Novel Vaccination Strategies
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Novel Vaccination Strategies
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Author : Stefan H. E. Kaufmann
language : en
Publisher: John Wiley & Sons
Release Date : 2006-01-24
Novel Vaccination Strategies written by Stefan H. E. Kaufmann and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-01-24 with Science categories.
The protection mode of most available vaccines is based on antibody responses. Since efficient immune responses to many pathogens rely on activating all arms of the immune system, traditional vaccine development does not provide efficient protection against many diseases. Novel vaccination strategies need to allow presentation of antigens that activate the full array of the immune response in the right composition and should prevent pathogen entry by mobilizing the mucosal immune response. New technological advances optimize the immunogenicity of 'live' and sub-unit vaccines. This book offers an interdisciplinary overview on research and future strategies for rational vaccine design based on recent developments in molecular biology and immunology. It covers new aspects of the immunological interplay between prokaryotic and eukaryotic systems as well as achievements in the development of novel vaccine candidates. Chapters on edible vaccines, on vaccines against bioterror agents and on economical and safety aspects of novel vaccine development round off this title.
Vaccination Strategies Against Highly Variable Pathogens
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Author : Lars Hangartner
language : en
Publisher: Springer Nature
Release Date : 2020-09-01
Vaccination Strategies Against Highly Variable Pathogens written by Lars Hangartner and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-09-01 with Medical categories.
Vaccines against antigenically stable pathogens, or pathogens that only exist in a limited number of serotypes, have been very successful in the past and have drastically decreased the incidence and lethality of many diseases. However, when it comes to highly variable pathogens or viruses that exist in multiple serotypes, the traditional methods for vaccine development have reached their limits. This volume highlights the development of vaccines against such challenging pathogens. Novel approaches for immunogen design, including structure-guided vaccine development and vaccines targeting glycans, as well as adjuvants and animal models used for testing possible vaccine candidates are outlined and discussed in detail. Given its scope, the book will appeal to scientists in the fields of infectious diseases, microbiology and medicine.
Novel Strategies In The Design And Production Of Vaccines
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Author : Sara Cohen
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-06-29
Novel Strategies In The Design And Production Of Vaccines written by Sara Cohen and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-29 with Medical categories.
Vaccination is one of the most efficient and cost effective methods of promoting human health and has been in clinical use for at least 200 years. Nevertheless, infectious diseases continue to constitute a constant threat to the well being of humanity. Common pathogens, once believed to be under control, acquire increased virulence and resistance to drugs, while exotic microorganisms emerged from hidden reservoirs to cause yet incurable diseases in humans. These changes, together with epidemic outbreaks related to political and socio-economic instabilities, increase the needs for the development of new, advanced vaccines. In this volume, devoted to the proceedings of the 39th OHOLO Conference, we present some of the recent strategies for the design and production of novel vaccines. The advent of recombinant DNA technology has stimulated the production of several subunit vaccines. In spite of the obvious advantages to this approach, the limited immuno genicity of many subunit candidates has hindered their development. Strategies to enhance the immunogenicity of subunit vaccines is therefore critical. Several approaches toward this goal, including design of novel adjuvants and delivery systems as well as design of advantageous carriers, are presented here. Among the carriers evaluated here are polypep tides (flagellin, HBV core antigen, J3-galactosidase), attenuated virions (Vaccinia, Sindbis), and nonpathogenic licensed bacteria (Salmonella).
Novel Vaccination Strategies For Induction Of Long Term Immune Memory And Protection Of Bovine Respiratory Disease
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Author : Saskatchewan. Agriculture Development Fund
language : en
Publisher:
Release Date : 2011
Novel Vaccination Strategies For Induction Of Long Term Immune Memory And Protection Of Bovine Respiratory Disease written by Saskatchewan. Agriculture Development Fund and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011 with Vaccination of animals categories.
New Vaccination Strategies Based On Novel Adjuvants And Delivery Systems
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Author : Pablo Daniel Becker
language : en
Publisher:
Release Date : 2007
New Vaccination Strategies Based On Novel Adjuvants And Delivery Systems written by Pablo Daniel Becker and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with categories.
Novel Vaccination Strategies For Cd4 T Cell Immunotherapy Of Melanoma
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Author : Naveen Shridhar
language : en
Publisher:
Release Date : 2019
Novel Vaccination Strategies For Cd4 T Cell Immunotherapy Of Melanoma written by Naveen Shridhar and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019 with categories.
