Pathogenesis And Surgical Treatment Of The Middle Ear Cholesteatoma
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Pathogenesis And Surgical Treatment Of The Middle Ear Cholesteatoma
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Author :
language : en
Publisher:
Release Date : 1978
Pathogenesis And Surgical Treatment Of The Middle Ear Cholesteatoma written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1978 with categories.
Pathogenesis And Surgical Treatment Of The Middle Ear Cholesteatoma
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Author : Luzius Rüedi
language : en
Publisher:
Release Date : 1979
Pathogenesis And Surgical Treatment Of The Middle Ear Cholesteatoma written by Luzius Rüedi and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1979 with Cholesteatoma categories.
Middle Ear Cholesteatoma
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Author : Johanna Westerberg
language : en
Publisher: Linköping University Electronic Press
Release Date : 2020-09-29
Middle Ear Cholesteatoma written by Johanna Westerberg and has been published by Linköping University Electronic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-09-29 with categories.
Cholesteatomas are bone destructive expansions of keratinizing squamous epithelium in the middle ear and temporal bone. Today, surgery is the only treatment. There are several controversies regarding cholesteatomas, including the definition, the pathogenesis and the surgical method. Intense efforts have been made searching for a comprehension of the cholesteatoma process at a cellular and molecular level. Recurrent infections and inflammation seem to be contributing factors for the cholesteatomas to expand. The innate immunity, essential to keep a healthy middle ear environment and to protect the middle ear from intruding pathogens, is therefore a matter of interest. In this thesis, results are presented from a cohort of cholesteatoma surgeries in Östergötland from a 16-year period. A group of patients also filled in a questionnaire to assess changes in health-related quality of life (HRQoL) after surgery. According to the findings in this thesis, the residual and recurrence frequencies are low, and the hearing and HRQoL are improved in the majority of cases. This thesis also presents an investigation of the innate immunity in ears with acquired cholesteatoma, in comparison with healthy controls. The expression of mRNA of toll-like receptors 2 and 4, participants of the Janus kinase/signal transducer and activator of transcription pathway, and nitric oxide synthases in middle ear mucosa, were investigated with quantitative polymerase chain reaction. An investigation of nitric oxide (NO) in the middle ear, with chemiluminescence measurements, is also presented. A derangement of the innate immune system is seen in ears with cholesteatoma, which supports the idea that the innate immunity participates in the cholesteatoma process, though the underlying mechanisms are still unclear. The suggestion of NO production in the middle ear sheds light on NOs possible participation in the healthy middle ear environment.
Cholesteatoma And Anterior Tympanotomy
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Author : Tamotsu Morimitsu
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Cholesteatoma And Anterior Tympanotomy written by Tamotsu Morimitsu and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Acquired aural cholesteatoma poses a unique procedural dilemma with regard to pathogenetic research and theory building. Because cholesteatoma spontane ously occurs only in the poorly pneumatized human ear, its pathogenesis is specific to humans. Nonetheless, because of the ethical questions surrounding human experimentation, pathogenetic study has almost exclusively involved nonhuman subjects. Indeed, attempts have failed in almost all animal expe riments except with the gerbil, and even here experimental designs have been improbable compared with human cholesteatoma. Cholesteatoma in the gerbil is useful, therefore, only for the study of pathology and not for human pathogenesis. I hold that the pathogenesis of cholesteatoma will be understood by studying the cholesteatomatous ear, that is, the malpneumatized ear of the human. The anatomical difference between the normal and malpneumatized ear is a probable cause of cholesteatoma. This difference may be found clinically in facial nerve decompression and cholesteatoma surgery, as, for example, facial nerve palsy occurs usually in the normal, well-pneumatized ear. Of course, conventional animal experimentation will not confirm this clinical difference since there is no ideal animal model for the poorly pneumatized human ear. Present surgical techniques for cholesteatoma vary greatly according to indi vidual otosurgeon's opinion. The most extreme difference of opinion is focused on whether to remove the external ear canal wall. Normally, the best option would be not to remove the canal wall if cholesteatoma recurrence can be prevented. Simply put, recurrence of cholesteatoma comes about when its cause has not been removed during primary surgery.
Surgical Treatment Of Middle Ear Cholesteatoma
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Author : Michel Wayoff
language : en
Publisher: S Karger Ag
Release Date : 1987
Surgical Treatment Of Middle Ear Cholesteatoma written by Michel Wayoff and has been published by S Karger Ag this book supported file pdf, txt, epub, kindle and other format this book has been release on 1987 with Medical categories.
Pathogenesis In Cholesteatoma
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Author : Bernard Ars
language : en
Publisher: Kugler Publications
Release Date : 1999
Pathogenesis In Cholesteatoma written by Bernard Ars and has been published by Kugler Publications this book supported file pdf, txt, epub, kindle and other format this book has been release on 1999 with Medical categories.
Cholesteatoma
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Author : Eric E. Smouha
language : en
Publisher: Thieme
Release Date : 2011-10-28
Cholesteatoma written by Eric E. Smouha and has been published by Thieme this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-10-28 with Medical categories.
