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Pain Research


Pain Research
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Advances In Pain Research Mechanisms And Modulation Of Chronic Pain


Advances In Pain Research Mechanisms And Modulation Of Chronic Pain
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Author : Bai-Chuang Shyu
language : en
Publisher: Springer
Release Date : 2018-10-10

Advances In Pain Research Mechanisms And Modulation Of Chronic Pain written by Bai-Chuang Shyu and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-10-10 with Medical categories.


This book summarizes the latest advances in pain research. All the chapters were contributed by speakers from Asian Pain Symposium (APS) on Acute and Chronic Pain, which was held in Taipei in 2017. Founded in Kyoto, Japan in 2000, the APS serves as a platform for scientists to present recent findings in pain research and discuss research orientation in this field. APS 2017 focused on novel strategies for pain treatment. Written by experts from various disciplines, from molecular to functional, and from basic to clinic studies, this book is composed of 18 review articles on the physiology and pathology of pain in these research fields. Specific topics include circuitry, neurotransmitter, physiology, behavior, neuropathology, pharmacology, and the treatments for neuropathic pain disorders. The book is a valuable resource for researchers and graduate students in pain medicine and neuroscience.



Methods In Pain Research


Methods In Pain Research
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Author : Lawrence Kruger
language : en
Publisher: CRC Press
Release Date : 2001-06-22

Methods In Pain Research written by Lawrence Kruger and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-06-22 with Health & Fitness categories.


In the past two decades, pain research has become one of the most rapidly growing areas of neuroscience activity. Methods in Pain Research brings together in a single volume a survey of the methods that can be used to study a reaction or 'sensory report' in humans that can only be inferred by indirect means in animal or tissues studies. It presents



Pain Research


Pain Research
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Author :
language : en
Publisher:
Release Date : 1986

Pain Research written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1986 with Pain categories.




Pain Research


Pain Research
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Author : Z. David Luo
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-02-02

Pain Research written by Z. David Luo and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-02-02 with Medical categories.


The detrimental impacts of pain on the quality of our daily life have drawn increasing attention from researchers, health care providers, policymakers, and social workers. The reality of effective painkillers specifically designed for different types of pain states has been obscured by missing knowledge of the mechanisms of different types of pain. Thus, studying the complexity of pain transduction, which includes various insults to the peripheral nervous systems, sensitized spinal circuits, and altered signals ascending to or descending from the brain, has emerged as a high priority task on the agenda of pharmaceutical companies and other private as well as public agencies. To accomplish this mission, one requires a combination of well-integrated systems, such as a- mal models resembling the pathological conditions of pain transduction, and an understanding of the interactions among pain transducers and mediators at the molecular level. Thanks to rapid advancements in the development of novel cellular and molecular biology techniques, as well as in our understanding of physiology, and of the behavioral pharmacology of pain transduction, the time is now ripe for dissecting the molecular mechanisms of pain transduction using multidisciplinary approaches. Indeed, my acceptance of the invitation from the series editor, Dr. John Walker, to assemble a book of methods and protocols for pain research was inspired by these emerging needs. The purpose of Pain Research: Methods and Protocols is to provide st- by-step methods and protocols of multidisciplinary approaches related to the study of pain transduction.



Translational Pain Research Comparing Preclinical Studies And Clinical Pain Management Lost In Translation


Translational Pain Research Comparing Preclinical Studies And Clinical Pain Management Lost In Translation
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Author : Jianren Mao
language : en
Publisher: Nova Publishers
Release Date : 2006

Translational Pain Research Comparing Preclinical Studies And Clinical Pain Management Lost In Translation written by Jianren Mao and has been published by Nova Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006 with Pain categories.


