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Nmr In Structural Biology A Collection Of Papers By Kurt Wuthrich


Nmr In Structural Biology A Collection Of Papers By Kurt Wuthrich
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Nmr In Structural Biology A Collection Of Papers By Kurt Wuthrich


Nmr In Structural Biology A Collection Of Papers By Kurt Wuthrich
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Author : Kurt Wuthrich
language : en
Publisher: World Scientific
Release Date : 1995-07-31

Nmr In Structural Biology A Collection Of Papers By Kurt Wuthrich written by Kurt Wuthrich and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995-07-31 with Science categories.


The volume presents a survey of the research by Kurt Wüthrich and his associates during the period 1965 to 1994. A selection of reprints of original papers on the use of NMR spectroscopy in structural biology is supplemented with an introduction, which outlines the foundations and the historical development of the use of NMR spectroscopy for the determination of three-dimensional structures of biological macromolecules in solution. The original papers are presented in groups highlighting protein structure determination by NMR, studies of dynamic properties and hydration of biological macromolecules, and practical applications of the NMR methodology in fields such as enzymology, transcriptional regulation, immunosuppression and protein folding.



Nmr With Biological Macromolecules In Solution


Nmr With Biological Macromolecules In Solution
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Author : Kurt Wüthrich
language : en
Publisher: World Scientific Publishing Company
Release Date : 2021

Nmr With Biological Macromolecules In Solution written by Kurt Wüthrich and has been published by World Scientific Publishing Company this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021 with Science categories.


The book provides insights into the research of the Kurt Wüthrich laboratories from 1996-2020. During this time period, the technique of nuclear magnetic resonance (NMR) spectroscopy in solution went through several breakthroughs, while maturing into a standard method of structural biology. With the introduction of TROSY (transverse relaxation-optimized spectroscopy), the range of accessible molecular sizes was extended about thirty-fold, and efficient protein structure determination resulted from the demands of the structural genomics initiative. Applications in fundamental biology and biomedicine include studies of prion proteins and prion diseases (TSEs), the SARS-Corona virus proteome, trans-membrane signalling by G protein-coupled receptors (GPCRs), and signal transfer by pheromones.Key publications from the Kurt Wüthrich laboratories are placed in perspective, providing insights into new aspects of NMR spectroscopy in structural biology. In addition to methods development, this includes applications in diverse areas of biological research, such as prion proteins and their role in transmissible spongiform encephalopathies (TSEs), trans-membrane signal transfer by G protein-coupled receptors (GPCRs), structural characterization of the SARS-Corona virus proteome, metabolic-flux profiling in bacterial cultures, and signal transfers by pheromones.



Solving Problems With Nmr Spectroscopy


Solving Problems With Nmr Spectroscopy
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Author : Atta-ur Rahman
language : en
Publisher: Academic Press
Release Date : 2015-08-18

Solving Problems With Nmr Spectroscopy written by Atta-ur Rahman and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-08-18 with Science categories.


Solving Problems with NMR Spectroscopy, Second Edition, is a fully updated and revised version of the best-selling book. This new edition still clearly presents the basic principles and applications of NMR spectroscopy with only as much math as is necessary. It shows how to solve chemical structures with NMR by giving many new, clear examples for readers to understand and try, with new solutions provided in the text. It also explains new developments and concepts in NMR spectroscopy, including sensitivity problems (hardware and software solutions) and an extension of the multidimensional coverage to 3D NMR. The book also includes a series of applications showing how NMR is used in real life to solve advanced problems beyond simple small-molecule chemical analysis. This new text enables organic chemistry students to choose the most appropriate NMR techniques to solve specific structures. The problems provided by the authors help readers understand the discussion more clearly and the solution and interpretation of spectra help readers become proficient in the application of important, modern 1D, 2D, and 3D NMR techniques to structural studies. Explains and presents the most important NMR techniques used for structural determinations Offers a unique problem-solving approach for readers to understand how to solve structure problems Uses questions and problems, including discussions of their solutions and interpretations, to help readers understand the fundamentals and applications of NMR Avoids use of extensive mathematical formulas and clearly explains how to implement NMR structure analysis Foreword by Nobel Prize winner Richard R. Ernst New to This Edition Key developments in the field of NMR spectroscopy since the First Edition in 1996 New chapter on sensitivity enhancement, a key driver of development in NMR spectroscopy New concepts such as Pulse Field Gradients, shaped pulses, and DOSY (Diffusion Order Spectroscopy) in relevant chapters More emphasis on practical aspects of NMR spectroscopy, such as the use of Shigemi tubes and various types of cryogenic probes Over 100 new problems and questions addressing the key concepts in NMR spectroscopy Improved figures and diagrams More than 180 example problems to solve, with detailed solutions provided at the end of each chapter



R Ntgen Centennial


R Ntgen Centennial
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Author : A. Haase
language : en
Publisher: World Scientific
Release Date : 1997

R Ntgen Centennial written by A. Haase and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997 with Science categories.


