Organ Selective Actions Of Steroid Hormones
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Organ Selective Actions Of Steroid Hormones
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Author : D.T. Baird
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-09
Organ Selective Actions Of Steroid Hormones written by D.T. Baird and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-09 with Medical categories.
Steroids regulate differentiation, growth and functioning of many tissues via a nuclear receptor gene activation mechanism. Molecular biology has opened the way for more detailed investigation of the complex set of intracellular interactions contributing to organ-selective actions of steroids and steroid-like compounds such as vitamin D. In this volume leading experts address basic molecular mechanisms of tissue specificity and related issue, with the goal of attaining a better understanding of the underlying mechanisms of organ selective actions of steroids. Discussed is the extent to which tissue specificity might selectively be modified by chemical modification of the hormones and how this may be applied towards improved therapies by taking advantage of tissue selectivity.
Organ Selective Actions Of Steroid Hormones
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Author : David T. Baird
language : en
Publisher: Springer Verlag
Release Date : 1995-01-01
Organ Selective Actions Of Steroid Hormones written by David T. Baird and has been published by Springer Verlag this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995-01-01 with Science categories.
Diagnosis And Management Of Ovarian Disorders
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Author : Albert Altchek
language : en
Publisher: Elsevier
Release Date : 2003-09-04
Diagnosis And Management Of Ovarian Disorders written by Albert Altchek and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-09-04 with Medical categories.
This updated second edition of Diagnosis and Management of Ovarian Disorders provides thorough, yet succinct insight into the ever-changing realm of ovarian disorders. It presents a novel multidisciplinary approach to the subject as described by clinicians, surgeons, pathologists, basic scientists and related medical researchers. Topics covered include reproductive technology, early diagnosis of ovarian cancer, and management of menopause among others. The breadth of information provided by this book will appeal to clinicians and researchers involved in the study and treatment of ovarian disorders. KEY FEATURES* Includes updated information on early diagnosis of ovarian cancer* Reviews new diagnostic techniques for ovarian disorders* Discusses latest information on reproductive technology* Presents translational treatment linking laboratory research with clinical medicine
Steroid Hormone Action
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Author : Malcolm G. Parker
language : en
Publisher: IRL Press
Release Date : 1993
Steroid Hormone Action written by Malcolm G. Parker and has been published by IRL Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993 with Medical categories.
This volume provides a detailed overview of the mechanisms by which steroid hormones regulate gene activity in target cells. It should be of interest to molecular biologists, endocrinologists, pharmacologists and clinicians interested in gene regulation hormones and steroid antagonists.
Testicular Tangrams
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Author : F.F.G. Rommerts
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-06-29
Testicular Tangrams written by F.F.G. Rommerts and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-29 with Medical categories.
During the past two decades research on the testis has created a vast number of publications. New techniques, such as cell and gene clon ing, germ cell manipulation and transplantation, as well as gene ex pression, have surpassed the classical approaches that involved studies on receptor activation and endocrine, paracrine and autocrine regula tory mechanisms. Due to the expansion of this field of research it has become increasingly difficult to integrate the large number of observa tions and relate them to the physiology and pathophysiology of the tes tis. More emphasis must, therefore, be put on the integration of isolated findings and the construction of the total picture. In order to stimulate this specific mental activity we have named this book Testicular Tan gram. We hope that the chapters in this book will be used as pieces of the testicular puzzle and that the reader enjoys composing new shapes. The chapters of this book are representative of the plenary lectures presented at the I ih European Workshop on Molecular and Cellular Endocrinology of the Testis held in Doorwerth The Netherlands, from April 6 - I 0, 2002. Publication of this book has been made possible by the generous support of the Ernst Schering Research Foundation. We would also like to thank the distinguished scientists, who have pro vided us with their excellent manuscripts well before the start of the Workshop. We acknowledge the help of Dr. U. -F. Habenicht, Dr. M.
Advances In Eicosanoid Research
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Author : C.N. Serhan
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-14
Advances In Eicosanoid Research written by C.N. Serhan and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-14 with Science categories.