Basic science and clinical pain research is particularly challenging for several reasons. First, pain is a subjective experience in response to nociception that follows actual or potential tissue damage. Since the ability to respond to this warning signal is essential for our survival, the nociceptive system that produces and transmits nociceptive signals is remarkably redundant and involves diffuse regions of the central nervous system. Second, unlike other sensory modalities, pain is a multi-dimensional experience including at least cognitive, affective, and sensory-discriminative components. Third, pain experiences can be influenced by psychological, socioeconomic, cultural, and genetic predispositions, making it exceedingly complicated to study pain and pain modulation. The topics covered in this volume are carefully selected and directly related to the daily practice of pain medicine. These topics include 1) central mechanisms of pain and pain modulation (Dickenson, Donovan-Rodriguez, Mattews) and clinical use of ion channel blockers (Chen); 2) spinal glutamatergic mechanisms (Guo, Dubner, Ren) and issues related to glutamate receptor antagonists in pain management (Mao); 3) basic science of opioid analgesics (Gintzler, Chakrabarti) and clinical opioid use (Smith, McCleane); 4) inflammatory cytokines (Samad) and clinical use of anti-inflammatory drugs (Fink, Brenner); 5) role of the sympathetic nervous system in pain mechanisms and its relation to clinical pain management (Sharma, Raja); 6) preclinical studies on tricyclic antidepressants (Gerner, Wang) and clinical use of antidepressants in pain management (Greenberg); 7) developing pain pathways and analgesic mechanisms during the developmental stage (Fitzgerald) and challenges of pediatric pain management (Lebel); 8) basic science mechanisms of serotonin agonists and their use in the clinical management of migraine headache (Biondi); 9) clinical research on gender differences in clinical pain and their implications for clinical pain management (Holdcroft); 10) current modalities of clinical cancer pain management (Popescu, Hord); and 11) preclinical and clinical information on alternative medicine (Chen).



Translational Pain Research


Translational Pain Research
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Author : Lawrence Kruger
language : en
Publisher: CRC Press
Release Date : 2009-11-24

Translational Pain Research written by Lawrence Kruger and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-11-24 with Health & Fitness categories.


One of the Most Rapidly Advancing Fields in Modern Neuroscience The success of molecular biology and the new tools derived from molecular genetics have revolutionized pain research and its translation to therapeutic effectiveness. Bringing together recent advances in modern neuroscience regarding genetic studies in mice and humans and the practical



Relieving Pain In America


Relieving Pain In America
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Author : Institute of Medicine
language : en
Publisher: National Academies Press
Release Date : 2011-10-26

Relieving Pain In America written by Institute of Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-10-26 with Medical categories.


Chronic pain costs the nation up to $635 billion each year in medical treatment and lost productivity. The 2010 Patient Protection and Affordable Care Act required the Department of Health and Human Services (HHS) to enlist the Institute of Medicine (IOM) in examining pain as a public health problem. In this report, the IOM offers a blueprint for action in transforming prevention, care, education, and research, with the goal of providing relief for people with pain in America. To reach the vast multitude of people with various types of pain, the nation must adopt a population-level prevention and management strategy. The IOM recommends that HHS develop a comprehensive plan with specific goals, actions, and timeframes. Better data are needed to help shape efforts, especially on the groups of people currently underdiagnosed and undertreated, and the IOM encourages federal and state agencies and private organizations to accelerate the collection of data on pain incidence, prevalence, and treatments. Because pain varies from patient to patient, healthcare providers should increasingly aim at tailoring pain care to each person's experience, and self-management of pain should be promoted. In addition, because there are major gaps in knowledge about pain across health care and society alike, the IOM recommends that federal agencies and other stakeholders redesign education programs to bridge these gaps. Pain is a major driver for visits to physicians, a major reason for taking medications, a major cause of disability, and a key factor in quality of life and productivity. Given the burden of pain in human lives, dollars, and social consequences, relieving pain should be a national priority.



Pain Models


Pain Models
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Author : Hermann O. Handwerker
language : en
Publisher: Lippincott Williams & Wilkins
Release Date : 2015-06-01

Pain Models written by Hermann O. Handwerker and has been published by Lippincott Williams & Wilkins this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-06-01 with Medical categories.


The neurobiology and mechanisms discovered in animals often do not translate to patients with a chronic pain condition. To help researchers and clinicians develop and use models that can help translate data from animals into humans, this book presents experimental animal models, with a focus on how they may translate into humans human experimental pain models, including details about pain induction and assessment human surrogate pain models clinical applications of pain models models that may link mechanisms of pain and pruritus Pain Models contains 29 chapters by internationally recognized experts. It is a comprehensive survey of pain models at different levels, and commentaries by clinicians directly address clinical perspectives. This unique book is unprecedented in its content. It's a quick reminder of the hard work needed to investigate the complex issue of pain perception. With the advent of increasingly sensitive noninvasive investigational tools, the authors want readers to know that basic research is still needed to help develop new drugs. This book will enrich anyone who wishes to know all that goes into conducting pain research with a lab-based pain model.



Pain Research And Treatment


Pain Research And Treatment
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Author :
language : en
Publisher:
Release Date : 1975

Pain Research And Treatment written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1975 with categories.




Advances In Pain Research And Therapy


Advances In Pain Research And Therapy
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Author :
language : en
Publisher:
Release Date : 1987

Advances In Pain Research And Therapy written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1987 with Pain categories.


Vol. 1 consists of the Proceedings of the 1st World Congress on Pain.