To honour W C R”ntgen and review the entire area of X-ray development in the various fields of natural, technical, and life sciences, his successors at the Physikalisches Institut of the Universit„t Wrzburg organized a conference, named ?R”ntgen Centennial?. It took place at the new ?Physikalisches Institut? not far from the historical site shortly before the actual 100th anniversary of the discovery. Over forty renowned scientists were invited as representative speakers in the various subfields of X-ray activities. They reviewed the development, gave examples, and described the present status. Most of them provided survey articles, which are gathered in this book. Since most X-ray-related activities are somehow represented, an almost complete overview of the entire field is provided. This book thus represents the enormous breadth of X-ray activities and allows one to recognize the potential and quality of today's X-ray research.



Biological Nmr Spectroscopy


Biological Nmr Spectroscopy
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Author : John L. Markley
language : en
Publisher: Oxford University Press
Release Date : 1997-01-30

Biological Nmr Spectroscopy written by John L. Markley and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997-01-30 with Science categories.


This book presents a critical assessment of progress on the use of nuclear magnetic resonance spectroscopy to determine the structure of proteins, including brief reviews of the history of the field along with coverage of current clinical and in vivo applications. The book, in honor of Oleg Jardetsky, one of the pioneers of the field, is edited by two of the most highly respected investigators using NMR, and features contributions by most of the leading workers in the field. It will be valued as a landmark publication that presents the state-of-the-art perspectives regarding one of today's most important technologies.



Determination Of The Structural Factors Contributing To The Bioactivity Of Tgf Beta Analogs


Determination Of The Structural Factors Contributing To The Bioactivity Of Tgf Beta Analogs
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Author : Erika Whitney
language : en
Publisher:
Release Date : 2002

Determination Of The Structural Factors Contributing To The Bioactivity Of Tgf Beta Analogs written by Erika Whitney and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with categories.




Structural Biology


Structural Biology
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Author : Quincy Teng
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-08-02

Structural Biology written by Quincy Teng and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-08-02 with Science categories.


Over the years since NMR was first applied to solve problems in structural biology, it has undergonedramaticdevelopmentsinbothNMRinstrumenthardwareandmethodology. While it is established that NMR is one of the most powerful tools for understanding biological p- cesses at the atomic level, it has become increasingly difficult for authors and instructors to make valid decisions concerning the content and level for a graduate course of NMR in str- turalbiology. BecausemanyofthedetailsinpracticalNMRarenotdocumentedsystematically, students entering the field have to learn the experiments and methods through communication with other experienced students or experts. Often such a learning process is incomplete and unsystematic. This book is meant to be not only a textbook, but also a handbook for those who routinely use NMR to study various biological systems. Thus, the book is organized with experimentalists in mind, whether they are instructors or students. For those who have a little or no background in NMR structural biology, it is hoped that this book will provide sufficient perspective and insight. Those who are already experienced in NMR research may find new information or different methods that are useful to their research. Because understanding fundamental principles and concepts of NMR spectroscopy is essential for the application of NMR methods to research projects, the book begins with an introduction to basic NMR principles. While detailed mathematics and quantum mechanics dealing with NMR theory have been addressed in several well-known NMR books, Chapter 1 illustrates some of the fundamental principles and concepts of NMR spectroscopy in a more descriptiveandstraightforwardmanner.



Books In Print


Books In Print
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Author :
language : en
Publisher:
Release Date : 1991

Books In Print written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1991 with American literature categories.




Chemistry 2001 2005


Chemistry 2001 2005
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Author : Per Ahlberg
language : en
Publisher: World Scientific Publishing Company
Release Date : 2008

Chemistry 2001 2005 written by Per Ahlberg and has been published by World Scientific Publishing Company this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with Biography & Autobiography categories.


A collection of the Nobel Lectures delivered by the prizewinners in chemistry, together with their biographies, portraits and the presentation speeches.



Les Prix Nobel


Les Prix Nobel
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Author :
language : en
Publisher:
Release Date : 2002

Les Prix Nobel written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Nobel Prizes categories.


Vol. for 1901 has a sketch of Alfred Nobel and his works, by P.T. Cleve.