Oncogenes And Cancer
DOWNLOAD
Download Oncogenes And Cancer PDF/ePub or read online books in Mobi eBooks. Click Download or Read Online button to get Oncogenes And Cancer book now. This website allows unlimited access to, at the time of writing, more than 1.5 million titles, including hundreds of thousands of titles in various foreign languages. If the content not found or just blank you must refresh this page
Oncogenes
DOWNLOAD
Author : Kathy B. Burck
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Oncogenes written by Kathy B. Burck and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
"Cancer viruses" have played a paradoxical role in the history of cancer research. Discovered in 1911 by Peyton Rous (1) at the Rockefeller Institute, they were largely ignored for several decades. Witness his eventual recognition for a Nobel Prize, but not until 1966-setting an all time record for latency, and testimony to one more advantage of longevity. In the 1950s, another Rockefeller Nobelist, Wendell Stanley, spearheaded a campaign to focus attention on viruses as etiological agents in cancer, his plat form having been the chemical characterization of the tobacco mosaic virus as a pure protein-correction, ribonucleoprotein-in 1935 (2). This doctrine was a centerpiece of the U.S. National Cancer Crusade of 1971: if human cancers were caused by viruses, the central task was to isolate them and prepare vaccines for immunization. At that point, many observers felt that perhaps too much attention was being devoted to cancer viruses. It was problematic whether viruses played an etiological role in more than a handful of human cancers.
Oncogenes And Tumor Suppressor Genes In Human Malignancies
DOWNLOAD
Author : Christopher Benz
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Oncogenes And Tumor Suppressor Genes In Human Malignancies written by Christopher Benz and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
The first edition of Oncogenes (1989) focused on several of the better known transforming mechanisms and surveyed a spectrum of solid tumors and hematologic malignancies. Several of the nearly 50 known oncogenes most relevant to human disease were examined. In contrast, this volume presents a very different profile and balance of subject material that reflects the rapidly changing field of molecular oncology and its newly emerging concepts. Among the most important discoveries of the past 4 years are the identification of nearly a dozen different tumor suppressor genes and the finding of an entirely new class of cancer-causing gene (bcl-2) that acts by inhibiting cell death rather than stimulating cell proliferation. This edition begins by reviewing selected malignancies in which our earlier search for clinically relevant oncogenes has led to more focused studies on gain-of-function and loss-of-function genetic abnormalities, as well as autocrine and paracrine growth factor loops known to regulate tumor physiology and malignant cell behavior. Curiously, many of these genetic and functional abnormalities are shared by several different tumor types and are not uniformly present in all tumors of the same type. This observation brings up molecular questions about the tissue-specific determinants that underlie individual cancers and also gives added impetus to the suggestion that molecular abnormalities (referred to as tumor markers) be included among the histopathologic features used for clinical diagnosis and manage ment.
Oncogene And Cancer
DOWNLOAD
Author : Yahwardiah Siregar
language : en
Publisher: Inst za onkologiju i radiol
Release Date : 2013-01-24
Oncogene And Cancer written by Yahwardiah Siregar and has been published by Inst za onkologiju i radiol this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-01-24 with Medical categories.
This book describes a course of cancer growth starting from normal cells to cancerous form and the genomic instability, the cancer treatment as well as its prevention in form of the invention of a vaccine. Some diseases are also discussed in detail, such as breast cancer, leucaemia, cervical cancer, and glioma. Understanding cancer through its molecular mechanism is needed to reduce the cancer incidence. How to treat cancer more effectively and the problems like drug resistance and metastasis are very clearly illustrated in this publication as well as some research result that could be used to treat the cancer patients in the very near future. The book was divided into six main sections: 1. HER2 Carcinogenesis: Etiology, Treatment and Prevention; 2. DNA Repair Mechanism and Cancer; 3. New Approach to Cancer Mechanism; 4. New Role of Oncogenes and Tumor Suppressor Genes; 5. Non Coding RNA and Micro RNA in Tumorigenesis; 6. Oncogenes for Transcription Factors
Oncogenes And Carcinogenesis
DOWNLOAD
Author : Pinar Erkekoglu
language : en
Publisher: BoD – Books on Demand
Release Date : 2019-03-06
Oncogenes And Carcinogenesis written by Pinar Erkekoglu and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-03-06 with Medical categories.
Oncogenes are mutated and/or overexpressed at high levels in tumor cells. Tumors of the lung, breast, pancreas, and colon may display specific oncogenetic features. These tumors have been largely associated with exposure to environmental carcinogens and a variety of biological agents, including viruses. These carcinogens can induce specific genetic and epigenetic alterations in these tissues, leading to aberrant functioning of oncogenes and tumor suppressor genes. On the microRNAs (miRNAs) there are significant modifiers of both transcription and translation of oncogenes in carcinogenesis. In the last 50 years, several oncogenes and microRNAs related to these oncogenes have been identified in different types of human cancers. It is now clear that high expression of oncogenes, DNA damage response, and regulation of the cell cycle are related to the circadian clock. This book will mainly focus on the expressions of different oncogenes in breast, colon, and lung cancers. Moreover, readers will gain qualified scientific knowledge of the alterations in miRNAs in different types of cancers and the effects of the circadian clock on the expression of oncogenes in carcinogenesis.
