Osteoimmunology
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Principles Of Osteoimmunology
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Author : Peter Pietschmann
language : en
Publisher: Springer
Release Date : 2016-08-18
Principles Of Osteoimmunology written by Peter Pietschmann and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-08-18 with Medical categories.
This fully updated and extended second edition provides a comprehensive overview on the basic concepts of the rapidly developing field of osteoimmunology and also offers in-depth insights into the molecular mechanisms of bone diseases. Clinical data is presented and put into context with the latest research findings. This second edition in addition discusses the latest topics in transplantation immunology. The book addresses scientists and physicians working in immunology, pathophysiology and osteology.
Updates On Osteoimmunology What S New On The Crosstalk Between Bone And Immune Cells
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Author : Giacomina Brunetti
language : en
Publisher: Frontiers Media SA
Release Date : 2020-03-24
Updates On Osteoimmunology What S New On The Crosstalk Between Bone And Immune Cells written by Giacomina Brunetti and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-03-24 with categories.
Osteoimmunology
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Author : Joseph Lorenzo
language : en
Publisher: Academic Press
Release Date : 2010-09-24
Osteoimmunology written by Joseph Lorenzo and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-09-24 with Medical categories.
Bone and the immune system are both complex tissues, which, respectively, regulate the skeleton and the body's responses to invading pathogens. Critical interactions between these two organ systems frequently occur, particularly in the development of immune cells in the bone marrow and for the function of bone cells in health and disease. This book provides a detailed overview of the many ways that bone and immune cells interact. The goal is to provide basic and clinical scientists with a better understanding of the role that the immune system and bone play in the development and function of each other so that advances in both fields will be facilitated. The focus of the book will be both on basic pathways and translational science, which will apply basic knowledge to clinical diseases. Chapter content will range from basic descriptions of the various cell systems and their development to the signals that cause them to interact during normal physiology and disease. This is a rapidly developing area that is of interest to a wide spectrum of researchers, students, and fellows in immunology, rheumatology, hematology, and bone biology--all of whom need to develop a more complete understanding of their previously separate disciplines and the mechanisms by which they interact. Presents a comprehensive, translational source for all aspects of osteoimmunology in one reference work Experts in bone biology and immunology (from all areas of academic and medical research) take readers from the bench research (cellular and molecular mechanism), through genomic and proteomic analysis, all the way to clinical analysis (histopathology and imaging) and new therapeutic approaches Clear presentations by bone biologists of the cellular and molecular mechanisms underlying bone cell development leading to bone and immunological diseases such as Lupus Clear presentations by immunologists of how immune cells develop and how the immune system plays a role in bone diseases like osteoporosis and arthritis
Advances In Osteoimmunology
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Author : Claudine Blin-Wakkach
language : en
Publisher: Frontiers Media SA
Release Date : 2020-01-21
Advances In Osteoimmunology written by Claudine Blin-Wakkach and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-01-21 with categories.
Osteoimmunology
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Author : Joseph Lorenzo
language : en
Publisher: Academic Press
Release Date : 2015-09-23
Osteoimmunology written by Joseph Lorenzo and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-09-23 with Medical categories.
Osteoimmunology: Interactions of the Immune and Skeletal Systems, Second Edition, explores the advancements that have been made in the field during the last 40 years, including valuable information on our understanding of the interactions between hematopoietic, immune, and bone cells, now known as the field of osteoimmunology. This comprehensive work offers the most extensive summaries of research trends in the field and their translation into new therapeutics. Early chapters deal with the development of osteoblasts, osteoclasts, hematopoietic stem cells, T and B-lymphocytes, and communications between these cellular elements, while later sections contain discussions of the signaling pathways by which RANKL influences osteoclast development and function. Subsequent chapters explore the effects that estrogen has on bone and the immune system, the development of pathologic conditions, and the growing research around osteoporosis, Paget’s disease, the genetics of bone disease, and bone cancer metastasis. Explains the intricate interaction between the immune system and bone Features detailed discussions of the key cellular and molecular mechanisms governing the homeostasis of the individual systems Facilitates greater understanding of osteoimmunologic networks, their environments, and how this understanding leads to better treatments for human diseases involving both systems
Osteoimmunology
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Author : Yongwon Choi
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-12-01
Osteoimmunology written by Yongwon Choi and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-12-01 with Medical categories.
