Paradoxical Effects Of Ssri Antidepressants When Treating Mood Dysregulation In Borderline Personality Disorder
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Paradoxical Effects Of Ssri Antidepressants When Treating Mood Dysregulation In Borderline Personality Disorder
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Author : Carlo Lazzari
language : en
Publisher:
Release Date : 2017
Paradoxical Effects Of Ssri Antidepressants When Treating Mood Dysregulation In Borderline Personality Disorder written by Carlo Lazzari and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017 with categories.
OBJECTIVEAntidepressants of the SSRI (Serotonin System Reuptake Inhibitors) are frequently prescribed in primary and secondary care to address depression. SSRI antidepressants are also frequently prescribed in patients with a borderline personality disorder (BPD) to address low mood. However, the author of the current research found paradoxical effects in the combination SSRI-BPD. There is current concern about the increase of suicidality and deliberate self harm in patients under SSRI. Authors suggest attention when SSRI are prescribed to children and adolescents as SSRI can trigger suicidal ideation and aggression [1-3]. However, evidence to show increased deliberate self harm in patients on SSRI is contradictory in several studies due to confounding variables [4].METHODSThe aim of psychiatric teams in primary and secondary care is to stabilize the presentation and to reduce deliberate self-harm and suicidal ideation in patients with BPD. Patients with BPD have mood dysregulation with dysthymia or cyclothymia. The BPD patientsu2019 narratives used for the study provided some evidence or paradoxical effects when SSRI antidepressants are used to address mood dysregulation in BPD. RESULTSPatients with BPD treated with SSRI antidepressants are at high risk of presenting with dose-related behavioral symptoms of serotonin activation including increased impulsivity, increased suicidal ideation and acts, increased violence towards others, increased deliberate self-harm, and increased agitation. Therefore, the paradoxical effect of SSRI is not age related in this group of patients.CONCLUSIONSThe use of SSRI antidepressants in BPD should receive a warning when used in BPD while the use of more sedative mood stabilizers should be considered instead.REFERENCES[1] Nischal A, Tripathi A, Nischal A, Trivedi JK. Suicide and Antidepressants: What Current Evidence Indicates. Mens Sana Monogr 2012; 10: 33-44.[2] Sharma T, Guski LS,Freund N, Gu00f8tzsche PC, Suicidality and aggression during antidepressant treatment: systematic review and meta-analyses based on clinical study reports. BMJ 2016;352:i65http://dx.doi.org/10.1136/bmj.i65[3] National Health Service. Antidepressants and suicide risk. 2009 (online) Available at: https://www.nhs.uk/news/mental-health/antidepressants-and-suicide-risk/[4] Didham RC, Connell DW, Blair HJ, Reith DM, Br J Clin Pharmacol. 2005 Nov; 60(5): 519u2013525. doi:10.1111/j.1365-2125.2005.02480.x.
Practice Guideline For The Treatment Of Patients With Borderline Personality Disorder
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Author : American Psychiatric Association
language : en
Publisher: American Psychiatric Pub
Release Date : 2001
Practice Guideline For The Treatment Of Patients With Borderline Personality Disorder written by American Psychiatric Association and has been published by American Psychiatric Pub this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001 with Medical categories.
The most common personality disorder here and abroad, borderline personality disorder is often misdiagnosed or underdiagnosed. Left untreated, it causes marked distress and impairment in social, occupational, and role functioning, with high rates of self-destructive behavior (attempted and completed suicide). Its pervasive pattern of impulsivity and instability of interpersonal relationships, affects, and self-image begins in early adulthood and presents in a variety of contexts. Developed primarily by psychiatrists in active clinical practice, the revised edition of this popular work offers an updated synthesis of current scientific knowledge and rational clinical practice for patients with borderline personality disorder--with the important caveat that clinicians should consider, but not limit themselves to, the treatments recommended here. The summary of treatment recommendations is keyed according to the level of confidence with which each recommendation is made and coded to show the nature of its supporting evidence. Highly informative and easy to use, this eminently practical volume is organized into three major parts: Part A contains treatment recommendations (Section I, treatment summaries; Section II, treatment plans; Section III, special clinical considerations; and Section IV, risk management issues during treatment), Part B presents the evidence underlying these treatment recommendations (Section V, an overview of DSM-IV-TR criteria, prevalence rates, and natural history and course; and Section VI, a review of existing treatment literature), and Part C summarizes those areas in which better research data are needed. Remarkably concise and comprehensive, this practice guideline continues to be an indispensable reference for every clinician who treats patients with this heterogeneous and complex disorder.
