Pfizer Global Research And Development Scientific Publications 2000
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Pfizer Global Research And Development Scientific Publications 2000
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Author :
language : en
Publisher:
Release Date : 2000
Pfizer Global Research And Development Scientific Publications 2000 written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000 with Pharmaceutical chemistry categories.
Research And Development In The Pharmaceutical Industry A Cbo Study
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Author : Congressional Budget Office
language : en
Publisher: Lulu.com
Release Date : 2013-06-09
Research And Development In The Pharmaceutical Industry A Cbo Study written by Congressional Budget Office and has been published by Lulu.com this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-09 with Science categories.
Perceptions that the pace of new-drug development has slowed and that the pharmaceutical industry is highly profitable have sparked concerns that significant problems loom for future drug development. This Congressional Budget Office (CBO) study-prepared at the request of the Senate Majority Leader-reviews basic facts about the drug industry's recent spending on research and development (R&D) and its output of new drugs. The study also examines issues relating to the costs of R&D, the federal government's role in pharmaceutical research, the performance of the pharmaceutical industry in developing innovative drugs, and the role of expected profits in private firms' decisions about investing in drug R&D. In keeping with CBO's mandate to provide objective, impartial analysis, the study makes no recommendations. David H. Austin prepared this report under the supervision of Joseph Kile and David Moore. Colin Baker provided valuable consultation...
Breakthrough Business Models
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Author : Institute of Medicine
language : en
Publisher: National Academies Press
Release Date : 2009-03-17
Breakthrough Business Models written by Institute of Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-03-17 with Medical categories.
The process for developing new drug and biologic products is extraordinarily expensive and time-consuming. Although large pharmaceutical companies may be able to afford the cost of development because they can expect a large return on investment, organizations developing drugs to treat rare and neglected diseases are unable to rely on such returns. On June 23, 2008, the Institute of Medicine's Forum on Drug Discovery, Development, and Translation held a public workshop, "Breakthrough Business Models: Drug Development for Rare and Neglected Diseases and Individualized Therapies," which sought to explore new and innovative strategies for developing drugs for rare and neglected diseases.
The Pharmaceutical Studies Reader
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Author : Sergio Sismondo
language : en
Publisher: John Wiley & Sons
Release Date : 2015-05-11
The Pharmaceutical Studies Reader written by Sergio Sismondo and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-05-11 with Social Science categories.
The Pharmaceutical Studies Reader is an engaging survey of the field that brings together provocative, multi-disciplinary scholarship examining the interplay of medical science, clinical practice, consumerism, and the healthcare marketplace. Draws on anthropological, historical, and sociological approaches to explore the social life of pharmaceuticals with special emphasis on their production, circulation, and consumption Covers topics such as the role of drugs in shaping taxonomies of disease, the evolution of prescribing habits, ethical dimensions of pharmaceuticals, clinical trials, and drug research and marketing in the age of globalization Offers a compelling, contextually-rich treatment of the topic that exposes readers to a variety of approaches, ideas, and frameworks Provides an accessible introduction for readers with no previous background in this area
Conflict Of Interest In Medical Research Education And Practice
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Author : Institute of Medicine
language : en
Publisher: National Academies Press
Release Date : 2009-10-16
Conflict Of Interest In Medical Research Education And Practice written by Institute of Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-10-16 with Medical categories.
Collaborations of physicians and researchers with industry can provide valuable benefits to society, particularly in the translation of basic scientific discoveries to new therapies and products. Recent reports and news stories have, however, documented disturbing examples of relationships and practices that put at risk the integrity of medical research, the objectivity of professional education, the quality of patient care, the soundness of clinical practice guidelines, and the public's trust in medicine. Conflict of Interest in Medical Research, Education, and Practice provides a comprehensive look at conflict of interest in medicine. It offers principles to inform the design of policies to identify, limit, and manage conflicts of interest without damaging constructive collaboration with industry. It calls for both short-term actions and long-term commitments by institutions and individuals, including leaders of academic medical centers, professional societies, patient advocacy groups, government agencies, and drug, device, and pharmaceutical companies. Failure of the medical community to take convincing action on conflicts of interest invites additional legislative or regulatory measures that may be overly broad or unduly burdensome. Conflict of Interest in Medical Research, Education, and Practice makes several recommendations for strengthening conflict of interest policies and curbing relationships that create risks with little benefit. The book will serve as an invaluable resource for individuals and organizations committed to high ethical standards in all realms of medicine.
Green Chemistry In The Pharmaceutical Industry
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Author : Peter J. Dunn
language : en
Publisher: John Wiley & Sons
Release Date : 2010-02-02
Green Chemistry In The Pharmaceutical Industry written by Peter J. Dunn and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-02-02 with Science categories.
Edited by three of the world's leading pharmaceutical scientists, this is the first book on this important and hot topic, containing much previously unpublished information. As such, it covers all aspects of green chemistry in the pharmaceutical industry, from simple molecules to complex proteins, and from drug discovery to the fate of pharmaceuticals in the environment. Furthermore, this ready reference contains several convincing case studies from industry, such as Taxol, Pregabalin and Crestor, illustrating how this multidisciplinary approach has yielded efficient and environmentally-friendly processes. Finally, a section on technology and tools highlights the advantages of green chemistry.
Medical Imaging
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Author : Mostafa Analoui
language : en
Publisher: CRC Press
Release Date : 2012-11-08
Medical Imaging written by Mostafa Analoui and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-11-08 with Medical categories.