Over the last few years, we have witnessed tremendous progress in the field of eicosanoids and their therapeutic applications. Receptor an tagonists for leukotrienes have been tested as anti-inflammatories and are on the market as a treatment for asthma. Receptor agonists for pro stacyclin are being tested for the treatment of peripheral vascular dis ease, and selective inhibitors of cyclooxygenase type II were just ap proved for the treatment of rheumatoid arthritis. All these developments are the culmination of many years and man-hours of careful research. The field has now entered an upswing that will result in novel thera peutic applications within the next 10 years. New molecules and me diators have been identified, new enzymes and pathways elucidated and new therapeutic approaches have emerged. The concept of ei cosanoids as "pro-inflammatory" molecules is being challenged, and their role as regulators is increasingly recognized. In fact, some of these molecules may be important endogenous anti-inflammatory agents.
Pet Chemistry
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Author : P.A. Schubiger
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-01-19
Pet Chemistry written by P.A. Schubiger and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-01-19 with Science categories.
Personalized medicine employing patient-based tailor-made therapeutic drugs is taking over treatment paradigms in a variety of ?elds in oncology and the central nervous system. The success of such therapies is mainly dependent on ef?cacious therapeutic drugs and a selective imaging probe for identi?cation of potential responders as well as therapy monitoring for an early bene?t assessment. Molecular imaging (MI) is based on the selective and speci?c interaction of a molecular probe with a biological target which is visualized through nuclear, magnetic resonance, near infrared or other methods. Therefore it is the method of choice for patient selection and therapy monitoring as well as for speci?c e- point monitoring in modern drug development. PET (positron emitting tomography), a nuclear medical imaging modality, is ideally suited to produce three-dimensional images of various targets or processes. The rapidly increasing demand for highly selective probes for MI strongly pushes the development of new PET tracers and PET chemistry. ‘PET chemistry’ can be de?ned as the study of positron-emitting compounds regarding their synthesis, structure, composition, reactivity, nuclear properties and processes and their properties in natural and - natural environments. In practice PET chemistry is strongly in?uenced by the unique properties of the radioisotopes used (e. g. , half-life, che- cal reactivity, etc. ) and integrates scienti?c aspects of nuclear-, organic-, inorganic- and biochemistry.
The Promises And Challenges Of Regenerative Medicine
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Author : John Morser
language : en
Publisher: Springer Science & Business Media
Release Date : 2005-07-06
The Promises And Challenges Of Regenerative Medicine written by John Morser and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-07-06 with Science categories.
Melanocyte system for studying stem cell niche -- Establishment and maniupulation of monkey and human embryonic stem cell lines for biomedical research -- Human embryonic stem cell derivation -- In search of the elusive epidermal stem cell -- Corneal cells for regeneration -- Polycomb gene product Bmi-l -- Directed differentiation of neural and sensory tissues from embryonic stem cells in vitro -- Stem cell biology for vascular regeneration.
Testis Epididymis And Technologies In The Year 2000
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Author : B. Jegou
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-06-29
Testis Epididymis And Technologies In The Year 2000 written by B. Jegou and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-29 with Medical categories.
A number of chapters present the most novel research on testicular and epididymal functions or on more general fields of hormone action and molecular cell biology as it is now a tradition. However, exceptionally, the book also contains several chapters dealing with the "Approaches and Tools in the Third Millenium". The unusual inclusion of technologies as such in the 2000 edition of the workshop was an absolute necessity, as these technologies are revolutionizing the fields of biology and medicine and, in many instances, how to do research. This volume gives the scientific community essential information about the very latest technical developments and their potential for future progress.
Regenerative And Cell Therapy
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Author : A. Keating
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-01-19
Regenerative And Cell Therapy written by A. Keating and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-01-19 with Medical categories.
This book gives an updated review of the state of the art in regenerative cell therapy in the fields of cardiology, hematology, pediatrics, neurology, orthopedics and infectious diseases. The book emphasizes clinical advances as proof of concept in cell therapy based on the revolutionizing observation that regeneration can occur throughout the body even in highly differentiated organs like the heart and the neuronal system. It provides examples of breakthroughs in the clinical implementation of adult stem cell therapy.