Practical Psychopharmacology
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Author : Joseph F. Goldberg
language : en
Publisher: Cambridge University Press
Release Date : 2021-04-29
Practical Psychopharmacology written by Joseph F. Goldberg and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-04-29 with Medical categories.
A practical guide translating clinical trials findings, across major psychiatric disorders, to devise tailored, evidence-based treatments.
The American Journal Of Psychiatry
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Author :
language : en
Publisher:
Release Date : 2001-10
The American Journal Of Psychiatry written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-10 with Psychiatry categories.
Essential Psychiatry
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Author : Robin M. Murray
language : en
Publisher: Cambridge University Press
Release Date : 2008-09-18
Essential Psychiatry written by Robin M. Murray and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-09-18 with Medical categories.
This is a major international textbook for psychiatrists and other professionals working in the field of mental healthcare. With contributions from opinion-leaders from around the globe, this book will appeal to those in training as well as to those further along the career path seeking a comprehensive and up-to-date overview of effective clinical practice backed by research evidence. The book is divided into cohesive sections moving from coverage of the tools and skills of the trade, through descriptions of the major psychiatric disorders and on to consider special topics and issues surrounding service organization. The final important section provides a comprehensive review of treatments covering all of the major modalities. Previously established as the Essentials of Postgraduate Psychiatry, this new and completely revised edition is the only book to provide this depth and breadth of coverage in an accessible, yet authoritative manner.
The American Psychiatric Publishing Textbook Of Personality Disorders
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Author : John M. Oldham
language : en
Publisher: American Psychiatric Pub
Release Date : 2007-04-02
The American Psychiatric Publishing Textbook Of Personality Disorders written by John M. Oldham and has been published by American Psychiatric Pub this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-04-02 with Medical categories.
Examine personality psychopathology from diverse perspectives and explore multiple research and treatment approaches with The American Psychiatric Publishing Textbook of Personality Disorders. Capture the multifaceted range of nonpathological human behavior and develop a judicious understanding of the extremes of behavior that are called personality disorders. No other textbook today matches the clinically useful scope and relevance of Textbook of Personality Disorders. Its comprehensive coverage of theory, research, and treatment of personality disorders, incorporating illustrative case examples to enhance understanding, reflects the work of more than 70 expert contributors who review the latest theories, research findings, and clinical expertise in the increasingly complex field of personality disorders. The deeply informative Textbook of Personality Disorders is organized into six main sections: Basic concepts -- Summarizes definitions and classifications of personality disorders, building on broader international concepts and theories of psychopathology and including categorical and dimensional models of personality disorders Clinical evaluation -- Discusses manifestations, problems in differential diagnosis, and patterns of comorbidity; the most widely used interviews and self-administered questionnaires; and the course and outcome of personality disorders. Etiology -- Includes an integrative perspective (personality disorders, personality traits, and temperament); epidemiology (one in ten people has a personality disorder) and genetics; neurobiology; antecedents of personality disorders in children and adolescents; attachment theory and mentalization therapy in borderline personality disorder; and the complex and variable interface between personality disorders and sociocultural factors Treatment -- Covers levels of care and the full range of therapies, from psychoanalysis to pharmacotherapy; includes detailed information on schema therapy, dialectical behavior therapy (specifically developed for self-injuring/suicidal patients with borderline personality disorder), interpersonal therapy, dynamically-informed supportive psychotherapy, group treatment, family therapy, psychoeducation, the therapeutic alliance, boundary issues, and collaborative treatment Special problems and populations -- Addresses suicide, substance abuse, violence, dissociative states, defensive functioning, gender and cross-cultural issues, and patients in correctional and medical settings New developments and future directions -- Offers perspectives on brain imaging and translational research and asserts that the closer working relationship between clinical psychiatrists and behavioral neuroscientists -- with neuroimaging techniques as the common ground -- will result in more promising models to enhance our understanding of the neuroscience and molecular biology of personality disorders Offering both a wealth of practical information that clinicians can use right away in their daily practice and an up-to-date review of empirical research, The American Psychiatric Publishing Textbook of Personality Disorders is the definitive reference and clinical guide not only for seasoned clinicians but also for psychiatry residents, psychology interns and graduate students, and social work, medical, and nursing students.