The discovery of x-ray, as a landmark event, enabled us to see the "invisible," opening a new era in medical diagnostics. More importantly, it offered a unique undestanding around the interaction of electromagnetic signal with human tissue and the utility of its selective absorption, scattering, diffusion, and reflection as a tool for understanding
Maternal Immunization
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Author : Elke Leuridan
language : en
Publisher: Academic Press
Release Date : 2019-11-26
Maternal Immunization written by Elke Leuridan and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-26 with Medical categories.
Immunization during pregnancy with currently recommended vaccines prevents infection in the mother, the unborn fetus, and the young infant, and there is an increasing focus from different stakeholders to use this approach for other infections of importance to protect these vulnerable groups. The aim of this Maternal Immunization book is to provide a contemporary overview of vaccines used in pregnancy (and the lactation period), with emphasis on aspects of importance for the target groups, namely, rationale for the use of vaccines in pregnancy, safety, immunogenicity (immunology), timing to vaccinate, repeat doses, protective effects in the mother, fetus, and infant, and public acceptance and implementation, of existing and of future vaccines. Provides an overview of a quickly evolving topic. This will benefit the reader who wishes to rapidly become informed and up-to-date with new developments in this field Suitable to a broad audience: scientific researchers, obstetricians, gynecologists, neonatologists, vaccinators, pediatricians, students, and industry. Maternal vaccination impacts a wide range of specialists Allows health care professionals/researchers to gain insight into other aspects of vaccination in pregnancy outside of their specialism Is coauthored by specialists from multiple disciplines, providing a diverse view of the subject, increasing its interest and appeal Creates awareness of the current developments in this area of medicine and of the potential of maternal vaccination to improve the health of mothers and infants worldwide
Optical Coherence Tomography In Cardiovascular Research
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Author : Evelyn Regar
language : en
Publisher: CRC Press
Release Date : 2007-03-06
Optical Coherence Tomography In Cardiovascular Research written by Evelyn Regar and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-03-06 with Medical categories.
Given that for centuries, the standard tool to understand diseases in tissues was the microscope and that its major limitation was that only excised tissue could be used, recent technology now permits the examination of diseased tissue in vivo. Optical coherence tomography (OCT) has promising potential when applied to coronary artery disease. OCT has the capability to identify coronary plaque and to distinguish between plaques that are stable and unstable. If the plaques are stable then OCT can direct percutaneous intervention (angioplasty or stenting). Optical coherence tomography is a light-based imaging technology that allows for very high resolution imaging in biological tissues. It has been first applied in ophthalmology, where it soon became the golden standard for the assessment of (epi-) retinal processes. The unique imaging capabilities have raised the interest of researchers and clinicians in the field of cardiovascular disease, since OCT offers unique possibilities to study atherosclerosis pathophysiology in vivo. With over 1.1M Americans having a heart attack this year because of unstable plaque rupture, OCT may have an increasingly important role in the early diagnosis of coronary artery disease. This unique publication offers the reader the basic background to OCT and its role in the diagnosis and management of coronary artery disease. The Handbook of Optical Coherence Tomography in Cardiovascular Research introduces the cardiovascular application of this technology. Clinicians, biologists, engineers and physicist are discussing different aspects of cardiovascular OCT application in a multidisciplinary approach. The handbook offers the readership a concise overview on the current state of the art of vascular OCT imaging and sheds light on a variety of exciting new developments. The physics, technical principles of OCT and its application in a broad spectrum of cardiovascular research areas are summarized by highly recognized specialists. The potential of OCT in peripheral and coronary arteries and in developmental cardiology are described. Each research area is introduced by a clinical expert in the field followed by discussion of different aspects from an engineering, biomedical and clinical perspective. Specifically, the current capabilities for plaque characterization, detection of vulnerable plaque, guidance of interventional procedures, Doppler-assessment, and molecular contrast imaging are being described. The Handbook of Optical Coherence Tomography in Cardiovascular Research targets researchers and clinicians involved in the field of atherosclerosis. The summary of basic physics, engineering solutions, pre-clinical and clinical application covers all relevant aspects and will be a valuable reference source.
Handbook Of Isolation And Characterization Of Impurities In Pharmaceuticals
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Author : Satinder Ahuja
language : en
Publisher: Elsevier
Release Date : 2003-06-26
Handbook Of Isolation And Characterization Of Impurities In Pharmaceuticals written by Satinder Ahuja and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-06-26 with Medical categories.
The United States Food and Drug Administration (FDA) and other regulatory bodies around the world require that impurities in drug substance and drug product levels recommended by the International Conference on Harmonisation (ICH) be isolated and characterized. Identifying process-related impurities and degradation products also helps us to understand the production of impurities and assists in defining degradation mechanisms. When this process is performed at an early stage, there is ample time to address various aspects of drug development to prevent or control the production of impurities and degradation products well before the regulatory filing and thus assure production of a high-quality drug product.This book, therefore, has been designed to meet the need for a reference text on the complex process of isolation and characterization of process-related (synthesis and formulation) impurities and degradation products to meet critical requlatory requirements.It's objective is to provide guidance on isolating and characterizing impurities of pharmaceuticals such as drug candidates, drug substances, and drug products. The book outlines impurity identification processes and will be a key resource document for impurity analysis, isolation/synthesis, and characterization. - Provides valuable information on isolation and characterization of impurities. - Gives a regulatory perspective on the subject. - Describes various considerations involved in meeting regulatory requirements. - Discusses various sources of impurities and degredation products.