Optimisation Of Illicit Drug Detection Using X Ray Diffraction
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Optimisation Of Illicit Drug Detection Using X Ray Diffraction
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Author : Ireneos Drakos
language : en
Publisher:
Release Date : 2015
Optimisation Of Illicit Drug Detection Using X Ray Diffraction written by Ireneos Drakos and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015 with categories.
Optimisation Of Illicit Drug Detection Using X Ray Diffraction
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Author : I. Drakos
language : en
Publisher:
Release Date : 2015
Optimisation Of Illicit Drug Detection Using X Ray Diffraction written by I. Drakos and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015 with categories.
Optimization Of An X Ray Diffraction Imaging System For Medical And Security Applications
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Author : Fanny Marticke
language : en
Publisher:
Release Date : 2016
Optimization Of An X Ray Diffraction Imaging System For Medical And Security Applications written by Fanny Marticke and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016 with categories.
X-ray diffraction imaging is a powerful noninvasive technique to identify or characterize different materials. Compared to traditional techniques using X-ray transmission, it allows to extract more material characteristic information, such as the Bragg peak positions for crystalline materials as well as the molecular form factor for amorphous materials. The potential of this technique has been recognized by many researchers and numerous applications such as luggage inspection, nondestructive testing, drug detection and biological tissue characterization have been proposed.The method of energy dispersive X-ray diffraction (EDXRD) is particularly suited for this type of applications as it allows the use of a conventional X-ray tube, the acquisition of the whole spectrum at the same time and parallelized architectures to inspect an entire object in a reasonable time. The purpose of the present work is to optimize the whole material characterization chain. Optimization comprises two aspects: optimization of the acquisition system and of data processing. The last one concerns especially the correction of diffraction pattern degraded by acquisition process. Reconstruction methods are proposed and validated on simulated and experimental spectra. System optimization is realized using figures of merit such as detective quantum efficiency (DQE), contrast to noise ratio (CNR) and receiver operating characteristic (ROC) curves.The first chosen application is XRD based breast imaging which aims to distinguish cancerous tissues from healthy tissues. Two non-multiplexed collimation configurations combining EDXRD and ADXRD are proposed after optimization procedure. A simulation study of the whole system and a breast phantom was realized to determine the required dose to detect a 4 mm carcinoma nodule. The second application concerns detection of illicit materials during security check. The possible benefit of a multiplexed collimation system was examined.
Routledge Handbook Of Crime Science
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Author : Richard Wortley
language : en
Publisher: Routledge
Release Date : 2018-11-13
Routledge Handbook Of Crime Science written by Richard Wortley and has been published by Routledge this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-11-13 with Social Science categories.
Crime science is precisely what it says it is: the application of science to the phenomenon of crime. This handbook, intended as a crime science manifesto, showcases the scope of the crime science field and provides the reader with an understanding of the assumptions, aspirations and methods of crime science, as well as the variety of topics that fall within its purview. Crime science provides a distinctive approach to understanding and dealing with crime: one that is outcome-oriented, evidence-based and that crosses boundaries between disciplines. The central mission of crime science is to find new ways to cut crime and increase security. Beginning by setting out the case for crime science, the editors examine the roots of crime science in environmental criminology and describe its key features. The book is then divided into two sections. The first section comprises chapters by disciplinary specialists about the contributions their sciences can make or have already made to crime science. Chapter 12 of this book is freely available as a downloadable Open Access PDF under a Creative Commons Attribution-Non Commercial-No Derivatives 3.0 license. https://s3-us-west-2.amazonaws.com/tandfbis/rt-files/docs/Open+Access+Chapters/9780415826266_oachapter12.pdf
Fragment Based Drug Discovery And X Ray Crystallography
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Author : Thomas G. Davies
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-01-23
Fragment Based Drug Discovery And X Ray Crystallography written by Thomas G. Davies and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-01-23 with Science categories.
Introduction to Fragment-Based Drug Discovery, by Daniel A. Erlanson Fragment Screening Using X-Ray Crystallography, by Thomas G. Davies and Ian J. Tickle Hsp90 Inhibitors and Drugs from Fragment and Virtual Screening, by Stephen Roughley, Lisa Wright, Paul Brough, Andrew Massey and Roderick E. Hubbard Combining NMR and X-ray Crystallography in Fragment-Based Drug Discovery: Discovery of Highly Potent and Selective BACE-1 Inhibitors, by Daniel F. Wyss, Yu-Sen Wang, Hugh L. Eaton, Corey Strickland, Johannes H. Voigt, Zhaoning Zhu and Andrew W. Stamford Combining Biophysical Screening and X-Ray Crystallography for Fragment-Based Drug Discovery, by Michael Hennig, Armin Ruf and Walter Huber Targeting Protein–Protein Interactions and Fragment-Based Drug Discovery, by Eugene Valkov, Tim Sharpe, May Marsh, Sandra Greive and Marko Hyvönen Fragment Screening and HIV Therapeutics, by Joseph D. Bauman, Disha Patel and Eddy Arnold Fragment-Based Approaches and Computer-Aided Drug Discovery, by Didier Rognan
Two Dimensional X Ray Diffraction
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Author : Bob B. He
language : en
Publisher: John Wiley & Sons
Release Date : 2018-06-26
Two Dimensional X Ray Diffraction written by Bob B. He and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-06-26 with Science categories.
