Pemphigus And Pemphigoid Diseases In Memoriam Detlef Zillikens

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Pemphigus And Pemphigoid Diseases In Memoriam Detlef Zillikens

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Author : Ralf J. Ludwig
language : en
Publisher: Frontiers Media SA
Release Date : 2024-06-19

Pemphigus And Pemphigoid Diseases In Memoriam Detlef Zillikens written by Ralf J. Ludwig and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-06-19 with Medical categories.

Pemphigus and pemphigoid diseases are a heterogenous group of autoimmune blistering disorders (AIBD) characterized by tissue-bound and circulating autoantibodies against structural proteins of the desmosome and basement membrane zone of the skin and orifice-close mucosal tissues. While strong evidence has been provided that autoantibodies in AIBD are pathogenic, the exact mechanisms of how blister formation is mediated is very different between pemphigus and pemphigoid disorders and yet incompletely understood. Additionally, target antigens for the major AIBDs have already been identified on the molecular level. In contrast, diagnostic assays are not yet available for all autoantibody specificities and isotypes. Treatment also greatly relies on long-term unspecific immunosuppressants, although rituximab has greatly improved the outcome for patients with moderate and severe pemphigus. There is currently still a need to identify key pathophysiological mediators and pathways for the development of more specific, safer, and more effective treatment options. This Research Topic will honor the work of the late Detlef Zillikens, who has dedicated over 30 years to the field of AIBD and has authored more than 600 articles. We strongly encourage the submission of articles from colleagues and researchers who have collaborated with Prof. Zillikens in the past, however, we will also consider manuscripts from other authors. We would particularly like articles to cite Prof. Zillikens work wherever it is appropriate. We welcome the submission of original research and review articles that cover, but are not limited to, the following sub-topics: • autoantibody specificities • diagnostic assays • in vitro or in vivo studies about the effect of autoantibodies and their modulation • epidemiology and treatment of AIBD Reports of individual cases are discouraged Dr. Enno Schmidt receives grant funding from Euroimmun, Incyte, Dompe, Admirx, Synthon/biondis, Bayer, Pharmix, Alpine Immune, AstraZeneca, Sanofi, ArgenX, UCB, Novartis, Biotest, Fresenius Medical Care, and is consulting for Roche, Imevax, Thermo Fisher, Janssen, Topas, Bristol-Myers Squibb, Almirall, and Chugai. The other Topic Editors declare no potential competing interests in relation to the Research Topic theme.

Defects In Regulation How Where And When The Immune System Can Go Wrong

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Author : Ger Rijkers
language : en
Publisher: Frontiers Media SA
Release Date : 2022-02-03

Defects In Regulation How Where And When The Immune System Can Go Wrong written by Ger Rijkers and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-02-03 with Medical categories.

Advances In Pathogenesis Etiology And Therapies For Ankylosing Spondylitis

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Author : Jieruo Gu
language : en
Publisher: Frontiers Media SA
Release Date : 2022-02-10

Advances In Pathogenesis Etiology And Therapies For Ankylosing Spondylitis written by Jieruo Gu and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-02-10 with Medical categories.

Immune Related Non Communicable Diseases In Africa

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Author : Mohamed-Ridha Barbouche
language : en
Publisher: Frontiers Media SA
Release Date : 2022-02-17

Immune Related Non Communicable Diseases In Africa written by Mohamed-Ridha Barbouche and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-02-17 with Medical categories.

Autoimmune Diseases Of The Skin

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Author : Michael Hertl
language : en
Publisher: Springer Science & Business Media
Release Date : 2005-08-19

Autoimmune Diseases Of The Skin written by Michael Hertl and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-08-19 with Medical categories.

