Nonmammalian Genomic Analysis
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Nonmammalian Genomic Analysis
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Author : Bruce Birren
language : en
Publisher: Academic Press
Release Date : 1996-09-25
Nonmammalian Genomic Analysis written by Bruce Birren and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996-09-25 with Science categories.
Offering detailed protocols for those needing to construct a variety of maps and isolate genes, this unique book is intended to popularize the new techniques of genome analysis derived from the Human Genome Project. The power of these new methods is often most striking when applied to problems outside of human genetics, particularly the nonmammalian systems on which many researchers focus. Many of these organisms are economically important and biologically rich. Nonmammalian Genomic Analysis: A Practical Guide covers the "how to" aspects of preparation, handling, cloning, and analysis of large DNA and the creation of chromosome and genome maps. This lab manual facilitates the transfer of these technologies to small "low tech" environments and allows them to be used by those with no background in genome mapping or large-fragment cloning. Like having a local expert, this collection provides procedures for anyone, anywhere, and allows the replication of others' success. Includes detailed and clearly-written step-by-step protocols Evinces expected results and offers trouble shooting advice Provides techniques appropriate for small laboratories as well as those with limited resources Covers a broad variety of cloning systems, including single copy vectors Discusses a diverse range of organisms, from prokaryotes to eukaryotes, from single-celled organisms to highly complex organisms
Toxicogenomics In Non Mammalian Species
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Author : Stephen Sturzenbaum
language : en
Publisher: Frontiers E-books
Release Date :
Toxicogenomics In Non Mammalian Species written by Stephen Sturzenbaum and has been published by Frontiers E-books this book supported file pdf, txt, epub, kindle and other format this book has been release on with categories.
Some molecules or conditions are exclusively toxic to biological systems and classified as being non-essential; others are essential for life. Nevertheless, above certain threshold even the essential will become toxic. Tightly controlled homeostatic control mechanisms are thus vital drivers of well being, longevity and survival. The identification and characterization of these intricate pathways form the foundations of Toxicogenomics. The initiation, and indeed completion, of numerous non-mammalian genome-sequencing projects, has driven the exponential growth of available genetic sequences. Collating this vast amount of data into functional and mechanistically meaningful units will provide novel insights into pathogenesis, new methods of risk assessment, genetic risk-modifications in preventative medicine and new therapeutic targets for pharmaceutical and biological medicines. This Research Topic issue will explore the current knowledgebase pertaining to the multitude of genomic and toxicological tools within non-mammalian organisms. The encyclopaedic coverage will span the full taxonomic breadth ranging from simple unicellular bacteria and yeast to complex creatures such as birds and fish. The resulting collection of unique, complimentary or indeed contrasting approaches, tools and technologies (which are defined by the availability and feasibility for each organism to study genomics of xenobiotic or stress biology) will not only foster cross-phyla awareness but expand the horizon of Toxicogenomics.
Automation Genomic And Functional Analyses
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Author : Alister G. Craig
language : en
Publisher: Elsevier
Release Date : 1999-02
Automation Genomic And Functional Analyses written by Alister G. Craig and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999-02 with Science categories.
Evaluation and functional analysis, to provide insight into this "new age" of research based on genomic and chemical screening. Key Features * Describes automated procedures used in microbiology and molecular biology * Includes developments in robotics and vision systems * Features automation in library picking, presentation and analysis * Discusses paralogous duplications in microbial genomes * Covers deciphering genomes through automated large-scale sequencing * Describes and stresses the need for functional analyses * Internationally acclaimed contributors, including Professor Leroy Hood.
Genome Analysis Analyzing Dna
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Author :
language : en
Publisher:
Release Date : 1997
Genome Analysis Analyzing Dna written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997 with Gene mapping categories.
Reprogramming The Genome Applications Of Crispr Cas In Non Mammalian Systems Part B
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Author :
language : en
Publisher: Academic Press
Release Date : 2021-04-29
Reprogramming The Genome Applications Of Crispr Cas In Non Mammalian Systems Part B written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-04-29 with Science categories.
