Paracoccidioidomycosis
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Paracoccidioidomycosis
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Author : M. Franco M.D.
language : en
Publisher: CRC Press
Release Date : 2018-01-31
Paracoccidioidomycosis written by M. Franco M.D. and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-01-31 with Science categories.
Paracoccidioidomycosis continues to be a serious health problem among rural workers in many Latin American countries. This deep mycosis has many similarities to other deep mycoses that affect the developed world. Furthermore, P. brasiliensis is becoming an excellent tool for basic studies (e.g., dimorphism, hormone-mediated host interactions, ecology). Paracoccidioidomycosis is an important publication with 30 chapters covering every aspect of the disease from its etiological agent, P. brasiliensis, to the clinical manifestations and treatment. The chapters are written by 45 specialists, each one a leading figure in his or her area of research. This reference is the first of its kind to be written in English. The book is a valuable addition to the reference collections of basic researchers and applied mycologists, as well as clinicians and others working with infectious and tropical diseases. It can also be used for courses on medical mycology.
Paracoccidioidomycosis
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Author : M. Franco M.D.
language : en
Publisher:
Release Date : 2017
Paracoccidioidomycosis written by M. Franco M.D. and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017 with Electronic books categories.
"Paracoccidioidomycosis continues to be a serious health problem among rural workers in many Latin American countries. This deep mycosis has many similarities to other deep mycoses that affect the developed world. Furthermore, P. brasiliensis is becoming an excellent tool for basic studies (e.g., dimorphism, hormone-mediated host interactions, ecology). Paracoccidioidomycosis is an important publication with 30 chapters covering every aspect of the disease from its etiological agent, P. brasiliensis, to the clinical manifestations and treatment. The chapters are written by 45 specialists, each one a leading figure in his or her area of research. This reference is the first of its kind to be written in English. The book is a valuable addition to the reference collections of basic researchers and applied mycologists, as well as clinicians and others working with infectious and tropical diseases. It can also be used for courses on medical mycology."--Provided by publisher.
Paracoccidioidomycosis
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Author :
language : en
Publisher:
Release Date : 1972
Paracoccidioidomycosis written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1972 with categories.
Paracoccidioidomycosis
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Author : Marcello F. Franco, M.D.
language : en
Publisher: CRC Press
Release Date : 1993-12-17
Paracoccidioidomycosis written by Marcello F. Franco, M.D. and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993-12-17 with Science categories.
Paracoccidioidomycosis continues to be a serious health problem among rural workers in many Latin American countries. This deep mycosis has many similarities to other deep mycoses that affect the developed world. Furthermore, P. brasiliensis is becoming an excellent tool for basic studies (e.g., dimorphism, hormone-mediated host interactions, ecology). Paracoccidioidomycosis is an important publication with 30 chapters covering every aspect of the disease from its etiological agent, P. brasiliensis, to the clinical manifestations and treatment. The chapters are written by 45 specialists, each one a leading figure in his or her area of research. This reference is the first of its kind to be written in English. The book is a valuable addition to the reference collections of basic researchers and applied mycologists, as well as clinicians and others working with infectious and tropical diseases. It can also be used for courses on medical mycology.
Paracoccidioidomycosis Proceedings Of The First Pan American Symposium 25 27 October 1971 Medellin Colombia
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Author :
language : en
Publisher:
Release Date : 1972
Paracoccidioidomycosis Proceedings Of The First Pan American Symposium 25 27 October 1971 Medellin Colombia written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1972 with categories.
Paracoccidioidomycosis In A University Hospital Of Buenos Aires City
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Author : N B Fernandez
language : en
Publisher:
Release Date : 2017
Paracoccidioidomycosis In A University Hospital Of Buenos Aires City written by N B Fernandez and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017 with categories.
PARACOCCIDIOIDOMYCOSIS IN A UNIVERSITY HOSPITAL OF BUENOS AIRES CITYM Sc Fernu00e1ndez Norma 1, Ph D Canteros Cristina 2,Faru00edas Luciana 1 ,MSc Toranzo Adriana 2, Ph DTiraboschi Nora1, , Stecher Daniel 1. 1 Micologu00eda Divisiu00f3n Infectologu00eda. Hospital de Clu00ednicas u201cJosu00e9 de San Martu00ednu201d. Universidad de Buenos Aires. 2 Departamento Micologu00eda INEI- ANLIS u201cDr. C G. Malbru00e1nu201d. Buenos Aires. ArgentinaParacoccidioidomycosis (PCM) is a systemic and endemic fungal disease that is restricted to Latin America. In Argentina, the endemic area is located north of the 34 u00ba S parallel. Diagnosis is made by visualization of the yeast cells of Paracoccidioides spp in tissues, fungal isolation and anti-Paracoccidioides antibodies detection.OBJECTIVE: To report cases of PCM treated in a university hospital in the city of Buenos Aires, Argentina.MATERIALS: Retrospective study. Source documents were medical records from patients with PCM diagnosed from 2002 to 2017. Demographic, clinical and laboratory data are described.RESULTS: The total number of patients diagnosed with PCM was 22. All patients were adult men with an average age of 53 years (range 29 to 72 years); 11/22 (50%) were natives and still lived in endemic area at the time of diagnosis. A total of 10/22 (45%) of the patients