Autoimmune disorders of the skin remain an enigma for many clinicians and scientists not familiar with these mostly severe and chronic diseases. The book provides an overview and the latest information on the broad spectrum of cutaneous autoimmune disorders for clinicians, scientists and practitioners in dermatology, medicine, rheumatology, ENT, pediatrics and ophthalmology. The book is unique since it presents the state-of-the-art knowledge on pathophysiology, clinical diagnosis and management of these disorders provided by the world experts in the field. The primary intention is to broaden the understanding of the pathophysiology of cutaneous autoimmune disorders and to provide a practical guide to how to identify and handle these conditions. The book is illustrated with many tables, illustrative figures and clinical color photographs. The second edition has been extended by chapters on autoimmune pigmentary disorders (vitiligo), hairloss (alopecia areata) and cutaneous symptoms of rheumatic disorders.

Textbook Of Autoinflammation

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Author : Philip J. Hashkes
language : en
Publisher: Springer
Release Date : 2019-02-13

Textbook Of Autoinflammation written by Philip J. Hashkes and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-02-13 with Medical categories.

This book, the first complete textbook on this novel field in Medicine, comprehensively covers the clinical presentation, pathogenesis, genetics, and latest management strategies for autoinflammatory disorders as well as the basic science of autoinflammation. Relevant concepts such as how translational science of genetics and immunology relates to the innate immune system and autoinflammation are covered. Descriptions of the monogenic and polygenic/complex diseases that fall under the umbrella of autoinflammatory diseases are provided. Further topics covered include the latest clinical and genetic diagnostic approaches, concepts on the relationship between autoinflammation and autoimmunity/immunodeficiency, the role of autoinflammation in cancer, treatments and management strategies for these diseases, and potential areas of future development. The Textbook of Autoinflammation systematically describes and reviews diagnostic and treatment options for autoinflammatory disorders as well as all aspects of the concept of autoinflammation, and represents a valuable resource for professionals in a variety of disciplines who encounter these patients or who study autoinflammation.

Bullous Diseases

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Author : Thomas T. Provost
language : en
Publisher: Mosby Elsevier Health Science
Release Date : 1993

Bullous Diseases written by Thomas T. Provost and has been published by Mosby Elsevier Health Science this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993 with Medical categories.

Pediatric Dermatology

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Author :
language : en
Publisher:
Release Date : 1992

Pediatric Dermatology written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992 with categories.

Skin And The Heart

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Author : Carmen Salavastru
language : en
Publisher: Springer Nature
Release Date : 2021-03-10

Skin And The Heart written by Carmen Salavastru and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-03-10 with Medical categories.

This book describes the relationship of the skin with cardiovascular disease. It details the variety of genetic, autoimmune, metabolic and endocrine factors that link the two disciplines. Recognition of one sign or symptom in dermatology can lead to the investigation and discovery of an important related cardiac condition, the recognition of which is important to prevent cardiovascular complications. Similarly, a cardiac condition may be related to an underlying skin condition that requires treatment. Genetic examples of such instances included within the book include: pseudoxanthoma elasticum, epidermolysis bullosa with desmosome defects and plectin defects; Marfan syndrome; Autoimmune conditions include vasculitis, sarcoidosis, lupus; metabolic conditions include insulin resistance, eruptive xanthomas with hypertriglyceridemias and elevated cholesterol; endocrine disorders include thyroid acropachy with atrial fibrillation; insulin resistance with coronary artery disease and psoriasis or hidradenitis suppurativa. Skin and the Heart reviews the effects of genetic, autoimmune and endocrine diseases with connections between skin and heart. It is therefore a key reference for all practitioners and researchers working in both disciplines.

Clinical Approach To Fungal Infections

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Author : Kabir Sardana MD, DNB, MNAMS
language : en
Publisher: CBS Publishers & Distributors Private Limited
Release Date : 2019-06-30

Clinical Approach To Fungal Infections written by Kabir Sardana MD, DNB, MNAMS and has been published by CBS Publishers & Distributors Private Limited this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-06-30 with categories.

This is the first book on fungal infections of the skin pertaining to the Indian conditions. It covers all important aspects of the topics, including superficial and deep systemic fungal infection and anti fungal drugs.