Reprogramming the Genome: Applications of CRISPR-Cas in Non-mammalian Systems Part B, represents the collation of chapters written by eminent scientists worldwide. CRISPR-Cas9 system is an RNA-mediated immune system of bacteria and archaea that protects from bacteriophage infections. It is one of the revolutionized technologies to uplift biology to the next stages. It is a simple, rapid, precise, and cost-effective tool for genome editing and regulation of a wide range of organisms. It has gained scientific and public attention worldwide. This volume mainly covers insect cell line, protozoans, zebrafish, drosophila, CRISPRi, patents as well as technology transfer, and many more. This book is a key source of information available in a single volume. This book will be useful for not only beginners in genome engineering, but also students, researchers, scientists, policymakers, and stakeholders interested in harnessing the potential of reprogramming of the genomes in several areas. Offers basic understanding and a clear picture of genome editing CRISPR-Cas systems in different organisms Explains how to create an animal model for disease diagnosis/research and reprogram CRISPR for insect cell line, protozoans, zebrafish, drosophila, and many more Discusses the advances, patents, applications, challenges and opportunities in CRISPR-Cas9 systems in basic sciences, biomedicine, molecular biology and many more
Reprogramming The Genome Applications Of Crispr Cas In Non Mammalian Systems Part A
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Author :
language : en
Publisher: Academic Press
Release Date : 2021-03-28
Reprogramming The Genome Applications Of Crispr Cas In Non Mammalian Systems Part A written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-03-28 with Science categories.
Reprogramming the Genome: Applications of CRISPR-Cas in Non-mammalian Systems, Part A presents a collation of chapters written by global, eminent scientists. CRISPR-Cas9 system is an RNA-mediated immune system of bacteria and archaea that protects from bacteriophage infections. It is one of the revolutionized technologies to uplift biology to the next stages. Chapters in this release include An Introduction and applications of CRISPR-Cas Systems, History, evolution and classification of CRISPR-Cas associated systems, CRISPR based bacterial genome editing and removal of pathogens, CRISPR based genome editing and removal of human viruses, CRISPR based development of RNA editing and diagnostic platform, and much more. Additional sections cover Genome engineering in insects for control of vector borne diseases, Development of insect cell line using CRISPR technology, CRISPRing protozoan parasites to better understand the biology of diseases, CRISPR based genome editing of Caenorhabditis elegans, and a variety of other important topics. Offers a basic understanding and clear picture of genome editing CRISPR-Cas systems in different organisms Explains how to create an animal model for disease diagnosis/research and reprogram CRISPR for removal of virus, bacteria, fungi, protozoan, and many more Discusses the advances, patents, applications, challenges and opportunities in CRISPR-Cas9 systems in basic sciences, biomedicine, virology, bacteriology, molecular biology, and many more
The Zebrafish Genetics And Genomics
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Author :
language : en
Publisher: Academic Press
Release Date : 1998-12-03
The Zebrafish Genetics And Genomics written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998-12-03 with Science categories.
This is the second volume of a two-volume, comprehensive treatment of the methodologies used in researching the zebrafish, an emerging vertebrate model system. The text includes discussions on development, genetic methodologies, and model applications. Key Features * Details state-of-the-art zebrafish protocols in a single-source reference * Presents methods and reagents in user-friendly format * Delineates critical steps and pitfalls of he procedures * Illustrates techniques with full-color plates * Summarizes many new and interesting developmental mutants * Includes appendices with strain information and a compendium of zebrafish World Wide Web sites * Relevant to clinicians interested in vertebrate models of human congenital diseases
Autophagy Lower Eukaryotes And Non Mammalian Systems
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Author :
language : en
Publisher: Academic Press
Release Date : 2011-09-02
Autophagy Lower Eukaryotes And Non Mammalian Systems written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-09-02 with Science categories.