It has only recently been appreciated that the immune and skeletal systems have major interactions. It is now well documented that osteoclasts, which are important cellular mediators of skeletal homeostasis, are derived from hematopoietic precursors that also give rise to immune cells. In addition, numerous cytokines that were first shown to regulate immune cell function have also been demonstrated to regulate bone cells and influence skeletal health. Conversely, products of bone cells appear critical for the engraftment of marrow in bone, the normal development of the hematopoietic and immune systems and provide niche for long-term memory B and T cells. In the past scientists involved in immune and bone cell investigations have rarely interacted in a significant way as these disciplines have developed independently and, for the most part, remain separate. The conference will bring together leading international scientists from both fields to interact so that new collaboration can develop and more rapid progress in understanding the relationships between these fields can be achieved. Short talks will be selected from abstracts from the international community. This conference will have a format to provide an environment of maximum interaction and interchange through lectures, posters, and open discussion.
Recent Advances In Basic And Translational Osteoimmunology
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Author : Rupesh K. Srivastava
language : en
Publisher: Frontiers Media SA
Release Date : 2022-01-10
Recent Advances In Basic And Translational Osteoimmunology written by Rupesh K. Srivastava and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-10 with Medical categories.
Osteoimmunology
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Author : Yongwon Choi
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-10-01
Osteoimmunology written by Yongwon Choi and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-10-01 with Medical categories.
A Key Regulator of Postnatal Skeletal Remodeling.- Ectodomain Shedding of Receptor Activator of NF-KB Ligand.- The Negative Role Of Ids In Osteoclastogenesis.- Functional Genetic and Genomic Analysis of Modeled Arthritis.- Dexamethsone Suppresses Bone Formation via the Osteoclast.- Immunologic Regulation Of Bone Development.- Pth Regulates The Hematopoietic Stem Cell Niche In Bone.- Regulation Of Hematopoietic Stem Cells In The Osteoblastic Niche.- The Chemokine Cxcl12 And Regulation Of Hsc And Lymphocyte Development In The Bone Marrow Niche.- Osteoclast Precursor Cells.- Interaction with estrogen receptors as treatment of arthritis and osteoporosis.- Novel Signaling Pathways And Therapeutic Targets In Osteoclasts.- The Enigmatic Function of TREM-2 in Osteoclastogenesis.- Role of cell-matrix interactions in osteoclast differentiation.- Positive and negative roles of IL-6, STAT3 and SOCS3 in inflammatory arthritis.- Control of Osteoclast activity and bone loss by IKK subunits: new targets for therapy.- Targeting Osteoporosis And Rheumatoid Arthritis By Active Vaccination Against Rankl.- RANKL Inhibition: From Mice to Men (and Women).
Updates On Osteoimmunology What S New On The Crosstalk Between Bone And Immune Cells
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Author : Giacomina Brunetti
language : en
Publisher:
Release Date : 2020
Updates On Osteoimmunology What S New On The Crosstalk Between Bone And Immune Cells written by Giacomina Brunetti and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020 with categories.
In the last twenty years, different discoveries have emphasized the cross-talk between bone and immune cells as well as their common regulatory pathways. Indeed, soluble molecules produced by immune cells modulate the behavior of osteoblasts and osteoclasts. Moreover, osteoclasts, the bone-resorbing cells, originate from the same myeloid precursor cells that differentiated into macrophages and myeloid dendritic cells. Whereas, the bone-forming osteoblastic cells control hematopoietic stem cell niches and thus immune cell ontology. The amplified recognition of the complex relationship between the immune system and bone led to the designation of osteoimmunology field. This Research Topic collects articles that highlight the cross-talk between bone and immune cells,
Recent Progress In Osteoimmunology
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Author : Melonie Armstrong
language : en
Publisher: American Medical Publishers
Release Date : 2023-09-19
Recent Progress In Osteoimmunology written by Melonie Armstrong and has been published by American Medical Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-09-19 with Medical categories.
Osteoimmunology is the study of the correlation between bone and immune cells. It emphasizes the two sided communication that takes place among the immune cells and bones. The interactions taking place between the immune system and bone are critical in maintaining skeletal homeostasis. The bone marrow cavity is essential for the growth of the immune system. It also houses crucial stem cells for maintaining the immune system. Immune cells create cytokines, which have crucial effects on the modulation of bone homeostasis. There are a few critical cytokines, which are produced by the immune system, such as TNF-α, RANKL, IFNs, M-CSF and ILs. These affect the activity and differentiation of bone resorption and osteoclasts. This book is a valuable compilation of topics, ranging from the basic to the most complex advancements in the field of osteoimmunology. It will prove to be immensely beneficial to students and researchers in this field.