with Cerebrovascular spasm categories.




Nimodipine


Nimodipine
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Author : Eberhard Betz
language : en
Publisher:
Release Date : 1985

Nimodipine written by Eberhard Betz and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1985 with categories.




The Effect Of Nimodipine On Pulmonary Function In Artificially Ventilated Patients With Aneurysmal Subarachnoid Hemorrhage


 The Effect Of Nimodipine On Pulmonary Function In Artificially Ventilated Patients With Aneurysmal Subarachnoid Hemorrhage
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Author : Justyna Lunkiewicz
language : en
Publisher:
Release Date : 2022

The Effect Of Nimodipine On Pulmonary Function In Artificially Ventilated Patients With Aneurysmal Subarachnoid Hemorrhage written by Justyna Lunkiewicz and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022 with categories.




Safety And Clinical Effects Of Switching From I V To Oral Nimodipine Administration In Aneurysmal Subarachnoid Hemorrhage


Safety And Clinical Effects Of Switching From I V To Oral Nimodipine Administration In Aneurysmal Subarachnoid Hemorrhage
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Author : Julian Christopher Groth
language : en
Publisher:
Release Date : 2022

Safety And Clinical Effects Of Switching From I V To Oral Nimodipine Administration In Aneurysmal Subarachnoid Hemorrhage written by Julian Christopher Groth and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022 with categories.




Development And Validation Of Stability Indicating Method For The Determination Of Nimodipine And Its Possible Degradation Products Using Reverse Phase Liquid Chromatography


Development And Validation Of Stability Indicating Method For The Determination Of Nimodipine And Its Possible Degradation Products Using Reverse Phase Liquid Chromatography
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Author : Hiteshi Solanki
language : en
Publisher:
Release Date : 2018

Development And Validation Of Stability Indicating Method For The Determination Of Nimodipine And Its Possible Degradation Products Using Reverse Phase Liquid Chromatography written by Hiteshi Solanki and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018 with High performance liquid chromatography categories.


"Nimodipine is the latest Calcium channel blocker. It is used for the prevention of major complications of subarachnoid hemorrhage called vasospasm. A simple, linear, accurate, precise, robust reversed-phase HPLC method was developed for the determination of nimodipine raw material on Alltech Krommacil C18 column (250 × 4.6 mm × 5 μm) using mobile phase 50% ACN and 50% Potassium Phosphate Monobasic buffer 25mM at pH 2.5. Total run time was 30 min, flow rate was 1ml/min, injection volume was 10μl and detection wavelength was 237nm. Degradation study was done under different stress conditions: acid hydrolysis, base hydrolysis, oxidation, UV light, heat. The optimum degradation was obtained with 2M HCl, 0.1M NaOH heated for 6hr and 0.5% H2O2 heated for 2hr. Moreover, the developed method was validated as per ICH guidelines for system suitability, specificity, stability, robustness, linearity, accuracy, precision, also for limit of detection and limit of quantitation and this method met all the acceptance criteria."--



Nimodipine And Central Nervous System Function


Nimodipine And Central Nervous System Function
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Author : Jörg Traber
language : en
Publisher:
Release Date : 1989-01-01

Nimodipine And Central Nervous System Function written by Jörg Traber and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1989-01-01 with Calcium categories.