This is the companion volume to Daniel Klionsky’s Autophagy: Lower Eukaryotes, which features the basic methods in autophagy covering yeasts and alternative fungi. Klionsky is one of the leading authorities in the field. He is the editor-in-chief of Autophagy. The November 2007 issue of Nature Reviews highlighted his article, “Autophagy: from phenomenology to molecular understanding in less than a decade. He is currently editing guidelines for the field, with 230 contributing authors that will publish in Autophagy. Particularly in times of stress, like starvation and disease, higher organisms have an internal mechanism in their cells for chewing up and recycling parts of themselves. The process of internal “house-cleaning in the cell is called autophagy – literally self-eating. Breakthroughs in understanding the molecular basis of autophagy came after the cloning of ATG1 in yeast. These ATG genes in yeast were the stepping stones to the explosion of research into the molecular analysis of autophagy in higher eukaryotes. In the future, this research will help to design clinical approaches that can turn on autophagy and halt tumor growth. *Establishes the functional roles of specific cellular proteins in selective and nonselective autophagy in mammalian cells, which aides researchers in determining why autophagy is shut down in neoplastia (growth of abnormal tissue mass) and turned on during bacterial invasion *Includes methods to evaluate the role of autophagy in the drug-induced cell death of cancer cells in culture, which helps researchers design clinical approaches that can turn on autophagy and halt tumor growth *Covers higher eukaryotes including lifespan in C.elegans to marine organisms and bridging into the clinical aspects, including autophagy in chronic myelogenous leukemia (CML is one of four types of leukemia), lung cancer, prostate cancer, and cardiac cells.
The Teeth Of Non Mammalian Vertebrates
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Author : Barry Berkovitz
language : en
Publisher: Elsevier
Release Date : 2023-06-17
The Teeth Of Non Mammalian Vertebrates written by Barry Berkovitz and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-06-17 with Science categories.
The Teeth of Non-Mammalian Vertebrates: Form, Function, Development and Growth, Second Edition is devoted to the teeth and dentitions of living fishes, amphibians, and reptiles. This book presents a comprehensive survey of the wide variety of tooth forms among non-mammalian vertebrates, based on descriptions of approximately 450 species belonging to about 170 families.This latest edition discusses the functional morphology of feeding, the attachment of teeth, and the relationship of tooth form to function, with each chapter accompanied by a comprehensive, up-to-date reference list. Following the descriptions of the teeth and dentitions in each class, four chapters review current topics with considerable research activity: tooth development; tooth replacement; and the structure, formation, and evolution of the dental hard tissues. The Teeth of Non-Mammalian Vertebrates: Form, Function, Development and Growth, Second Edition is authored by internationally recognized teachers and researchers in the field. This new edition reflects the resurgence of interest in the dentitions of non-mammalian vertebrates as experimental systems to help understand genetic changes in evolution of teeth and jaws. Features more than 650 images, including photographs from internationally recognized researchers and world class collections Offers in depth information on tooth structure, development, attachment, and replacement Provides detailed descriptions of the dentitions of all living groups of non-mammalian vertebrates Discusses the relationship between tooth form and structure to function in the feeding process
Genetics Manual Current Theory Concepts Terms
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Author : George P Redei
language : en
Publisher: World Scientific
Release Date : 1998-03-31
Genetics Manual Current Theory Concepts Terms written by George P Redei and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998-03-31 with Science categories.
The 1,150 pages contain more information than any other comparable book. It is not a glossary or dictionary or review because all concepts are explained, not just defined or mentioned.Covers the latest developments, usually missed in textbooks and monographs.The broad range of modern genetics, of cell and molecular biology, biometry, etc. are included without glossing over the classical foundations.The hundreds of simple and clear illustrations are vey useful for classroom purposes because they can be drawn on the blackboard or projected on a screen without taking much time to make the crucial points.The cross-references among the entries tie the contents into an extremely useful comprehensive textbook.The concise style leads the reader to the point without verbiage.The etymology of the terms is explained.The text is not intimidating and it is very easy to read because all the terms are explained within the book. Most of the biometrical procedures are presented by worked-out examples in a plain form, rarely or not found at all in other books.It effectively reaches out to non-geneticists without compromising high scientific standards. Usually the most essential features of a concept are presented at the beginning of the entry, and the reader can go as far as she/he feels needed about the logic.The WEB and e-mail addresses of databases and other sources of detailed information are very helpful.A well selected list of about 1000 references, published mainly in the last couple of years, completes the volume.The moderate price makes it a best buy, and an excellent choice to own for students, teachers, scientists, physicians, lawyers and all educated persons who cannot afford an entire library yet wish to be well informed.