An indispensable resource for researchers and students in materials science, chemistry, physics, and pharmaceuticals Written by one of the pioneers of 2D X-Ray Diffraction, this updated and expanded edition of the definitive text in the field provides comprehensive coverage of the fundamentals of that analytical method, as well as state-of-the art experimental methods and applications. Geometry convention, x-ray source and optics, two-dimensional detectors, diffraction data interpretation, and configurations for various applications, such as phase identification, texture, stress, microstructure analysis, crystallinity, thin film analysis, and combinatorial screening are all covered in detail. Numerous experimental examples in materials research, manufacture, and pharmaceuticals are provided throughout. Two-dimensional x-ray diffraction is the ideal, non-destructive analytical method for examining samples of all kinds including metals, polymers, ceramics, semiconductors, thin films, coatings, paints, biomaterials, composites, and more. Two-Dimensional X-Ray Diffraction, Second Edition is an up-to-date resource for understanding how the latest 2D detectors are integrated into diffractometers, how to get the best data using the 2D detector for diffraction, and how to interpret this data. All those desirous of setting up a 2D diffraction in their own laboratories will find the author’s coverage of the physical principles, projection geometry, and mathematical derivations extremely helpful. Features new contents in all chapters with most figures in full color to reveal more details in illustrations and diffraction patterns Covers the recent advances in detector technology and 2D data collection strategies that have led to dramatic increases in the use of two-dimensional detectors for x-ray diffraction Provides in-depth coverage of new innovations in x-ray sources, optics, system configurations, applications and data evaluation algorithms Contains new methods and experimental examples in stress, texture, crystal size, crystal orientation and thin film analysis Two-Dimensional X-Ray Diffraction, Second Edition is an important working resource for industrial and academic researchers and developers in materials science, chemistry, physics, pharmaceuticals, and all those who use x-ray diffraction as a characterization method. Users of all levels, instrument technicians and X-ray laboratory managers, as well as instrument developers, will want to have it on hand.
Improving Sers Detection Of Illicit Drugs Using A Plasmonic Substrate Modified With Self Assembled Monolayers
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Author : John Harms
language : en
Publisher:
Release Date : 2021
Improving Sers Detection Of Illicit Drugs Using A Plasmonic Substrate Modified With Self Assembled Monolayers written by John Harms and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021 with categories.
Due to the worsening national drug epidemic and increasing prevalence of exceptionally potent synthetic opioids, there is a need to improve the forensic detection of illicit drugs, including sample analyses conducted on-site. In this thesis, the analysis of several illicit drugs spotted onto plasmonic surfaces was investigated using surface-enhanced Raman spectroscopy (SERS) with the goal of improving detection limits. Plasmonic surfaces (gold nanoparticle-loaded filter papers) were prepared and characterized prior to their SERS applications. Plasmonic surfaces were then further modified for improved SERS detection of each illicit drug with the treatment of self-assembled monolayer (SAM) forming compounds; in addition to the implementation of paper-spray ionization (PSI). Each of these modifications were optimized both independently and simultaneously for each drug through the screening process of many SAMs, durations of PSI, and SERS scan location on the sample surface. Finally, each combination of drug with optimal SAM and/or PSI optimization was calibrated to assess limits of detection. Limits of detection were found to be in the single-nanograms of drug deposited and improvements were observed in samples modified with SAMs and PSI.
Determination Of Drugs By X Ray Diffraction Ultraviolet And Infrared Spectrophotometry And By Microchemical Color And Crystal Reactions
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Author : Royal Canadian Mounted Police. Crime Detection Laboratories. Seminar
language : en
Publisher:
Release Date : 1954
Determination Of Drugs By X Ray Diffraction Ultraviolet And Infrared Spectrophotometry And By Microchemical Color And Crystal Reactions written by Royal Canadian Mounted Police. Crime Detection Laboratories. Seminar and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1954 with Chemistry, Forensic categories.
Comprehensive Supramolecular Chemistry Ii
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Author : George W. Gokel
language : en
Publisher: Elsevier
Release Date : 2017-06-22
Comprehensive Supramolecular Chemistry Ii written by George W. Gokel and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-06-22 with Science categories.
Comprehensive Supramolecular Chemistry II, Second Edition, Nine Volume Set is a ‘one-stop shop’ that covers supramolecular chemistry, a field that originated from the work of researchers in organic, inorganic and physical chemistry, with some biological influence. The original edition was structured to reflect, in part, the origin of the field. However, in the past two decades, the field has changed a great deal as reflected in this new work that covers the general principles of supramolecular chemistry and molecular recognition, experimental and computational methods in supramolecular chemistry, supramolecular receptors, dynamic supramolecular chemistry, supramolecular engineering, crystallographic (engineered) assemblies, sensors, imaging agents, devices and the latest in nanotechnology. Each section begins with an introduction by an expert in the field, who offers an initial perspective on the development of the field. Each article begins with outlining basic concepts before moving on to more advanced material. Contains content that begins with the basics before moving on to more complex concepts, making it suitable for advanced undergraduates as well as academic researchers Focuses on application of the theory in practice, with particular focus on areas that have gained increasing importance in the 21st century, including nanomedicine, nanotechnology and medicinal chemistry Fully rewritten to make a completely up-to-date reference work that covers all the major advances that have taken place since the First Edition published in 1996
Us Mexico Bi National Performance Measures Of Effectiveness
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Author :
language : en
Publisher:
Release Date : 1999
Us Mexico Bi National Performance Measures Of Effectiveness written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999 with Drug control categories.