Microarray Anwendungen In Grundlagenforschung Und Routinebetrieb
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Author : DECHEMA, Gesellschaft für Chemische Technik und Biotechnologie
language : en
Publisher:
Release Date : 2007
Microarray Anwendungen In Grundlagenforschung Und Routinebetrieb written by DECHEMA, Gesellschaft für Chemische Technik und Biotechnologie and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with categories.
Novel Technologies For Vaccine Development
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Author : Igor S Lukashevich
language : en
Publisher: Springer
Release Date : 2014-11-13
Novel Technologies For Vaccine Development written by Igor S Lukashevich and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-11-13 with Medical categories.
This book presents a detailed overview of the development of new viral vector-based vaccines before discussing two major applications: preventive vaccines for infectious diseases and therapeutic cancer vaccines. Viral vector-based vaccines hold a great potential for development into successful pharmaceutical products and several examples at the advanced pre-clinical or clinical stage are presented. Nevertheless, the most efforts were focused on novel and very innovative technologies for new generation of vector-based vaccines. Furthermore, specific topics such as delivery and adjuvant and protection strategies for cell-mediated-based vaccines are presented. Given its scope, the book is a “must read” for all those involved in vaccine development, both in academia and industrial vaccine development.
New Generation Vaccines And Novel Vaccinal Strategies Against Infectious Diseases Of Livestock Wild And Companion Animals
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Author : Denis Archambault
language : en
Publisher: Frontiers Media SA
Release Date : 2023-08-25
New Generation Vaccines And Novel Vaccinal Strategies Against Infectious Diseases Of Livestock Wild And Companion Animals written by Denis Archambault and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-08-25 with Medical categories.
Emerging and re-emerging infections, in particular those caused by viruses, are expected to rise in correlation, among other factors, with climate changes. Antibiotic resistance is another issue that will limit the therapeutic arsenal against bacterial and parasitic infections. Therefore, one must be adequately prepared to overcome and prevent current and novel infections, and vaccination remains the optimal way to fight infectious diseases in humans. This is also true for many impacting diseases of livestock and companion animals, to which there are no available vaccines. First (attenuated and inactivated) and second (subunit) generation vaccines have their limitations. To overcome this, efforts have been made in recent years to develop novel vaccine types such as virus-like particle (VLP)-, viral vector-, and DNA-based vaccines in humans and animals. The recent success in utilizing RNA technology based-vaccines to fight SARS-CoV-2 to limit the severity of clinical symptoms and mortality constitutes a promising way to develop such vaccines against animal diseases. Development of novel molecules or materials with adjuvant or immunostimulatory activity to adequately stimulate the innate immune response, and, therefore the pathogen-specific adaptative immune response, as well as the identification of suitable antigenic material that would bring broad protection against infectious agent variants are other key issues to be considered in developing safe and innovative immunization strategies.
The Vaccine Book
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Author : Barry R. Bloom
language : en
Publisher: Academic Press
Release Date : 2016-06-23
The Vaccine Book written by Barry R. Bloom and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-06-23 with Medical categories.
The Vaccine Book, Second Edition provides comprehensive information on the current and future state of vaccines. It reveals the scientific opportunities and potential impact of vaccines, including economic and ethical challenges, problems encountered when producing vaccines, how clinical vaccine trials are designed, and how to introduce vaccines into widespread use. Although vaccines are now available for many diseases, there are still challenges ahead for major diseases, such as AIDS, tuberculosis, and malaria. This book is designed for students, researchers, public health officials, and all others interested in increasing their understanding of vaccines. It answers common questions regarding the use of vaccines in the context of a rapidly expanding anti-vaccine environment. This new edition is completely updated and revised with new and unique topics, including new vaccines, problems of declining immunization rates, trust in vaccines, the vaccine hesitancy, and the social value of vaccines for the community vs. the individual child’s risk. Provides insights into diseases that could be prevented, along with the challenges facing research scientists in the world of vaccines Gives new ideas about future vaccines and concepts Introduces new vaccines and concepts Gives ideas about challenges facing public and private industrial investors in the vaccine area Discusses the problem of declining immunization rates and vaccine hesitancy