Opioid Peptides In Substance Abuse
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Opioid Peptides In Substance Abuse
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Author : Joseph I. Szekely
language : en
Publisher: CRC Press
Release Date : 1993-10-22
Opioid Peptides In Substance Abuse written by Joseph I. Szekely and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993-10-22 with Medical categories.
Opioid Peptides in Substance Abuse presents an encyclopedic survey of in vivo data examining the interrelationship between endogenous opioids and substance abuse. It emphasizes two main groups of abused substances (morphine congeners and psychostimulants) and addresses the following questions:
Pharmacology Of Opioid Peptides
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Author : L F Tseong
language : en
Publisher: CRC Press
Release Date : 1995-09-01
Pharmacology Of Opioid Peptides written by L F Tseong and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995-09-01 with Medical categories.
This book is being published at a time when opioid receptors have recently been cloned. The structural characteristics of opioid receptors and the recent advances in their molecular cloning and expression are explicated. Connecting these cloned opioid receptors with the pharmacology of opioid receptor actions is of particular importance. The use of antisense oligodeoxynucleotides to opioid receptors to elucidate the neural mechanisms of opioid action is detailed. As analgesia is one of the most important clinical functions for opioids and opioid peptides, this book concentrates on the detailed mechanisms of action of opioids and opioid peptides for the production of analgesia. The significant pharmacologic actions of opioids and opioid peptides in gastrointestinal function, immune function, cardiovascular and respiratory regulation, addiction and the cellular mechanisms involved in tolerance and dependence of opioids are also described. The book will be of interest both to researchers investigating the neural mechanisms of the pharmacologic and physiologic functions of the endogenous opioid system and to clinicians who are involved in pain management and assessment.
Opioid Peptides
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Author : Rao S. Rapaka
language : en
Publisher:
Release Date : 1986
Opioid Peptides written by Rao S. Rapaka and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1986 with Endorphins categories.
"This monograph is based upon papers and discussion from the technical review on the medicinal chemistry and molecular pharmacology of opioid peptides and the opiates which took place on September 4-6, 1984, at Bethesda, Maryland. The meeting was sponsored by the Office of Science and the Division of Preclinical Research, National Institute on Drug Abuse. The papers on molecular pharmacology, biosynthesis, and analysis of opioid peptides are presented in this volume. Those on the medical chemistry of opioid peptides appear in NIDA Research Monograph 69" [entitled Opioid peptides : medicinal chemistry] -- page iv.
Opioid Peptides
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Author : National Institute on Drug Abuse
language : en
Publisher:
Release Date : 1988
Opioid Peptides written by National Institute on Drug Abuse and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1988 with Clinical chemistry categories.
Discovery Of Novel Opioid Medications
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Author :
language : en
Publisher:
Release Date : 1995
Discovery Of Novel Opioid Medications written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995 with Drug addiction categories.
Endogenous Opioid Peptides In Drug Addiction
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Author : Britta Schürmann
language : en
Publisher:
Release Date : 2009
Endogenous Opioid Peptides In Drug Addiction written by Britta Schürmann and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009 with categories.
Molecular And Cellular Aspects Of The Drug Addictions
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Author : Avram Goldstein
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Molecular And Cellular Aspects Of The Drug Addictions written by Avram Goldstein and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
In 1970 I gave up the chairmanship of the Department of Pharmacology at Stanford University Schoel of Medicine to devote full time to basic and clinical research on problems of drug addiction. In 1971 I developed the method of radioligand binding that led to the important characterization of opioid receptors in several laboratories. The extraordinary specificity of these receptors for morphine and related opiates suggested the likelihood that there were naturally occurring morphine-like molecules in the brain and other tissues. The systematic search for these molecules culminated in 1979 in the discovery, by my group, ofthe dynorphin peptides-one of the three families of opioid peptides, the first of which (the enkephalin family) had been discovered in Aberdeen, Scotland, in 1975. I also became involved in clinical research on the pharmacologic treatment of heroin addicts, for which I established the first large methadone mainte nance treatment program in California. My basic and clinical research experience convinced me that an institution encompassing laboratory research, studies on normal human volunteers, and treatment research, under a single roof, could expedite progress in understanding the drug addictions. That concept was transformed into reality by the founding, in 1974, of the Addiction Research Foundation of Palo Alto, California. The funds for construction of a laboratory were provided by a generous grant from the Drug Abuse Council (a consortium of several foundations), the president of which was Thomas L. Bryant.
Opioid Peptides
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Author : Rao S. Rapaka
language : en
Publisher:
Release Date : 1986
Opioid Peptides written by Rao S. Rapaka and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1986 with Analgesics categories.
Opiate Receptors Neurotransmitters And Drug Dependence
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Author : Barry Stimmel
language : en
Publisher: Routledge
Release Date : 2014-06-03
Opiate Receptors Neurotransmitters And Drug Dependence written by Barry Stimmel and has been published by Routledge this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-06-03 with Psychology categories.
Experts address the role of neuromodulators and opiate receptors in alcohol and drug dependence. They present innovative research techniques, new discoveries, and possible clinical correlates that allow for a much greater understanding of the clinical phenomena surrounding alcohol and narcotic use. Included in this thought-provoking volume are a comprehensive review of the current knowledge of the endogenous opiates, their interactions with the opiate receptors, and the potential relationship that these substances might have in promoting the development of dependence, tolerance, and withdrawal; the translation of the basic physiologic findings occuring during withdrawal to treatment of withdrawal symptoms in the clinical setting; and a physiological explanation for the rationale of using clonidine and naltrexone to accelaerate the detoxification process without undue discomfort.
Molecular Approaches To Drug Abuse Research Structure Function And Expression
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Author :
language : en
Publisher:
Release Date : 1991
Molecular Approaches To Drug Abuse Research Structure Function And Expression written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1991 with Drug abuse categories.