had been born in this area but had migrated years ago to Buenos Aires (between 11 to 45 years). Only one patient was born in the metropolitan Buenos Aires region and had not visited the endemic area of PCM. In 17/22 (77%) of patients multifocal lessions (lung and other organs) were observed while in 5/22 (23%) unifocal lessions (1 in cerebellum, 1 in adrenal glands, 1 in larynx, 1 in ropes vowels and 1 in lymph node) were found. Paracoccidiodes spp. / Leishmania spp. co-infection was documented in one patient in 2017.In 16 of 22 (72%) patients multi-budding yeast cells (pilot's wheel) of Paraccocidiodes spp. were observed in fresh examination and / or with histopathological techniques of different samples. The fungus was isolated in pure culture only in three patients. In 12 of 22 (54%) patients specific anti-Paracoccidoides antibodies were detected using the immunodifussion (ID) test. Positive ID was the only confirmatory test for diagnosis in 5 of these patients. Nested PCR amplified a GP43 gene fragment in the last six cases from sputum samples, biopsies from adrenal glands, larynx, vocal cords and oral mucosa. In five of these cases multi-budding yeast cells were observed and in one case direct examination was negative. All patients received itraconazole antifungal treatment (100-400 mg/day). When follow-up was performed, favorable outcome was achieved in 12/18 (66%) cases.CONCLUSION: Buenos Aires City records few PCM cases. However, the large number of migrants from Argentinau2019s northern provinces and neighboring countries, where PCM is endemic, should be an alert for its diagnosis. Clinical suspicion and specific tests inclusion for its diagnosis are mandatory in patients who inhabit the PCM endemic area. It is also important to include the differential diagnosis with pathogens that share ecological and physiopathological similarities with PCM. Quick and efficient direct examination helps to diagnose most cases of PCM. On the other hand, culture, as reported in the literature, has low sensitivity. In addition, serology is also an important test and, sometimes, the only evidence of this mycosis.
Immunological Studies In Murine Paracoccidioidomycosis
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Author : Elizabeth Castañeda del Gordo
language : en
Publisher:
Release Date : 1985
Immunological Studies In Murine Paracoccidioidomycosis written by Elizabeth Castañeda del Gordo and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1985 with Mice categories.
Diagnosis Of Paracoccidioidomycosis In Sputum Of Immunocompromised Hosts By Polymerase Chain Reaction
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Author : Gerald Kayingo
language : en
Publisher:
Release Date : 2007
Diagnosis Of Paracoccidioidomycosis In Sputum Of Immunocompromised Hosts By Polymerase Chain Reaction written by Gerald Kayingo and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with Physicians' assistants categories.
Paracoccidioidomycosis
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Author : 1. Pan American Symposium (Medellin, Oct. 25-27, 1971)
language : en
Publisher:
Release Date : 1972
Paracoccidioidomycosis written by 1. Pan American Symposium (Medellin, Oct. 25-27, 1971) and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1972 with categories.
Sulfamethoxazole Dosage In Monitoring Of The Treatment Of Paracoccidioidomycosis Patients Treated With Cotrimoxazole
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Author : RS Cavalcante
language : en
Publisher:
Release Date : 2017
Sulfamethoxazole Dosage In Monitoring Of The Treatment Of Paracoccidioidomycosis Patients Treated With Cotrimoxazole written by RS Cavalcante and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017 with categories.
Sulfamethoxazole dosage in monitoring the treatment of paracoccidioidomycosis patients treated with cotrimoxazole.Introduction. Paracoccidioidomycosis (PCM) is one of the major systemic mycoses in Brazil, caused by fungi of the genus Paracoccidioides. Trimethoprim-sulfamethoxazole, also called cotrimoxazole (CMX), one of the drugs most used in the PCM treatment, can be monitored by the serum dosage of the sulfamethoxazole (SMX). Objective. The objective of this study was to evaluate the impact of serum levels of SMX during treatment in PCM patients treated with CMX on clinical and serological response. Methods. Thirty-six patients with a confirmed diagnosis of PCM, attended by the Department of Infectious Diseases of University Hospital of Botucatu Medical School - UNESP, from 1996 to 2013, were selected for this study. Clinical and laboratory data were obtained from medical records. Patients underwent monthly SMX dosing until clinical cure (initial treatment) and every three months until serologic cure (complementary treatment) was achieved. It was considered as SMX adequate serum levels when 80% or more of the measurements reached desired therapeutic values (70 mg/mL for initial treatment and 50 mg/mL for complementary treatment). The continuous variables were presented in median, 1st and 3rd quartiles and analyzed by the Mann-Whitney test, with p values lower than 0.05 being considered significant. Results. The 36 patients received CMX throughout the treatment of PCM. There was no difference in time to reach clinical cure between patients with the acute form with adequate levels [176 days (141 - 201)] and inadequate sulfa [195 days (123 - 251); p = 0.59]. However, in patients with chronic form (CF), clinical cure was shorter in those with adequate levels [96 days (55 - 126)] than in inadequate [224 days (147-319); p = 0.002]. The time to reach serological cure was also shorter in patients with CF with adequate levels [313 days (240 - 825)] than those with inadequate levels [720 days (473 - 1598); p = 0.04]. Patients who presented more than 80% of SMX serum levels above 70 mg/mL at initial treatment reached earlier clinical cure than those with SMX levels between 50u201370 mg/dL [126 days (77 u2013 159) vs. 201 days (173 u2013 236), p=0,02]. Conclusion. These findings demonstrate the great importance of serum monitoring of SMX levels during the PCM treatment with CMX for earlier clinical and serologic cure.