Holland Frei Cancer Medicine
DOWNLOAD
Author : Robert C. Bast, Jr.
language : en
Publisher: John Wiley & Sons
Release Date : 2017-03-10
Holland Frei Cancer Medicine written by Robert C. Bast, Jr. and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-03-10 with Medical categories.
Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates
Introduction To Oncogenes And Molecular Cancer Medicine
DOWNLOAD
Author : Dennis W. Ross
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Introduction To Oncogenes And Molecular Cancer Medicine written by Dennis W. Ross and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Providing the physician with a solid understanding of molecular biology and its applications for the diagnosis and treatment of cancer, this book reviews the basic molecular and other principles of cancer medicine, including controls of cell growth and senescence, carcinogenesis, tumorogenesis, and epidemiology. The second part of the book gives clinical examples to demonstrate the basic science principles, including chapters on leukaemia, colon cancer, and breast cancer. A chapter on molecular diagnostics and screening plus a chapter on new molecular anti-cancer therapies allow readers an insight into current therapies as well as the future of molecular cancer medicine. A useful glossary defines new terminology at-a-glance. Written in a user-friendly, conversational format, this text will be welcomed by all physicians eager to sharpen their own understanding of molecular cancer medicine as well as to help them provide patients with balanced information on the advances and limitations of current treatment options.
Oncogenes In Cancer Diagnosis
DOWNLOAD
Author : C. R. Bartram
language : en
Publisher: S. Karger AG (Switzerland)
Release Date : 1990
Oncogenes In Cancer Diagnosis written by C. R. Bartram and has been published by S. Karger AG (Switzerland) this book supported file pdf, txt, epub, kindle and other format this book has been release on 1990 with Cancer categories.
Oncogene Directed Therapies
DOWNLOAD
Author : Janusz W. Rak
language : en
Publisher: Springer Science & Business Media
Release Date : 2002-12-03
Oncogene Directed Therapies written by Janusz W. Rak and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002-12-03 with Medical categories.
Prominent investigators and clinicians summarize in a balanced blend of fundamental science, basic research, experimental therapeutics, and early clinical experiences, what is known about oncogenes and oncogenesis, and describe how that knowledge can be used to treat the cancer. The contributors explain how, why, and under what conditions certain proteins acquire the ability to transform eukaryotic cells, and detail the crucial biological consequences of this oncogenic transformation, particularly for cellular mitogenesis, survival, differentiation, migration, proteolysis, or angiogenic competence. Their articles thoroughly explicate the premises, principles, techniques, and approaches to oncogene targeting in various types of human cancer by using signal transduction inhibitors, immunological targeting methods, and antisense gene therapy.
Oncogene And Cancer
DOWNLOAD
Author : Eden Dennis
language : en
Publisher:
Release Date : 2015-03-17
Oncogene And Cancer written by Eden Dennis and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-03-17 with Cancer categories.
The course of cancer development has been presented in this book beginning from normal cells to cancerous form and the genomic instability, the cancer treatment as well as its prevention in the form of the invention of a vaccine. Certain diseases are also elucidated, like leukaemia, glioma, breast cancer, and cervical cancer. Comprehending cancer through its molecular mechanism is required to decrease the cancer incidence. Complications like metastasis and drug resistance and the procedure of treating cancer more efficiently are vividly illuminated in this book along with some research results that could be employed to treat the cancer patients in the not too distant future. The book encompasses topics like HER2 carcinogenesis: treatment, etiology & prevention; DNA repair mechanism & cancer; new approach to cancer mechanism and novel role of oncogenes & tumor suppressor genes.
Oncogene And Cancer
DOWNLOAD
Author : Yahwardiah Siregar
language : en
Publisher:
Release Date : 2013
Oncogene And Cancer written by Yahwardiah Siregar and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013 with categories.
This book describes a course of cancer growth starting from normal cells to cancerous form and the genomic instability, the cancer treatment as well as its prevention in form of the invention of a vaccine. Some diseases are also discussed in detail, such as breast cancer, leucaemia, cervical cancer, and glioma. Understanding cancer through its molecular mechanism is needed to reduce the cancer incidence. How to treat cancer more effectively and the problems like drug resistance and metastasis are very clearly illustrated in this publication as well as some research result that could be used to treat the cancer patients in the very near future. The book was divided into six main sections: 1. HER2 Carcinogenesis: Etiology, Treatment and Prevention; 2. DNA Repair Mechanism and Cancer; 3. New Approach to Cancer Mechanism; 4. New Role of Oncogenes and Tumor Suppressor Genes; 5. Non Coding RNA and Micro RNA in Tumorigenesis; 6. Oncogenes for Transcription Factors.