Master the challenges of cholesteatoma management with this definitive reference Thieme congratulates Eric E. Smouha on being chosen by New York magazine for its prestigious Best Doctors 2015 list. In this succinctly-organized text, leading specialists have created a comprehensive guide to cholesteatoma and chronic ear disease. Based on the bestselling AAO-HNS course, Cholesteatoma provides in-depth advice for the medical and surgical management of this middle ear entity. Cholesteatoma begins with an introduction of the disease and its general considerations, including preoperative assessment, the role of imaging, and the wet ear. Comprehensive chapters then present the three components of middle ear surgery which are the middle ear, the mastoid, and the meatus and the resultant cavity. The expert authors provide perspective on the controversies in cholesteatoma management like canal wall reconstruction, facial nerve monitoring, the use of endoscopes in chronic ear surgery, and postoperative care. Features: Accompanying online media includes 20 surgical videos performed and narrated by the authors More than 340 vibrant full-color illustrations demonstrate the different disease progressions not shown in any other text Insightful chapters cover recidivism and complications of both the disease and surgery, while O.R. cases illustrate surgical approaches Otolaryngology-head and neck surgeons, residents and fellows will refer to this concise reference on a daily basis for the most up-to-date information on cholesteatomas and other middle ear lesions.
Microsurgical Management Of Middle Ear And Petrous Bone Cholesteatoma
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Author : Mario Sanna
language : en
Publisher: Thieme
Release Date : 2019-07-10
Microsurgical Management Of Middle Ear And Petrous Bone Cholesteatoma written by Mario Sanna and has been published by Thieme this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-07-10 with Medical categories.
The key reference dedicated to surgery for cholesteatoma... The cholesteatoma, strictly speaking a cyst and not a cancer, nevertheless shows expansive and destructive growth patterns that may give rise to serious symptoms and consequences, including fatality, not unlike those seen for malignant neoplasms. The great challenge of therapy is to eradicate the pathologic growth while preserving hearing and other critical functions of the middle ear and petrous bone, respecting the proximity of vital neural and vascular structures, and the intricate three-dimensional relationships involved. Mario Sanna's Microsurgical Management of Middle Ear and Petrous Bone Cholesteatoma is the ultimate illustrated guide to complete management of the cholesteatoma, including assessment of the full expansion and degree of destruction caused by the growths, and short- and long-term follow-up to assess and treat for recurrence. Key Features Brilliantly illustrated with diagnostic images from otoscopy and radiology, both normal and pathological Step-by-step description of approaches and techniques for the procedures Special coverage of petrous bone cholesteatoma, which is less frequent than other forms but more difficult to diagnose and treat, with introduction and description of a new function-sparing procedure, the subtotal petrosectomy Microsurgical Management of Middle Ear and Petrous Bone Cholesteatoma extends Mario Sanna's passionate dedication to excellence in otologic teaching and training into this highly complex surgical area. Practitioners, residents, and fellows will find it indispensable.
Tympanic Membrane Retraction Pocket
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Author : Salah Mansour
language : en
Publisher: Springer
Release Date : 2015-02-27
Tympanic Membrane Retraction Pocket written by Salah Mansour and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-02-27 with Medical categories.
This book reviews current knowledge of the etiopathogenesis, pathophysiology, and molecular biology of tympanic membrane retraction pockets and provides clear guidance on clinical assessment and treatment. A new diagnostic approach based on clinicoradiologic correlations is presented, and the ability of computer tomography to offer objective criteria for improved differentiation between stable and unstable or unsafe retraction pockets is explained. Surgical options are discussed, and on the basis of their own clinical and surgical experiences the authors propose a novel procedure, masto-atticotomy with anterior epitympanotomy (AER surgery), which addresses the causative factors underlying a retraction pocket. This surgery aims to restore adequate aeration routes for the middle ear compartments situated above the tympanic diaphragm; it results in better control of the pathology and in most cases prevents its recurrence. The book will assist otologists and surgeons in ensuring that retraction pockets are effectively diagnosed and treated, avoiding progression to cholesteatoma.
The Middle Ear
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Author : H. Takahashi
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
The Middle Ear written by H. Takahashi and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
For the middle ear to maintain its most important function, sound con duction, its pressure always needs to be kept around atmospheric level. The eustachian tube has long been believed to be the only organ playing the important role of pressure regulation of the middle ear. However, several phenomena that cannot be explained solely by reference to eustachian tube function have gradually emerged. For instance, otitis media with effusion cannot always be produced experimentally by selectively eliminating the ventilatory function of the eustachian tube by excising the tensor veli pala tini muscle and the hamulus pterygoideus. Also, most cases of otitis media with effusion (OME) in children can heal in spite of persistently poor tubal function even in the convalescent stage. In recent decades, gas exchange in the middle ear, particularly through the mastoid mucosa, has gradually come to light as another ventilation or pressure-regulation system for the middle ear. Although numbers of studies have revealed important information about the physiology and patho physiology of this function, there have been only a few studies related to gas exchange that directly contributed to the field of clinical otology by clarifying the pathogenesis of otitis media or to improving its treatment. One of the biggest reasons for the paucity of studies appears to be lack of an appropriate clinical method for assessing the gas exchange function.