Stepped Care For Borderline Personality Disorder
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Author : Joel Paris
language : en
Publisher: Academic Press
Release Date : 2017-08-23
Stepped Care For Borderline Personality Disorder written by Joel Paris and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-08-23 with Psychology categories.
Synthesizing the latest research and treatment developments, Stepped Care for Borderline Personality Disorder: Making Treatment Brief, Effective, and Accessible aims to make treatment for borderling personality disorder (BPD) more accessible by providing clinicians with innovative brief and targeted intervention methods. Focusing on integrative treatment models, it offers clinicians a vital guide to the management of patients who are difficult to treat. Acknowleding the early developmental roots of BPD, the book includes sections on BPD in adolescence, childhood precursors of the disorder, and a broad range of etiological factors. It looks at the pitfalls clinicians face when trying to treat BPD, and offers a roadmap to avoiding them. Brief and targeted methods of integrative treatment for BPD patients Makes treatment more accessible to a wider range of patients Provides clinicians and researchers with a review of the current BPD literature Offers solutions to the problem of treatment access for BPD patients Addresses questions regarding the complex developmental trajectories of BPD Presents a model of stepped care treatment of BPD and describes research on its effectiveness
Clinical Handbook For The Management Of Mood Disorders
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Author : J. John Mann
language : en
Publisher: Cambridge University Press
Release Date : 2013-05-09
Clinical Handbook For The Management Of Mood Disorders written by J. John Mann and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-05-09 with Medical categories.
Provides a one-stop evidence-based guide to the management of all types of mood disorders.
The Treatment Of Bipolar Disorder
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Author : André F. Carvalho
language : en
Publisher: Oxford University Press
Release Date : 2017-03-01
The Treatment Of Bipolar Disorder written by André F. Carvalho and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-03-01 with Medical categories.
Bipolar disorder is a chronic and debilitating mental illness affecting a significant proportion of the world's population. It is associated with significant impairments in health-related quality of life and psychosocial functioning, and has significant illness-related morbidity and heightened mortality rates due to medical comorbidities and suicide. The management of this disorder requires a complex combination of pharmacological and psychosocial interventions which can be challenging for clinicians. Written by world experts in the field of bipolar disorder, The Treatment of Bipolar Disorder: Integrative Clinical Strategies and Future Directions provides readers with a concise and comprehensive guide to the integrative management of bipolar disorder. This resource contains 31 chapters on the various management choices available, from both established and novel treatment areas, such as psychoeducation, psychotherapeutic interventions, neuromodulatory approaches and novel therapeutic targets. The complexity and diversity of the management choices available makes this a continually evolving field and necessitates forward thinking. By both discussing the current management of bipolar disorder, and the future developments available, this resource provides all clinicians working with patients with bipolar disorder an up-to-date and reflective guide to its management and what the future holds.
Sleep And Mental Illness
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Author : S. R. Pandi-Perumal
language : en
Publisher: Cambridge University Press
Release Date : 2010-04-01
Sleep And Mental Illness written by S. R. Pandi-Perumal and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-04-01 with Medical categories.
The diagnosis of mental illness is frequently accompanied by sleep problems; conversely, people experiencing sleep problems may subsequently develop mental illness. Sleep and Mental Illness looks at this close correlation and considers the implications of research findings that have emerged in the last few years. Additionally, it surveys the essential concepts and practical tools required to deal with sleep and co-morbid psychiatric problems. The volume is divided into three main sections: basic science, neuroendocrinology, and clinical science. Included are over 30 chapters on topics such as neuropharmacology, insomnia, depression, dementia, autism, and schizophrenia. Relevant questionnaires for the assessment of sleep disorders, including quality-of-life measurement tools, are provided. There is also a summary table of drugs for treating sleep disorders. This interdisciplinary text will be of interest to clinicians working in psychiatry, behavioral sleep medicine, neurology, pulmonary and critical care medicine.