O Glcnacylation Expanding The Frontiers
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O Glcnacylation Expanding The Frontiers
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Author : Tarik Issad
language : en
Publisher: Frontiers Media SA
Release Date : 2020-01-23
O Glcnacylation Expanding The Frontiers written by Tarik Issad and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-01-23 with categories.
Insights In Aging Metabolism And Redox Biology 2021 2022
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Author : Jianhua Zhang
language : en
Publisher: Frontiers Media SA
Release Date : 2024-07-08
Insights In Aging Metabolism And Redox Biology 2021 2022 written by Jianhua Zhang and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-07-08 with Science categories.
We are now in the third decade of the 21st Century and, especially in recent years, the achievements made by scientists have been exceptional, leading to major advancements in the fast-growing field of Aging, Metabolism, and Redox Biology. This editorial initiative of particular relevance is focused on new insights, novel developments, current challenges, latest discoveries, recent advances, and future perspectives in the field of Aging, Metabolism, and Redox Biology.
Innovators In Chemical Biology
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Author : John D. Wade
language : en
Publisher: Frontiers Media SA
Release Date : 2022-11-10
Innovators In Chemical Biology written by John D. Wade and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-11-10 with Science categories.
30 Years Old O Glcnac Reaches Age Of Reason Regulation Of Cell Signaling And Metabolism By O Glcnacylation
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Author : Tony Lefebvre
language : en
Publisher: Frontiers Media SA
Release Date : 2015-06-10
30 Years Old O Glcnac Reaches Age Of Reason Regulation Of Cell Signaling And Metabolism By O Glcnacylation written by Tony Lefebvre and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-06-10 with Diseases of the endocrine glands. Clinical endocrinology categories.
Hundreds post-translational modifications (PTM) were characterized among which a large variety of glycosylations including O-GlcNAcylation. Since its discovery, O-GlcNAcylation has emerged as an unavoidable PTM widespread in the living beings including animal and plant cells, protists, bacteria and viruses. In opposition to N- and O-glycosylations, O-GlcNAcylation only consists in the transfer of a single N-acetylglucosamine moiety through a beta-linkage onto serine and threonine residues of proteins confined within the cytosol, the nucleus and the mitochondria. The O-GlcNAc group is provided by UDP-GlcNAc, the end-product of the hexosamine biosynthetic pathway located at the crossroad of cell metabolisms making O-GlcNAcylation a PTM which level tightly reflects nutritional status; therefore regulation of cell homeostasis should be intimately correlated to lifestyle and environment. Like phosphorylation, with which it can compete, O-GlcNAcylation is reversible. This versatility is managed by OGT (O-GlcNAc transferase) that transfers the GlcNAc group and OGA (O-GlcNAcase) that removes it. Also, like its unsweetened counterpart, O-GlcNAcylation controls fundamental processes, e.g. protein fate, chromatin topology, DNA demethylation and, as recently revealed, circadian clock. Deregulation of O-GlcNAc dynamism may be involved in the emergence of cancers, neuronal and metabolic disorders such as Alzheimer's or diabetes respectively. This Research Topic in Frontiers in Endocrinology is the opportunity to celebrate the thirtieth anniversary of the discovery of "O-GlcNAc" by Gerald W. Hart.
Essentials Of Glycobiology
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Author : Ajit Varki
language : en
Publisher: CSHL Press
Release Date : 1999
Essentials Of Glycobiology written by Ajit Varki and has been published by CSHL Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999 with Medical categories.
Sugar chains (glycans) are often attached to proteins and lipids and have multiple roles in the organization and function of all organisms. "Essentials of Glycobiology" describes their biogenesis and function and offers a useful gateway to the understanding of glycans.
Epigenetic Mechanisms And Their Involvement In Rare Diseases
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Author : Mojgan Rastegar
language : en
Publisher: Frontiers Media SA
Release Date : 2021-10-20
Epigenetic Mechanisms And Their Involvement In Rare Diseases written by Mojgan Rastegar and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-10-20 with Science categories.
Drug Resistance In Cancer Cells A New Wine In An Old Bottle
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Author : Leonardo Freire-de-Lima
language : en
Publisher: Frontiers Media SA
Release Date : 2023-04-05
Drug Resistance In Cancer Cells A New Wine In An Old Bottle written by Leonardo Freire-de-Lima and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-04-05 with Medical categories.
Frontiers In Aging Neuroscience Editor S Pick 2021
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Author : Thomas Wisniewski
language : en
Publisher: Frontiers Media SA
Release Date : 2021-08-03
Frontiers In Aging Neuroscience Editor S Pick 2021 written by Thomas Wisniewski and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-08-03 with Science categories.
Marine Environmental Epigenetics
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Author : Jose M. Eirin-Lopez
language : en
Publisher: Frontiers Media SA
Release Date : 2021-07-05
Marine Environmental Epigenetics written by Jose M. Eirin-Lopez and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-07-05 with Science categories.
Transforming Glycoscience
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Author : National Research Council
language : en
Publisher: National Academies Press
Release Date : 2012-10-23
Transforming Glycoscience written by National Research Council and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-10-23 with Science categories.
A new focus on glycoscience, a field that explores the structures and functions of sugars, promises great advances in areas as diverse as medicine, energy generation, and materials science, this report finds. Glycans-also known as carbohydrates, saccharides, or simply as sugars-play central roles in many biological processes and have properties useful in an array of applications. However, glycans have received little attention from the research community due to a lack of tools to probe their often complex structures and properties. Transforming Glycoscience: A Roadmap for the Future presents a roadmap for transforming glycoscience from a field dominated by specialists to a widely studied and integrated discipline, which could lead to a more complete understanding of glycans and help solve key challenges in diverse fields.