Novel Therapies For Combating Bone Diseases Through Advances In Bone Remodeling
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Novel Therapies For Combating Bone Diseases Through Advances In Bone Remodeling
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Author : Chao Liang
language : en
Publisher: Frontiers Media SA
Release Date : 2022-01-17
Novel Therapies For Combating Bone Diseases Through Advances In Bone Remodeling written by Chao Liang and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-17 with Science categories.
Advances In Osteoporosis
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Author : Yannis Dionyssiotis
language : en
Publisher: BoD – Books on Demand
Release Date : 2015-03-04
Advances In Osteoporosis written by Yannis Dionyssiotis and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-03-04 with Medical categories.
A balanced regulation of bone formation and resorption in the healthy individual is required for a healthy bone. On the other side, there are many factors which can lead to alterations in bone density and microarchitecture. Menopause is a condition which can increase the remodeling process in favor of resorption. Moreover, there are also some diseases, i.e. chronic kidney bone disease, that increase the possibility of fractures and the subsequent disability leading to increased mortality. However, it is clear that drugs are an essential element of the therapy and this issue is analyzed extensively in this book. Some novel pathophysiological mechanisms are also presented, offering advanced knowledge to the reader. The book includes chapters from scientific departments and researchers from all over the world.
Bone Health And Osteoporosis
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Author : United States Public Health Service
language : en
Publisher:
Release Date : 2004-12
Bone Health And Osteoporosis written by United States Public Health Service and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-12 with Health & Fitness categories.
This first-ever Surgeon General's Report on bone health and osteoporosis illustrates the large burden that bone disease places on our Nation and its citizens. Like other chronic diseases that disproportionately affect the elderly, the prevalence of bone disease and fractures is projected to increase markedly as the population ages. If these predictions come true, bone disease and fractures will have a tremendous negative impact on the future well-being of Americans. But as this report makes clear, they need not come true: by working together we can change the picture of aging in America. Osteoporosis, fractures, and other chronic diseases no longer should be thought of as an inevitable part of growing old. By focusing on prevention and lifestyle changes, including physical activity and nutrition, as well as early diagnosis and appropriate treatment, Americans can avoid much of the damaging impact of bone disease and other chronic diseases. This Surgeon General's Report brings together for the first time the scientific evidence related to the prevention, assessment, diagnosis, and treatment of bone disease. More importantly, it provides a framework for moving forward. The report will be another effective tool in educating Americans about how they can promote bone health throughout their lives. This first-ever Surgeon General's Report on bone health and osteoporosis provides much needed information on bone health, an often overlooked aspect of physical health. This report follows in the tradition of previous Surgeon Generals' reports by identifying the relevant scientific data, rigorously evaluating and summarizing the evidence, and determining conclusions.
Myeloma Bone Disease
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Author : G. David Roodman
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-04-28
Myeloma Bone Disease written by G. David Roodman and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-04-28 with Medical categories.
This book presents the forefront in the science and clinical management of myeloma bone disease. Coverage begins with sections on clinical presentation, imaging, and biochemical markers and goes on to discuss radiation, surgical, and medical therapies.
Bone Tissue Engineering
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Author : Jeffrey O. Hollinger
language : en
Publisher: CRC Press
Release Date : 2004-10-14
Bone Tissue Engineering written by Jeffrey O. Hollinger and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-10-14 with Medical categories.
Focusing on bone biology, Bone Tissue Engineering integrates basic sciences with tissue engineering. It includes contributions from world-renowned researchers and clinicians who discuss key topics such as different models and approaches to bone tissue engineering, as well as exciting clinical applications for patients. Divided into four sections, t
Hemorrhagic Disorders Advances In Research And Treatment 2011 Edition
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Author :
language : en
Publisher: ScholarlyEditions
Release Date : 2012-01-09
Hemorrhagic Disorders Advances In Research And Treatment 2011 Edition written by and has been published by ScholarlyEditions this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-01-09 with Medical categories.
Hemorrhagic Disorders: Advances in Research and Treatment: 2011 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Hemorrhagic Disorders in a concise format. The editors have built Hemorrhagic Disorders: Advances in Research and Treatment: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Hemorrhagic Disorders in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Hemorrhagic Disorders: Advances in Research and Treatment: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Advanced Techniques In Bone Regeneration
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Author : Alessandro Rozim Zorzi
language : en
Publisher: BoD – Books on Demand
Release Date : 2016-08-31
Advanced Techniques In Bone Regeneration written by Alessandro Rozim Zorzi and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-08-31 with Medical categories.
Advanced Techniques in Bone Regeneration is a book that brings together over 15 chapters, written by leading practitioners and researchers, of the latest advances in the area, including surgical techniques, new discoveries, and promising methods involving biomaterials and tissue engineering. This book is intended for all who work in the treatment of disorders involving problems with the regeneration of bone tissue, are doctors or dentists, as well as are researchers and teachers involved in this exciting field of scientific knowledge.
Glucocorticoid Induced Osteoporosis
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Author : Andrea Giustina
language : en
Publisher: Karger Medical and Scientific Publishers
Release Date : 2002
Glucocorticoid Induced Osteoporosis written by Andrea Giustina and has been published by Karger Medical and Scientific Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Medical categories.
Osteoporosis is one of the most clinically relevant disabling chronic disease encountered in clinical practice. A common cause of osteoporosis is glucocorticoid excess, as glucocorticoids may increase bone resorption, inhibit bone formation, have indirect actions on bone by decreasing intestinal calcium absorption and induce hypercalciuria. This book presents a comprehensive overview of the effects of glucocorticoids on bone metabolism and structure and on the diagnosis and treatment of glucocorticoid-induced osteoporosis. It aims at providing updated information on the pathogenesis, diagnosis and treatment of this often dramatic complication of glucocorticoid excess. Being one of the few publications completely devoted to glucocorticoid-induced osteoporosis it will heighten the awareness of specialists who prescribe glucocorticoids of the clinical relevance of this treatment complication. 'Glucocorticoid-Induced Osteoporosis' is addressed to clinical experts as well as to general practitioners who will both benefit from the comprehensive and integrative view of the management of patients exposed to glucocorticoids.
Advances In Biology And Therapy Of Multiple Myeloma
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Author : Nikhil C. Munshi
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-09
Advances In Biology And Therapy Of Multiple Myeloma written by Nikhil C. Munshi and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-09 with Medical categories.
Despite the advances in conventional, novel agent and high dose chemotherapy multiple myeloma (MM) remains incurable. In order to overcome resistance to current therapies and improve patient outcome, novel biologically-based treatment approaches are being developed. Current translational research in MM focusing on the development of molecularly-based combination therapies has great promise to achieve high frequency and durable responses in the majority of patients. Two major advances are making this goal possible. First, recent advances in genomics and proteomics in MM have allowed for increased understanding of disease pathogenesis, identified novel therapeutic targets, allowed for molecular classification, and provided the scientific rationale for combining targeted therapies to increase tumor cell cytotoxicity and abrogate drug resistance. Second, there is now an increased understanding of how adhesion of MM cells in bone marrow (BM) further impacts gene expression in MM cells, as well as in BM stromal cells (BMSCs). As a result of these advances in oncogenomics on the one hand and increased understanding of the role of the BM in the pathogenesis of MM on the other, a new treatment paradigm targeting the tumor cell and its BM microenvironment to overcome drug resistance and improve patient outcome has now been developed. Thalidomide, lenalidomide, and Bortezomib are three agents which target the tumor cell in its microenvironment in both laboratory and animal models and which have rapidly translated from the bench to the bedside. Ongoing efforts are using oncogenomics and cell signaling studies to identify next generation of therapies in MM on the one hand, and to inform the design of combination trials on the other. This new paradigm for overcoming drug resistance and improving patient outcome in MM has great promise not only to change the natural history of MM, but also to serve as a model for targeted therapeutics directed to improve outcome of patients with MM.
Pocket Reference To Osteoporosis
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Author : Serge Livio Ferrari
language : en
Publisher: Springer
Release Date : 2018-12-28
Pocket Reference To Osteoporosis written by Serge Livio Ferrari and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-12-28 with Medical categories.
This book responds to the daily needs of all clinicians treating patients with osteoporosis and provides a key reference guide for any challenges that arise in clinical practice. This book also covers the genetics of the disease, clinical presentation, diagnosis, and current and upcoming treatment recommendations in accordance with the latest international guidelines. Osteoporosis is a disease in which the density and quality of bone are greatly reduced, and as bones become more porous and fragile the risk of fracture increases greatly. It is one of the most common metabolic bone diseases globally with one in three women and one in five men at risk of an osteoporotic fracture, and can result in devastating physical, psychosocial, and economic consequences. However, in spite of this osteoporosis can often be overlooked and undertreated, thus there is a real need to raise awareness of this disease.